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目的旨在明确肺结核X线分类中两型合并的分类.方法本文收集经临床、肺结核细菌学和常规胸片确诊的肺结核500例,进行X线分类的探讨.结果X线分类,原发型167例,合并胸膜炎的6例;血型播散型70例,合并胸膜炎22例;继发型306例,合并胸膜炎74例.Ⅰ～Ⅲ型肺结核合并胸膜炎102例,占总病例数的20.4%.结论依据病因、发病机理、中国结核病分类法(1998),按原发型肺结核合并结核性胸膜炎、血行散型肺结核合并结核性胸膜炎、继发型肺结核合并结核性胸膜炎,进行X线分型. 相似文献
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目的:探讨女性尿毒症患者月经期血液透析临床护理理念与方法,以提高透析疗效;方法:对我院2005年1月1日至2009年12月1日期间收治的46例年龄在16-45岁的尿毒症患者在月经期血液透析的护理情况进行分组研究;结果:观察组与对照组透析普通临床症状(头晕等)差异不大(P>0.05),但对透析有影响的症状(大出血等)则差异显著(P<0.05);结论:采取有针对性的心理疏通,提前防护及科学护理能较好地提高透析稳定性,避免透析中断,提高透析疗效. 相似文献
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目的:探讨乳腺肿瘤组织中热休克蛋白HSP70和DNA修复酶O6-甲基鸟嘌呤-DNA甲基转移酶(O6-methyguanine-DNA methytransferase,MGMT)的表达及临床意义。方法:采用免疫组织化学SABC法检测65例乳腺肿瘤组织中HSP70和MGMT的表达情况。结果:乳腺肿瘤中HSP70的阳性率为80.00%(52/65),MGMT的阳性率为60.00%(39/65),二者呈中度相关性(r=0.46)。其中,有淋巴结转移组的阳性率高于无转移组(P<0.05)。结论:HSP70和MGMT的表达率与淋巴结转移情况有关。检测HSP70与MGMT对乳腺肿瘤预后和化疗方案的选择有指导意义。 相似文献
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徐六英 《泰州职业技术学院学报》2007,7(1):68-69
目的:回顾分析颈部淋巴结结核21例病例,以探讨颈部淋巴结结核的临床特点。方法:将我院1997年8月—2005年8月期间的21例颈部淋巴结结核进行临床总结。结果:21例颈部淋巴结结核经穿刺细胞学或组织病理学确诊后予以手术切除加抗结核治疗或单纯抗结核治疗后治愈。结论:颈部淋巴结结核以颈部症状为主,明确诊断依赖于穿刺细胞学或组织病理学,以手术切除加抗结核治疗或单纯抗结核治疗后治愈。 相似文献
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C-FOS基因在胃癌及淋巴结转移癌中表达的研究 总被引：1，自引：0，他引：1
目的:研究c-fos在胃癌及淋巴结转移癌中的表达.方法:应用兔抗人c-fos多克隆抗体,SP免疫组织化方法检测76例胃癌及淋巴结转移癌组织.结果:c-fos在胃癌及淋巴结转移癌的阳性率分别为32.6%、63.3%.c-fos在淋巴结转移癌的表达率高于胃癌(P＜0.05).结论:c-fos在淋巴结癌的表达率高于胃癌,此现象说明,c-fos和癌的转移有密切的关系. 相似文献
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INTRODUCTION Colorectal cancer is the most common cancer ofthe Western world and accounts for approx.Elevenpercent of all cancer deaths in the United States.Aswith other malignancies,colorectal adenocarcinomais thought to develop through the accumulation ofgenetic alterations that inhibit cell growth.Two of theoncogenes that have been implicated in this processare bcl-2and p53,the products of which are involvedin apoptosis,cell proliferation and tumor develop-ment(Garewal et al.,1996).S… 相似文献
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目的:探讨HSP27和HSP70 mRNA在大肠癌中表达的临床意义。方法:取大肠癌标本77例,采用免疫组织化学方法检测HSP27的表达状况,从中选取36例手术标本,采用核酸原位杂交技术(ISH)检测HSP70 mRNA的表达。结果:HSP27和HSP70 mRNA在大肠癌中的阳性率分别为40.3%和66.9%,HSP27和HSP70 mRNA均与大肠癌的分化程度相关,与发生部位、浸润深度及淋巴结转移无明显相关性。结论:检测HSP27和HSP70 mRNA可作为大肠癌患者预后的一个重要指标。 相似文献
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Yun-zhen Hu Jian-wen Wang Ben-yan Luo 《Journal of Zhejiang University. Science. B》2013,14(6):496-504
Ethnicity and socioeconomic factors can influence disease susceptibility, clinical presentation, and outcome. We investigated the clinical characteristics (age, sex, seasonal variation, lesion site, symptoms, complications, prognosis, and sequelae) and risk factors for intracerebral hemorrhage (ICH) in 266 cases treated at our hospital in Hangzhou City, China, from January 2011 to December 2011. Risk of ICH increased dramatically with age; only 4.3% of cases were <30 years old, while 44.4% were >60 years of age. Men outnumbered women by 2:1 (67.3% vs. 32.7%). Single hemorrhage was most often located in the cerebral lobes (37.2% of cases), basal ganglia (34.2%), thalamus (8.3%), cerebellum (6.8%), ventricle (1.5%), and brainstem (1.1%), while 10.9% of cases exhibited hemorrhages at multiple sites. Hypertension was also a major risk factor for ICH, as 47% of all patients were hypertensive and the percentage increased with age. In hypertensive patients, the most common hemorrhage site was the basal ganglia and ICH was often associated with thrombopenia. In patients with leukemia (all forms), most hemorrhages were lobar. Warfarin- and encephalic operation-associated ICHs were all lobar. Headache was the major symptom of occipital, temporal, and frontal lobe hemorrhage. Dizziness, nausea, and vomiting were the major symptoms of cerebellum hemorrhage. Limb dysfunction was the major symptom of thalamic and basal ganglia hemorrhage. Disturbed level of consciousness was the major symptom in multisite, ventricular, parietal lobe, and brainstem hemorrhage. Hyperspasmia occurred most often in lobar hemorrhage and blurred vision in occipital lobe hemorrhage. Hospital mortality was 24.4% (n=65) with a mean delay from presentation to death of (10.5±18.5) d. The majority of fatalities were cerebral hernia cases (58.5%) and these patients also had the shortest time to death [(2.9±3.5) d]. Mortality was 100% in brainstem ICH and hemorrhagic conversion of cerebral infarct. Thrombopenia-associated ICH also had a high mortality rate (81.0%), while patients with cerebrovascular malformations and cerebral aneurysms demonstrated a much better prognosis (46.2% recovery). 相似文献
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目的：探讨热休克蛋白70（HSP70）在人乳腺癌和胃癌中的表达及其意义。方法：应用免疫组织化学的方法对64例乳腺癌和55例胃癌组织中的HSP70进行检测。结果：（1）HSP70在乳腺癌和胃癌组织中的表达分别为78．13％．61.82％。（2）乳腺癌中HSP70的表达与乳腺癌的病理类型．淋巴结转移情况及年龄未发现显著差异（P〉0．05）。（3）胃癌中HSP70的表达与肿瘤浸润深度、淋巴结转移有密切关系（P〈0．05）。结论：HSP70在乳腺癌和胃癌中均呈较高水平表达．其中在胃癌中的表达与肿瘤浸润深度、恶性程度有密切关系,HSP70在乳腺癌和胃癌的发生发展中起重要作用。HSP70可能成为乳腺癌，胃癌的诊断指标之一。 相似文献
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Zi-yi Zhu Xu Yong Rao-jun Luo Yun-zhen Wang 《Journal of Zhejiang University. Science. B》2018,19(9):718-725
Objective: McKeown esophagectomy followed by cervical and abdominal procedures has been commonly used for invasive esophageal carcinoma. This minimally-invasive operative procedure in the lateral prone position has been considered to be the most appropriate method. We describe our experiences in minimally invasive McKeown esophagectomy (MIME) for esophageal cancer. Methods: Between March 2016 and February 2018, a total of 82 patients underwent MIME by a single group in our department (a single center). All procedure, operation, oncology, and complication data were reviewed. Results: All MIME procedures were completed successfully, with no conversions to open surgery. The median operative time was 260 min, and median blood loss was 100 ml. The average number of total harvested lymph nodes was 20.1 in the chest and 13.5 in the abdomen. There were no deaths within 30 postoperative days. Twenty cases (24.4%) developed postoperative complications, including anastomotic leak in 4 (4.9%), single lateral recurrent nerve palsy in 4 (4.9%), bilateral recurrent nerve palsy in 1 (1.2%), pulmonary problems in 3 (3.7%), chyle leak in 1 (1.2%), and other complications in 7 (including pleural effusions in 4, incomplete ileus in 2, and neck incision infection in 1; 8.54%). Average postoperative hospitalization time was 12 d. Blood loss, operation time, morbidity rate, and the number of harvested lymph nodes were analyzed by evaluating learning curves in different periods. Significant differences were found in operative time (P=0.006), postoperative hospitalization days (P=0.015), total harvested lymph nodes (P=0.003), harvested thoracic lymph nodes (P=0.006), and harvested abdominal lymph nodes (P=0.022) among different periods. Conclusions: Surgical outcomes following MIME for esophageal cancer are safe and acceptable. The MIME procedure for stages I and II could be performed proficiently and reached an experience plateau after approximately 25 cases. 相似文献
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通过对25例维持性血液透析患者的静脉留置导管的护理进行总结,探讨维持性血液透析患者静脉留置导管的护理方法。护理重点包括严格无菌操作和及时准确地处理并发症,并做到使用、护理得当,则可以维持静脉留置导管通畅性,延长使用时间,保证透析顺利有效地进行。 相似文献
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目的探讨普通型2019冠状病毒病(COVID-19)患者的临床表现与高分辨率CT(HRCT)的影像特征。方法回顾性分析我院收治的25例COVID-19确诊患者的临床资料及胸部CT检查,进一步分析其临床特征、实验室指标及HRCT影像学特征。结果我院收治的25例COVID-19患者均为普通型,发热(19/25,76%),干咳(18/25,72%);所有患者白细胞计数均正常,淋巴细胞计数不同程度减少(15/25,60%),血沉增快(12/25,48%),C反应蛋白升高(10/25,40%),出现降钙素原降低(2/25,8%);平均住院日为19.8±3.9天,从出现临床症状到CT检查阳性平均时间为4.9±2.7天。首次胸部HRCT病灶分布为单侧9例(36%,左肺4/25,16%;右肺5/25,20%),双侧16例(64%);20例(80%)病灶分布位于周边,5例(20%)位于周边为主及中心同时受累。HRCT表现中单纯磨玻璃影(GGO)为25例(100%),GGO伴局灶性实变为5例(20%),4例(16%)伴片状实变影。在第二次HRCT检查中,大部分患者病灶增多、范围变广,局部病灶融合,并见支气管充气征。结论普通型COVID-19患者临床表现相对较轻,HRCT是其诊断和评估的重要手段。 相似文献
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炎性乳腺癌的诊断和治疗 总被引：1，自引：0，他引：1
[目的]:探索炎性乳腺癌的诊断和治疗.[方法]:10例经病理或细胞学检查确诊的炎性乳腺癌先给2~3个周期的CAF(阿霉素+环磷先胺+氟尿嘧啶)方案化疗,然后行总量的2/3量的乳腺及同侧腋窝的放射治疗,放疗结束后休息2周即行乳癌根治切除术,术后切口愈合后再给剩余1/3量的放射治疗,照射胸壁及同侧腋窝和锁骨上使放射总量达到60~70 Gy/野,在放疗前后穿插化疗(CAF)4个周期.[结果]:1例患者未完成治疗出院后1个月死亡.9例患者完成上述序惯治疗,全部病例乳腺红肿、高张消退,乳腺内肿块及同侧腋窝淋巴结明显缩小.手术切除标本检查有5例乳腺内找到癌灶,其中典型炎性癌1例、单纯癌2例、硬癌2例,4例乳腺组织内未找到癌灶.同侧腋窝淋巴结见癌转移7例,同侧锁骨上淋巴结见癌转移2例.生存时间1~28个月,中位生存时间12个月.[结论]:炎性乳腺癌通过序惯治疗可以提高治疗的有效性、延长生命,提高生存质量. 相似文献
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目的：通过对乳腺癌原代细胞培养。检测化疗药物对癌细胞的抑制率。探讨乳腺癌不同组织学类型、年龄及淋巴结转移情况对化疗药物的敏感性。方法：收集109例手术切除新鲜乳腺癌标本．进行原代细胞培养。采用四甲基偶氮唑盐（MTT）法检测癌细胞对三组抗癌药物的敏感性。结果：乳腺癌的敏感率由高到低依次为CAF（33．0％）、TA（31．2％）和CMF（26．6％）。无论年龄、组织学类型及是否有淋巴结转移各组间比较其敏感性均无显著差异（P〉0．05）。结论：1．MTT法对乳腺癌治疗时选择化疗药物具有重要价值；2．乳腺癌细胞对CAF、TA、CMF敏感。 相似文献
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目的:分析预见性护理是否减少了血液透析患者低血压和不良情绪的影响。方法:以我院2019年1月-2020年1月100例尿毒症血液透析患者为研究对象,采用随机法分为两组。对照组给予常规护理,实验组实施预见性护理。每组患者在实验前、后采用评分的方式调查得出其焦虑评分、护理满意度评分;实验结束后,由责任护士对患者的治疗依从性进行评分,并观察两组别并发症(低血压)的出现例数。最后,将得到的数据采用SPSS17.0软件进行对比分析。结果:实验组有效降低了透析患者的不良情绪、焦虑程度以及低血压的发生率(P<0.05);同时,实验组也有效提高了透析患者的护理工作满意度及治疗依从性(P<0.05),维护了患者良好的心态和医患关系。结论:预见性护理能够有效减少血液透析患者在治疗所受不良情绪和低血压的影响,提升了血液透析患者的治疗依从性和治疗效果。 相似文献
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陶爱华 《泰州职业技术学院学报》2013,(6):68-70
目的 探讨系统性干预对维持性血液透析便秘患者的效果.方法 对48例维持性血液透析患者进行心理、饮食、运动、按摩、药物等一系列系统性干预,干预期6周.采用便秘症状及疗效评估问卷了解干预效果.结果 对维持性血液透析便秘患者进行系统性干预后,排便困难,粪便性状,排便时间,下坠、不尽、胀感,排便频率,腹胀评分均较干预前显著改善,差异有统计学意义（P＜0.05）.系统性干预后的总有效率为70.83％.结论 对维持性血液透析患者积极进行系统性干预,可明显改善便秘症状,提高临床疗效,减轻患者的痛苦,值得推广使用. 相似文献
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目的:总结70岁以上老年普胸病人的手术指征,手术治疗及围手术期处理体会.方法:1996.6～2005.6月我院共施行普胸手术578例,其中70岁以上的老年患者118例,占20.4%(118/578).现对118例70岁以上老年患者手术治疗及围术期处理进行回顾性分析.结果:术中术后出现或加重的循环系统并发症34例占28.8%(34/118);呼吸系统并发症29例占24.6%(29/118);消化系统并发症19例占16.1%(19/118);精神神经系统并发症10例占8.5%(10/118);经综合治疗均治愈出院.术后1、3、5年生存率分别为90.0%、77.6%、42.8%.结论:对70岁以上老年普胸病人围术期处理十分关键,因老年人全身各系统器官的衰退及疾病本身的并发症相互叠加,风险较大;但只要手术指征选择合适,手术中间处理严密,围术期处理恰当,70岁以上老年患者施行普胸手术效果理想. 相似文献
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川崎病合并支原体感染14例诊治体会 总被引：1，自引：0，他引：1
目的探讨小儿川崎病合并支原体感染的临床特征及诊治体会。方法对临床诊断为川崎病合并支原体感染的患儿进行回顾性分析。结果 14例患儿均有发热;球结合膜充血13例,皮疹8例,口腔粘膜改变14例,手足硬性水肿、指（趾）脱皮14例,颈部淋巴结肿大12例,卡痕、肛周粘膜潮红5例。白细胞增高、血C R P增高9例,心脏彩超示冠状动脉病变（C AL）2例。所有患儿均用阿奇霉素序贯治疗,并早期大剂量人血丙种球蛋白（IVIG）及阿司匹林、潘生丁治疗,13例治愈,1例呈IVIG不反应,再次予以IVIG后痊愈。结论肺炎支原体可能参与川崎病的发病。 相似文献
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Basic factual information about disease is the cornerstone of health promotion and disease prevention interventions. Previous studies have shown that content analysis of the questions asked of service providers can elucidate the information needs of service consumers. Questions asked by individuals at known high risk for HIV infection have not previously been examined. The current study analyzed 944 questions asked by 634 patients receiving HIV‐risk‐reduction counseling services at an urban sexually transmitted infections clinic. Questions were captured from audiotape recordings of risk‐reduction counseling sessions that were subsequently transcribed and content‐analyzed. A total of 49% of clients asked at least one question in their counseling session. Asking counselors questions was not associated with demographic characteristics or AIDS‐related knowledge. Questions were found to fit the AIDS information content structure identified in past research. The most common questions asked by sexually transmitted infection clients concerned condoms and other barrier methods of prevention (15%), HIV symptoms and disease progression (14%) and HIV antibody testing (11%). These results show that many individuals at high risk for HIV infection have substantial information needs, and that basic education about AIDS facts should not be neglected in HIV prevention interventions. 相似文献