共查询到20条相似文献，搜索用时 265 毫秒
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目的探讨局部灌注热疗和常规介入栓塞化疗相结合治疗中晚期肝癌的疗效.方法 60例中晚期原发性肝癌患者随意分为两组,治疗组病例局部灌注热疗和常规介入栓塞化疗,共30例;对照组病例单纯介入栓塞化疗,共30例.结果治疗组有效率为8 3.33%;对照组有效率为66.67%,两组比较有显著性差异(P＜0.05);全部患者治疗后随访,治疗组中位生存期为11.6个月,1年生存率为46.7%,对照组中位生存期为8.3个月,1年生存率为26.7%,两组比较差异性显著(P＜0.05).结论加热联合介入栓塞化疗对原发性肝癌具有较好的治疗作用,局部热疗加介入栓塞化疗比单纯介入栓塞化疗治疗中晚期原发性肝癌放果更好. 相似文献
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肢体的恶性肿瘤治疗,通常以截肢为主要治疗手段,随着近年来加大术前、术后辅以化疗、放疗、免疫疗法及综合治疗,使术后５年成活率提高到１０％～３０％。选择性动脉灌注、栓塞用于骨肿瘤的治疗是近１０～２０年发展起来的一项新技术、新方法。它不仅可以减少术中出血,... 相似文献
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目的 观察诺迪康胶囊治疗椎基底动脉供血不足的疗效。方法将椎基底动脉供血不足患者60例随机分为诺迪康治疗组（30例）和对照组（30例）,两组采用相同的综合治疗方法,均采用香丹注射液10ml,加入5％葡萄糖或0．9％氯化钠500ml中静脉滴注,每日1次;治疗组加用诺迪康胶囊每次2粒,每日3次,口服;疗程约4周。对两组疗效进行对比分析,并观察,治疗组治疗前后经颅多普勒检查变化情况。结果①治疗组总有效28例,总有效率为93％。对照组总有效25例,总有效率83％。两组总有效率比较差异有显著性（P〈0．05）。②治疗组治疗前后比较椎基底动脉平均血流速度的变化差异亦具有显著性（P〈0．05）。结论诺迪康胶囊能改善脑供血,并显著增加脑血流量;说明诺迪康胶囊治疗椎基底动脉供血不足安全而有效。 相似文献
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目的:探讨支气管动脉内化疗药物灌注(BAI)治疗中晚期肺癌的临床效果。方法:对临床确诊为中晚期肺癌的88例病人进行支气管动脉内化疗灌注(BAI),化疗药物组合依据不同的病理类型选择不同的化疗药物。结果:本组病例完全缓解(CR)17例(19.3%),部分缓解(PR)52例(59.1%),稳定(S)15例(17%),进展4例(4.5%),本组病例显效(CP PR)69例(78.4%)。有效(CP PR S)84例(95.5%)。结论:支气管动脉内灌注化疗药物(BAI)治疗中晚期肺癌疗效确切,近期疗效显著。BAI治疗中晚期肺癌病期愈早,效果愈好。化疗效果与临床病理类型无显著关系。化疗效果与肿瘤部位密切相关,中央型(90%)优于周围型(33%)(P<0.01)。化疗效果与肿瘤部位血管类型关系密切,多血管型肺癌的总缓解率(85.9%)优于少血管型(58.3%)(p<0.01)。 相似文献
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观察参麦减轻对恶性肿瘤的化疗后的毒副作用治疗效果.方法恶性肿瘤住院患者136例全身静脉化疗药物滴注后使用参麦注射液(杭州正大青春宝药业有限公司生产)60cc+5%,Gs500cc静脉滴注.1次/日,连用7天为1个疗程,每月2个疗程.对照组120例反给予全身化疗药物静脉滴注,化疗21天为1个周期.结果参麦组瘤灶完全消失16例(11.7%)瘤灶明显缩小68例(50%),瘤灶略缩小40例(29.4%),有效率(PR+CR)61.7%,稳定率(CR+PR+NC)91.1%,而对照组上述指标分别为4例(3.3%),32例(26.6%),24例(20%)有效率50%,两组比较差异显著,P值《0.01.结论麦注射液用于恶性肿瘤患者化疗后,能减毒增效、调节免役能力,提高患者生活质量. 相似文献
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５９例诊断为耳部化脓性感染的门诊病人按随机分组，双盲法给药，分别接受氟嗪酸滴耳剂和氯霉素眼液滴耳治疗，显效率分别为７１．１％和３８．１％，有显著差异（Ｐ＜０．０１），包括两名儿童在内的所有病人均示出现头晕、耳鸣、耳聋加重等副反应，２９例细菌学结果显示，氟嗪酸组细菌阴转率为９４．７％，远高于氯霉素组（５５．６％）。 相似文献
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目的评价扶正散结法中药辅助化疗治疗中晚期胃癌的疗效及安全性。方法通过检索数据库(The Cochrane Library,MEDLINE,EMBASE,CANCERLIT,CBM,CNKI,VIP等),查阅国内外重要学术会议论文汇编、中文类核心期刊等资料,将符合标准的扶正散结法中药(FZSJ)辅助化疗治疗中晚期胃癌的临床研究纳入本meta分析。使用RevMan 5.3软件进行Meta分析,采用Cochrane Handbook 5.3"偏倚风险评估"工具对文献质量进行评价。结果最终纳入20个随机对照研究,共计1735例患者。Meta分析结果显示:与单纯化疗比较,扶正散结法中药(FZSJ)辅助化疗可能提高患者近期有效率、1年及3年生存率、降低恶心呕吐及白细胞减少的毒副反应发生。结论扶正散结法中药辅助化疗治疗中晚期胃癌与单纯化疗比较,可能治疗效果更好,更安全,有一定的临床推广和运用价值。 相似文献
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肝癌介入治疗后并发症的处理 总被引：4，自引：0，他引：4
目的：探讨肝动脉化疗栓塞（TACE）治疗肝癌后的并发症及处理方法。方法：采用Seldinger技术经股动脉穿刺，将导管插至肝肿瘤供血动脉，进行一次性灌注化疗药物。结果：对68例肝癌患者进行了176次化疗栓塞，并发症有局部血肿、穿刺点出血、发热、肝区胀痛、肝脏的损害、胃肠道反应、骨髓抑制、肝性脑病、消化道出血等，只有1例因并发症死亡。结论：肝动脉化疗栓塞是治疗肝癌安全、有效的微创疗法，预防并发症，提高疗效。 相似文献
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Yixin Hu Aili Chen Xinchang Zheng Jun Lu Hailong He Jin Yang Ya Zhang Pinpin Sui Jingyi Yang Fuhong He Yi Wang Peifang Xiao Xin Liu Yinmei Zhou Deqing Pei Cheng Cheng Raul C Ribeiro Shaoyan Hu Qian-fei Wang 《国家科学评论(英文版)》2019,6(3):469
Standard chemotherapy regimens for remission induction of pediatric acute myeloid leukemia (AML) are associated with significant morbidity and mortality. We performed a cohort study to determine the impact of reducing the intensity of remission induction chemotherapy on the outcomes of selected children with AML treated with a low-dose induction regimen plus granulocyte colony stimulating factor (G-CSF) (low-dose chemotherapy (LDC)/G-CSF). Complete response (CR) after two induction courses was attained in 87.0% (40/46) of patients receiving LDC/G-CSF. Post-remission therapy was offered to all patients, and included standard consolidation and/or stem cell transplantation. During the study period, an additional 94 consecutive children with AML treated with standard chemotherapy (SDC) for induction (80/94 (85.1%) of the patients attained CR after induction II, P = 0.953) and post-remission. In this non-randomized study, there were no significant differences in 4-year event-free (67.4 vs. 70.7%; P = 0.99) and overall (70.3 vs. 74.6%, P = 0.69) survival in the LDC/G-CSF and SDC cohorts, respectively. After the first course of induction, recovery of white blood cell (WBC) and platelet counts were significantly faster in patients receiving LDC/G-CSF than in those receiving SDC (11.5 vs. 18.5 d for WBCs (P < 0.001); 15.5 vs. 22.0 d for platelets (P < 0.001)). To examine the quality of molecular response, targeted deep sequencing was performed. Of 137 mutations detected at diagnosis in 20 children who attained hematological CR after two courses of LDC/G-CSF (n = 9) or SDC (n = 11), all of the mutations were below the reference value (variant allelic frequency <2.5%) after two courses, irrespective of the treatment group. In conclusion, children with AML receiving LDC/G-CSF appear to have similar outcomes and mutation clearance levels, but significantly lower toxicity than those receiving SDC. Thus, LDC/G-CSF should be further evaluated as an effective alternative to remission induction in pediatric AML. 相似文献
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Hatice Saracoglu Gulden Baskol Mevlut Baskol 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2021,31(3)
We reported macrolipasemia in a colon cancer patient during the chemotherapy period without any evidence of pancreatitis. A 52-year-old man formerly treated for papillary thyroid carcinoma had elevated a carcinoembryonic antigen (CEA) concentration in the latest control and was diagnosed with colon cancer. Xelox chemotherapy (oxaliplatin and capecitabine) protocol was planned for six months. Interestingly, the lipase activities gradually increased from 30 U/L to 434 U/L, and exceeded three times the upper limit of the reference range (13-60 U/L). There were no symptoms of pancreatitis, and the abdominal computed tomography (CT) scan was also normal. Polyethylene glycol (PEG) recovery % values of serum samples gradually decreased and were 27% in the recent sample before the end of chemotherapy. Interestingly, the serum lipase activity fell a month after chemotherapy, and PEG recovery % increased (39%). We considered the following possibilities: (1) macrolipasemia due to chemotherapy drugs, (2) macrolipasemia due to antibodies against chemotherapy drugs. 相似文献
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目的研究诱导化疗,肿瘤细胞减灭术及术中高温胸腔灌注疗法对ⅣA期胸腺瘤的治疗效果。方法回顾性研究三年间在完成诱导化疗后行手术治疗的ⅣA期胸腺瘤患者的临床资料。结果没有院内死亡病例。中位随访时间为18.8个月（范围在1.5～31.9个月）。1名患者在术后14个月死于急性心血管意外。剩余存活的4名患者没有复发的证据。结论对于ⅣA期胸腺瘤来说,包括诱导化疗及肿瘤细胞减灭术的综合治疗是安全可行的,充分的胸膜部分切除术是胸膜外肺切除术（EPP）以外的又一选择。 相似文献
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观察补阳还五汤联合糖尿病治疗仪治疗糖尿病高危足的临床疗效。80例糖尿病足0级病变患者随机分为治疗组40例和对照组40例,在常规治疗的基础上,治疗组给予补阳还五汤联合糖尿病治疗仪治疗,对照组给予前列腺素E1治疗。疗程4周,评价疗效。结果：治疗组显效11例（27.5%）,有效23例（57.5%）,无效6例（15.0%）,总有效率85.0％;对照组显效2例（5.0%）,有效28例（70.0%）,无效10例（25.0%）,总有效率75.0％。治疗组显效率及总有效率优于对照组,差异有显著性意义（经Ridit检验,u=2.0430,P〈0.05）。补阳还五汤联合糖尿病治疗仪治疗糖尿病高危足疗效确切,值得临床推广应用。 相似文献
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目的 了解TP和CP治疗卵巢癌的效果。方法 回顾性分析我院2000年5月“2005年10月收治的40例卵巢癌病例资料。结果 两组疗效及生存率比较有显著性差异。（P〈0．05）。结论 以TAX为主的联合化疗方案对卵巢癌的疗效较好，尤其是对常规治疗后复发的患者。 相似文献
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Can serum Glutathione-S-transferase levels in carcinoma cervix be a predictor of radiation response?
Krishnananda Prabhu P. Gopalakrishna Bhat D. M. Vasudevan 《Indian journal of clinical biochemistry : IJCB》2005,20(1):95-97
We conducted a pilot study wherein serum Glutathione-S-transferase levels were measured before and after radiotherapy in carcinoma
cervix patients and correlated with response to treatment during a two-year follow-up period. Out of 17 patients who received
radiotherapy, 9 showed a significant decrease (p<0.005) while 8 showed significant increase (p<0.004) in post radiotherapy
glutathione-S-transferase values as compared to pre treatment values respectively. These patients were followed up for two
years and we observed that 71% who had significant increase in post radiotherapy values had relapse of cancer within 2 years
where as 66% of those who had significant decrease in post radiotherapy values had no evidence of relapse. This shows that
alterations in serum Glutathione-S-transferase levels may help us to predict radiation response 相似文献
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为研究膀胱刺激症的治疗,选择性对３８例膀胱刺激症患者进行了膀胱粘膜下注射利多卡因和地塞米松等药物治疗,并作疗效分析,结果膀胱刺激症各项症状有效率均在８２％以上,尿道综合征,前列腺炎和前列腺增生术后的膀胱刺激治疗有效率为８１．６％,表明膀胱粘膜下注射药物治疗膀胱刺激症的疗效令人满意,是一种适用于经口服药物或手术治疗无效患者的治疗方法。 相似文献
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通过１４例妇科肿瘤患者化疗后骨髓Ⅳ级抑制的护理,探讨在无隔离层流室的条件下医疗护理的信度和效度,经过护理人员的精心护理和医疗干预,除２例病情好转后放弃继续治疗外,１２例均痊愈出院,说明只要及早发现并对高危因素进行评估,采取积极的措施,化疗后骨髓Ⅳ级抑制是能得到控制和康复的。 相似文献
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目的:了解本科护理实习生人文关怀品质的现状并探讨其影响因素。方法:采用护士人文关怀品质量表对某三甲医院实习中后期的300名本科护理学生进行问卷调查,单因素用t检验分析,多因素选择多重线性回归分析。结果:回收有效问卷275份,有效回收率为94.8%。护理本科实习生人文关怀品质总分为(115.47±19.03)分;单因素分析显示,性别、选择护理专业的原因、科室的人文关怀氛围、是否接受过人文关怀相关培训等方面的得分差异具有统计学意义(P<0.05);多重线性回归分析显示,护理本科实习生选择护理专业的原因、科室的人文关怀氛围、是否接受过人文关怀相关培训是影响其人文关怀品质的重要因素(P<0.05)。结论:本科护理实习生的人文关怀品质还处于一般水平。选择护理专业的原因、科室的人文关怀氛围、是否接受过人文关怀相关培训等影响护理本科实习生的人文关怀品质。 相似文献
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肿瘤的治疗分为手术、放疗、化疗、生物治疗和中医中药治疗。中医中药治疗是肿瘤治疗的第五大手段,以其独特的学术理念和基于整体观的治疗方法为肿瘤患者,特别是已经失去手术机会的晚期恶性肿瘤患者提供了一种能改善生活质量、延长生存期的治疗手段;并对肿瘤的预防也起到一定的积极作用。 相似文献