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1.
This study investigated protein kinase activation and gene expression of angiogenic factors in response to low-load resistance exercise with or without blood flow restriction (BFR). In a repeated measures cross-over design, six males performed four sets of bilateral knee extension exercise at 20% 1RM (reps per set?=?30:15:15:continued to fatigue) with BFR (110?mmHg) and without (CON). Muscle biopsies were obtained from the vastus lateralis before, 2 and 4?h post-exercise. mRNA expression was determined using real-time RT–PCR. Protein phosphorylation/expression was determined using Western blot. p38MAPK phosphorylation was greater (p?=?0.05) at 2?h following BFR (1.3?±?0.8) compared to CON (0.4?±?0.3). AMPK phosphorylation remained unchanged. PGC-1α mRNA expression increased at 2?h (5.9?±?1.3 vs. 2.1?±?0.8; p?=?0.03) and 4?h (3.2?±?0.8 vs. 1.5?±?0.4; p?=?0.03) following BFR exercise with no change in CON. PGC-1α protein expression did not change following either exercise. BFR exercise enhanced mRNA expression of vascular endothelial growth factor (VEGF) at 2?h (5.2?±?2.8 vs 1.7?±?1.1; p?=?.02) and 4?h (6.8?±?4.9 vs. 2.5?±?2.7; p?=?.01) compared to CON. mRNA expression of VEGF-R2 and hypoxia-inducible factor 1α increased following BFR exercise but only eNOS were enhanced relative to CON. Matrix metalloproteinase-9 mRNA expression was not altered in response to either exercise. Acute low-load resistance exercise with BFR provides a targeted angiogenic response potentially mediated through enhanced ischaemic and shear stress stimuli.  相似文献   

2.
VO2 fluctuations are argued to be an important mechanism underpinning chronic adaptations following interval training. We compared the effect of exercise modality, continuous vs. intermittent realized at a same intensity, on electrical muscular activity, muscular oxygenation and on whole body oxygen uptake. Twelve participants (24?±?5 years; VO2peak: 43?±?6?mL·?min?1·kg?1) performed (i) an incremental test to exhaustion to determine peak work rate (WRpeak); two randomized isocaloric exercises at 70%WRpeak; (ii) 1 bout of 30 min; (iii) 30 bouts of 1?min work intercepted with 1?min passive recovery. For electromyography, only the CON exercise showed change for the vastus lateralis root-mean-square (+6.4?±?5.1%, P?P?vs. 2.32?±?1.21?mM, respectively, for the CON and INT, P?vs. 356?±?301?sec, respectively, for the CON and INT, P?相似文献   

3.
Fatigue represents a reduction in the capability of muscle to generate force. The aim of the present study was to establish the effects of exercise that simulates the work rate of competitive soccer players on the strength of the knee extensors and knee flexors. Thirteen amateur soccer players (age 23.3±3.9 years, height 1.78±0.05?m, body mass 74.8±3.6?kg; mean±s) were tested during the 2000–2001 soccer season. Muscle strength of the quadriceps and hamstrings was measured on an isokinetic dynamometer. A 90?min soccer-specific intermittent exercise protocol, incorporating a 15?min half-time intermission, was developed to provide fatiguing exercise corresponding in work rate to a game of soccer. The exercise protocol, performed on a programmable motorized treadmill, consisted of the different intensities observed during soccer match-play (e.g. walking, jogging, running, sprinting). Muscle strength was assessed before exercise, at half-time and immediately after exercise. A repeated-measures analysis of variance showed significant reductions (P?<0.001) in peak torque for both the quadriceps and hamstrings at all angular velocities (concentric: 1.05, 2.09, 5.23 rad?·?s?1; eccentric: 2.09 rad?·?s?1). The peak torque of the knee extensors (KE) and knee flexors (KF) was greater before exercise [KE: 232±37, 182±34, 129±27, 219±41?N?·?m at 1.05, 2.09 and 5.23 rad?·?s?1 (concentric) and 2.09 rad?·?s?1 (eccentric), respectively; KF: 126±20, 112±19, 101±16, 137±23?N?·?m] than at half-time (KE: 209±45, 177±35, 125±36, 214±43?N?·?m; KF: 114±31, 102±20, 92±15, 125±25?N?·?m) and greater at half-time than after exercise (KE: 196±43, 167±35, 118±24, 204±43?N?·?m; KF: 104±25, 95±21, 87±13, 114±27?N?·?m). For the hamstrings?:?quadriceps ratio, significant changes were found (P?<0.05) for both legs, the ratio being greater before than after exercise. For fast?:?slow speed and left?:?right ratios, no significant changes were found. We conclude that there is a progressive reduction in muscle strength that applies across a range of functional characteristics during exercise that mimics the work rate in soccer.  相似文献   

4.
This study investigated the effect of a single session of resistance exercise on postprandial lipaemia. Eleven healthy normolipidaemic men with a mean age of 23 (standard error = 1.4) years performed two trials at least 1 week apart in a counterbalanced randomized design. In each trial, participants consumed a test meal (1.2?g fat, 1.1?g carbohydrate, 0.2?g protein and 68 kJ?·?kg?1 body mass) between 08.00 and 09.00?h following a 12?h fast. The afternoon before one trial, the participants performed an 88?min bout of resistance exercise. Before the other trial, the participants were inactive (control trial). Resistance exercise was performed using free weights and included four sets of 10 repetitions of each of 11 exercises. Sets were performed at 80% of 10-repetition maximum with a 2?min work and rest interval. Venous blood samples were obtained in the fasted state and at intervals for 6?h postprandially. Fasting plasma triacylglycerol (TAG) concentration did not differ significantly between control (1.03?±?0.13?mmol?·?l?1) and exercise (0.94?±?0.09?mmol?·?l?1) trials (mean?± standard error). Similarly, the 6?h total area under the plasma TAG concentration versus time curve did not differ significantly between the control (9.84?±?1.40?mmol?·?l?1?·?6?h?1) and exercise (9.38?±?1.12?mmol?·?l?1?·?6?h?1) trials. These findings suggest that a single session of resistance exercise does not reduce postprandial lipaemia.  相似文献   

5.
The effectiveness of a nap as a recovery strategy for endurance exercise is unknown and therefore the present study investigated the effect of napping on endurance exercise performance. Eleven trained male runners completed this randomised crossover study. On two occasions, runners completed treadmill running for 30?min at 75% ?O2max in the morning, returning that evening to run for 20?min at 60% ?O2max, and then to exhaustion at 90% ?O2max. On one trial, runners had an afternoon nap approximately 90?min before the evening exercise (NAP) whilst on the other, runners did not (CON). All runners napped (20?±?10?min), but time to exhaustion (TTE) was not improved in all runners (NAP 596?±?148?s vs. CON 589?±?216?s, P?=?.83). Runners that improved TTE after the nap slept less at night than those that did not improve TTE (night-time sleep 6.4?±?0.7?h vs. 7.5?±?0.4?h, P?r2 ? =??0.76, P?=?.001). In runners that improved TTE, ratings of perceived exertion (RPE) were lower during the TTE on NAP than CON compared to runners that did not improve (?0.4?±?0.6 vs. 0?±?0, P?=?.05). Reduced exercising sense of effort (RPE) may account for the improved TTE after the nap. In conclusion, a short afternoon nap improves endurance performance in runners that obtain less than 7?h night-time sleep.  相似文献   

6.
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7.
Acute ingestion of ketone salts induces nutritional ketosis by elevating β-hydroxybutyrate (βHB), but few studies have examined the metabolic effects of ingestion prior to exercise. Nineteen trained cyclists (12 male, 7 female) undertook graded exercise (8 min each at ～30%, 40%, 50%, 60%, 70%, and 80% VO2peak) on a cycle ergometer on two occasions separated by either 7 or 14 days. Trials included ingestion of boluses of either (i) plain water (3.8?mL?kg?body mass?1) (CON) or (ii) βHB salts (0.38?g?kg?body mass?1) in plain water (3.8?mL?kg body mass?1) (KET), at both 60 min and 15 min prior to exercise. During KET, plasma [βHB] increased to 0.33?±?0.16?mM prior to exercise and 0.44?±?0.15?mM at the end of exercise (both p?.05). Plasma glucose was 0.44?±?0.27?mM lower (p?.01) 30?min after ingestion of KET and remained ～0.2?mM lower throughout exercise compared to CON (p?.001). Respiratory exchange ratio (RER) was higher during KET compared to CON (p?.001) and 0.03–0.04 higher from 30%VO2peak to 60%VO2peak (all p?.05). No differences in plasma lactate, rate of perceived exertion, or gross or delta efficiency were observed between trials. Gastrointestinal symptoms were reported in 13 out of 19 participants during KET. Acute ingestion of βHB salts induces nutritional ketosis and alters the metabolic response to exercise in trained cyclists. Elevated RER during KET may be indicative of increased ketone body oxidation during exercise, but at the plasma βHB concentrations achieved, ingestion of βHB salts does not affect lactate appearance, perceived exertion, or muscular efficiency.  相似文献   

8.
To adhere to the principle of “exercise specificity” exercise testing should be completed using the same physical activity that is performed during exercise training. The present study was designed to assess whether aerobic step exercisers have a greater maximal oxygen consumption (max VO2) when tested using an activity specific, maximal step exercise test (SET; arms and legs) versus a maximal running test (legs only). Female aerobic step exercisers (N=18; 20.7 ± 1.5 years) performed three maximal graded exercise tests (GXTs): 2 SETs; 1 treadmill test (TMT). The SET consisted of six 3-min progressive stages of alternate lead, basic step, basic step with biceps curls, knee raise with pull-down, repeater knee with pull-down, lateral lunge with pull-down, and side squat with shoulder presses. Stepping rate was 32 steps· min?1 on an 8-in (20.32 cm) step for stages 1–3, and a 10-in (25.4 cm) step for stages 4–6. Submaximal and maximal heart rate (HR) and oxygen consumption (VO2) were recorded at the end of each stage. Test–retest reliability for the first five stages of the SET ranged from .91 to .97 for HR, and from .84 to .96 for VO2. Maximal HR was significantly greater (p =.0001) for the SET (200 ± 6.2 beats·min?1) as compared to the TMT (193 ± 7.9 beats·min?1). No significant difference was found for max VO2 (42.9 ± 8.5, 41.2 ± 5.9 ml·kg?1·min?1, p =.14). The SET was a valid and reliable protocol for assessing responses of these aerobic step exercisers; however, max VO2 from a TMT did not differ significantly from the SET. Conversely, max HR obtained from the criterion TMT was 7 beats·min?1 lower than from the SET. If a training HR for step exercise (arms and legs exercise) is prescribed based on the max HR from treadmill exercise (legs only), then the training HR should be calculated from a TMT max HR that has been increased by 7 beats·min?1 to obtain an intensity of step exercise comparable to that of running.  相似文献   

9.
Mouth rinsing using a carbohydrate (CHO) solution has been suggested to improve physical performance in fasting participants. This study examined the effects of CHO mouth rinsing during Ramadan fasting on running time to exhaustion and on peak treadmill speed (Vpeak). In a counterbalanced crossover design, 18 sub-elite male runners (Age: 21?±?2 years, Weight: 68.1?±?5.7?kg, VO2max: 55.4?±?4.8?ml/kg/min) who observed Ramadan completed a familiarization trial and three experimental trials. The three trials included rinsing and expectorating a 25?mL bolus of either a 7.5% sucrose solution (CHO), a flavour and taste matched placebo solution (PLA) for 10?s, or no rinse (CON). The treatments were performed prior to an incremental treadmill test to exhaustion. Three-day dietary and exercise records were obtained on two occasions and analysed. Anthropometric characteristics were obtained and recorded for all participants. A main effect for mouth rinse on peak velocity (Vpeak) (CHO: 17.6?±?1.5?km/h; PLA: 17.1?±?1.4?km/h; CON: 16.7?±?1.2?km/h; P?ηp2?=?0.49) and time to exhaustion (CHO: 1282.0?±?121.3?s; PLA: 1258.1?±?113.4?s; CON: 1228.7?±?98.5?s; P?=?.002, ηp2?=?0.41) was detected, with CHO significantly higher than PLA (P?P?P?>?.05). Energy availability from dietary analysis, body weight, and fat-free mass did not change during the last two weeks of Ramadan (P?>?.05). This study concludes that carbohydrate mouth rinsing improves running time to exhaustion and peak treadmill speed under Ramadan fasting conditions.  相似文献   

10.
The aim of the present study was to examine the effect of ingesting 75?g of glucose 45?min before the start of a graded exercise test to exhaustion on the determination of the intensity that elicits maximal fat oxidation (Fatmax). Eleven moderately trained individuals ( V?O2max: 58.9±1.0?ml?·?kg?1?·?min?1; mean±sx¯ ), who had fasted overnight, performed two graded exercise tests to exhaustion, one 45?min after ingesting a placebo drink and one 45?min after ingesting 75?g of carbohydrate in the form of glucose. The tests started at 95?W and the workload was increased by 35?W every 3?min. Gas exchange measures and heart rate were recorded throughout exercise. Fat oxidation rates were calculated using stoichiometric equations. Blood samples were collected at rest and at the end of each stage of the test. Maximal fat oxidation rates decreased from 0.46±0.06 to 0.33±0.06?g?·?min?1 when carbohydrate was ingested before the start of exercise (P?<0.01). There was also a decrease in the intensity which elicited maximal fat oxidation (60.1±1.9% vs 52.0±3.4% V?O2max) after carbohydrate ingestion (P?<0.05). Maximal power output was higher in the carbohydrate than in the placebo trial (346±12 vs 332±12?W) (P?<0.05). In conclusion, the ingestion of 75?g of carbohydrate 45?min before the onset of exercise decreased Fatmax by 14%, while the maximal rate of fat oxidation decreased by 28%.  相似文献   

11.
This study compared knee angle-specific neuromuscular adaptations after two low-volume isometric leg press complex training programmes performed at different muscle lengths. Fifteen young males were divided into two groups and trained three times per week for 6 weeks. One group (n?=?8) performed 5–7 sets of 3 s maximum isometric leg press exercise, with 4?min recovery, with knee angle at 85°?±?2° (longer muscle-tendon unit length; L-MTU). The other group (n?=?7) performed the same isometric training at a knee angle of 145°?±?2° (180°?=?full extension; shorter muscle-tendon unit length; S-MTU). During the recovery after each set of isometric exercise, participants performed two CMJ every minute, as a form of complex training. Maximum isometric force (MIF) and rate of force development (RFD) were measured over a wide range of knee angles. Countermovement jump (CMJ) performance and maximum half-squat strength (1RM) were also assessed. Training at S-MTU induced a large increase of MIF (22–58%, p?p?p?=?0.001). In contrast, training at L-MTU, resulted in a moderate and similar (≈12.3%, p?=?0.028) improvement of force at all knee angles. CMJ performance and 1RM were equally increased in both groups after training by 10.4%?±?8.3% and 7.8%?±?4.7% (p?相似文献   

12.
Abstract

Post exercise hypotension (PEH) is primarily attributed to post-exercise vasodilation via central and peripheral mechanisms. However, the specific contribution of metabolic cost during exercise, independent of force production, is less clear. This study aimed to use isolated concentric and eccentric exercise to examine the role of metabolic activity in eliciting PEH, independent of total work. Twelve participants (6 male) completed upper and lower body concentric (CONC), eccentric (ECC), and traditional (TRAD) exercise sessions matched for work (3?×?10 in TRAD and 3?×?20 in CONC and ECC; all at 65% 1RM). Blood pressure was collected at baseline and every 15?min after exercise for 120?min. Brachial blood flow and vascular conductance were also assessed at baseline, immediately after exercise, and every 30?min after exercise. ?O2 was lower during ECC compared to CONC and TRAD (?2.7?mL/Kg/min?±?0.4 and ?2.2?mL/Kg/min?±?0.4, respectively p?<?0.001). CONC augmented the PEH response (Peak ΔMAP ?3.3?mmHg?±?0.9 [mean?±?SE], p?=?0.006) through 75?min of recovery and ECC elicited a post-exercise hypertensive response through 120?min of recovery (Peak ΔMAP +4.5?mmHg?±?0.8, p?<?0.001). CONC and TRAD elicited greater increases in brachial blood flow post exercise than ECC (Peak Δ brachial flow +190.4?mL/min?±?32.3, +202.3?mL/min?±?39.2, and 69.6?mL/min?±?19.8, respectively, p?≤?0.005), while conductance increased immediately post exercise in all conditions and then decreased throughout recovery following ECC (?32.9?mL/min/mmHg?±?9.3, p?=?0.005). These data suggest that more metabolically demanding concentric exercise augments PEH compared to work-matched eccentric exercise.  相似文献   

13.
Many physically active individuals have undertaken intermittent fasting to reduce their daily caloric intake. However, abstaining from meals for a specific length of time may lead to the acute disturbance of highly carbohydrate-dependent exercise performance. The purpose of this study was to observe the effect of 10 days of intermittent fasting on high-intensity type exercises, Wingate anaerobic (WT) and prolonged high-intensity time-to-exhaustion (HIT) cycling test. Twenty participants were randomised into an intermittent fasting (FAS) and a control group (CON). One day after baseline data collection on Day-0 where participants consumed their recommended daily caloric intake (FAS?=?2500?±?143?kcal?day?1; CON?=?2492?±?20?kcal?day?1) served over a course of five meals, the FAS group consumed only four meals where 40% was restricted by the omission of lunch (FAS?=?1500?±?55?kcal?day?1). This diet was then continued for 10 days. Data on exercise performance and other dependent variables were collected on Day-2, -4, -6, -8 and -10. A reduction in WT power in the FAS group was observed on Day-2 (821.74?±?66.07?W) compared to Day-0 (847.63?±?95.94?W) with a moderate effect size (p?p?p?相似文献   

14.
This study examined the effect of hypoxia on growth hormone (GH) release during an acute bout of high-intensity, low-volume resistance exercise. Using a single-blinded, randomised crossover design, 16 resistance-trained males completed two resistance exercise sessions in normobaric hypoxia (HYP; inspiratory oxygen fraction, (FiO2) 0.12, arterial oxygen saturation (SpO2) 82?±?2%) and normoxia (NOR; FiO2 0.21, SpO2 98?±?0%). Each session consisted of five sets of three repetitions of 45° leg press and bench press at 85% of one repetition maximum. Heart rate, SpO2, and electromyographic activity (EMG) of the vastus lateralis muscle were measured throughout the protocol. Serum lactate and GH levels were determined pre-exposure, and at 5, 15, 30 and 60?min post-exercise. Differences in mean and integrated EMG between HYP and NOR treatments were unclear. However, there was an important increase in the peak levels and area under the curve of both lactate (HYP 5.8?±?1.8 v NOR 3.9?±?1.1?mmol.L?1 and HYP 138.7?±?33.1 v NOR 105.8?±?20.8?min.mmol.L?1) and GH (HYP 4.4?±?3.1 v NOR 2.1?±?2.5?ng.mL?1 and HYP 117.7?±?86.9 v NOR 72.9?±?85.3?min.ng.mL?1) in response to HYP. These results suggest that performing high-intensity resistance exercise in a hypoxic environment may provide a beneficial endocrine response without compromising the neuromuscular activation required for maximal strength development.  相似文献   

15.
This study examined the effects of different work?–?rest durations during 40?min intermittent treadmill exercise and subsequent running performance. Eight males (mean?±?s: age 24.3?±?2.0 years, body mass 79.4?±?7.0?kg, height 1.77?±?0.05?m) undertook intermittent exercise involving repeated sprints at 120% of the speed at which maximal oxygen uptake (v-[Vdot]O2max) was attained with passive recovery between each one. The work?–?rest ratio was constant at 1:1.5 with trials involving short (6:9?s), medium (12:18?s) or long (24:36?s) work?–?rest durations. Each trial was followed by a performance run to volitional exhaustion at 150% v-[Vdot]O2max. After 40?min, mean exercise intensity was greater during the long (68.4?±?9.3%) than the short work?–?rest trial (54.9?±?8.1% [Vdot]O2max; P?<?0.05). Blood lactate concentration at 10?min was higher in the long and medium than in the short work?–?rest trial (6.1?±?0.8, 5.2?±?0.9, 4.5?±?1.3?mmol?·?l?1, respectively; P?<?0.05). The respiratory exchange ratio was consistently higher during the long than during the medium and short work?–?rest trials (P <?0.05). Plasma glucose concentration was higher in the long and medium than in the short work?–?rest trial after 40?min of exercise (5.6?±?0.1, 6.6?±?0.2 and 5.3?±?0.5?mmol?·?l?1, respectively; P?<?0.05). No differences were observed between trials for performance time (72.7?±?14.9, 63.2?±?13.2, 57.6?±?13.5?s for the short, medium and long work?–?rest trial, respectively; P = 0.17), although a relationship between performance time and 40?min plasma glucose was observed (P?<?0.05). The results show that 40?min of intermittent exercise involving long and medium work?–?rest durations elicits greater physiological strain and carbohydrate utilization than the same amount of intermittent exercise undertaken with a short work?–?rest duration.  相似文献   

16.
Outdoor exercise often proceeds in rainy conditions. However, the cooling effects of rain on human physiological responses have not been systematically studied in hot conditions. The present study determined physiological and metabolic responses using a climatic chamber that can precisely simulate hot, rainy conditions. Eleven healthy men ran on a treadmill at an intensity of 70% VO2max for 30 min in the climatic chamber at an ambient temperature of 33°C in the presence (RAIN) or absence (CON) of 30 mm · h?1 of precipitation and a headwind equal to the running velocity of 3.15 ± 0.19 m · s?1. Oesophageal temperature, mean skin temperature, heart rate, rating of perceived exertion, blood parameters, volume of expired air and sweat loss were measured. Oesophageal and mean skin temperatures were significantly lower from 5 to 30 min, and heart rate was significantly lower from 20 to 30 min in RAIN than in CON (P < 0.05 for all). Plasma lactate and epinephrine concentrations (30 min) and sweat loss were significantly lower (P < 0.05) in RAIN compared with CON. Rain appears to influence physiological and metabolic responses to exercise in heat such that heat-induced strain might be reduced.  相似文献   

17.
This investigation examined the oxidative stress (F2-Isoprostane; F2-IsoP) and inflammatory (interleukin-6; IL-6) responses to repeat-sprint training in hypoxia (RSH). Ten trained male team sport athletes performed 3(sets)*9(repetitions)*5?s cycling sprints in simulated altitude (3000?m) and sea-level conditions. Mean and peak sprint power output (MPO and PPO) were recorded, and blood samples were collected pre-exercise, and again at 8 and 60?min post-exercise. Both MPO and PPO were significantly reduced in hypoxia (compared to sea-level) in the second (MPO: 855?±?89 vs. 739?±?95?W, p?=?.006; PPO: 1024?±?114 vs. 895?±?112?W, p?=?.010) and third (MPO: 819?±?105 vs. 686?±?83?W, p?=?.008; PPO: 985?±?125 vs. 834?±?99?W, p?=?.008) sets, respectively. IL-6 was significantly increased from pre- to 1?h post-exercise in both hypoxia (0.7?±?0.2 vs. 2.4?±?1.4?pg/mL, p?=?.004) and sea-level conditions (0.7?±?0.2 vs. 1.6?±?0.3?pg/mL, p?d?=?0.80) suggesting higher IL-6 levels of post-hypoxia. F2-IsoP was significantly lower 1?h post-exercise in both the hypoxic (p?=?.005) and sea-level (p?=?.002) conditions, with no differences between trials. While hypoxia can impact on exercise intensity and may result in greater post-exercise inflammation, it appears to have little effect on oxidative stress. These results indicate that team sport organisations with ready access to hypoxic training facilities could confidently administer RSH without significantly increasing the post-exercise inflammatory or oxidative stress response.  相似文献   

18.
The aim of the present study was to evaluate the effects of a 12-week home-based strength, explosive and plyometric (SEP) training on the cost of running (Cr) in well-trained ultra-marathoners and to assess the main mechanical parameters affecting changes in Cr. Twenty-five male runners (38.2?±?7.1 years; body mass index: 23.0?±?1.1?kg·m?2; V˙O2max: 55.4?±?4.0 mlO2·kg?1·min?1) were divided into an exercise (EG?=?13) and control group (CG?=?12). Before and after a 12-week SEP training, Cr, spring-mass model parameters at four speeds (8, 10, 12, 14?km·h?1) were calculated and maximal muscle power (MMP) of the lower limbs was measured. In EG, Cr decreased significantly (p?<?.05) at all tested running speeds (?6.4?±?6.5% at 8?km·h?1; ?3.5?±?5.3% at 10?km·h?1; ?4.0?±?5.5% at 12?km·h?1; ?3.2?±?4.5% at 14?km·h?1), contact time (tc) increased at 8, 10 and 12?km·h?1 by mean +4.4?±?0.1% and ta decreased by ?25.6?±?0.1% at 8?km·h?1 (p?<?.05). Further, inverse relationships between changes in Cr and MMP at 10 (p?=?.013; r?=??0.67) and 12?km·h?1 (p?<?.001; r?=??0.86) were shown. Conversely, no differences were detected in the CG in any of the studied parameters. Thus, 12-week SEP training programme lower the Cr in well-trained ultra-marathoners at submaximal speeds. Increased tc and an inverse relationship between changes in Cr and changes in MMP could be in part explain the decreased Cr. Thus, adding at least three sessions per week of SEP exercises in the normal endurance-training programme may decrease the Cr.  相似文献   

19.
The aim of this study was to compare the impact of continuous (CON) and intermittent (INT) heat acclimation protocols on repeat-sprint performance, and to also assess the degree of performance decay following acclimation. Using a pair-matched, between subjects design, 16 trained male team sport athletes were allocated to either INT (8 sessions over 15 days) or CON acclimation (8 sessions over 8 days) groups. Participants performed a heat tolerance test (HTT) involving 60-min of repeat-sprint cycling with a 10-min half time break (in 35.3?±?0.7°C, 60.1?±?4.0%; RH) two days pre- (pre-HTT) and post-acclimation (post-HTT1). Decay was investigated with two further HTT's completed over the next two weeks (post-HTT2 and post-HTT3). Results showed the post-HTT1 performance variables [mean power (pre-HTT; INT?=?1002.07?±?173.74, CON?=?1057.10?±?180.07 / post-HTT1; INT?=?1097.11?±?186.85, CON?=?1163.77?±?184.65 W), mean power (W.kg?1), total work (kJ) and work (J.kg?1)] were greater than pre-HHT (p?p?相似文献   

20.
Strenuous physical exercise of the limb muscles commonly results in damage, especially when that exercise is intense, prolonged and includes eccentric contractions. Many factors contribute to exercise-induced muscle injury and the mechanism is likely to differ with the type of exercise. Competitive sports players are highly susceptible to this type of injury. AM3 is an orally administered immunomodulator that reduces the synthesis of proinflammatory cytokines and normalizes defective cellular immune fractions. The ability of AM3 to prevent chronic muscle injury following strenuous exercise characterized by eccentric muscle contraction was evaluated in a double-blind and randomized pilot study. Fourteen professional male volleyball players from the First Division of the Spanish Volleyball League volunteered to take part. The participants were randomized to receive either placebo (n?=?7) or AM3 (n?=?7). The physical characteristics (mean±s) of the placebo group were as follows: age 25.7±2.1 years, body mass 87.2±4.1?kg, height 1.89±0.07?m, maximal oxygen uptake 65.3±4.2?ml?·?kg?1?·?min?1. Those of the AM3 group were as follows: age 26.1±1.9 years, body mass 85.8±6.1?kg, height 1.91±0.07?m, maximal oxygen uptake 64.6±4.5?ml?·?kg?1?·?min?1. All participants were evaluated for biochemical indices of muscle damage, including concentrations of aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, creatine kinase (CK) and its MB fraction (CK-MB), myoglobin, lactate dehydrogenase, urea, creatinine and γ-glutamyltranspeptidase, both before and 30 days after treatment (over the peak of the competitive season). In the placebo group, competitive exercise (i.e. volleyball) was accompanied by significant increases in creatine kinase (494±51 to 560±53?IU?·?l?1, P?<?0.05) and myoglobin (76.8±2.9 to 83.9±3.1?μg?·?l?1, P?<?0.05); aspartate aminotransferase (30.8±3.0 to 31.1±2.9?IU?·?l?1) and lactate dehydrogenase (380±31 to 376±29?IU?·?l?1) were relatively unchanged after the 30 days maximum effort. AM3 not only inhibited these changes, it led to a decrease from baseline serum concentrations of creatine kinase (503±49 to 316±37?IU?·?l?1, P?<?0.05) and myoglobin (80.1±3.2 to 44.1±2.6?IU?·?l?1, P?<?0.05), as well as aspartate aminotransferase (31.1±3.3 to 26.1±2.7?IU?·?l?1, P?<?0.05) and lactate dehydrogenase (368±34 to 310±3?IU?·?l?1, P?<?0.05). The concentration of CK-MB was also significantly decreased from baseline with AM3 treatment (11.6±1.2 to 5.0±0.7?IU?·?l?1, P?<?0.05), but not with placebo (11.4±1.1 to 10.8±1.4?IU?·?l?1). In conclusion, the use of immunomodulators, such as AM3, by elite sportspersons during competition significantly reduces serum concentrations of proteins associated with muscle damage.  相似文献   

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