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1.
Asaolu Modupe Fisayo 《Indian journal of clinical biochemistry : IJCB》2007,22(2):93-95
The plasma concentrations of total protein, albumin, immunoglobulins IgG, IgA and IgM and urinary protein were assayed in
250 pregnant Nigerian women with malaria and compared with 250 healthy pregnant women which served as controls. The mean values
of plasma total proteins, albumin, IgG and IgA were significantly lowered (P<0.05) while a slight increase in IgM was observed
in the malaria patients. Urinary proteins value of 23.10±0.50 mg/dl was obtained for the pregnant women with malaria, this
was significantly higher (P<0.05) than that of the controls with the corresponding value of 15.32±0.09 mg/dl. This study has
therefore demonstrated elevations of the urinary and decrease in plasma proteins in gestational malaria. These findings suggest
that the protein profile should be considered in the diagnosis and treatment of malaria. 相似文献
2.
Soma Gupta M. V. R. Reddy B. C. Harinath 《Indian journal of clinical biochemistry : IJCB》2004,19(1):138-141
Lipid peroxidation product, malonaldehyde (MDA) and antioxidants were estimated in plasma and erythrocytes of 34 cases of
oral submucous fibrosis (OSMF) of different grades with equal number of healthy controls to evaluate the association of reactive
oxygen species (ROS) and OSMF. While plasma MDA was found to be significantly higher in patients (3.3±0.4 nmole/ml, P<0.001)
as compared to controls (2.4±0.5 nmole/ml), plasma beta carotene and vitamin E levels were found to be decreased significantly
in patients (81.7±14.3 μg/100 ml, P<0.001; 9.3±0.9 mg/L, P<0.01 respectively) with respect to healthy controls (110±20.8 μg/100
ml and 10.1±1.2 mg/L). The decrease in beta-carotene and vitamin E was found to be more significant in OSMF grade II and III
than in grade I. After 6 weeks of oral administration of beta-carotene and vitamin E, patients showed increase in plasma level
of these two antioxidants along with decrease in MDA level associated with clinical improvement. 相似文献
3.
S. B. Sharma S. Dwivedi K. M. Prabhu Narendra Kumar M. C. Baruah 《Indian journal of clinical biochemistry : IJCB》1999,14(2):245-248
Serum lipid profile, apolipoprotein-B (apo-B), malondialdehyde levels(MDA) and superoxide dismutase (SOD) activity were assessed
in 12 cases of xanthelasma with and without coronary artery disease (CAD)/hypertension (HTN) and results are compared with
healthy controls. Dyslipidemia was found in 65% cases of xanthelasma as compared to 20% healthy controls. Xanthelasma patients
had significantly high malondialdehyde (MDA) levels (p<0.01) and significantly decreased (p<0.05) SOD activity as compared
to controls. Among xanthelasma patients, xanthelasma with CAD/HTN showed higher total cholesterol (236±32.7 vs 188±24.7 mg/dl),
low density lipoprotein cholesterol (157±35.5 vs 113±16 mg/dl) and Apo-B (120.5±9.4 vs 114±19.2 mg/dl) levels as compared
to xanthelasma without CAD/HTN. Results of our study indicate that xanthelasma patients with increased apo-B, MDA and decreased
SOD need cardiovascular monitoring. 相似文献
4.
Rajesh Bhagwat S. P. Joshi Pradeep Salgia Achal Sepaha 《Indian journal of clinical biochemistry : IJCB》1997,12(1):81-85
Lipid abnormalities remain to be a major cause of early mortality in patients with chronic renal failure (CRF). In present
study, 114 (one hundred fourteen) CRF patients without any additional cause of dyslipidemia were divided into groups on the
basis of etiologies of CRF. Blood samples from each group were analyzed for total cholesterol, triglyceride and HDL cholesterol
along with blood urea nitrogen and serum creatinine. 25 healthy individuals without any obvious disease were taken as control.
Patients from all the groups showed a marked hypertriglyceridemia of 232 (SD±77) mg/dl (P<0.001) as compared to control. Levels
of HDL cholesterol were found to be significantly low 20 (±11) mg/dl (p<0.001) in all the groups. LDL cholesterol showed an
increase 104 (±30) mg/dl as compared to control group which is not statistically significant. Present study reveals that,
CRF patients show an uniform dyslipidemia irrespective of etiologies leading to CRF. This dyslipidemia is also independent
of serum creatinine levels. Although, these lipid abnormalities may not solely cause mortality in CRF patients, they may act
as modulators in accelerating atherogenesis which in turn cause early mortality in CRF patients. 相似文献
5.
C. O. Awoyelu J. C. Agharanya O. O. Oguntibeju 《Indian journal of clinical biochemistry : IJCB》2004,19(1):54-56
Ascorbic acid levels in 30 subjects in their third trimester of pregnancy were estimated. Their haematological parameters
(packed cell volume, haemoglobin and mean cell haemoglobin concentration) were also determined. The values were compared with
that of 30 non-pregnant women (control group). The ascorbic acid status of newly born babies using cord blood were determined
along with that of their mothers at delivery. The ascorbic acid level of 0.92±0.37 mg/dl was reported in third trimester.
This value was not significantly (P>0.05) lower than in the control group (1.04±0.4 mg/dl). The result showed that the ascorbic
acid level at delivery was significantly (P<0.05) higher than that of the control group. The ascorbic acid levels in the cord
blood of the newly born babies were significantly (P<0.01) higher than the maternal level. There was insignificant difference
in the haematological parameters between the pregnant and non-pregnant women. 相似文献
6.
Santoshi R. Ghodake A. N. Suryakar R. D. Ankush K. Shaikh A. V. Katta 《Indian journal of clinical biochemistry : IJCB》2010,25(1):82-85
Nephrotic syndrome is the common chronic disorder characterized by alteration of permeability of the glomerular capillary
wall, resulting in its inability to restrict the urinary loss of proteins. Nephrotic syndrome is characterized by heavy proteinuria,
hypoalbuminemia, hyperlipidemia associated with peripheral edema. The molecular basis of glomerular permselectivity remains
largely unknown. In recent years it has been proposed that Nephrotic syndrome is a consequence of an imbalance between oxidant
and antioxidant activity. The present study was aimed to test that the reactive oxygen species are the mediators of excessive
protein permeability and other complications of Nephrotic syndrome. For this 30 adults with Nephrotic syndrome were studied.
The control group comprised 30 healthy adults matched for age. Serum levels of lipid peroxides, nitric oxide (NO⊙), α- tocopherol,
ascorbic acid, erythrocyte superoxide dismutase activity, serum albumin, uric acid, cholesterol and plasma total antioxidant
capacity were measured. Student’s ‘t’ test was applied for statistical analysis. There was a significant increase in lipid
peroxide (1.58 ± 0.42 in controls, 3.64 ±1.3 in patients) (P<0.001) levels in study group as compared with controls. α-tocopherol
(12.95 ± 1.04 in controls, 9.93 ± 1.43 in patients) (P<0.001), erythrocyte SOD activity(1.88 ± 0.9 in controls 1.07 ± 0.5
in patients) (P=0.01), serum albumin(4.06 ± 0.50 in controls, 3.04 ± 0.11 in patients) (P<0.001), and plasma total antioxidant
capacity (847.33 ± 126.83 in controls, 684.00±102.94 in patients) (P<0.001) were significantly decreased. There was non-significant
increase in uric acid (P>0.05), a non-significant decrease in NO⊙ (38.48 ± 15.47 in controls 37.47 ± 14.27 in patients) (P>0.05)
and ascorbic acid levels ascorbic acid,( 0.95 ± 0.31in controls 0.79 ± 0.30 in patients) (P>0.05) in study group as compared
with controls. Imbalance between oxidants and antioxidants may contribute to pathogenesis of proteinuria and related complications
in nephrotic syndrome. 相似文献
7.
In order to determine whether the screening of lipid profile is justified in patients with hypothyroidism we estimated serum
lipids in cases having different levels of serum TSH. 60 patients of hypothyroidism in the age group of 20 to 60 yrs were
studied for thyroid profile over a period of one year. On the basis of serum TSH level the cases were divided into three groups:
In the first group TSH concentration was 8.8±2.99 μlU/ml, 95% confidence interval (Cl) 8.8±1.07, whereas serum total cholesterol
and LDL-chol levels were 196±37.22 and 126±29.17 mg/dl respectively. The statistical analysis of these two groups showed a
significant correlation between raised TSH levels and serum total cholesterol and LDL-chol (P<0.05 & P<0.01) respectively.
We conclude that hypothyrodism is associated with changes in lipid profile. 相似文献
8.
Sarita Chavan Laxmayya Sava Vishal Saxena Sandhya Pillai Alka Sontakke Digamber Ingole 《Indian journal of clinical biochemistry : IJCB》2005,20(1):150-152
Glutathione, the dominant intracellular thiol, plays an important protective role against oxidative stress. The accidental
findings of increased reduced glutathione level postprandially as compared to post absorptive level prompted the design of
present study. Reduced Glutathione levels were estimated in 50 healthy individuals in post absorptive and postprandial phase
by taking whole blood in ACD bulb. Mean postprandial reduced Glutathione (9.60±3.39 μmole/gm of Hb) is significantly increased
than mean postabsorptive level (5.53±0.88 μmole/gm of Hb; p<0.001). It also shows positive correlation (r=0.65) between these
two GSH levels. So present study suggests that post absorptive specimen collection is preferable over random or postprandial
as the former reflects the true basal level of reduced glutathione. 相似文献
9.
D. Rajasekhar K. S. S. Saibaba P. V. L. N. Srinivasa Rao S. A. A. Latheef G. Subramanyam 《Indian journal of clinical biochemistry : IJCB》2004,19(2):53-59
In an attempt to search for risk factors which can explain the increasing prevalence of coronary heart disease (CHD) in Indian
population, we conducted a case-control study to assess the association of Lipoprotein (a)(Lp(a)) with CHD. One hundred and
fifty one consecutive patients with clinical and angiographic evidence of CHD and forty-nine healthy controls were drawn for
the study. Triglycerides, very low density cholesterol (VLDL-C), total cholesterol (total-C)/high density cholesterol (HDL-C)
ratio, low density cholesterol (LDL-C)/HDL cholesterol ratio and Lp(a) were found to be higher in patients than controls.
In female sex and in those with family history of CHD, higher total and LDL cholesterol levels were observed to be associated
with higher Lp(a) levels. Lp(a) levels were also found to be higher in triple vessel disease than other vessel disease patients.
Significant difference in Lp(a) levels were observed between normal coronaries vs. single and triple vessel disease(P<0.05)
and also between single vs. double and triple vessel disease (P<0.01).Lp(a) levels correlated positively with vessel severity(P<0.005).
Lp(a) levels >25 mg/dl were associated with coronary heart disease (Odds ratio 1.98 P<0.05 95% CI 0.007–1.18). Our findings
suggest a cut-off level of 25mg/dl for determination of risk of CHD. Studies from different areas involving larger sample
size are needed to confirm the findings of the present study. 相似文献
10.
Praveen Kumar Shetty T. N. Pattabiraman 《Indian journal of clinical biochemistry : IJCB》1998,13(1):46-51
Elastase activity was found to be significantly increased in periodontitis (0.872±0.4270 absorbance units/mg protein, mean±S.
D., 1.05±0.61 units/ml saliva), gingivitis (0.772±0.416 units/mg protein, 1.515±0.952 units/ml) and diabetes (0.549±0.286
units/mg protein, 1.20±0.769 units/ml) compared to normals (0.255±0.089) units/mg protein, 0.264±0.079 units/ml). Chymotryptic
activity was not found to be increased in these disease conditions over the normal level (0.284±0.096 units/mg protein). Aminopeptidase
activity was elevated only in periodontitis (0.670+0.140 units/mg protein) compared to normals (0.349±0.100 units/mg protein).
Trypsin-like activity was also found to be significantly raised in periodontitis compared to normals when Pro-Phe-Arg-p-nitroanilide
(0.666±0.204 units/mg protein), Ile-Pro-Arg-p-nitroanilide (1.59±0.260 units/mg protein) and Pyroglu-Pro-Arg-p-nitroanilide
(1.82±0.380 units/mg protein) were used as substrates. The normal values with these three substrates were respectively, 0.454±0.110,
1.04±0.231 and 1.15±0.312 units/mg protein. Total protein level in saliva was found to be significantly elevated in gingivitis
(209±66.8 mg/dl) and diabetes (204±68.0) compared to normal values (107±20.7). Increase in periodontitis was marginal (127±28.3
mg/dl). Expression of proteolytic activities normalized to protein level was useful in differential diagnosis. Increase in
elastase level in saliva is not a specific marker for periodontal diseases. 相似文献
11.
T. Angeline RitaMary Aruna K. Ramadevi G. Mohan Nirmala Jeyaraj 《Indian journal of clinical biochemistry : IJCB》2003,18(1):103-106
Coronary artery disease is now a major health problem in India. In past few decades the battle to reduce the incidence of
coronary artery disease has led the researchers to look for various clinical markers, which would help early diagnosis of
the diseases. The present study was undertaken to assess the level of lipoprotein (a) [Lp(a)] and few other lipids in selected
myocardial infarction (MI) patients below 45 years without having any traditional risk factors but with positive family history.
Fasting blood samples were taken from 65 patients and their total cholesterol, LDL cholesterol, VLDL cholesterol, HDL cholesterol,
triglycerides and serum Lp(a) were determined. The control group consisted of 50 age matched healthy individuals. The mean
Lp(a) level was 58.6±3.20 mg/dl in patients and 19.70±0.18 mg/dl in controls. Thus Lp(a) levels were found significantly higher
in patients with MI (p<0.05 for patients versus control) as compared to the controls. There was no significant difference
in the levels of total cholesterol (TC), LDL, VLDL HDL, TGL as compared to controls but there was an increase in TC/HDL cholesterol
ratio. The results of this study suggest that high level of Lp(a) and TC/HDL ratio has a distinctive association with MI,
independent of other common coronary risk factors. Hence, Lp(a) level in serum emerges to be a promising marker for diagnosis
of coronary artery diseases. 相似文献
12.
Mohamed Ahmed Abdelmoaty Ahmed Mohamed Bogdady Mervat Mohamed Attia Nayel Abdelhamed Zaky 《Indian journal of clinical biochemistry : IJCB》2009,24(4):398-403
Hemodynamic disorders of liver cirrhosis complicated with portal hypertension are associated with an increased angiogenesis in animal model of portal hypertension and cirrhosis which were linked to increased expression of vascular endothelial growth factor (VEGF) and nitric oxide (NO). The aim of study was to evaluate the serum concentration of VEGF and total nitric oxide (NO) in liver cirrhosis and the possible association with the degree of liver insufficiency. VEGF and NO were measured in serum of 64 patients with liver cirrhosis by ELISA and spectrophotometry respectively. The significant increase of serum VEGF was observed in liver cirrhosis compared to healthy individuals as well as serum NO (106.1 ± 66.7 vs. 41.5 ± 6 pg/mL, P < 0.05; 113.5 ± 65.8 vs. 20.8 ± 3.8 μmol/l, P< 0.001, respectively). Serum VEGF and NO showed significant associations with biochemical indices of liver function and with Child-pugh score where they were increased respectively to the degree of liver insufficiency. A significant association of raised serum NO in early stage of portal hypertension reflect its benefit in early expect of portal hypertension but, high serum VEGF in late stage may reflect its prognostic value in liver cirrhosis. 相似文献
13.
Serum total cholesterol and triglyceride levels were estimated in 45 dilated cardiomyopathy (DCM) patients and were compared
with 31 healthy controls. The total serum cholesterol (215±50 mg/dl) and serum triglyceride (162±76 mg/dl) levels in DCM patients
did not show any significant changes as compared to normal controls. The cholesterol and triglyceride and the individual lipoprotein
fractions, viz HDL, VLDL, LDL and chylomicrons were analysed in 10 patients. The values did not differ significantly when
compared to those of controls. These findings suggest that serum lipids may not play a role in the antietiopathogenesis of
DCM. 相似文献
14.
Some biochemical parameters in 12 young Muslim students who underwent fasting during the entire one month period of Ramadan were investigated. There was a significant reduction in their body weight (72.5±4.0 to 69.4±3.0 kg) and blood glucose levels (99.6±3.5 to 82.9±7.3 mg/dl). Though the morning plasma cortisol fell (215.2±22.1 to 105±11.2 μg/l) and the evening plasma cortisol rose (58.4±5.1 to 64.4±4.8 μg/l) significantly there was no reversal of the circadian rhythm of cortisol secretion. A decline in the diastolic blood pressure (80 to 75±6 of Hg) of these individuals though not significant was also noted. However, cholesterol (160.9±12.8 to 178.2±40.6 mg/dl) and HDL-Cholesterol (42.6±2.2 to 48.1±2.4 mg/dl) showed a tendency for increase. All the changed values were within the normal range. 相似文献
15.
Serge Herve Tiyong Ifoue C. Teugwa Mofor I. Gouado G. Teto T. Asonganyi P. H. Amvam Zollo 《Indian journal of clinical biochemistry : IJCB》2009,24(3):288-293
Oxidative stress is thought to be involved in the pathophysiology of malaria, especially in pregnancy where natural resistance
is markedly reduced. In the present study we investigated oxidative stress in 315 pregnant women out of which 159 had Plasmodium
falciparum malaria and 154 controls. We evaluated the level of lipid peroxidation products (MDA level) in the plasma, the
activity of erythrocyte antioxidant defense enzymes, superoxide dismutase (SOD, EC: 1.15.1.1) and catalase (Cat, EC: 1.11.1.6)
as well as the ability to resist oxidative stress by the FRAP (Ferric Reducing Ability of Plasma) assay. Total erythrocyte
protein levels were also examined. For the two groups of patients, several differences between the biochemical parameters
tested were found. Median parasitaemia in women with malaria was 25,392 parasites/μl of blood (Range1200–82000), while in
controls we had no parasites found in thin and thick smears. Levels of lipid peroxidation products (MDA) were significantly
higher in patients with parasitemia than in healthy asymptomatic volunteers (mean: 0.844 ± 0.290 and 0.384 ± 0.129 respectively,
p<0.001). This MDA level was higher in primigravidea and also correlates well with parasite density (p<0.001). Catalase activity
in erythrocytes of women with malaria did not differ statistically from that of controls. In contrast, SOD activity of patients
with malaria was found to be significantly higher than that of controls (mean: 0.7899 ± 0.2777 and 0.4263 ± 0.2629 respectively,
p<0.05). FRAP values declined, from parasitemic patients (1.4619 ± 0.6565) compare to controls (2.4396 ± 0.8883, p<0.05),
particularly in the first and third trimester of gestation (p<0.05 and p<0.01 respectively). Finally, total erythrocyte protein
concentrations of women with malaria did not differ from that of the controls. Our results suggest an imbalance between oxidants
and antioxidants in pregnant women suffering from malaria, a situation which could lead to severe damage for either the mother
or the fetus. Therefore, further research should be done to assess the potential benefits of antioxidant supplementation for
the pregnant women suffering from malaria. 相似文献
16.
K Sudha Ashalatha V Rao S. N. Rao Anjali Rao 《Indian journal of clinical biochemistry : IJCB》2002,17(1):34-41
Oxidative stress is implicated in the etiopathogenesis of a variety of human diseases. Therefore, in the present study, erythrocyte
lipid peroxidation, percentage hemolysis, antioxidant enzymes viz., glutathione reductase, glutathione peroxidase, superoxide
dismutase and plasma antioxidants viz., ceruloplasmin, vitamins A,E and C have been determined in 19 patients with tubercular
meningitis (TBM) and 50 normals. Six patients who were treated with antibiotics were considered for the follow up. The statistical
analysis was carried out by Mann Whitney U test and Wilcoxon rank sum test. Lipid peroxidation (P<0.02), percentage hemolysis
(P<0.001) and plasma ceruloplasmin (P<0.0001) of TBM patients were significantly higher, whereas erythrocyte glutathione reductase
(P<0.05) and plasma antioxidant vitamins A, E and C (P<0.01, P<0.05 respectively) were significantly lower than those of the
controls. In the follow up patients the glutathione reductase and catalase levels were significantly high (P<0.05) compared
to their pre-treated condition. Vitamin C and E levels have attained normal range. This study indicated that the blood antioxidant
status of TBM patients which was low compared to controls improved after treatment, suggesting the role of free radicals in
TBM. 相似文献
17.
J. O. Adebayo A. O. Akinyinka G. A. Odewole J. I. Okwusidi 《Indian journal of clinical biochemistry : IJCB》2007,22(1):29-32
The effect of caffeine intake on the risk of coronary heart disease was studied. Twenty-one rats used were randomly divided
into three experimental groups, the first group served as the control while the second and third groups were administered
caffeine orally at doses of 10mg/kg body weight and 20mg/kg body weight respectively for fourteen days. Caffeine, at 10mg/kg
body weight, significantly increased (P<0.05) serum LDL- cholesterol concentration and coronary heart disease risk ratio while
it significantly reduced (P<0.05) serum triacylglycerol concentration when compared with controls. At 20mg/kg body weight,
caffeine significantly increased (P<0.05) coronary heart disease risk ratio while it significantly reduced (P<0.05) serum
HDL-cholesterol concentration and serum triacylgycerol concentration when compared with controls. No dose response effect
was observed possibly suggestive of a threshold effect. These results suggest that caffeine predisposes consumers of caffeine
containing beverages to coronary heart disease. 相似文献
18.
P. K. Nigam V. S. Narain Naveen Chandra V. K. Puri R. K. Saran S. K. Dwivedi M. Hasan 《Indian journal of clinical biochemistry : IJCB》1995,10(2):106-109
Blood samples from 39 patients with acute myocardial infarction and 15 healthy controls were analysed for serum and platelet sialic acid. Serum sialic acid levels in patients with acute myocardial infarction were significantly higher than controls (mean 2.7±0.46 μmol/ml Vs. 1.91±0.17 μmol/ml respectively). Levels of serum orosomucoid, an acute phase reactant, containing sialic acid, were also higher in these patients, suggesting a possible non-specific mechanism of increase in serum sialic acid concentration. In contrast, platelets contained significantly less sialic acid in patients with acute myocardial infarction than control (26.73±1.57 nmol/mg protein and 31.97±2.68 nmol/mg protein respectively). 相似文献
19.
Ramesh Chandra Ritu Aneja Charu Rewal Rama Konduri Sujaka K. Dass Shefali Agarwal 《Indian journal of clinical biochemistry : IJCB》2000,15(2):155-160
In this communication, we show the modulatory potential of papaverine, an opium alkaloid and a well known vasodilator agent
on the ethanol-induced hepatic oxidative stress in male Wistar rats. Ethanol treatment (50% v/v) enhanced lipid peroxidation
significantly accompanied by a decline in the activities of glutathione peroxidase (G-Px), glutathione reductase (GR) and
depletion in levels of hepatic glutathione (GSH). Ethanol administration increased hepatic glutathione-s-transferases (GST).
Enhanced lipid peroxidation induced by ethanol was significantly reduced when papverine was coadministered (P<0.05). In addition,
the depleted levels of glutathione and inhibited activities of G-Px and GR recovered significantly (P<0.05) levelling off
to control values on co-exposure. Papaverine (200 mg/kg bw) effectively antagonised the ethanol-induced lipid peroxidation
and impaired glutathione levels and glutathione dependent enzyme systems. Our results suggest that papaverine is an effective
chemopreventive agent in the liver and may suppress the ethanol-induced hepatotoxicity. 相似文献
20.
Suneesh Kumar Pachathundikandi Earaly Thomas Varghese 《Indian journal of clinical biochemistry : IJCB》2006,21(2):114-117
Blood zinc protoporphyrin (ZPP), serum total protein (TP), and total cholesterol (TC) levels in automobile workshop workers
in relation to lead toxicity were analysed. In the present study, automobile workshop workers (healthy male workers at an
age between 28 and 35 from four major automobile workshops in Kottayam, Kerala State, India) and the control (male healthy
adults at an age between 28 and 35 residing at Aymanam, a distant village at Kottayam District, Kerala having reduced or no
chance of lead exposure) displayed significant difference in blood lead (BPb) and blood ZZP (BZPP) level. The mean value of
BPb in automobile workshop workers was 15.76±0.33 μg/dl, while in the control it was 8.20±0.15 μg/dl. In automobile workshop
workers, the mean value of BZPP was 34.2±0.62 μg/dl. The control group exhibited a mean of 11.5±0.22 μg/dl. Automobile workshop
workers exhibited significant increase in BZPP was corresponding to the increase in BPb level. The total protein levels estimated
in automobile workshop workers showed significant decrease compared to control individuals, but was within the reference range
of healthy individuals. The mean value of TP level in automobile workshop workers and control was 6.9±0.13 g/dl and 7.71±0.18
g/dl, respectively. There was no significant difference in blood haemoglobin (BHb) level among the automobile workshop workers
and control. The serum TC level in automobile workshop workers showed significant decrease compared to the control individuals,
but was with in the reference range of healthy individuals. The mean level of serum TC in automobile workshop workers was
162.00±3.44 mg/dl and the same in control was 172.86±4.32 mg/dl. The present study affirms occupational lead toxicity in automobile
workshop workers and its effect on serum protein and cholesterol levels. 相似文献