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1.
Purpose: This study aimed to investigate the relationship between fundamental movement skills (FMS) and markers of health among a cohort of Irish primary school children. Methods: Participants (N = 296, mean age: 7.99 ± 2.02 years) were senior infant (n = 149, mean age: 6.02 ± 0.39 years) and 4th class (n = 147, mean age: 9.97 ± 0.40 years) students from three primary schools in Cork, Ireland. FMS proficiency (TGMD-2) and markers of health (BMI percentile, waist circumference percentile, blood pressure percentiles, resting heart rate, cardiorespiratory fitness, objectively measured physical activity; PA) measurements were recorded. Correlation and hierarchical stepwise multiple linear regression analyses were conducted to investigate the relationship between FMS and markers of health. Results: A small, positive relationship was found between FMS (Gross Motor Quotient; GMQ) and cardiorespiratory fitness with small negative correlations between GMQ and 550 m time SDS among 6-year-olds (r(129) = ?.286, p < .05) and 10-year-olds (r(132) = ?.340, p < .05). A moderate, positive correlation was found between GMQ and light PA (r(71) = .400, p < .05). Small positive correlations were revealed between GMQ and moderate PA (r(71) = .259, p < .05) and between GMQ and total PA (r(71) = .355, p < .05). After adjusting for age, sex, the interaction effect of age and sex, and school attended, FMS explained 15.9% and 24.8% of the variance in 550 m time SDS among 6- and 10-year-olds, respectively, and 6% and 6.5% of the variance in light PA and moderate PA, respectively. After adjusting for age and sex, FMS explained 11.6% of the variance in total PA. Conclusion: A wide range of FMS is important for children’s cardiorespiratory fitness and PA.  相似文献   

2.
ABSTRACT

Purpose: The purpose of this study was to examine the predictive relationship among physical activity, health-related fitness, and on-task classroom behavior in children using a discriminant function analysis. Method: Participants were a convenience sample of children (N = 533; Mage = 8.8 ± 1.9 years) recruited from 77 1st- through 5th-grade classrooms at 3 low-income schools in a capital city in the Southwest United States. Percent of the school day spent in sedentary behavior (%SED), moderate-to-vigorous physical activity (%MVPA), and health-related fitness scores (body mass index [BMI] and Progressive Aerobic Cardiovascular Endurance Run [PACER] laps) were assessed during school hours. Classrooms were observed for on-task behavior during the academic year with the use of 5-s momentary time sampling methodology. A discriminant function analysis was performed using a binary on-task behavior outcome, stratified by an 80% on-task behavior cut point. Results: The results yielded 1 function (r2 = .26, F = 13.1) explaining approximately one quarter of the total variance. The standardized function coefficients were ?.29, .29, ?.48, and .48 for %SED, %MVPA, BMI, and PACER laps, respectively. The sensitivity and specificity of the derived function for classifying a child into an on-task or off-task classroom were .79 and .73, respectively. Children who belonged to classrooms that achieved 80% on-task behavior displayed shorter times in sedentary behaviors (d = 1.01), lower BMI (d = 0.13), and higher PACER scores (d = 0.22) compared with children who belonged to off-task classrooms. Conclusion: School-day physical activity behaviors and health-related fitness scores can moderately discriminate children who belong to classrooms from low-income schools that are categorized as being sufficiently on task.  相似文献   

3.
Abstract

The purpose of this cross-sectional study was to examine the relationship between objectively measured physical activity, sedentary time, and cardiorespiratory fitness in a diverse sample of youth. Participants were recruited from three middle schools and completed assessments of height, weight, cardiorespiratory fitness, and wore an accelerometer for a minimum of four days. Hierarchical general linear models controlling for age, body mass index (BMI) percentile, and sex were used to evaluate the association of time (minutes per day) spent sedentary, and in moderate physical activity and vigorous physical activity with cardiorespiratory fitness (i.e., heart rate response [beats per minute], dependent variable). Results indicated age (β = –0.16, P < 0.05), BMI percentile (β = 0.33, P <0.05), being male (β = 0.17, P < 0.05), sedentary time (β = 0.11, P <0.05), moderate (β = –0.03, P > 0.05) and vigorous (β = –0.22, P < 0.05) physical activity explained 29% of the variance in cardiorespiratory fitness. Evaluation of fitness among high sedentary/high vigorous, high sedentary/low vigorous, low sedentary/low vigorous, and low sedentary/high vigorous groups (defined by the median split) showed that high levels of vigorous activity removed the detrimental effect of high levels of sedentary time on cardiorespiratory fitness. These analyses suggest that the negative impact of sedentary time can be mitigated by engaging in vigorous activity.  相似文献   

4.
Abstract

With cardiovascular fitness (CVF) as the dependent variable, relationships with habitual level of physical activity, age, gender, and body mass index (BMI) were investigated in a sample of 93 high adiposity and 93 low adiposity children, ages 8 to 13. A physical activity score (PAS) was computed for each child from a 2-day observation period. A physical working capacity index from cycle ergometry (PWC170) was the measure of CVF. Low and high adiposity samples were classified by a median split (42.9 mm) on the sum of three skinfold measures (tricep, suprailiac, subscapula). For the high adiposity sample, PAS, age, BMI, and gender were significant and the overall model was significant (p < .001), accounting for 38 % of variance in PWC170. In the low adiposity sample, gender (p < .04) was significantly related to CVF, but the overall model was not significant (p < .35). PAS, thus, was a significant predictor of CVF among the high adiposity children, but not the low adiposity children. Mechanisms that may account for this difference include greater work for equal activity among the obese, a ceiling effect on CVF among the low adiposity children, or differences in hormonal or metabolic factors mediating the activity-CVF relationship.  相似文献   

5.
Physical activity is important in obesity prevention, but the effectiveness of different physical activity modalities remains to be determined among children. The main purpose of this study was to compare the effects of a 6-month soccer programme and a traditional physical activity programme on changes in body composition, cardiometabolic risk factors, inflammatory and oxidative markers, cardiorespiratory fitness and perceived psychological status in obese boys. Eighty-eight boys (8–12 years; BMI > +2 standard deviations of WHO reference values) participated in one of three groups: soccer, traditional activity and control. Soccer and traditional activity programmes involved 3 sessions per week for 60–90 min at an average intensity of 70–80% of maximal heart rate. Control group participated in activities of normal daily living. All boys participated in school physical education, two sessions per week of 45–90-min. Measurements were taken at baseline and after 6 months, and included body size and composition, cardiometabolic risk factors, inflammatory and oxidative markers, cardiorespiratory fitness and perceived psychological status. Physical activity and dietary intake were assessed before and immediately following the intervention. The three groups had similar characteristics at baseline. After 6 months, both intervention groups had significantly lower relative fatness (% fat), waist circumference and total cholesterol, and higher cardiorespiratory fitness, self-esteem, perceived physical competence and attraction to physical activity compared with control group. In conclusion, physical activity interventions over 6 months positively influenced several indicators of health status among obese boys. The results also suggested that soccer has the potential as an effective tool for the prevention and reduction of childhood obesity and associated consequences.  相似文献   

6.
Participation in youth sport is assumed to promote and contribute towards more physically active lifestyles among children and adolescents. The aim of this study was to examine inter-participant variability in objectively measured habitual physical activity (PA) behaviours and sedentary time among youth sport participants and their implications for health. One-hundred-and-eighteen male youth sport footballers (Mean ± s = 11.72 ± 1.60) wore a GT3X accelerometer for 7 days. Average daily PA [min · day?1, in light (LPA), moderate (MPA), vigorous (VPA) and combined moderate-to-vigorous (MVPA)] and sedentary time were calculated. Participants’ body mass index adjusted for age and sex (BMI–standard deviation score), per cent body fat (BF%), waist circumference and cardiorespiratory fitness were assessed. Results revealed that variability in daily PA behaviours and sedentary time (min · day?1) was associated with BMI–standard deviation score [VPA (?), MVPA (?)], BF% [sedentary time (+), VPA (?), MVPA (?)], waist circumference [sedentary time (+), LPA (?)] and cardiorespiratory fitness [sedentary time (?), MPA (+), VPA (+), MVPA (+)]. Whilst sedentary time and MVPA were not related to health outcomes independent of one another, associations with markers of adiposity and cardiorespiratory fitness were stronger for sedentary time. Sedentary time was also significantly positively related to waist circumference independent of VPA. Results demonstrate inter-participant variability in habitual PA and sedentary time among youth sport participants which holds implications for their health. Thus, promoting PA and, in particular, reducing sedentary time may contribute towards the prevention of adverse health consequences associated with a physically inactive lifestyle for children and adolescents active in the youth sport context.  相似文献   

7.
The aims of this study were to quantify the effects of factors such as mode of exercise, body composition and training on the relationship between heart rate and physical activity energy expenditure (measured in kJ?·?min?1) and to develop prediction equations for energy expenditure from heart rate. Regularly exercising individuals (n = 115; age 18?–?45 years, body mass 47?–?120?kg) underwent a test for maximal oxygen uptake ([Vdot]O2max test), using incremental protocols on either a cycle ergometer or treadmill; [Vdot]O2max ranged from 27 to 81?ml?·?kg?1?·?min?1. The participants then completed three steady-state exercise stages on either the treadmill (10?min) or the cycle ergometer (15?min) at 35%, 62% and 80% of [Vdot]O2max, corresponding to 57%, 77% and 90% of maximal heart rate. Heart rate and respiratory exchange ratio data were collected during each stage. A mixed-model analysis identified gender, heart rate, weight, [Vdot]2max and age as factors that best predicted the relationship between heart rate and energy expenditure. The model (with the highest likelihood ratio) was used to estimate energy expenditure. The correlation coefficient (r) between the measured and estimated energy expenditure was 0.913. The model therefore accounted for 83.3% (R 2) of the variance in energy expenditure in this sample. Because a measure of fitness, such as [Vdot]O2max, is not always available, a model without [Vdot]O2max included was also fitted. The correlation coefficient between the measured energy expenditure and estimates from the mixed model without [Vdot]O2max was 0.857. It follows that the model without a fitness measure accounted for 73.4% of the variance in energy expenditure in this sample. Based on these results, we conclude that it is possible to estimate physical activity energy expenditure from heart rate in a group of individuals with a great deal of accuracy, after adjusting for age, gender, body mass and fitness.  相似文献   

8.
有氧健身操训练对中年肥胖女性体成分影响的研究   总被引：1，自引：0，他引：1  
本研究旨在利用我部现有的科研力量和人员技术优势,通过对40多名在健身俱乐部进行有氧健身操锻炼的年龄在30-45岁女性肥胖(超过标准体重20-30)者进行为期3个月的有氧健身操锻炼,然后对锻炼前后的腰臀比(WHR)和体重指数(BMI)进行测量,即有氧健身操训练对中年肥胖女性体成分影响的研究,评价其减肥效果,结合膳食指导和健康咨询,逐步修正健身操练习者的运动量,使健身练习者达到降重不降水,降脂增肌的最佳减肥效果,确保减肥过程的安全、有效。  相似文献   

9.
Abstract

The relationship between cardiorespiratory (CR) endurance performance and various physiological and anthropometric measures was determined in 33 college women. Bivariate and multiple regression analysis was used to determine the extent to which the independent variables, individually and collectively, accounted for the variance in the 2-km run. Independent variables included maximal [Vdot]O2, [Vdot]E, R, and HR; submaximal HR; response to a standard workload of steps during a l-min steptest; percent body fat predicted from skinfolds; body circumferences; height; and weight. [Vdot]O2 max in ml/kg of body weight accounted for the greatest amount of variance in run time (39%). The steptest added 5.9%, the other physiological measures collectively added 9.7%, while the anthropometric measures collectively added only 2.1% to the explained variance for a total of 56.7%. Although anthropometric factors play a role in CR endurance performance, their influence is small in this population when physiological factors are accounted for.  相似文献   

10.
BackgroundPuberty is a critical time in the development of overweight and obesity. The aim of this study was to examine relationships between measures of adiposity, cardiovascular fitness, and biomarkers of cardiovascular disease risk in adolescents.MethodsIn a cross-sectional study design, 129 girls and 95 boys aged 12.9–14.4 years at various stages of puberty were included, along with their mothers (n = 217) and fathers (n = 207). Anthropometric assessments of adiposity were made, along with cardiovascular physical fitness, using the 20-m shuttle run test, and biomarkers associated with cardiovascular risk, including glucose, insulin, triglyceride, fibrinogen, and C-reactive protein (CRP) concentrations.ResultsWaist-to-height ratio values were similar in boys and girls and correlated positively with diastolic blood pressure, insulin, triglyceride, fibrinogen, and CRP concentrations, and inversely with cardiovascular fitness scores. Skinfold thickness measurements were higher in girls. High-molecular-weight adiponectin concentrations were lower in boys than girls, particularly in late puberty, and CRP levels were higher. Cardiovascular fitness, maternal body mass index (BMI), and paternal BMI contributed independently to the variance in waist measurements in girls and boys. Gender, triceps skinfold thickness, and weight-to-height ratio, but not parental BMI, contributed independently to the variance in cardiovascular fitness.ConclusionThere is a relationship between measures of adolescent adiposity and parental weight that involves factors other than cardiovascular fitness. Adolescent boys have relatively more abdominal fat than girls and a tendency to have a proinflammatory profile of biomarkers. These observations suggest that family and social environmental interventions are best undertaken earlier in childhood, particularly among boys.  相似文献   

11.
The prevalence of obesity in children has increased dramatically during the past decades in Europe and understanding physical fitness and its components in children is critical to design and implement effective interventions. The objective of the present study was to analyse the association between physical fitness (aerobic, speed, agility, power, flexibility and balance) and body mass index (BMI) in pre-pubertal children. A total of 2411 healthy schoolchildren (7–11 years) participated in this study. Anthropometric characteristics and body composition were assessed by skinfold thickness. Physical fitness was measured by nine physical fitness tests: endurance running, 20 m running speed, agility, handgrip strength, standing long jump and squat jump, sit and reach, medicine ball forward throw and static balance. No relevant differences were observed between boys and girls regarding anthropometric characteristics, body composition and physical fitness. However, overweight and obese children showed significantly lower physical fitness levels in endurance running, speed and agility (mean: +18.8, +5.5 and +14.5% of time to complete tasks, respectively), lower limb power normalised to body mass (?23.3%) and balance tests (number of falls: +165.5%) than their normal weight counterparts. On the other hand, obesity did not affect handgrip, throwing and flexibility. In conclusion, increased BMI was associated with lower performance capabilities limiting proper motor skill development, which directly affects the ability of children to take on sports skills. Actions undertaken to promote children's wellness and fitness should be prioritised and introduced early in life with the aim of enhancing physical fitness as well as preventing overweight and obesity.  相似文献   

12.
The aim of this study was to investigate the cross-sectional and prospective associations between physical activity and body composition in adolescence. This is a prospective study, including 4,103 adolescents belonging to the Pelotas (Brazil) 1993 birth cohort, who were followed up at the mean ages of 11.3 and 14.7 years. Subsample analyses included 511 individuals with accelerometry and deuterium dilution data at 13.3 years. Sum of skinfolds at age 11.3 years was highly correlated with skinfolds at age 14.7 years (rho = 0.74, P < 0.001). More than 85% of participants remained in the same quintile or changed by not more than one quintile during the 3.4 year period. Tracking of physical activity was considerably lower, although still significant; the correlation was 0.24 (P < 0.001) and 61.4% of the adolescents moved one or less quintiles. In fully-adjusted models, no significant cross-sectional or longitudinal associations were found between physical activity and body composition, neither in boys nor in girls. These null results were confirmed in the 511 individuals with accelerometry and deuterium data. We provide evidence of tracking of physical activity and particularly body composition during adolescence. Our results do not support the hypothesis that physical activity and fatness are strongly related in adolescents.  相似文献   

13.
This study assessed the association of fitness and fatness with cognitive function in women with fibromyalgia, and the independent influence of their single components on cognitive tasks. A total of 468 women with fibromyalgia were included. Speed of information processing and working memory (Paced Auditory Serial Addition Task), as well as immediate and delayed recall, verbal learning and delayed recognition (Rey Auditory Verbal Learning Test) were assessed. Aerobic fitness, muscle strength, flexibility and motor agility were assessed with the Senior Fitness Test battery. Body mass index, percent body fat, fat-mass index and waist circumference were measured. Aerobic fitness was associated with attention and working memory (all, p < 0.05). All fitness components were generally associated with delayed recall, verbal learning and delayed recognition (all, p < 0.05). Aerobic fitness showed the most powerful association with attention, working memory, delayed recall and verbal learning, while motor agility was the most powerful indicator of delayed recognition. None of the fatness parameters were associated with any of the outcomes (all, p > 0.05). Our results suggest that fitness, but not fatness, is associated with cognitive function in women with fibromyalgia. Aerobic fitness appears to be the most powerful fitness component regarding the cognitive tasks evaluated.  相似文献   

14.
Purpose: Physical education (PE) in school provides opportunities for physical activity (PA) engagement and reportedly results in improved health-related fitness. This study explored the underlying correlations between PE and activity-related healthy lifestyle practices with current level of cardiorespiratory fitness. Methods: A total of 13,138 students age 14 (boys = 7,094, 54.0%) in Grade 8 from the China National Assessment of Educational Quality - Physical Education & Health 2015 were included in this study. Two independent structural equation modeling (SEM) analyses were conducted to obtained sex-specific results. Data included the results of the 15-m progressive aerobic cardiovascular endurance run (PACER) and questionnaire data regarding PE curriculum implementation, learning and practice, perceived support from PE teachers, PE facilities, PE equipment, activity-related healthy lifestyle practices, habitual physical fitness, appropriate method of physical fitness, and breakfast eating habits. Structural equation modeling was applied to examine the associations between variables, controlling for socioeconomic status, the location of schools, and Body Mass Index. Results: There was a statistically significant relationship between cardiorespiratory fitness and activity-related healthy lifestyle practices, which was somewhat positively impacted by skill learning and practice and perceived support from PE teachers. Together, the boy’s model explained 21.8% of the variance in cardiorespiratory fitness, whereas the girl’s model explained 15.9%. Conclusions: A well-organized PE program is related to students’ activity-related healthy lifestyle practices, and consequently provides an improvement to cardiorespiratory fitness.  相似文献   

15.
The aims of this study were to describe normative values and seasonal variation of body composition in female cyclists comparing female road and track endurance cyclists, and to validate the use of anthropometry to monitor lean mass changes. Anthropometric profiles (seven site skinfolds) were measured over 16 years from 126 female cyclists. Lean mass index (LMI) was calculated as body weight?×?skinfolds?x. The exponent (x) was calculated as the slope of the natural logarithm of body weight and skinfolds. Percentage changes in LMI were compared to lean mass changes measured using dual-energy X-ray absorptiometry (DXA) in a subset of 25 road cyclists. Compared to sub-elite and elite cyclists, world class cyclists were (mean [95% CI]) 1.18?kg [0.46, 1.90] and 0.60?kg [0.05, 1.15] lighter and had skinfolds that were 7.4?mm [3.8, 11.0] and 4.6?mm [1.8, 7.4] lower, respectively. Body weight (0.41?kg [0.04, 0.77]) and skinfolds (4.0?mm [2.1, 6.0]) were higher in the off-season compared to the early-season. World class female road cyclists had lower body weight (6.04?kg [2.73, 9.35]) and skinfolds (11.5?mm [1.1, 21.9]) than track endurance cyclists. LMI (mean exponent 0.15 [0.13, 0.18]) explained 87% of the variance in DXA lean mass. In conclusion, higher performing female cyclists were lighter and leaner than their less successful peers, road cyclists were lighter and leaner than track endurance cyclists, and weight and skinfolds were lowest early in the season. LMI appears to be a reasonably valid tool for monitoring lean mass changes.  相似文献   

16.
Abstract

The purpose of this study was to determine the effects of aerobic dance on physical work capacity, cardiovascular function and body composition of young middle-aged women. Maximal oxygen uptake ([Vdot]O 2 max), heart rate during submaximal treadmill walking, resting heart rate and blood pressure, and body composition were determined before and after a 10-week aerobic dance conditioning program in 28 women (18 experimental and 10 control), aged 25 to 44 years. During the 10-week treatment period, the experimental subjects participated in 45 min of aerobic dance at 70–85% of the heart rate reserve, 3 days · week –1,whereas the control group did not participate in any regular strenuous physical activity. Changes in the experimental group were significantly greater than in the control group for [Vdot]O 2 max expressed in 1 · min –1 or relative to body weight or fat-free weight (5 to 7% vs. – 5 to – 8%), time on a continuous grade-incremented walking treadmill test (16% vs. 1%), heart rate during submaximal stages of the treadmill test (– 9% vs. 1%) and resting heart rate (– 8% vs. 2%). Resting systolic and diastolic blood pressure; body weight; percent fat, fat weight, and fat-free weight estimated using underwater weighing; sum of seven skinfolds; and sum of seven circumferences did not change significantly in either group. It was concluded that aerobic dance performed 30–45 min, 3 days · week –1 for 10 weeks significantly improves physical work capacity and cardiovascular function, but without dietary control, does not alter body composition in sedentary middle-aged women.  相似文献   

17.
目的：描述上海市20～59岁成年人体脂率（BF%）、身体质量指数（BMI）、腰围（WC）等形态指标人群分布特征,探讨BF%、BMI、WC的异同点。方法：基于2020年第五次国民体质监测上海市20～59岁成年人数据库,纳入26 826名研究对象,分析不同性别、年龄组成年人BF%、BMI、WC特征以及相关人群分布。结论：上海市成年男性WC随年龄增长而增大,成年女性BF%和WC随年龄的增长而增长。以BF%、BMI、WC 3个指标评判上海市20～59岁成年人超重与肥胖情况时存在着一定的差异。上海市成年男性以WC为标准检出肥胖率最高,以BF%为标准检出超正常标准率最高;上海市成年女性以BF%为标准检出超正常标准率及肥胖率最高。BMI与BF%相结合,或与WC相结合,可以反映身体脂肪含量及比例,以及脂肪分布。  相似文献   

18.
Objectives: This study’s aims were to describe the development of physical activity, physical fitness (PF), subjective (physical complaints (PC)) and objective (Body mass index (BMI)) health measures and to examine the relationship between the development trajectories. In addition, the study also aimed to assess the influence of sociodemographic determinants (age, sex, socioeconomic status (SES)) in German adults over a period of 18 years. Methods: The longitudinal study population comprises of 721 men and women, aged 33–76 years over the study period. There was self-report of physical activity and PC and testing of physical fitness and BMI in each study year (1992, 1997, 2002 and 2010). Latent growth curve models were used to analyse the development. Results: Physical activity slightly increased while fitness, PC and BMI worsened over the course of 18 years. Sex, age and SES play important roles concerning physical activity, fitness and health. Several integrative associations could be detected between physical activity, fitness, PC and BMI as well as their trajectories. In particular, high initial levels of physical activity and fitness protect from high PC and BMI.The slope of physical activity was not significantly associated with slopes of fitness, PC and BMI. However, increase of fitness resulted in decrease of PC. Conclusions: A general positive development regarding the amount of physical activity could be detected. However, if it is only an unsystematic increase of physical activity, this is not in itself enough to achieve health benefits. The strengthening of fitness should be focused when increasing physical activity, since only then a health benefit is possible.  相似文献   

19.
Abstract

This study examined whether body perception (BP) and body satisfaction (BS) among adolescents correspond with healthy body size criteria as recommended by various world health authorities, and assessed the relationships between BP and BS and physical activity (PA) among adolescents. Participants included 6274 Israeli boys and girls from grades 7–12 who took part in the first Israeli Health and Nutrition Youth survey. Data regarding their BP and BS, body mass index (BMI) and PA were gathered. Among the overweight and obese participants, 66.4% and 40.6% of the boys, respectively, and 46.7% and 26.1% of the girls, respectively, perceived their body shape and size as satisfactory (OK). Another important finding was that overweight and obese girls were three times more active than underweight girls, and the highest per cent of active boys appeared among the overweight boys or those who perceived themselves as fat. Regression analyses revealed that BMI, gender and age accounted for 29.8% of the variance in participants' BP; BMI, gender and age accounted for 22.1% of BS variance, and PA was not related to either BP or BS. In conclusion, adolescents do not perceive their body according to healthy body size criteria recommended by various world health authorities. In addition, PA as a variable does not explain body image. Therefore, increasing body awareness seems to be a fundamental step in programs that aim to reduce obesity.  相似文献   

20.
The effects of training on FNDC5/irisin and its association with fitness and metabolic marker improvements induced by training have been poorly investigated in humans. Thus, the present study assessed the effects of combined training (CT) on FNDC5/irisin levels, metabolic markers and fitness adaptations in obese men. Middle-age obese men (age 49.13?±?5.75, body mass index (BMI) 30.86?±?1.63) were randomly distributed in the CT group (n?=?12) and control group (CG n?=?10). The CT consisted of strength followed by aerobic training, 3 times/week, for 24 weeks. Body composition, physical fitness, plasma FNDC5/irisin, biochemical markers and metabolic scores/index were evaluated. CT maintained FNDC5/irisin levels (µg/mL) (pre: 4.15?±?0.32, post: 4.21?±?0.32; p?=?.96) and improved body composition, metabolic and physical fitness markers. In the CG, decreased FNDC5/irisin (µg/mL) (pre: 4.36?±?0.23, post: 3.57?±?0.94; p?=?.01) and reduced strength (supine exercise/kg) (pre: 71?±?14.7, post: 60.1?±?14.05; p?<?.01) were observed, along with a trend to increase HOMA-IR (pre: 2.63?±?1.11, post: 3.14?±?1.27; p?=?.07) and other indicators of metabolic deterioration. An inverse correlation was found between the change (Δ%) in levels of FNDC5/irisin and Δ% glucose, Δ% total cholesterol, Δ% triglycerides and Δ% waist circumference, in addition to a positive relation with Δ% muscle strength. In conclusion, CT maintained FNDC5/irisin levels and provided metabolic and fitness benefits. The correlation between FNDC5/irisin changes and metabolic parameters, as well as the FNDC5/irisin reduction associated with fitness and metabolic worsening in the CG, suggests a relationship between FNDC5/irisin and a healthy metabolic status in humans.  相似文献   

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