| 潘南金对急性心肌梗塞心律失常影响的对比研究 |
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| 引用本文： | 余清,姚计文,金刚,程育博,赵东辉,柳宏杰.潘南金对急性心肌梗塞心律失常影响的对比研究[J].河北北方学院学报(医学版),2001,18(4):11-14. |
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| 作者姓名： | 余清 姚计文 金刚 程育博 赵东辉 柳宏杰 |
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| 作者单位： | 北京燕山石化公司职工医院心内科,102500 |
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| 摘 要： | 目的观察潘南金(门冬氨酸钾镁)对急性心肌梗塞后心律失常、泵功能及死亡率的影响.方法本文对我院1998.3～1999.10月收入CCU病房的40例患者进行单盲、随机分为治疗组和对照组,治疗组第1～5天给予潘南金静脉输注,第6～15天改为口服,检测两组治疗前、第5、10天的血清钾、镁离子浓度,记录治疗前后血压及第一天24hHolter,统计两组并发症及死亡率,所得数据进行统计学处理.结果两组间在年龄、性别、发病时间及合并用药等方面无差异,所有资料具有可比性.治疗组第5、10天的血镁较治疗前及对照组显著增高(P＜0.01),治疗组的心衰、室早、室速较对照组明显减少(P值分别为＜0.05、＜0.01及＜0.05),治疗组再灌注心律失常发生率较对照组减少(P＜0.05),死亡率两组间无显著差异(P＜0.05).治疗组治疗前后血压变化较对照组明显(P＜0.05).结论潘南金可以减少AMI后心衰的发生,改善心功能,减少AMI后室性心律失常的发生.在溶栓的患者,潘南金能减少再灌注心律失常的发生,减小再灌注损伤.但潘南金对血压有较大的影响,尤其血压在正常低限时,静脉输注潘南金可使低血压发生率增加,因此临床应用时需注意.
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| 关 键 词： | 门冬氨酸钾镁 心肌梗塞 心律失常 |
| 文章编号： | 1005-8796(2001)04-011-04 |
Compariative investigation on effect of Panangin therapy in arrhythmia after acute myocardial infarction |
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| Yu Qing,Yao Jiwen,Jing Gang et al The Hospital of Yan Petrochemical Company,Beijing ,China.Compariative investigation on effect of Panangin therapy in arrhythmia after acute myocardial infarction[J].Journal of Hebei North University:Medical Edition,2001,18(4):11-14. |
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| Authors: | Yu Qing Yao Jiwen Jing Gang The Hospital of Yan Petrochemical Company Beijing China |
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| Institution: | Yu Qing,Yao Jiwen,Jing Gang et al The Hospital of Yan Petrochemical Company,Beijing 102500,China |
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| Abstract: | Objective: To investigate effect of Panangin(Kalii Magnesii Aspartas)theragy on arrhythmia, heart - pump function and mortality caused by acute myocardial infarction (AMI). Methods:40 AMI patients hospitalized in our CCU from March 1988 to October 1999 were randomly divided into two group: experimntal guoup and Control group. For experimental gronp, Panangin wal admistrated by different way for therapy, serum magnesium and Kalium were examined before and after panangin andmistration. Blood pressure changes. Holter idice, condition of Complications and mortality before and after therapy were also recorded and analy-sised.Resucts:The results showed: level of serum magnesium in panangin gronp was higher than that in control group after treatment (P<0. 01). Heart failure and ventricular arrhythmia could be significantly reduced by treating with panagin'in AMI patients. Arrhythmia after reperfusion in experimental group happened much less than that in control group (P<0. 05). There was no significant difference found in 4 - week rnortalith between these two group. Conclusion: Ventricular arrhythmia could be significantly reduced by panangin treatment in patients with AMI. Also panangin is also helpful for heart function restouing and prevent the heart failure. However. Panargin showld be used very carefully for its clown- regulating effect on blood pressure. |
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| Keywords: | Panangin Acute myocardial infarction Arrhythmia |
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