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1.
Abstract

Nitroglycerin induces the so-called second window of protection (SWOP), which alleviates myocardial damage and stunning after ischaemia/reperfusion. To determine whether myocardial performance during exercise is improved in the second window of protection, we studied the haemodynamic responses of 12 trained and 11 sedentary individuals during a sequence of maximal tests on a cycle ergometer. A baseline test (basal test) was followed by a second effort performed during the second window of protection (exercise-SWOP test). Haemodynamics was also evaluated after pharmacologically induced SWOP 48 h after transdermal administration of 10 mg of nitroglycerin (pharmacologically induced SWOP test). The exercise-SWOP and pharmacologically induced SWOP tests were separated by a 1-week washout period. Endothelial-dependent vasodilatation after nitroglycerin pre-treatment was also assessed in five sedentary individuals to determine whether nitrate donors could affect vascular function. We found that nitroglycerin pre-treatment did not induce any improvement in haemodynamics in either trained or sedentary individuals, since maximum values of workload, heart rate, stroke volume, cardiac output, myocardial contractility, and double product were similar between the exercise-SWOP and pharmacologically induced SWOP tests in both groups. Furthermore, nitroglycerin pre-treatment did not alter flow-mediated dilation during pharmacologically induced SWOP. Although nitroglycerin pre-treatment alleviates post-ischaemic myocardial stunning, our results suggest that it does not affect the myocardial performance of healthy individuals during exercise performed in the second window of protection, independently of the training status of the individuals. Moreover, nitroglycerin pre-treatment does not ameliorate endothelial function.  相似文献   

2.
Abstract

To assess the effect of cold water immersion and active recovery on thermoregulation and repeat cycling performance in the heat, ten well-trained male cyclists completed five trials, each separated by one week. Each trial consisted of a 30-min exercise task, one of five 15-min recoveries (intermittent cold water immersion in 10°C, 15°C and 20°C water, continuous cold water immersion in 20°C water or active recovery), followed by 40 min passive recovery, before repeating the 30-min exercise task. Recovery strategy effectiveness was assessed via changes in total work in the second exercise task compared with that in the first. Following active recovery, a mean 4.1% (s = 1.8) less total work (P = 0.00) was completed in the second than in the first exercise task. However, no significant differences in total work were observed between any of the cold water immersion protocols. Core and skin temperature, blood lactate concentration, heart rate, rating of thermal sensation, and rating of perceived exertion were recorded. During both exercise tasks there were no significant differences in blood lactate concentration between interventions; however, following active recovery blood lactate concentration was significantly lower (P < 0.05; 2.0 ± 0.8 mmol · l?1) compared with all cold water immersion protocols. All cold water immersion protocols were effective in reducing thermal strain and were more effective in maintaining subsequent high-intensity cycling performance than active recovery.  相似文献   

3.
We investigated the oxygen-conserving potential of the human diving response by comparing trained breath-hold divers (BHDs) to non-divers (NDs) during simulated dynamic breath-holding (BH). Changes in haemodynamics [heart rate (HR), stroke volume (SV), cardiac output (CO)] and peripheral muscle oxygenation [oxyhaemoglobin ([HbO2]), deoxyhaemoglobin ([HHb]), total haemoglobin ([tHb]), tissue saturation index (TSI)] and peripheral oxygen saturation (SpO2) were continuously recorded during simulated dynamic BH. BHDs showed a breaking point in HR kinetics at mid-BH immediately preceding a more pronounced drop in HR (?0.86 bpm.%?1) while HR kinetics in NDs steadily decreased throughout BH (?0.47 bpm.%?1). By contrast, SV remained unchanged during BH in both groups (all P > 0.05). Near-infrared spectroscopy (NIRS) results (mean ± SD) expressed as percentage changes from the initial values showed a lower [HHb] increase for BHDs than for NDs at the cessation of BH (+24.0 ± 10.1 vs. +39.2 ± 9.6%, respectively; P < 0.05). As a result, BHDs showed a [tHb] drop that NDs did not at the end of BH (?7.3 ± 3.2 vs. ?3.0 ± 4.7%, respectively; P < 0.05). The most striking finding of the present study was that BHDs presented an increase in oxygen-conserving efficiency due to substantial shifts in both cardiac and peripheral haemodynamics during simulated BH. In addition, the kinetic-based approach we used provides further credence to the concept of an “oxygen-conserving breaking point” in the human diving response.  相似文献   

4.
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5.
Abstract

The purpose of this study was to investigate the acute effect of cigarette smoking on cardiac autonomic function in young adult smokers during dynamic exercise. Fourteen healthy young smokers (21.4 ± 3.4 years) performed peak and submaximal exercise protocols under control and smoking conditions. Resting and submaximal beat-to-beat R-R series were recorded and spectrally decomposed using the fast Fourier transformation. Smoking resulted in a significant decrease in work time, [Vdot]O2peak and peak O2 pulse (P < 0.05). Heart rate increased at rest and during submaximal exercise after smoking (P < 0.05). The raw high frequency and low frequency power were significantly reduced by smoking, both at rest and during exercise (P < 0.05). The low to high frequency ratio was higher after smoking (P < 0.05). The normalised low frequency power was also significantly increased by smoking, but only at rest (P < 0.05). These data demonstrate that the tachycardic effect elicited by smoking is accompanied by acute changes in heart rate spectral components both at rest and during exercise. Therefore, the cardiac autonomic control is altered by smoking not only at rest, but also during exercise, resulting in reduced vagal modulation and increased sympathetic dominance.  相似文献   

6.
The purpose of this study was to identify the influence of cryotherapy on lower extremity running biomechanics. Twenty-six healthy male volunteers were randomised into two intervention groups: cold water (cold water at ~11°C) or tepid water (tepid water at ~26°C). They were required to run at 4.0 ± 0.2 m · s?1 before and after they underwent water immersion for 20 min. Differences between pre- and post-intervention were used to compare the influence of water intervention during running. Peak joint angles, peak joint moments, peak ground reaction forces (GRF) and contact time (CT) were calculated using three-dimensional gait analysis. Independent t-tests were applied with a significant alpha level set at 0.05. Decreased peak propulsive and vertical GRF, decreased plantarflexion moments, increased hip flexion angle and longer CT were observed following cold water immersion. Although cold water immersion (cryotherapy) affected the running movement, none of the alterations have been related to running biomechanical patterns associated with injuries. Therefore, our results indicated that cold water immersion appears safe prior to running activities.  相似文献   

7.
Abstract

To evaluate the effectiveness of recovery strategies on physical performance during a 3-day tournament style basketball competition, 29 male players (mean age 19.1 years, s = 2.1; height 1.84 m, s = 0.34; body mass 88.5 kg, s = 14.7) were assigned to one of three treatment groups: carbohydrate + stretching (7.7 g · kg ?1 · day ?1, s = 1.7; ‘n = 9), cold water immersion (11°C, 5 × 1; n = 10) or full leg compression garments (18 mmHg, ～18 h; n = 10). Effects of the recovery strategies on pre–post tournament performance tests were expressed as the mean change (% ± standard deviation of the change score). Changes and differences were standardized for accumulated game time, assessed against the smallest worthwhile change for each test, and reported qualitatively. Accumulated fatigue was evident over the tournament with small to moderate impairments in performance tests. Sprint and agility performance decreased by 0.7% (s = 1.3) and 2.0% (s = 1.9) respectively. Vertical jump decreased substantially after the first day for all treatments, and remained suppressed post-tournament. Cold water immersion was substantially better in maintaining 20-m acceleration with only a 0.5% (s = 1.4) reduction in 20-m time after 3 days compared with a 3.2% (s = 1.6) reduction for compression. Cold water immersion (?1.4%, s = 1.7) and compression (?1.5%, s = 1.7) showed similar substantial benefits in maintaining line-drill performance over the tournament, whereas carbohydrate + stretching elicited a 0.4% (s = 1.8) reduction. Sit-and-reach flexibility decreased for all groups, although cold water immersion resulted in the smallest reduction in flexibility. Basketball tournament play elicited small to moderate impairments in physical test performance. In conclusion, cold water immersion appears to promote better restoration of physical performance measures than carbohydrate + stretching routines and compression garments.  相似文献   

8.
Abstract

In this study, we examined the effect of muscle temperature (T m) on adenosine triphosphate (ATP) and phosphocreatine utilization in single muscle fibres during the development of maximal power output in humans. Six male participants performed a 6-s maximal sprint on a friction-braked cycle ergometer under both normal (T m = 34.3°C, s = 0.6) and elevated (T m = 37.3°C, s = 0.2) muscle temperature conditions. During the elevated condition, muscle temperature of the legs was raised, passively, by hot water immersion followed by wrapping in electrically heated blankets. Muscle biopsies were taken from the vastus lateralis before and immediately after exercise. Freeze-dried single fibres were dissected, characterized according to myosin heavy chain composition, and analysed for ATP and phosphocreatine content. Single fibres were classified as: type I, IIA, IIAX25 (1 – 25% IIX isoform), IIAX50 (26 – 50% IIX), IIAX75 (51 – 75% IIX), or IIAX100 (76 – 100% IIX). Maximal power output and pedal rate were both greater (P < 0.05) during the elevated condition by 258 W (s = 110) and 22 rev · min?1 (s = 6), respectively. In both conditions, phosphocreatine content decreased significantly in all fibre types, with a greater decrease during the elevated condition in type IIA fibres (P < 0.01). Adenosine triphosphate content was also reduced to a greater (P < 0.01) extent in type IIA fibres during the elevated condition. The results of the present study indicate that after passive elevation of muscle temperature, there was a greater decrease in ATP and phosphocreatine content in type IIA fibres than in the normal trial, which contributed to the higher maximal power output.  相似文献   

9.
Abstract

We investigated cardiovascular fitness and haemodynamic responses to maximal cycle ergometer exercise test in children. The participants were a population sample of 425 children (204 girls, 221 boys) aged 6–8 years. Heart rate (HR) and systolic blood pressure (SBP) were measured from the beginning of pre-exercise rest to the end of recovery period. We provided reference values for peak workload and changes in HR and SBP during and after maximal exercise test in girls and boys. Girls had a lower cardiovascular fitness, indicated by peak workload per body weight [mean (2 s) 2.7 (0.9) vs. 3.1 (1.0) W · kg–1, P < 0.001] and lean mass [mean (2 s) 3.5 (0.9) vs. 3.8 (1.0) W· kg–1, P < 0.001] than boys. Plateau or decline in SBP close to the end of the test was found in about third of children and was considered a normal SBP response. Girls had a slower HR decrease within 2 min after the test than boys [mean (2 s) 53 (18) vs. 59 (22) beats · min–1, P < 0.001]. The results are useful for physicians and exercise physiologists to evaluate cardiovascular fitness and haemodynamic responses to exercise in children and to detect children with low exercise tolerance or abnormal haemodynamic responses to exercise.  相似文献   

10.
Abstract

Cardiorespiratory responses to two levels of exercise (133 and 200 W) on a bicycle ergometer were measured in nine subjects before and after a 1‐h outdoor run of 12.8 km completed in ambient temperatures of 20–25° C. After the run, the subjects showed a mean weight loss of 1.49 kg; the laboratory exercises produced higher mean levels of O2 consumption than before the run (1.91 and 2.66 1 min‐1 compared with 1.80 and 2.46 1 min‐1) and higher mean heart rates (141 and 158 beats min‐1 compared with 115 and 140 beats min‐1); and lower levels of stroke volume (83 and 85 ml compared with 109 and 101 ml) and of cardiac output (11.6 and 13.3 1 min‐1 compared with 12.6 and 14.1 1 min‐1). Five subjects were studied in a similar way on a second occasion when they consumed 1.25 1 of a dextrose‐electrolyte solution during the first 45 min of the outdoor run. Differences in the exercise variables measured before and after the outdoor run were now small or insignificant. It is postulated that in the first study uncompensated loss of body water reduced plasma volume and cardiac filling, thus reducing stroke volume and cardiac output. Such changes jeopardize body temperature regulation during exercise.  相似文献   

11.
Abstract

The aim of this study was to assess the effects of cold-water immersion (cryotherapy) on indices of muscle damage following a bout of prolonged intermittent exercise. Twenty males (mean age 22.3 years, s = 3.3; height 1.80 m, s = 0.05; body mass 83.7 kg, s = 11.9) completed a 90-min intermittent shuttle run previously shown to result in marked muscle damage and soreness. After exercise, participants were randomly assigned to either 10 min cold-water immersion (mean 10°C, s = 0.5) or a non-immersion control group. Ratings of perceived soreness, changes in muscular function and efflux of intracellular proteins were monitored before exercise, during treatment, and at regular intervals up to 7 days post-exercise. Exercise resulted in severe muscle soreness, temporary muscular dysfunction, and elevated serum markers of muscle damage, all peaking within 48 h after exercise. Cryotherapy administered immediately after exercise reduced muscle soreness at 1, 24, and 48 h (P < 0.05). Decrements in isometric maximal voluntary contraction of the knee flexors were reduced after cryotherapy treatment at 24 (mean 12%, s x  = 4) and 48 h (mean 3%, s x  = 3) compared with the control group (mean 21%, s x  = 5 and mean 14%, s x  = 5 respectively; P < 0.05). Exercise-induced increases in serum myoglobin concentration and creatine kinase activity peaked at 1 and 24 h, respectively (P < 0.05). Cryotherapy had no effect on the creatine kinase response, but reduced myoglobin 1 h after exercise (P < 0.05). The results suggest that cold-water immersion immediately after prolonged intermittent shuttle running reduces some indices of exercise-induced muscle damage.  相似文献   

12.
Abstract

The purpose of this study was to determine the effects of plyometric exercise on unilateral balance performance. Nine healthy adults performed baseline measurements on the dominant limb that consisted of: a 20-s unilateral stability test on a tilt balance board, where a higher stability index represented deterioration in balance performance; isokinetic plantar flexion torque at 0.52 and 3.14 rad · s?1; muscle soreness in the calf region; and resting plantar flexion angle. Plyometric exercise consisted of 200 counter-movement jumps designed to elicit symptoms of muscle damage, after which baseline measurements were repeated at 30 min, 24, 48, and 72 h. Perceived muscle soreness of the calf region increased significantly following the plyometric exercise protocol (F4,32 = 17.24, P < 0.01). Peak torque was significantly reduced after the plyometric exercise protocol (F4,32 = 7.49, P < 0.05), with greater loss of force at the lower angular velocity (F4,32 = 3.46, P < 0.05), while resting plantar flexion angle was not significantly altered compared with baseline values (P > 0.05). The stability index was significantly increased (F4,32 = 3.10, P < 0.05) above baseline (mean 2.3, s = 0.3) at 24 h (3.3, s = 0.4), after which values recovered. These results indicate that there is a latent impairment of balance performance following a bout of plyometric exercise, which has implications for both the use of skill-based activities and for increased injury risk following high-intensity plyometric training.  相似文献   

13.
Epidemiological studies suggest that prolonged sitting increases all-cause mortality; yet, physiological causes underpinning prolonged sitting remain elusive. We evaluated cardiometabolic function during prolonged sitting (5 h) in 10 adults with and without 30 min of moderate exercise leading up to the sitting. Mean arterial blood pressure (MAP), heart rate (HR) and posterior tibial artery blood velocity were measured at baseline and every hour subsequently. Blood glucose was measured at baseline, 3 and 5 h, with consumption of a caloric beverage at 1 h. Seated MAP and HR values were ~17 mmHg (P < 0.001) and ~4 bpm (P < 0.05) higher for the moderate exercise versus sitting conditions. A ~ 4 cm·s?1 (16%) (P < 0.05) decline in posterior tibial artery blood velocity from prolonged sitting was observed, with no benefit conferred from moderate exercise. Postprandial glucose metabolism was not different between conditions (P > 0.05). We conclude prolonged sitting may be related to decreased posterior tibial artery blood velocity. Moreover, an acute bout of moderate exercise does not seem to attenuate cardiometabolic function during prolonged sitting in healthy, young adults.  相似文献   

14.
The aim of this study was to investigate the effect of two different exercise interventions in the morning on football-specific components of performance in the afternoon under conditions simulating a competition day. In the morning on 3 experimental days, 12 football players (age 24.1?±?5.5 years) completed three different preload interventions that were applied in a counter-balanced order: (1) no intervention (NI); (2) moderate-intensive exercise (MI); and (3) high-intensive exercise (HI). The subjects performed the preload exercises, consisting of a small-sided game and repeated maximal sprints, from 10:00–11:00 a.m. At 3:00 p.m., the Bangsbo test (BT) was applied to examine the effects of the different morning interventions on football-specific endurance capacity. The results showed that the HI led to significantly higher blood-lactate concentrations (moderate to very large effect) and heart rates (very large to extremely large effect) compared to the MI. In addition, there was a significant measurement?×?intervention effect on concentrations of adrenalin and noradrenalin in the urine, which reached higher values immediately after the HI (very large effect) and MI (moderate effect) compared to NI. All effects disappeared by the time of the BT in the afternoon. During all trials, after the preload intervention, reaction time and critical flicker fusion frequency increased significantly compared to the baseline morning values (reaction time: small; critical flicker fusion: trivial to small effect), but no measurement?×?intervention interaction was found. During the BT, the mean total distance covered (trivial to small effect) and the pacing pattern did not differ significantly among the trials despite numerous small individual effects. We conclude that exercise interventions of various intensities in the morning have no general effect on football-specific components of performance in the afternoon despite significant metabolic, endocrinological and cognitive short-term effects. Coaches should consider individual preferences when prescribing competition-day procedures.  相似文献   

15.
The aim of this narrative review was to propose a deterministic model based on a review of previous research documenting the evidence for the associations between average kayak velocity and kinematic variables in sprint kayaking. Literature was reviewed after searching electronic databases using key words ‘kayak,’ ‘biomechanics,’ ‘velocity,’ ‘kinematics,’ and ‘performance.’ Our kinematic deterministic model for sprint kayaking performance shows that the average kayak velocity is determined by kayak stroke displacement and stroke time. Stroke time had the strongest correlation with 200-m race time (r = 0.86, p < 0.001), and stroke rate (inversely proportional to stroke time) was strongly correlated with average horizontal velocity over two consecutive strokes at race pace (r = ? 0.83, p < 0.05). Increased stroke rate via decreased absolute water phase time and increased relative water phase time were indicative of more elite performance. There was no significant relationship between stroke displacement and velocity; however, a large decrease in stroke displacement may be detrimental to performance. Individual characteristics may be responsible for a paddlers’ ability to achieve and sustain a given stroke rate. Coaches should theoretically focus interventions on increasing stroke rate while maintaining stroke displacement; however this hypothesis should be confirmed with prospective studies.  相似文献   

16.
Abstract

The aims of this study were to examine the use of the critical velocity test as a means of predicting 2000-m rowing ergometer performance in female collegiate rowers, and to study the relationship of selected physiological variables on performance times. Thirty-five female collegiate rowers (mean ± s: age 19.3 ± 1.3 years; height 1.70 ± 0.06 m; weight 69.5 ± 7.2 kg) volunteered to participate in the study. Rowers were divided into two categories based on rowing experience: varsity (more than 1 year collegiate experience) and novice (less than 1 year collegiate experience). All rowers performed two continuous graded maximal oxygen consumption tests (familiarization and baseline) to establish maximal oxygen uptake ([Vdot]O2max), peak power output, and power output at ventilatory threshold. Rowers then completed a critical velocity test, consisting of four time-trials at various distances (400 m, 600 m, 800 m, and 1000 m) on two separate days, with 15 min rest between trials. Following the critical velocity test, rowers completed a 2000-m time-trial. Absolute [Vdot]O2max was the strongest predictor of 2000-m performance (r = 0.923) in varsity rowers, with significant correlations also observed for peak power output and critical velocity (r = 0.866 and r = 0.856, respectively). In contrast, critical velocity was the strongest predictor of 2000-m performance in novice rowers (r = 0.733), explaining 54% of the variability in performance. These findings suggest the critical velocity test may be more appropriate for evaluating performance in novice rowers.  相似文献   

17.
Good sleep is critical for optimising recovery and athletic performance. Yet, few studies have investigated how athletes sleep before and during competition. The aim of this study was to determine whether such sleep is poorer than that before a usual training day. Twenty-one male endurance cyclists’ (age: 19.9 ± 1.7 years) sleep/wake behaviour was assessed using wrist activity monitors for 11 nights, including a six-night baseline training phase, three nights before competition and two nights during competition. Cyclists had less sleep on the night before competition (6.5 ± 0.9 h) and during the first night of competition (6.8 ± 0.8 h) than at baseline (7.4 ± 0.6 h). Cyclists also went to bed and woke up earlier during competition than at baseline. Competition schedules and competition itself can disrupt the sleep/wake behaviour of athletes during competition. Future investigations should examine sleep during three stages of competition (i.e. before, during and after competition). This will help coaches develop a greater understanding of how sleep changes during different phases of competition and enable them to plan post-competition training programmes to ensure appropriate rest and recovery is obtained.  相似文献   

18.
This study examined the influence of body composition on temperature and blood flow responses to post-exercise cold water immersion (CWI), hot water immersion (HWI) and control (CON). Twenty-seven male participants were stratified into three groups: 1) low mass and low fat (LM-LF); 2) high mass and low fat (HM-LF); or 3) high mass and high fat (HM-HF). Experimental trials involved a standardised bout of cycling, maintained until core temperature reached 38.5°C. Participants subsequently completed one of three 15-min recovery interventions (CWI, HWI, or CON). Core, skin and muscle temperatures, and limb blood flow were recorded at baseline, post-exercise, and every 30 min following recovery for 240 min. During CON and HWI there were no differences in core or muscle temperature between body composition groups. The rate of fall in core temperature following CWI was greater in the LM-LF (0.03 ± 0.01°C/min) group compared to the HM-HF (0.01 ± 0.001°C/min) group (P = 0.002). Muscle temperature decreased to a greater extent during CWI in the LM-LF and HM-LF groups (8.6 ± 3.0°C) compared with HM-HF (5.1 ± 2.0°C, P < 0.05). Blood flow responses did not differ between groups. Differences in body composition alter the thermal response to post-exercise CWI, which may explain some of the variance in the responses to CWI recovery.  相似文献   

19.
Abstract

The aim of the present study was to determine the effect of a carbohydrate mouthwash on running time-trial performance. On two separate occasions, seven recreationally active males ([Vdot]O2max 57.8 ml · kg?1 · min?1, s = 3.7) completed a preloaded (15 min at 65%[Vdot]O2max) time-trial of 45 min in duration on a motorized treadmill. At 6-min intervals during the preload and time-trial, participants were given either a 6% maltodextrin, 3% lemon juice solution (carbohydrate trial) or a 3% lemon juice placebo mouthwash (placebo trial) in a double-blind, randomized crossover design. Heart rate, oxygen consumption ([Vdot]O2), respiratory exchange ratio (RER), and ratings of perceived exertion (RPE) were measured during the preload, and blood glucose and lactate were measured before and after the preload and time-trial. There were no significant differences in distance covered between trials (carbohydrate: 9333 m, s = 988; placebo: 9309 m, s = 993). Furthermore, there were no significant between-trial differences in heart rate and running speed during the time-trial, or [Vdot]O2, RER or RPE during the preload. Blood lactate and glucose increased as a result of the exercise protocol, with no between-trial differences. In conclusion, there was no positive effect of a carbohydrate mouthwash on running performance of ～1 h duration.  相似文献   

20.
ABSTRACT

The main purpose of this study was to compare the effects of resistance training (RT) performed with different training volumes on phase angle (PhA), body water components, and muscle quality (MQ) in untrained older adult women. A second purpose was to assess the relationship between PhA and MQ. Sixty-two older adult women (68.6 ± 5.0 years, 65.2 ± 13.3 kg, 156.1 ± 6.2 cm) were randomly assigned into one of the three groups: two training groups performed either 1 set (G1S) or 3 sets (G3S), or a control group (CG). Body water components and PhA were estimated by bioelectrical impedance (BIA). MQ was determined by dividing skeletal muscle mass estimated by dual-energy absorptiometry (DXA) by total muscle strength from three exercises. After the intervention period, both training groups demonstrated improvements (P < 0.05) when compared with CON for intracellular water, total body water, PhA, and MQ. These results suggest that RT can improve PhA, body water components, and MQ after 12 weeks of RT in untrained older women, regardless of training volume. Furthermore, changes in MQ were positively correlated with changes in PhA (r = 0.60, P < 0.01).  相似文献   

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