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消化道癌雌孕激素受体阴阳性细胞的超微结构比较
引用本文:戴洁,夏苓,邢立强,张振忠,么景满.消化道癌雌孕激素受体阴阳性细胞的超微结构比较[J].河北北方学院学报(医学版),1994(2).
作者姓名:戴洁  夏苓  邢立强  张振忠  么景满
作者单位:病理教研室、电镜室 (戴洁,夏苓,邢立强),一附院普外 (张振忠),一附院普外(么景满)
摘    要:取大肠管状腺癌Ⅱ级,无淋巴结转移者新鲜标本14例,以酶联组化法证实雌激素与孕激素受体均阳性者或均阴性者各7例,进行透射电镜下的超微结构观察。结果表明:受体阳性细胞、核暗、常染色质增多,呈细颗粒状,核仁以细颗粒状物为主。受体阴性细胞浆内游离核糖体明显增多。超微结构的不同提示两类癌细胞在代谢类型上存在着差异。

关 键 词:消化道肿瘤  雌激素受体  孕激素受体  超微结构

A COMPARATIVE STUDY ON UITRASTRUCTURK OF F.R-AND PR-POSITIVE AND NEGATIVE CANCER CELLS IN DIGETIVE TRACT
Dai Jic et al.A COMPARATIVE STUDY ON UITRASTRUCTURK OF F.R-AND PR-POSITIVE AND NEGATIVE CANCER CELLS IN DIGETIVE TRACT[J].Journal of Hebei North University:Medical Edition,1994(2).
Authors:Dai Jic
Institution:Dai Jic et al
Abstract:Samples from 14 cases with giade 2 of tubular adeno-carcinoma of colon without lymphatic spread were observed ultrastructttrally under a transmission electron microscope. The results showed that the nuclei in ER-and PR-positive ceiis were darker than those in negative cells and the autochromatin increased markly presented as fine granules.Most nucleolus were consisted of fine granulars.However,in the ER-and PR-negative cells, a characteristic finding was that there were much more free ribosomes in the cytoplasm.The results suggest that there may be differences in the mati-bolic type between ER-and PR-positive and negative cancer cells.
Keywords:Cancer Digestive tract ER PR Ultrastructure
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