| 甲硝唑的电化学性质及其伏安法测定 |
| |
| 引用本文： | 金根娣,吕雅梅.甲硝唑的电化学性质及其伏安法测定[J].扬州职业大学学报,2010,14(1):43-45,52. |
| |
| 作者姓名： | 金根娣 吕雅梅 |
| |
| 作者单位： | 1. 扬州职业大学,江苏,扬州,225009
2. 扬州大学,江苏,扬州,225002 |
| |
| 摘 要： | 在0.01 mol·L^-1的NaOH溶液中用玻碳电极研究甲硝唑的电化学性质,并用循环伏安法和示差脉冲伏安法对其含量进行测定。结果表明：甲硝唑在-0.631V和-0.731V处有一对明显的氧化还原峰,其还原峰电流与甲硝唑的浓度在8.0×10^-6-9.1×10^-4mol·L^-1（r=0.998）呈良好的线性关系,检出限为1.4×10^-7mol·L^-1。平均回收率98.9%,RSD=2.7%。甲硝唑在玻碳电极上的电化学行为受吸附控制。
|
| 关 键 词： | 玻碳电极（GCE） 甲硝唑 示差脉冲伏安法 循环伏安法 |
The Electrochemical Property of Metronidazole and Its Determination by Voltammetry |
| |
| JIN Gen-di,LV Ya-mei.The Electrochemical Property of Metronidazole and Its Determination by Voltammetry[J].Journal of Yangzhou Polytechnic College,2010,14(1):43-45,52. |
| |
| Authors: | JIN Gen-di LV Ya-mei |
| |
| Institution: | JIN Gen-di1,LV Ya-mei2 (1.Yangzhou Polytechnic College,Yangzhou 225009,China,2.Chemical Coll.Yangzhou University,Yangzhou 225002,China) |
| |
| Abstract: | The electrochemical property of metronidazole（MTZ） was researched in 0.01 mol·L^-1NaOH by the differential pulse voltammetry（DPV） and cyclic voltammetry（CV） with a glassy carbon electrode（GCE）.A couple of oxidation and reduction peak appeared in-0.631V and-0.731V respectively.The reduction peak current was linear with the concentration of metronidazole in the range of 8.0×10^-6～9.1×10^-4mol·L^-1（r=0.998）,and the detection limit was 1.4×10^-7mol·L^-1.The average recovery was 98.9 %,RSD=2.7 %.Metronidazole also showed adsorption characteristics at the electrode.This method was applied in detecting the content of metronidazole sample.The results obtained by this method were in conformity with the results found by pharmacopoeia method. |
| |
| Keywords: | glassy carbon electrode(GCE) metronidazole(MTZ) differential pulse voltammetry(DPV) cyclic voltammetry(CV) |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
