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金属硫蛋白在消化管腺癌中表达的临床意义
引用本文:白金君,薄爱华.金属硫蛋白在消化管腺癌中表达的临床意义[J].河北北方学院学报(医学版),2008,25(2):21-23.
作者姓名:白金君  薄爱华
作者单位:1. 河北省沧州中西结合医院,河北,沧州,061001
2. 河北北方学院实验中心电镜室,河北,张家口,075000
基金项目:河北省张家口市科学技术研究与发展指导计划
摘    要:目的:探讨金属硫蛋白在食管鳞状细胞癌(ESC)、胃腺癌(GTAC)、大肠腺癌(LITAC)中的表达及意义。方法:利用免疫组织化学法,检测194例消化管癌组织中MT表达率。结果:MT在食管癌、胃癌、肠癌中的阳性率分别为75.00%(24/32),52.27%(46/88),59.46%(44/74)。癌组织分化程度低和浸润深者MT阳性率高于中、高分化组和浸润浅组(P<0.05)。结论:MT表达与癌组织分化程度和浸润深度有关。

关 键 词:金属硫蛋白  食管肿瘤  胃肿瘤  肠肿瘤
文章编号:1673-1484(2008)02-0021-03

Clinical Significance on the Expression of Metallothionein in Digestive Tubal Carcinonca
BAI Jin-jun,BO Ai-hua.Clinical Significance on the Expression of Metallothionein in Digestive Tubal Carcinonca[J].Journal of Hebei North University:Medical Edition,2008,25(2):21-23.
Authors:BAI Jin-jun  BO Ai-hua
Abstract:Objective:To study the expression of metallothonein and its effect in esphageal squarnous call cancer(ESC),gastraltubal adenocarcicma(GTAC) and large intestinal tubal adenocarcincma(LITAC).Methods:The expression rates of MT in 194 cases with digestive tubal carcinoma were detectived by immunohistochemical method.Results:The postive rates of MT in ESC,GTAC,LITAC were 75.00%,52.27%,59.46% respectively and the carcinoma Tissue for lous different and deel invasive patients was significantly higher than that of patients with high difference and light invasion(P<0.05).Conclusion:The expression rates of MT in digestive tubal cancer was related with diffierent degree and invasive depth degree of cancer tissue.
Keywords:Metallothionein  Esophageal Neoplasms  Stomach Neoplasms  Intestinal Neoplasms
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