共查询到20条相似文献，搜索用时 35 毫秒
1.
Asma Ahmed Banishree Saha Anand Patwardhan Shwetha Shivprasad Dipankar Nandi 《Resonance》2009,14(5):455-471
How do we remain healthy, for the most parts, in the midst of an environment teeming with opportunistic and infectious microbes, potential carcinogens and allergens? The fact is that our immune system, by and large, does a fine job in protecting us. It is therefore important to understand the organization of the immune network, which is broadly categorized into two groups: innate and adaptive. Cells involved in innate immunity are the first to come into contact with invading microbes, similar to the border security force, and respond rapidly but in a non-specific manner. On the other hand, the cells involved in adaptive immunity are slower to respond but act in a very specific manner. Though the primary response is slow, the secondary response is much faster and demonstrates memory. This article will focus on some important features and key players involved in the adaptive immune response. The first part deals with the humoral immune response mediated mainly by immunoglobulins produced by the B cells. The second part deals with T cells, the Major Histocompatibility Complex (MHC)-encoded molecules, and Recombination Activating Genes (RAG) responsible for generating diverse B-cell receptors (BCR) and T-cell receptors (TCR). With the advent of newer and smarter infectious agents, it is important to understand the working of the immune network as more research in this area may facilitate the development of better protective strategies. 相似文献
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Mukta Deobagkar-Lele Chetana Bhaskarla Rajkumar Dhanaraju Manikandan Ponnusamy Dipankar Nandi 《Resonance》2012,17(10):974-995
The 2011 Nobel Prize inMedicine or Physiology was awarded to Jules Hoffmann, Bruce Beutler and Ralph Steinman for their contributions in the area of Innate Immunity. This review introduces the readers to innate immunity and links the studies of the awardees to this area of research. The cells and mechanisms involved in the innate immune response are reviewed with a special emphasis on the discovery of the Toll receptors in Drosophila and the Toll-like receptors in mammals. The importance of the innate response during inflammatory conditions is discussed and examples of genes related to innate immunity that cause disease are also highlighted. Finally, the roles of innate immunity in modulating adaptive immune response, especially with respect to dendritic cells, are discussed. Further studies in this area are likely to enhance our understanding of the immune response and may lead to drugs to ameliorate excessive inflammatory responses. 相似文献
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Carolyn Anderson 《British Journal of Special Education》2011,38(1):9-18
This article presents research undertaken as part of a PhD by Carolyn Anderson who is a senior lecturer on the BSc (Hons) in Speech and Language Pathology at the University of Strathclyde. The study explores the professional learning experiences of 49 teachers working in eight schools and units for children with additional support needs in Scotland. In particular, she examines the professional learning experiences of teachers working with children with speech, language and communication needs (SLCN) combined with moderate‐to‐severe learning difficulties. While the teachers under study predominantly engaged with informal professional learning, she observes that they often expressed a lack of confidence in this form of professional development, tending to value formal learning regardless of impact. In response she raises a number of important questions about the role of Initial Teacher and Postgraduate Education and the ways in which schools understand reflective practice. 相似文献
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The main argument of this article is that metacognition is an important part of human abilities, which are, in turn, forms of developing expertise. To the extent that our goal is to understand the bases of individual differences in student academic success, we need to understand metacognition as representing part of the abilities that lead to student expertise, but only as part. 相似文献
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网络政治是民主现代化的重要内容,是公民参与政治、了解政治的重要载体和途径,网民在网络政治中的影响越来越大,对政府决策、政务管理都产生了极大影响。网民在网络政治中扮演着积极和消极的双重角色,对完善中国特色社会主义民主制度起着促进作用。 相似文献
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高岚岚 《福建教育学院学报》2009,10(1):119-121
防火墙作为网络安全使用量最大的安全产品,是实施网络安全策略的重要组成部分,一直受到网络信息用户和研发机构极大关注。本课题针对目前国内外通用的企业级硬件防火墙Netfilter架构,提出了基于动态深度检测的自适应防火墙总体的体系结构,将状态检测和应用防火墙技术结合在一起,采用L7深层过滤技术,应用C语言的编写,把整个体系结构进行了实现。 相似文献
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教育公平是社会公平的重要组成部分。电大远程开放教育体现了教育公平的基本价值取向,是实现教育公平的重要渠道。为发展电大远程开放教育、推进教育公平,应加强国家信息网络基础设施和网络教学资源建设,加快电大公共服务体系建设以及推进电大教学资源平台建设。 相似文献
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网络交往及其对高校思想政治教育工作的正负面效应 总被引：3，自引：0，他引：3
网络在全球化进程中具有十分重要的作用,我们应当从马克思主义交往理论的高度认识网络交往是当代大学生的一种存在方式,理性分析网络信息的传播给高校思想政治教育工作带来的正负面效应,学会因势利导,利用网络加强大学生的思想政治教育工作。 相似文献
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黄静 《青海师范大学学报(哲学社会科学版)》2004,(1):105-108
素质教育是当前我国教育工作改革发展的重要内容。本文从分析外语教育是素质教育的重要内容入手，提出应充分认识和树立现代外语教学理念，并从发挥教与学的主体性等方面做好当前的大学外语教学，从而充分体现我国实施素质教育的要求。 相似文献
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浅析无机化学中的化学平衡及其应用 总被引：1，自引：0，他引：1
化学平衡内容在无机化学课程中,涉及诸多章节,占较大篇幅。正确理解平衡概念和掌握相关计算技巧,在无机化学教学中至关重要,它会影响到本课程及后续课程的学习。由于学习的阶段性,大多数无机化学教材对这部分内容分章节介绍,学生难以将有关内容进行联系融合,学习有难度。本文将无机化学中有关化学平衡问题进行浅析、综合,目的是使看似复杂的问题简单化,使学生对该内容更易理解、学习和掌握。 相似文献
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林恬伊 《Journal of Zhangzhou Technical Institute》2012,(1):105-108
网络公共事件是一把双刃剑,在促进社会管理进步的同时,也会带来负面效应,清醒认识网络公共事件负面效应的成因,并采取相应的对策,对于提高政府和民众理性认识网络公共事件,提升对网络公共事件的管理水平具有重大的现实意义。 相似文献
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精品课网络教学系统建设的研究与实践 总被引：1，自引：0，他引：1
精品课程建设是提高教学质量的重要手段.而基于网络的多媒体教学系统又是精品课程建设非常重要的环节.借助网络进行教学资源建设、辅助教学,是现代教学方式区别于传统教学方式的重要方面.本文提出了面向精品课程资源整合与信息发布的网络教学系统的研究方案.用以辅助和延伸课堂教学,提高教学质量,从而达到现代化精品课程建设的要求. 相似文献
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网络课程建设是远程教育的重要组成部分,《Visual Basic程序设计》网络课程建设项目的目标是构建一个编程语言的网络学习平台,以学生为主体,体现自主学习和协作学习为导向,为学生提供完善的网络课程学习模式。《Visual Basic程序设计》网络课程基于AsP开发,提供了丰富的课程内容,界面简捷,操作容易,并在实际教学应用中取得了较好的效果。 相似文献
15.
郑斯日古楞 《北京工业职业技术学院学报》2008,7(2):19-23
随着因特网的快速发展,如今网络已经成为生活中不可或缺的一部份,而如何维持网络的稳定性和速度就成为网络管理的重要课题。本研究着眼于设计一套简易的查询系统来辅助网管人员了解网络的情况,一般用户也可用此系统观察目前使用的网络环境质量。 相似文献
16.
Xi-ping Zhang Han-qing Chen Fang Liu Jie Zhang 《Journal of Zhejiang University. Science. B》2009,10(7):493-498
During the development and progression of severe acute pancreatitis (SAP), conspicuous immune dysregulation develops, which is mainly manifested as excessive immune response in the early stage and immunosuppression in the late stage.This process involves complex changes in a variety of immune molecules and cells, such as cytokines, complements, lymphocytes,and leukocytes. With the gradual deepening of studies on the development and progression of SAP, the role of immune dysregulation in the pathogenesis of SAP has attracted more and more attention. In this article, we review the advances in research on the immune dysregulation in SAP and the immunotherapy of this disease through exploring the formation of excessive immune response and immune suppression as well as their mutual transformation. 相似文献
17.
苏毅苗 《重庆第二师范学院学报》2007,20(6):81-84
网络教学是信息化条件下多媒体教学的有力手段,是改革传统音乐教学模式的一次有益尝试.中国音乐史课程由于其内容繁多、关系复杂,学生学习、理解和记忆的难度较大.运用多媒体网络教学,能够直观、形象、科学地组织中国音乐史的各种素材,引导相关人员针对性、系统性的理解和学习,提高学习和科研的效率.开发中国音乐史多媒体数据库,是开展中国音乐史网络教学的基础.不仅可提供丰富的网络教学与科研资源,而且是音乐学科网络教学资源的重要组成部分.文章分析了高校中国音乐史多媒体数据库的建设目标,提出了具体的实现方法. 相似文献
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理想信念教育是思想政治教育的重要组成部分。本文针对新形势下网络信息对大学生理想信念的负面影响，阐明加强大学生理想信念教育的必要性及其主要对策。 相似文献
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医患沟通是医学生培养的重要内容。文章为了了解某医科院校医学本科生医患沟通课程现状,通过自行设计的调查问卷,对某医科院校医学专业大一至大五的本科生进行随机调查,并以此为依据探讨医学本科生医患沟通能力的发展策略。 相似文献