| 诱发溃疡性结肠炎动物模型化学方法及评价 |
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| 引用本文： | 王倩,田慧,张力.诱发溃疡性结肠炎动物模型化学方法及评价[J].河北北方学院学报(医学版),2013(4):23-28. |
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| 作者姓名： | 王倩 田慧 张力 |
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| 作者单位： | 河北北方学院药学系,中国张家口075000 |
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| 基金项目： | 国家自然科学基金项目（No.81274005） |
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| 摘 要： | 溃疡性结肠炎（ulcerative colitis,UC）又称慢性非特异性溃疡性结肠炎,流行病学资料提示溃疡性结肠炎的发病率在国内外都有逐年增高的趋势,溃疡性结肠炎的研究越来越受到国际肠病学家的关注,所以建立接近于人类的稳定的溃疡性结肠炎动物模型尤为重要。本文综述了近几年常用的诱发溃疡性结肠炎动物模型的化学方法及评价,以期为基础与临床研究应用提供参考。
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| 关 键 词： | 溃疡性结肠炎 动物模型 制备方法 评价 |
Animal Models of Ulcerative Colitis： A Review |
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| WANG Qian,TIAN Hui,ZHANG Li.Animal Models of Ulcerative Colitis： A Review[J].Journal of Hebei North University:Medical Edition,2013(4):23-28. |
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| Authors: | WANG Qian TIAN Hui ZHANG Li |
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| Institution: | (Department of Pharmacy, Hcbci North University, Zhangjiakou, 075000, China) |
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| Abstract: | Ulcerative colitis（UC） is also known as chronic nonspecific ulcerative colitis. Epidemiological data suggest that the incidence of ulcerative colitis both in domestic and abroad has increased annually,thus attracting increasing research attention. Establishing valid animal models of ulcerative colitis seems particularly critical. In this review,animal models of ulcerative colitis were reviewed in the hope to provide guidance for related basic and clinical research. |
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| Keywords: | ulcerative colitis animal models preparation methods evaluation |
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