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家蚕雌蛾体中微量元素和脂肪酸的分析 总被引：1，自引：0，他引：1
分析了家蚕雌蛾体中微量元素和脂肪酸的含量,并对其质量进行了评价.家蚕雌蛾体富含微量元素,检测的10种常见微量元素的加和量和人体必需宏量元素含量分别为27339.30 mg/kg和26900.00 mg/kg,其中人体需要量较大的4种微量元素(锌、铁、铜和锰)含量高于重要中药资源昆虫芫菁科昆虫蛾体中的含量.并且适合于人体日需要量.家蚕雌蛾体含有丰富的不饱和脂肪酸,其中必需的n-3系列多不饱和脂肪酸亚麻酸含量最高(39.88%),是鸡蛋的40倍和牛奶的38倍,并高于亚油酸含量6.5倍.研究结果显示,家蚕雌蛾是开发保健食品和医药品的优质原料. 相似文献
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环境激素壬基酚对家蚕生殖发育的影响 总被引：1，自引：0，他引：1
壬基酚(NP)是一种新确认的环境激素(EH)。为探讨EH对鳞翅目昆虫的性激素作用,用添加NP的人工饲料饲养家蚕,调查NP对生殖发育的影响。结果显示,刚孵化家蚕幼虫添毒72 h和120 h的LC50分别为1.1392、1.0695 mmol/kg。添毒NP1.000 mmol/kg以上浓度,家蚕在幼虫期死亡而不能完成世代。从生殖腺系数看,0.500 mmol/kg以下浓度的NP,对家蚕幼虫和蛹的睾丸生长无不良影响(P>0.05);大于0.250 mmol/kg的NP,能显著抑制雄蛾的睾丸生长(P<0.05);小于0.500 mmol/kg的NP,5龄幼虫和24 h龄蛹精细胞数量显著增加(P<0.05);高于0.125 mmol/kg的NP,168h龄蛹和24h龄蛾的精子数量显著少于对照(P<0.01)。高于0.125 mmol/kg的NP,5龄幼虫和蛹的卵细胞生长和发育被抑制(P<0.05),雌蛾造卵数和产出卵数减少(P<0.05),受精率降低(P<0.05)。NP通过抑制家蚕生殖腺的生长和生殖细胞的发育表现雌激素效应。 相似文献
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苯二氮卓类药物可缩短入睡时间、减少觉醒时间和次数、增加总睡眠时间,是目前使用最广泛的催眠药。苯二氮卓类药物具有使用安全、起效快、耐受性良好的特点。本文对合理使用苯二氮卓类药物治疗失眠症进行综述。 相似文献
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<正>失眠是指无法入睡或无法保持睡眠状态,导致睡眠不足。又称入睡和维持睡眠障碍(DlMS),为各种原因引起入睡困难、睡眠深度或频度过短、早醒及睡眠时间不足或质量差等,是一种常见病。失眠往往会给患者带来极大的痛苦和心理负担,又会因为滥用失眠药物而损伤身体其他方方面面。主要表现为睡眠时间深度的不足、以及不能消除疲劳、恢复体力与精力,轻者入睡困难,或寐而不酣,时寐时醒,或醒后不能再寐,重则彻夜不寐。在当下社会,人们由于就业困难、工作压 相似文献
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并非睡不着觉就是失眠,失眠是患者对睡眠的质（睡眠深度）和量（睡眠时间）的不满足,并影响白天社会功能的一种主观体验。其症状包括：入睡困难,就寝30分钟不能入睡;睡眠表浅,似睡非睡,早醒及醒后无法再入睡;梦多,每夜实际睡眠时间不足6小时;觉醒时间增多（每夜超过30分钟）：常被噩梦惊醒,睡醒之后仍感头昏、精神不振、嗜睡和疲乏无力等。 相似文献
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<正>随着现代生活节奏的加快,精神压力倍增,失眠的人数也越来越多,症状也越来越重,甚至有部分人群长期受失眠的困绕,给人们的生活、工作及健康带来了极大的影响。因此,这就需要我们对失眠有更多更充分的了解。失眠的症状失眠多数以下面三种形式呈现:第一种表现形式是晚上入睡困难,入睡时间延长,甚至躺下后常辗转反侧,直至凌晨才缓缓入睡;第二种表现形式是躺下后可以正常入睡,但保持睡眠的时间很短,睡后常出现凌晨容易醒,醒来以后就难以再次入睡,症状严重者甚至持续性地发生整晚无法入睡的情况; 相似文献
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分别以133、266、533mg/kg BW(分别相当于人体推荐用量的5、10、20倍)剂量的三抗牌氧宝红景天胶囊连续给小鼠灌胃30天,结果能够延长小鼠在亚硝酸钠中毒后的存活时间、延长小鼠在急性缺血性缺氧(断头)后张口喘气时间,具有延长小鼠因缺氧而死亡的时间,对小鼠的体重无影响,提示该产品具有提高缺氧耐受力功能. 相似文献
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采取小鼠游泳力竭并剥夺其睡眠时间的方法,使其在体力和精神上产生长期双重劳倦,以塑造出脾虚证模型;在造模过程中,每天测量其体重和体温的变化;用HE染色法,观察脾虚对肌纤维形态结构造成的影响。研究结果显示,脾虚小鼠一般健康状况下降;小鼠的体重减轻、体温下降;肌纤维形态发生变化,包括肌纤维变细、松散。 相似文献
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研究了显微镜检出蚕微粒子病的时期与微孢子虫感染剂量、感染蚕龄和所取样本的关系⒚结果表明,蚁蚕和２ 龄起蚕感染高剂量微孢子虫时,能在当龄镜检出孢子,感染低剂量微孢子虫时,可在次龄或以后镜检出孢子⒚从感染蚕中肠、粪便和蚕整体中镜检出孢子的时期,随微孢子虫感染剂量增大和感染蚕龄降低而提早,并且镜检出的时期从先到后分别为病蚕中肠、病蚕整体与病蚕粪便⒚本试验结果对于当前蚕微粒子病防治工作有积极的指导意义⒚ 相似文献
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Subbaiyan Thilagavathi Pachaiappan Pugalendhi Thangarasu Rajakumar Krishnamoorthy Vasudevan 《Indian journal of clinical biochemistry : IJCB》2018,33(4):387-396
Bisphenol-A (BPA) is a ubiquitous environmental chemical that produces adverse effect on reproduction system due to its potent estrogenic endocrine disruptive activity. The present study was aimed to investigate the monotonic dose effect of BPA on estrogen synthesis in female Sprague-Dawley rats. For this purpose, we administered three different doses of BPA (10, 50, 100 µg/kg bw/day) into rats and analyzed various biochemical, hormonal, molecular and histological parameters. 10 µg BPA treated rats showed significantly decreased levels of phase I detoxification agents (CYP450, Cyt-b5). Overexpression of eNOS with decreased expression of StAR and steroidogenic enzymes (CYP11A1, aromatase) indicate decreased production of estrogen. Increased levels of serum gonadotropins (FSH, LH) and decreased levels of estradiol suggest mimetic action of BPA and its feedback inhibition. Increased body weight, lipid profile status of 10 µg BPA treated rats and histological analysis of ovary and mammary tissue support the study. Overall, our results suggest that BPA exerts its estrogen mimetic effects in a monotonic manner. 相似文献
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本文通过问卷调查、数理统计、专家访谈、文献资料等研究方法,研究了辽宁工业大学在校女学生体育活动的情况,结果显示,女大学生从事体育活动的情绪不高,活动的时间、强度不足。造成这些现象的主要原因有体育场地设施不足、终身体育观念淡薄、缺乏有组织的体育指导以及在体育教学中对女大学生体育兴趣的培养不重视。针对这些问题,提出了一些增加女大学生从事体育活动的建议,希望能为女大学生体育活动的开展提供一些帮助。 相似文献
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Alcohol induced oxidative stress is linked to the metabolism of ethanol. In this study it has been observed that administration
of ethanol in lower concentration caused gain in body and liver weight. while higher concentration of ethanol caused lesser
gain in body and liver weight. Ethanol treatment enhanced lipid peroxidation significantly, depletion in levels of hepatic
glutathione and ascorbate, accompanied by a decline in the activities of glutathione peroxidase and glutathione reductase,
and increased in hepatic glutathione s-transferase activity. Interestingly catalase activity increases in lower concentration
of ethanol exposure, and decreased in higher concentration. Superoxide dismutase activity was also increased on ethanol exposure.
But, ethanol feeding did not show any effect on glucose-6-phosphate dehydrogenase activity. Ethanol ingestion perturbs the
antioxidant system in a dose and time dependent manner. 相似文献
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Ghizal Fatima Siddharth Kumar Das Abbas Ali Mahdi Nar Singh Verma Faizan Haider Khan Amit Mani Kumar Tiwari Tabrez Jafer Baby Anjum 《Indian journal of clinical biochemistry : IJCB》2013,28(2):181-184
Fibromyalgia syndrome (FMS) patients have disturbed sleep patterns which may lead to altered circadian rhythm in serum cortisol secretion. The aim of this study was to assess circadian changes, if any, in serum cortisol levels in female patients with FMS. Cortisol levels were estimated every 6 h during 24 h period; in 40 female patients satisfying ACR criteria for FMS (Age 36.4 ± 9.9), and 40 healthy females without FMS (Age 33.8 ± 11.1). A significant difference in the night time serum cortisol level was observed among the patients and control groups (patients, 12.9 ± 9.7 controls 5.8 ± 3.0; p < 0.01). However, no significant difference was found in serum cortisol levels in patients and control groups in the morning (patients, 28.4 ± 13.2 controls, 27.6 ± 14.5; p > 0.05), afternoon (patients, 14.4 ± 5.6 controls, 14.0 ± 6.6; p > 0.05) and evening hours (patients, 10.9 ± 5.8 controls, 8.9 ± 3.6; p > 0.05). It could be concluded that there is an abnormality in circadian secretion of cortisol in female FMS patients. 相似文献
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Obesity is one of the most important health problems, which many people suffer from it. As a chronic disease, it is a precipitating
factor for many medical conditions like hypertension, diabetes mellitus, hyperlipidemia, coronary artery disease, sleep apnea
syndrome and some malignancies (breast, uterus, prostate and colon carcinoma). With attention to this fact that obesity is
an independent risk factor associated with significant increase in morbidity and mortality, treatment of overweight individuals
is very important. One of the medications for short-term weight loss is fluoxetin. In this clinical trial study, fluoxetin
effect on weight loss induction during 8 weeks was investigated. 201 cases with BMI between 25–42 were selected randomly (113
female and 88 male) and all received fluoxetine (40 mg daily) for 8 weeks. Measurement was carried out after the 4th and 8th week of administration and 4 weeks after end of treatment. Management of 9 cases (4 due to weight gain and 5 due to headache)
were discontinued after 4 weeks of treatment. Data assessments were performed using t-test and SPSS program. Mean body weight
at first visit was 89.32±13.30kg. At the 4th, 8th week of treatment and 4 weeks after study, the mean body weight of cases reached 86.09±13.27 (p=0.00), 82.69±11.31 (p=0.00)
and 81.97±13.26 (p=0.00) respectively. Mean BMI at first visit was 34.90±5.20kg/m2. At 4th, 8th weeks of treatment it was 33.72±5.20kg/m2 and 32.40±5.18kg/m2 respectively. Mean weight loss at 4th and 8th weeks of treatment was 3.24kg and 6.67kg respectively without any weight gain at the end of the 4th week after discontinuation of the drug. Fluoxetine is an effective, well-tolerated and relatively safe drug for short-term
treatment of obesity. 相似文献
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Munjal M. Acharya Surbhi H. Khamesra Surendra S. Katyare 《Indian journal of clinical biochemistry : IJCB》2005,20(1):56-60
The effect of picrotoxin-induced convulsions on lysosomal function in rat brain were evaluated by measuring the free as well
as total acid phosphatase, cathepsin D, acid ribonuclease (RNAse II) and acid deoxyribonuclease (DNAse II) activities. Following
picrotoxin treatment the free RNAse II activity increased whereas the total activities of practically all the other enzymes
decreased. Paradoxically, the cathepsin D activity, free as well the total was completely abolished. In case of all the enzymes
the ratio of Total activity/Free activity decreased indicating increased lysosomal membrane fragility which could lead to
process of neurodegeneration in the epileptic animals. 相似文献
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BackgroundMannheimia haemolytica is the primary bacterial pathogen in causing bovine respiratory disease with tremendous annual losses in the cattle industry. The leukotoxin from M. haemolytica is the predominant virulence factor. Several leukotoxin activity assays are available but not standardized regarding sample preparation and cell line. Furthermore, these assays suffer from a high standard error, a prolonged time consumption and often complex sample pretreatments, which is important from the bioprocess engineering point of view.ResultsWithin this study, an activity assay based on the continuous cell line BL3.1 combined with a commercial available adenosine triphosphate viability assay kit was established. The leukotoxin activity was found to be strongly dependent on the sample preparation. Furthermore, the interfering effect of lipopolysaccharides in the sample could be successfully suppressed by adding polymyxin B. We reached a maximum relative P95 value of 14%, which is more than seven times lower compared to current available assays as well as a time reduction up to 88%.ConclusionUltimately, the established leukotoxin activity assay is simple, fast and has a high reproducibility. Critical parameters regarding the sample preparation were characterized and optimized making complex sample purification superfluous. 相似文献