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营养性巨幼细胞贫血巨核细胞及血小板参数的变化
引用本文:佟长青,赵麟成,张斌.营养性巨幼细胞贫血巨核细胞及血小板参数的变化[J].河北北方学院学报(医学版),2005,22(2):9-10.
作者姓名:佟长青  赵麟成  张斌
作者单位:河北北方学院附属第一医院血液科,河北,张家口,075000
基金项目:河北省张家口市科研项目
摘    要:目的:探讨营养性巨幼细胞贫血患者巨核细胞、血小板参数改变及其临床意义.方法:用显微镜检测巨核细胞,用血细胞自动分析仪测定4项血小板参数,并与对照组相比.结果:贫血组巨核细胞数正常或增多(P<0.05),平均血小板体积(MPV)、血小板体积分布宽度(PDW)增加,血小板计数(PLT)、血小板压积(PCT)减少,与对照组相比,差异具有显著性.结论:巨核细胞及血小板参数的变化是营养性巨幼细胞贫血的重要特征,且与功能相关,有助于临床鉴别诊断.

关 键 词:巨核细胞  血小板参数  巨幼细胞贫血
文章编号:1673-1484(2005)02-0009-02

The Changes of the Megakaryocyte and the Blood Platelet Parameters in Patients with Malnourished Megaloblastic Anemia
TONG Chang-qing,ZHAO Lin-cheng,ZHANG Bin.The Changes of the Megakaryocyte and the Blood Platelet Parameters in Patients with Malnourished Megaloblastic Anemia[J].Journal of Hebei North University:Medical Edition,2005,22(2):9-10.
Authors:TONG Chang-qing  ZHAO Lin-cheng  ZHANG Bin
Abstract:Objective:To study the changes and clinical significance of the megakaryocyte and the blood platelet parameters of patients with malnourished megaloblastic anemia. Methods: The megakaryocytes were assayed under microscope,and the 4 indexes of blood platelet parameters were determined by blood autoana-lyzer in 20 patients with malnourished megaloblastic anemia and compared with the normal control group. Results:The numbers of megakaryocyte in 20 patients were normal or increased (P<0. 05) ,MPV and PDW were increased,PLT and PCT decreased,and there were significantly difference than those of normal control group. Conclusion:The changes of the megakaryocyte and blood platelet parameters is an important characteristic in malnourished megaloblastic anemia,and is related with functions,which is constituted to differential diagnosis in clinic.
Keywords:megakaryocyte  blood platelet parameters  megaloblastic anemia
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