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1.
冠心病是严重危害人类健康的主要疾病,经皮冠状动脉介入法已经在国内广泛应用于临床治疗冠状动脉粥样硬化,成为目前治疗冠心病的主要方法之一。经桡动脉介入治疗应运而生,因其损伤小、局部并发症少,手术前后对抗凝、抗血小板药物限制小,术后立即拔管,患者即可随意下地活动而越来越受到患者和介入医生的欢迎。虽然大多数文献报道经桡动脉介入治疗的并发症明显低于经股动脉介入治疗。但由于桡动脉途径自身的生理特点及局限性,并发症也并不少见,如处理不当,有时会导致严重的后果,因此,在经桡动脉行冠状动脉介入手术时应注意观察及护理。  相似文献   

2.
目的:比较经桡动脉和经股动脉介入治疗冠心病的临床疗效和优势.方法:收集2009年10月至2012年3月于我院接受冠心病介入手术治疗的78例患者,其中48例患者接受经桡动脉介入手术(为经桡动脉组),30例患者接受经股动脉介入手术(为经股动脉组),比较两种术式患者的平均穿刺时间、术中动脉痉挛发生率、手术成功率及术后并发症.结果:经桡动脉组患者平均穿刺时间较经股动脉组时间长(P<0.05),且术中动脉痉挛发生率较经股动脉组高(P<0.01),两组手术成功率无显著性差异(P>0.05),但经桡动脉组的术后并发症远低于经股动脉组(P<0.01).结论:经桡动脉介入手术治疗冠心病创伤小、并发症少、住院时间短,是一种安全可行的介入术式,值得临床推广和应用.  相似文献   

3.
目的:探讨国人血浆脂蛋白相关磷脂酶A2(Lp-PLA2)活性与急性冠脉综合征(ACS)不同临床类型以及冠脉病变严重程度之间的关系.方法:对80例疑诊为ACS的患者行冠状动脉造影,按造影结果分为冠心组和正常对照组,再以冠心病临床类型、冠脉病变支数、Gensini积分将冠心病组患者分成不同的亚组,用统计学方法比较各组之间Lp-PLA2水平的不同.结果:不稳定型心绞痛组和心肌梗死组Lp-PLA2活性均显著高于正常对照组(P<0.05).Lp-PLA2活性随着冠脉病变支数和Gensini积分的增加而升高.结论:Lp-PLA2活性能反应冠脉病变的稳定性,与冠脉病变严重程度有关.  相似文献   

4.
目的:探讨妇产科手术后并发膀胱阴道瘘的诊断及处理方法。方法:对27例妇产科手术后并发膀胱阴道瘘患者经膀胱镜检查和膀胱亚甲蓝试验确诊;1例经停留导尿管后自行闭合,26例于损伤发生后3~5个月行膀胱阴道瘘修补术,其中9例经阴道途径,经膀胱途径17例。结果:26例手术均获得成功,随访0.5年均无复发。结论:对膀胱阴道瘘的手术治疗应根据患者的一般情况、瘘管性质及手术者的经验来选择手术时机和手术途径。  相似文献   

5.
目的:进一步探讨经桡动脉局部溶栓在组织移植术后动脉危象中的治疗效果。方法:对930例断指再植和足趾再造手指术后出现动脉危象的106例患指,经桡动脉进行动脉内溶栓治疗。结果:106例动脉危象患指经动脉内溶栓治疗成功91例,失败15例。结论:动脉内溶栓是移植组织动脉危象的一种较好的治疗方法。早期预置溶栓装置并预防性用药能够减少危象发生率,提高移植成功率。  相似文献   

6.
88例子宫肌瘤手术的临床分析   总被引:1,自引:0,他引:1  
目的:探讨子宫肌瘤的临床特点和手术方式的选择.方法:对88例子宫肌瘤行手术治疗并经病理证实的病例资料进行回顾性分析.其中全子宫切除术48例,次全子宫切除术22例,子宫肌瘤剔除术18例.结果:88例子宫肌瘤经不同手术方式治疗,全部治愈,术后并发症少,无复发病例.结论:依据患者年龄、生育要求、肌瘤类型及合并卵巢肿瘤等具体情况,分别采取相应的手术方式均能达到良好的治疗效果,同时原则上因尽量保留卵巢.  相似文献   

7.
探讨急性冠脉综合症患者早期进行康复活动有助于减少因长期卧床引起的并发症,有利于患者的心理健康恢复。方法:对22例60岁以上未行PCI(经过冠脉介入)或CABG(冠状劲脉旁路术)等冠脉血运重建术的老年ACS患者早期康复活动及出院后的临床观察。结果:老年ACS患者在参加早期康复活动后,无一例患者出现长期卧床后易出现的并发症。结论:对未行血运重建的ACS患者(包括老年患者),推行早期康复活动方案及早期出院,可减轻患者及家属的经济及精神负担,促进ACS患者的早日康复,增加医疗单位病床利用率,降低总医疗费用。  相似文献   

8.
目的:评估胸痛结合心电图ST-T改变在确认冠心病方面的价值,为临床治疗提供简单有效的方法.方法:选取2009年1月至2011年1月我院收治的86例心电图ST-T改变患者为研究对象,根据患者有无胸痛将其随即分为对照A组和对照B组,两组患者均行冠脉造影.对比两组患者的冠脉造影结果,并做统计学分析.结果:对照A组患者的冠脉造影阳性率83%,对照B组患者的冠脉造影阳性率为21%,两者相比有明显的差异,具有统计学意义(P?0.05).结论:胸痛结合心电图ST-T改变在确认冠心病临床价值较高,仅凭心电图ST-T改变不能确诊患者冠心病.  相似文献   

9.
目的:初步探讨吸烟冠心病病人的冠脉造影血管形态和血流特点.方法:2004年3月至2014年7月就诊于赤峰学院附属医院心内科,行冠脉造影确诊为冠心病的524例病人.吸烟组243例(男114例,女29例),年龄39~76岁,平均(53.53±9.35)岁,吸烟年限5~52年,平均(29.35±8.38)年.同期选取不吸烟的患者281例(男149例,女32例)年龄42~79岁,平均(54.78±8.63)岁,作为对照组.比较两组间冠脉造影的冠脉形态和血流特点的差异.结果:吸烟组与对照组在冠脉瘤样扩张和PTCA相关的冠脉慢血流发生率差异显著,吸烟组35例(14.4%)有冠脉瘤样扩张;对照组6例(2.1%)(P<0.001);吸烟组有53例(21.8%)有PTCA相关冠脉慢血流现象,对照组有7例(2.5%)(P<0.001).结论:吸烟患者冠脉瘤样扩张较多发,且PTCA相关冠脉慢血流现象的发生率较高.  相似文献   

10.
49例心肌桥-壁冠状动脉造影特点及临床意义   总被引:1,自引:0,他引:1  
目的:探讨心肌桥-壁冠状动脉(MB-MCA)的造影及临床特点.方法:回顾分析923例接受选择性冠脉造影患者,特别对其中49例MB-MCA患者造影及临床特点进行分析.结果:49例MB-MCA患者中40例单发肌桥,9例复发肌桥.其中MB-MCA合并冠脉粥样硬化8例,肌桥前7例,肌桥后1例.结论:造影时,MB-MCA以左肩位、头位、右肩位收缩期狭窄表现最严重,MB-MCA虽多为良性过程,非冠脉粥样硬化独立诱发因素,但也可以引起心肌缺血.  相似文献   

11.
目的:探讨小儿重型颅脑损伤的临床诊断及治疗特点。方法:对66例小儿重型颅脑损伤的临床资料进行回顾性总结。结果:闭合性颅脑损伤59例,重残3例,死亡8例。结论:小儿重型颅脑损伤临床表现是复杂的,但死亡率低,较成年人恢复快,预后好。  相似文献   

12.
AMI患者PCI术对血浆BNP水平变化的初步临床观察   总被引:1,自引:0,他引:1  
目的:观察PCI术对AMI患者血浆中BNP的水平变化,初步探讨PCI对AMI患者预后的影响.方法:采用快速荧光免疫测定法对20例AMI患者PCI治疗前后和20例对照组血浆BNP水平进行检测.结果:AMI患者血浆BNP在AMI患者PCI术与对照组比较有显著性差异(P<0.05),PCI治疗后呈明显下降趋势.结论:AMI患者PCI治疗血浆BNP水平变化说明PCI术能对改善AMI患者的预后有重要意义.  相似文献   

13.
目的:探讨腹腔镜胆囊切除术胆管损伤的原因及预防方法.方法:2002.7~2004.12月间在我院施行腹腔镜胆囊切除术的病人共623例,其中胆管损伤3例,结合临床资料,分析其损伤原因.结果:胆囊切除术胆管损伤的主要原因为术者技术操作原因及胆囊周围局部不良因素.结论:提高术者技术操作水平及正确的操作过程对预防腹腔镜胆囊切除术胆管损伤有重要作用.  相似文献   

14.
Objective: The beneficial effect of percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI) has been well established, but there is the problem of no-reflow phenomenon which is an adverse prognostic factor in primary PCI. In the present study the effect of a distal protection device (PercuSurge GuardWire; GW) on epicardial blood flow and myocardial perfusion was evaluated. Methods and Results: Patients with AMI were randomly divided into 2 groups, the GW and the control groups. The GW group included 52 patients with AMI who underwent primary PCI with GW protection and the control group included 60 patients who underwent primary PCI without GW protection. Epicardial blood flow in the infarct-related artery (IRA) and myocardial perfusion were evaluated according to the thrombolysis in myocardial infarction (TIMI) flow grade and the myocardial blush grade (MBG). We found TIMI score of 3 was obtained significantly more frequently in the GW group (96%) than in the control group (80%). The MBG score of 3 was obtained also significantly greater in the GW group (65%) than in the control group (33%). Conclusion: Primary PCI with GW protection can significantly improve epicardial blood flow and myocardial perfusion.  相似文献   

15.
Objective:Percutaneous coronary intervention(PCI) triggers an acute inflammatory response,while sirolimus is known to have anti-inflammatory properties;the inflammatory system response to PCI after sirolimus-eluting stent placement remains unclear.The purpose of this study is to determine the changes in high sensitive C-reactive protein(hs-CRP) and apelin after PCI procedure and drug-eluting stent implantation in patients with and without reduced left ventricular systolic function.Methods:Forty-eight consecutive patients undergoing PCI at the Beijing Anzhen Hospital between July and September 2006 were recruited.Sirolimus-eluting stents were employed in all patients.Blood samples were drawn immediately before and 24 h after the procedure.Plasma hs-CRP and apelin levels were determined by enzyme immunoassay.Results:Paired t-test revealed a significant increase in both hs-CRP and apelin post-procedure(P=0.006 and P0.0001,respectively).Patients with reduced left ventricular ejection fraction(LVEF) had significantly lower baseline apelin levels compared to those with normal ventricular function [(46.8±10.8) vs.(72.0±8.4) pg/ml,P0.001].However,apelin increased to a level similar to the level of those with normal left ventricular systolic function 24 h after the PCI procedure [(86.7±11.6) vs.(85.1±6.1) pg/ml,P=0.72].Conclusions:hs-CRP and apelin levels increased after PCI and sirolimus-eluting stent implantation.Patients with impaired left ventricular systolic function had significantly lower baseline apelin levels,which increased significantly after PCI.  相似文献   

16.
目的:探讨腹腔镜手术在妇科手术中的应用和治疗效果.方法:对23例卵巢良性肿瘤患者,实行了腹腔镜下肿瘤囊壁剥除术,保留了卵巢;对3例多囊卵巢行打孔术;对9例异位妊娠患者,6例行患侧输卵管切除术,3例行保守手术.结果:35例患者手术均成功,无1例中转开腹,无1例出现并发症,近期随访无复发.异位妊娠保守手术者均于术后二周复查血HCG为阴性,无持续妊娠,无术后出血.结论:腹腔镜手术具有损伤小,恢复快,并发症少,治疗效果可靠及住院时间短等优点.尤其附件良性病变是腹腔镜手术的最佳适应证,值得有条件的医院推广应用.  相似文献   

17.
Objective:This study aims to determine the mechanisms underlying restenosis and ischemia-reperfusion injury of the myocardium after percutaneous coronary intervention (PCI).Methods:The present study examined serial changes (5 min,30 min,2 h,6 h,and 24 h after PCI) in circulating P-selectin,plasminogen activator inhibitor-1 (PAI-1),magnesium (Mg),and creatine kinase-myocardial band fraction (CK-MB) levels,which may be associated with restenosis and myocardial injury in patients undergoing PCI.The occurrence rates of major adverse cardiovascular events were collected over a six-month follow-up.Results:PCI induced an early elevation of P-selectin,which correlated positively with the inflation pressure used in the PCI procedure.PCI also caused a significant and sustained decrease in serum Mg in PCI patients,without an effect on PAI-1.An increase in CK-MB was observed in PCI patients,although values were within normal reference range.In addition,elevated P-selectin and decreased Mg measured shortly after the coronary angioplasty procedure were associated with recurrent treatment and heart failure,respectively.Conclusions:Our study demonstrates that PCI induces temporal changes of P-selectin,Mg,and CK-MB,which may be involved in restenosis and ischemia-reperfusion injury.These findings highlight the need for using antiplatelet therapy and Mg to reduce the risks associated with PCI.  相似文献   

18.
AMI患者PCI术后BNP相关分析及应用研究   总被引:2,自引:0,他引:2  
目的:观察PCI术对AMI患者血浆中BNP的水平变化,探讨PCI对AMI患者预后的影响.方法:采用快速荧光免疫测定法对50例AMI患者PCI治疗前、治疗后7d内每日同一时间取静脉血进行BNP的测定和50例对照组血浆BNP水平进行检测.结果:AMI患者血浆BNP在行PCI术后与对照组比较有显著性差异(P<0.05),PCI治疗后呈明显下降趋势.结论:AMI患者经PCI治疗血浆BNP水平变化说明PCI术对改善AMI患者的预后有重要意义.  相似文献   

19.
Objective:The aim of this study is to investigate if dual-source computed tomography(DSCT) could guide the percutaneous coronary intervention(PCI) of chronic total occlusion(CTO).Methods:We enrolled patients who were confirmed to have at least one native coronary artery CTO by DSCT before they underwent selective PCI in the period from December 2007 to October 2008.A CTO was defined as an obstruction of a native coronary artery with no luminal continuity.The CT-guided PCI procedure involved placing CT and fluoroscopic images side-by-side on the screen.DSCT images were analyzed for location,segment,plaque characteristics,calcification,and proximal lumen diameter of the CTO before PCI.The guidewire was advanced and manipulated under CT guidance.The PCI was carried out and the results were compared.Results:Seventy-four CTOs were assessed.PCI was successful in 57 cases of CTOs(77.0%).According to the results,CTOs were divided into two groups:successful-PCI and failed-PCI.All coronary artery paths of CTOs were clearly recognized by DSCT.In the successful-PCI group,soft plaques were detected much more often than those in the failed-PCI group,but fibrous and calcified plaques were seen more often in the failed-PCI group.Calcification severity in CTO segments showed a significant difference between the groups(P=0.014).Calcified plaques were detected in 20(35.1%) lesions in the successful-PCI group.More than 70% of the failures were calcified plaques,of which there were two arc-calcified and one circular-calcified lesions.Occlusions were longer in the failed-PCI group than those in the successful-PCI group [(38.8±25.0) vs.(18.0±15.3) mm,respectively,P0.01].Fewer guidewires were used in the successful-PCI group compared with the failed-PCI group(1.7±1.0 vs.2.5±0.9,respectively,P0.01).The logistic regression analysis indicated that predictors of recanalization of CTOs included occlusion length(P=0.0035,risk ratio(RR)=0.93) and calcification severity(P=0.05,RR=0.27).Multi-linear trends analysis showed that the factors affecting procedural time were CTO location(P=0.0141) and occlusion length(P=0.0035).Conclusions:DSCT could delineate the path of CTOs and characterize plaques.The outcomes of PCI were related to thrombolysis in myocardial infarction(TIMI) flow grade,CTO characteristics,severity of calcified plaques,and the length of occlusive segments.Occlusion length and calcification severity were independent predictors of CTOs.Occlusion length and CTO segments could also help to estimate the duration of interventional procedures.  相似文献   

20.
研究了用物理掺杂、化学镀、包覆等三种方式饰钴后的镍电极的性能.通过比较充放电曲线、循环伏安以及扫描电镜测试结果发现:以包覆钴形式对镍电极进行修饰的效果较好.  相似文献   

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