共查询到19条相似文献，搜索用时 234 毫秒
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随着人类基因组图谱的绘制完成,基因组研究由结构基因组学转入到功能基因组学。蛋白质是基因功能的直接执行者,蛋白质相互作用是细胞进行代谢活动的基础。主要综述研究蛋白质相互作用的重要意义、研究方法,以及植物蛋白质相互作用的研究进展。 相似文献
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木本植物有许多不同于一年生草本植物的生物学特性，生物学家提出将木本植物
作为研究多年生植物的模式体系。杨属Populus树种由于研究基础较好且基因组较小，目前已
被广泛地接受作为多年生植物基因组研究的模式物种。随着杨属树种全基因组序列的测定，
杨属树种在多年生植物的功能基因组研究及一些基础科学问题的研究中将发挥重要作用。本
文综述了杨属树种基因组研究的历史、进展及将来的研究热点，旨在为我国多年生植物基因
组研究提供参考和借鉴。本文主要论述了以下几个方面的内容:（1）对杨属树种开展的细胞
遗传学研究;（2）在分子水平上对杨属树种进行的基因组研究，内容包括遗传作图、基因组
测序、物理图谱构建、基因芯片及连锁不平衡分析;（3）杨属树种基因组信息在探讨一些基
础科学问题中的潜在应用。 相似文献
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功能基因组学研究 总被引：3，自引：0，他引：3
当前人类基因组研究的重心正在由“结构”向“功能”转移。一个以基因组功能研究为主要内容的所谓“后基因组时代”(post-genomics),即功能基因组学(functional genomics)时代即将到来。功能基因组学主要研究基因的识别及其功能信息的提取、鉴定和开发利用,涉及生物信息学、计算机生物学和生物医学研究等领域。其成果将深化对基因组遗传语言,基因结构与功能的关系,生命的起源与进化,细胞发育、生长、分化,以及疾病发生、发展的分子机理等问题的理解。功能基因组学的研究还将促进生命科学与数学、物理、化学、信息科学、计算机科学以及自动化技术等学科的交叉融汇,刺激相关学科技术领域的发展。 相似文献
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遗传改良是提升作物产量和品质的最重要推动力,但其潜力的发挥受到了常规育种技术的严重制约。近年来的研究表明,基于功能基因组学知识和技术的分子设计育种是克服常规育种技术瓶颈的有效途径。在我国水稻结构和功能基因组研究已获得重要成果的基础上,结合国际分子育种领域的最新进展,中科院拟系统开展水稻和小麦品种分子设计研究,建立和完善多基因组装分子设计育种的理论和技术体系,实现传统遗传改良向品种分子设计的跨越,培育出具有高产、优质、高效、抗病虫、耐逆和稳产性状的水稻和小麦新品种。 相似文献
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水稻是最重要的粮食作物之一,是世界约一半以上人口的主要口粮。水稻作为禾本科植物基因组研究的模式作物,具有十分重要的意义。中国科学院国家基因研究中心率先完成了国际水稻基因组计划的第4号染色体全长序列的精确测序,该成果已在英国的《自然》杂志发表。本文简要报告水稻基因组测序的意义和目前我国在这一领域已取得的进展,并着重介绍水稻基因组4号染色体精确测序和分析的成果。 相似文献
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BackgroundProfilin proteins (PRFs) are small (12–15 kD) actin-binding protein, which play a significant role in cytoskeleton dynamics and plant development via regulating actin polymerization. Profilins have been well documented in Arabidopsis, Zea mays L. as well as Phaseolus vulgaris, however no such fully characterization of rice (Oryza sativa L.) profilin gene family has been reported thus far.ResultIn the present study, a comprehensive genome-wide analysis of rice PRF genes was completed and three members were identified. OsPRF1 and OsPRF2 shared 98.5% similarity (6 nucleotide divergence), but the deduced amino acid sequences of OsPRF1 and OsPRF2 are fully identical. In contrast, the OsPRF3 presents relatively lower similarity with OsPRF1 and OsPRF2. Phylogenetic analysis also support that OsPRF1 has a closer relationship with OsPRF2. Expression pattern analysis revealed the differential expression of OsPRFs in tissues of mature plant, which suggested the potential spatial functional specificity for rice profilin genes. Subcellular localization analysis revealed the OsPRFs were localized in cytoplasm and nucleus and all of them could bind actin monomers. Furthermore, abiotic stresses and hormones treatments assay indicated that the three OsPRF genes could be differentially regulated, suggesting that OsPRF genes might participate in different stress processes in rice.ConclusionsTaken together, our study provides a comprehensive analysis of the OsPRF gene family and will provide a basis for further studies on their roles in rice development and in response to abiotic stresses.How to cite: Zhang Y, Dong G, Wu L, et al. Identification and characterization of profilin gene family in rice. Electron J Biotechnol 2021;54. https://doi.org/10.1016/j.ejbt.2021.08.004. 相似文献
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Xier Luo Yu Zhou Bing Zhang Yi Zhang Xiaobo Wang Tong Feng Zhipeng Li Kuiqing Cui Zhiqiang Wang Chan Luo Hui Li Yanfei Deng Fenghua Lu Jianlin Han Yongwang Miao Huaming Mao Xiaoyan Yi Cheng Ai Shigang Wu Alun Li Zhichao Wu Zijun Zhuo Do Da Giang Bikash Mitra Mohammad Farhad Vahidi Shahid Mansoor Sahar Ahmed Al-Bayatti Eka Meutia Sari Neena Amatya Gorkhali Sigit Prastowo Laiba Shafique Guoyou Ye Qian Qian Baoshan Chen Deshun Shi Jue Ruan Qingyou Liu 《国家科学评论(英文版)》2020,7(3):686
Domesticated buffaloes have been integral to rice-paddy agro-ecosystems for millennia, yet relatively little is known about the buffalo genomics. Here, we sequenced and assembled reference genomes for both swamp and river buffaloes and we re-sequenced 230 individuals (132 swamp buffaloes and 98 river buffaloes) sampled from across Asia and Europe. Beyond the many actionable insights that our study revealed about the domestication, basic physiology and breeding of buffalo, we made the striking discovery that the divergent domestication traits between swamp and river buffaloes can be explained with recent selections of genes on social behavior, digestion metabolism, strengths and milk production. 相似文献
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Generating gene summaries from biomedical literature: A study of semi-structured summarization 总被引：3，自引：0，他引：3
Xu Ling Jing Jiang Xin He Qiaozhu Mei Chengxiang Zhai Bruce Schatz 《Information processing & management》2007,43(6):1777
Most knowledge accumulated through scientific discoveries in genomics and related biomedical disciplines is buried in the vast amount of biomedical literature. Since understanding gene regulations is fundamental to biomedical research, summarizing all the existing knowledge about a gene based on literature is highly desirable to help biologists digest the literature. In this paper, we present a study of methods for automatically generating gene summaries from biomedical literature. Unlike most existing work on automatic text summarization, in which the generated summary is often a list of extracted sentences, we propose to generate a semi-structured summary which consists of sentences covering specific semantic aspects of a gene. Such a semi-structured summary is more appropriate for describing genes and poses special challenges for automatic text summarization. We propose a two-stage approach to generate such a summary for a given gene – first retrieving articles about a gene and then extracting sentences for each specified semantic aspect. We address the issue of gene name variation in the first stage and propose several different methods for sentence extraction in the second stage. We evaluate the proposed methods using a test set with 20 genes. Experiment results show that the proposed methods can generate useful semi-structured gene summaries automatically from biomedical literature, and our proposed methods outperform general purpose summarization methods. Among all the proposed methods for sentence extraction, a probabilistic language modeling approach that models gene context performs the best. 相似文献
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鸭稻共作对土壤微生物数量及其功能多样性的影响 总被引：11，自引：1，他引：10
鸭稻共作起源于我国传统的稻田养鸭,作为一种环境友好型的生态农业技术,许多研究表明该模式具有良好的生态效应。为了进一步探讨鸭稻共作对稻田土壤微生物群落的影响,于2005年在华南农业大学增城教学科研基地进行了田间试验,共设计鸭稻区、浑水区、清水区和常规区4个处理,采用平板培养法和BIOLOG技术研究了其对稻田土壤微生物群落动态及功能多样性的影响效应。结果表明,鸭稻共作能够增加水稻生长中后期稻田土壤可培养的微生物总数以及细菌、放线菌和真菌数量;与常规区相比,土壤微生物总数、细菌、放线菌在抽穗期、成熟期的差异显著,真菌数量在乳熟期、成熟期的差异显著。BIOLOG分析显示,与清水区相比,稻田放鸭能够提高土壤微生物群落的碳源利用能力和整体代谢活性,显著增加水稻抽穗期的微生物功能多样性。说明鸭稻共作系统对稻田土壤微生物群落数量、代谢活性和功能多样性的提高均具有积极作用。 相似文献
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《中国科学院院刊(英文版)》2009,23(1):6-6
Understandlng the interactions between ecological systems andthe environment is a priority for the studies of global change, evolutionary biology, and functional genomics. Controlled environment facilities, like CO2 phytotrons, are necessary for acquiring such an understanding. 相似文献
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The concept of an “information space” provides a powerful metaphor for guiding the design of interactive retrieval systems. We present a case study of related article search, a browsing tool designed to help users navigate the information space defined by results of the PubMed® search engine. This feature leverages content-similarity links that tie MEDLINE® citations together in a vast document network. We examine the effectiveness of related article search from two perspectives: a topological analysis of networks generated from information needs represented in the TREC 2005 genomics track and a query log analysis of real PubMed users. Together, data suggest that related article search is a useful feature and that browsing related articles has become an integral part of how users interact with PubMed. 相似文献