| 冠心病患者及健康人血浆脂蛋白(a)水平 |
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| 引用本文： | 闫智宏,张动,梁庆智.冠心病患者及健康人血浆脂蛋白(a)水平[J].河北北方学院学报(医学版),1996(1). |
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| 作者姓名： | 闫智宏 张动 梁庆智 |
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| 作者单位： | 张家口医学院生物化学教研室
(闫智宏，张动)，张家口市第一医院急诊科(梁庆智) |
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| 摘 要： | 本文以酶联免疫吸附法(ELISA)测定了54例不同类型及不同并发症的冠心病患者与30名健康人的血浆Lp(a)浓度 心肌梗塞组和心绞痛组的Lp(a)浓度均高于对照组,并发糖尿病组Lp(a)浓度显著高于其他各组,无并发症且年龄较轻者Lp(a)浓度显著高于年龄较高者,表明血浆高Lp(a)水平是冠心病的遗传危险因素,但其升高的程度不能反映冠心病的临床类型或严重程度;并发糖尿病是老年冠心病患者血浆Lp(a)浓度升高的原因之一。
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| 关 键 词： | 脂蛋白(a) ELISA法 冠心病 |
PLASMA LIPOPROTEIN (A) LEVELS IN PATIENTS WITH CORONARY HEART DISEASE AND HEALTHY MEN AND WOMEN |
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| Yan Zhihong et al.PLASMA LIPOPROTEIN (A) LEVELS IN PATIENTS WITH CORONARY HEART DISEASE AND HEALTHY MEN AND WOMEN[J].Journal of Hebei North University:Medical Edition,1996(1). |
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| Authors: | Yan Zhihong |
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| Institution: | Yan Zhihong et al |
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| Abstract: | Plasma Lp (a) Ievels were determmed by cnzymclinked immunodorbe.nl assay m 54 pa-tients with different types and complications of CHD and m 30 healthy people. Plasma 1-p (a) concentra-tions in both the myocardial infarction group and the angina pectoris group were sigmficantly higher than m control group. Lp (a) concentrations m CIID with diabefes mellitus group were significantly higher fhan mthe other groups. Lp (a) concentrations with CHD without complication (age;-a,45 yaer - old subgroup) were sigmficantly higher than m the other groups. It suggests that Lp (a) is a genitic nsk factor for CHD and the extenf of increase in Lp (a) concentration can not reflect the rlmical types and the seventy of CHD. Diabetes mellitus complication may be one of the cause for the increase of Lp (a) concentration in elder patients with CHD. |
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| Keywords: | Lipoprotein (a) Enzyme- linked immunosorbent assay Coronary heart disease |
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