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1.
癌症的发生主要是因自然界六淫,精神方面的七情,饮食方面的五味,劳逸的失度,先后天三元比例失调而引起,与人的不良行为和心理因素有着密切联系。元极医学可通过改善病人的不良情绪,消除病人的不良行为,使患者从绝望、焦虑、恐惧中解脱出来,提高机体免疫力,并通过三元能量的作用达到防治癌症的目的。 相似文献
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D. Krishnaveni Amar Chand Bhayal K. Sri Manjari A. Vidyasagar M. Uma Devi M. Ramanna A. Jyothy Pratibha Nallari A. Venkateshwari 《Indian journal of clinical biochemistry : IJCB》2012,27(3):259-264
Matrix metalloproteinase-9 (gelatinase B) plays a key role in cancer invasion and metastasis by degrading the extracellular matrix and basement membrane barriers. A cytosine (C) > thymidine (T) single nucleotide polymorphism (SNP) at position −1562 in the MMP-9 promoter is reported to influence the expression of the gene. Genotyping of MMP-9 −1562 C→T promoter polymorphism in 140 gastric cancer patients and 132 healthy control subjects was carried out in order to evaluate its association with progression and development of gastric cancer. The SNP was genotyped by tetra-primer amplification refractory mutation system-polymerase chain reaction followed by agarose gel electrophoresis. Statistical methods were adopted to test for the significance of the results. Risk factor profile of the patients revealed age above 50 years, smoking, alcoholism as the factors associated with the disease. The distribution of genotype frequencies in gastric cancer patients were 28.7 % of CC, 45.5 % of CT and 25.7 % of TT, whereas in control subjects 31.8 % of CC, 53.03 % of CT and 15.15 % of TT, respectively. The allelic frequencies were 51.51 % of C and 48.48 % of T in patient group and 58.33 % of C and 41.66 % of T in controls respectively. The present study shows the possible association of epidemiological risk factors with gastric cancer. There is an increased frequency of T allele in the disease compared to control subjects. However, there is no association of the MMP-9 −1562 C→T promoter polymorphism in the development of gastric cancer. 相似文献
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Girija Ramaswamy Vasanti R. Rao Lakshmi Krishnamoorthy G. Ramesh R. Gomathy D. Renukadevi 《Indian journal of clinical biochemistry : IJCB》2000,15(2):110-113
BALP activity in the sera of metastatic patients of breast and prostate malignancy has increased significantly. Our studies
with patients in India conform the earlier reports that BALP may have a useful complementary role in the early diagnosis of
bone metastases. 相似文献
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本文是运用合理情绪疗法成功咨询一例考试焦虑问题的个案。该案例的求助者因考试焦虑主动前来咨询。经过搜集、整理求助者的相关资料,与求助者协商,制定咨询目标及方案。咨询中使用合理情绪疗法,帮助求助者识别不合理信念,代之以合理信念,取得了较好的咨询效果。 相似文献
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Amitabha Ray Anil Kumar Bahadur S. L. Dayalu Naik Bhuvnesh Kumar Sharma 《Indian journal of clinical biochemistry : IJCB》2001,16(2):199-202
Endogenous oestrogens are thought to be involved in breast cancer, but few studies could show the direct relationship between
hormones and pathological process of the disease. In the present study, oestradiol was estimated in the serum of pre-and postmenopausal
breast cancer patients along with normal healthy controls and patients with carcinoma of the uterine cervix which is not dependent
on oestrogens. Premenopausal patients with breast cancer showed higher levels of oestradiol as compared to premenopausal control
women as well as cervical cancer patients. Whereas, no statistically significant differences were observed in serum oestradiol
levels amongst postmenopausal groups of breast cancer, cervical cancer and normal women. The result of the study reflects
the association of oestradiol as well as its difference in the pathological events of pre and postmenopausal breast cancer. 相似文献
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Keith Bauer 《Ethics and Information Technology》2004,6(2):83-91
Some critiques of cybermedicine claim that it is problematic because it fails to create physician–patient relationships. But, electronically mediated encounters do create such relationships. The issue is the nature and quality of those relationships and whether they are conducive to good patient care and meet the ethical ideals and standards of medicine. In this paper, I argue that effective communication and compassion are, in most cases, necessary for the establishment of trusting and morally appropriate physician–patient relationships. The creation of these relationships requires patients and physicians to take psychological and emotional risks and to make commitments to each other. The problem is that by altering the form and content of verbal and non-verbal behaviors and by limiting the kinds of interactions that can take place, cybermedicine makes risk-free interactions easier and more commonplace and retards the development of physician compassion and patient trust. In doing so, cybermedicine encourages morally inappropriate physician–patient relationships. I argue that Merleau-Ponty's notion of embodiment and Kierkegaard's criticisms of disinterested reflection help us to understand how cybermedicine can undermine patient health and well being and why it should be seen as a possible threat to the moral integrity of physician–patient relationships. 相似文献
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SRB显色法用于抗癌药物敏感性试验的研究 总被引：13，自引：0，他引：13
采用ＳＲＢ显色法对９６孔培养板中短期培养的人大肠癌细胞株Ｃｏｌｏ２０５、人骨肉瘤细胞株ＯＳ７３２,人舌癌细胞株Ｔｃａ８１１３经５－ＦＵ,顺铂,蟾酥等药物处理后的活性进行了研究。结果表明,ＳＲＢ法对这些细胞株的体外抗癌药物敏感试验结果稳定,该法与其它细胞毒试验相比有一定优点,值得推广应用。 相似文献
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Sharmila Upadhya Subramanya Upadhya D. M. Vasudevan 《Indian journal of clinical biochemistry : IJCB》2003,18(1):46-51
The study was designed to evaluate the significance of tissue polypeptide specific antigen (TPS) in patients with histologically
proven ovarian and colorectal cancer following treatment along with CA125 (in ovarian cancer) and CEA (in colorectal cancer).
Patients were grouped as follows:
In patients with ovarian and colorectal cancer, the mean TPS levels were significantly higher in patients of group II compared
to group I. The percentage of patients above cut-off levels for TPS were 17.4% in group I and 95.5% in group II. Similar results
were observed with the mean levels of CA125. In colorectal cancer patients, the percentage of patients above cut-off levels
for CEA and TPS were 70% and 30% in group I and 100% in group II for both the markers. Our observations indicate that TPS
may be used as a common marker to indicate metastases in patients with ovarian and colorectal cancer. 相似文献
| Group I | : Patients with stable disease |
| Group II | : Patients with metastasis and relapse |
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本文是运用合理情绪疗法成功咨询一例考试焦虑问题的个案。该案例的求助者因考试焦虑主动前来咨询。经过搜集、整理求助者的相关资料,与求助者协商,制定咨询目标及方案。咨询中使用合理情绪疗法,帮助求助者识别不合理信念,代之以合理信念,取得了较好的咨询效果。 相似文献
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《Journal of The Franklin Institute》2006,343(4-5):329-339
A fuzzy logic-based model is used for generating an index which reflects the harmony of nasal proportions of a rhinoplasty patient. The index generated by the model is intended to be used as an objective tool for evaluating the harmony of nasal proportions of the patient. One of the possible uses of the index is to rate the nasal proportions of the patient relative to an ideal nose. Another possible use of the index is to generate a score for the patient before and after the rhinoplasty operation so that the improvement due to rhinoplasty operation can be determined objectively. 相似文献
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D. Jain A. Ray A. K. Bahadur K. U. Chaturvedi R. Sood S. Sharma S. L. D. Naik B. K. Sharma 《Indian journal of clinical biochemistry : IJCB》2001,16(1):42-51
There are numerous growing evidences of resemblance between carcinomas of the breast and prostate. A total of 45 cases of
these two hormone-dependent cancers along with appropriate controls were subjected for status of epidermal growth factor receptors
as well as serum lipid profile. Paraffin embedded tissue sections from aforesald tumours were analysed by immunohistochemical
staining for epidermal growth factor receptor (EGF-R), c-erbB-2 oncoprotein, estrogen receptor (ER) and progesterone receptor
(PgR). Sera from same individuals were studied for serum lipid profile analysis. The study revealed that immunoexpression
of all receptor proteins (EGF-R). c-erbB-2 was significantly higher in breast carcinoma. In addition, mean levels of triglycerides,
total cholesterol, LDL-cholesterol were found to be significantly elevated while the level of HDL-cholesterol was observed
to be lower among patients with breast cancer as compared to matched controls. Further, ER-positive breast cancer cases have
significantly higher mean level of HDL-cholesterol when compared with ER-negative breast cancer patients. Contrary to this,
no alteration in different serum lipid fractions was noticed among the patients with prostate cancer. However, a positive
relationship was noticed between immunoexpressions of EGF-R and c-erbB-2 in prostate cancer. 相似文献
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本文综合美国主要癌症基金过去7年中对癌症项目的资助情况,从项目的领域分布、项目的数量变化、项目的类型分布、癌症种类情况等多个角度,分析美国癌症基金的资助现状和特点,对了解和把握国外癌症研究方向有借鉴意义,同时为我国癌症基金工作提供有益思路。 相似文献
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Atanu Kumar Dutta 《Indian journal of clinical biochemistry : IJCB》2012,27(2):200-201
A 60-year-old patient suffering from easy fatigability was noted to have high total but normal conjugated bilirubin level though serum colour was pale. On further investigation the patient was found to be suffering from multiple myeloma and gamma globulin was possibly interfering with total bilirubin estimation. 相似文献
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目的:探讨标准化病人教学法在护理本科生社区护理学实践教学中的应用效果。方法:采用立意抽样法,选取12名参加社区护理学标准化病人实践教学的本科护生进行半结构化访谈,用Colaizzi七步分析法对访谈资料进行分析并提炼主题。结果:在社区护理学实践教学中实施标准化病人教学法,可以提高学生参与实践学习的积极性,促进系统化临床思维形成,树立正确职业价值观,培养应变、沟通、团队合作能力等护理软技能,但也存在改进的空间。结论:在社区护理学实践教学中实施标准化病人教学法有助于培养应用型社区护理人才,但在引导学生适应教学方法转变、完善教学条件、提升教师教学能力、合理公正地评价等方面,仍须在实践中进一步完善。 相似文献
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Cristiano Ialongo Sergio Bernardini 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2016,26(1):17-33
The evidence-based paradigm has changed and evolved medical practice. Phlebotomy, which dates back to the age of ancient Greece, has gained experience through the evolution of medicine becoming a fundamental diagnostic tool. Nowadays it connects the patient with the clinical laboratory dimension building up a bridge. However, more often there is a gap between laboratory and phlebotomist that causes misunderstandings and burdens on patient safety. Therefore, the scope of this review is delivering a view of modern phlebotomy to “bridge” patient and laboratory. In this regard the paper describes devices, tools and procedures in the light of the most recent scientific findings, also discussing their impact on both quality of blood testing and patient safety. It also addresses the issues concerning medical aspect of venipuncture, like the practical approach to the superficial veins anatomy, as well as the management of the patient’s compliance with the blood draw. Thereby, the clinical, technical and practical issues are treated with the same relevance throughout the entire paper.Key words: phlebotomy, venipuncture, laboratory testing, preanalytical phase, preanalytical variability, patient safety, evidence based medicine 相似文献
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通过运用森田疗法和艾利斯合理情绪疗法,对一例社交恐怖症患者进行了咨询。通过咨询,求助者的社会交往障碍得到基本的控制,基本达到了咨询的效果。经过这次咨询,证明森田疗法和艾利斯合理情绪疗法对社交恐怖症进行咨询和治疗是有效的。 相似文献
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抑郁症是一种常见的精神疾病,主要表现为情绪低落,兴趣降低,思维迟缓,缺乏主动性,自责自罪,饮食、睡眠差,担心自己身患疾病,感到全身多处不适,严重者可出现自杀念头和行为,患者无自知力。在本案例中求助者由于成长环境、负性生活事件、性格内向以及缺少社会支持系统的帮助而出现了抑郁症。该求助者无幻觉、妄想等症状、没有主动求治的愿望,因此排除了精神分裂症、抑郁性神经症等。针对本案例的具体情况,主要采用认知疗法,运用社会支持系统改变其不良的认知模式,消除自卑心理,重塑自信,使抑郁情绪得到释放和缓解,逐步走出抑郁。 相似文献
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人际交往障碍往往是影响人成才的重要因素,而这种情况在大学生中更是普遍。对于人际交往障碍来访者,运用认知疗法、合理情绪疗法等来改变求助者的不合理看法和认知,从而引导求助者消除人际交往障碍心理,重新树立人际交往的自信心。 相似文献