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11.
D. Burcu Hazer Ercan Bal Gülay Nurlu Kemal Benli Serdar Balci Feral Öztürk Baki Hazer 《Journal of Zhejiang University. Science. B》2013,14(11):993-1003
Objective
This study aims to investigate the degree of biocompatibility and neuroregeneration of a polymer tube, poly-3-hydroxyoctanoate (PHO) in nerve gap repair.Methods
Forty Wistar Albino male rats were randomized into two groups: autologous nerve gap repair group and PHO tube repair group. In each group, a 10-mm right sciatic nerve defect was created and reconstructed accordingly. Neuroregeneration was studied by sciatic function index (SFI), electromyography, and immunohistochemical studies on Days 7, 21, 45 and 60 of implantation. Biocompatibility was analyzed by the capsule formation around the conduit. Biodegradation was analyzed by the molecular weight loss in vivo.Results
Electrophysiological and histomorphometric assessments demonstrated neuroregeneration in both groups over time. In the experimental group, a straight alignment of the Schwann cells parallel to the axons was detected. However, autologous nerve graft seems to have a superior neuroregeneration compared to PHO grafts. Minor biodegradation was observed in PHO conduit at the end of 60 d.Conclusions
Although neuroregeneration is detected in PHO grafts with minor degradation in 60 d, autologous nerve graft is found to be superior in axonal regeneration compared to PHO nerve tube grafts. PHO conduits were found to create minor inflammatory reaction in vivo, resulting in good soft tissue response. 相似文献12.
Shahzad Fakhar Xiu GuoYi Khan Imran Shahbaz Muhammad Riaz Muhammad Usman Abbas Adnan 《Asia Pacific Education Review》2020,21(1):121-141
Asia Pacific Education Review - In the provision of massive open online courses (MOOCs), cloud computing services enable students to synchronize their study materials anywhere, anytime, and using... 相似文献
13.
Rozilah Katan Siti Ezaleila Mustafa Hamedi M. Adnan 《Publishing Research Quarterly》2018,34(3):362-377
Advancements in digital technology are making waves in the publishing industry and e-publishing is starting to make its mark in the market. Although publishers view e-publishing as an opportunity to exploit products and new distribution channels, some of them are seeing this development as a risk rather than an opportunity, and thus are not willing to participate in these changes. This study was conducted to determine the readiness of e-publishing among Malaysian book publishers based on the E-Publishing Readiness Assessment Model. The results found that publishers in Malaysia are prepared in terms of infrastructure and human resources. However, only a small percentage of them are willing to practice e-publishing by publishing at least one e-book, while the majority is taking a wait and see approach before they start issuing e-books. Interviews with two companies displaying high levels of e-readiness and low e-readiness, showed a willingness depend on the decision of the company’s top management. In addition, external factors such as market demand, technological pressure, competition, consumer habits and police and government policies also affect the results of the top management to run e-publishing in their respective companies. Through these findings, the government and agencies involved in the publishing industry may be able to help find a solution when designing a strategy for improving e-publishing practices in Malaysia. 相似文献
14.
A renaissance in engineering PhD education 总被引：1，自引：1，他引：0
Adnan Akay 《European Journal of Engineering Education》2008,33(4):403-413
This paper addresses the role of engineering PhD education and its relationship to innovation and technology, and the need to reconsider how we educate PhD engineers. Much of the effort on engineering education in the last two decades focused on undergraduate education with a few exceptions that relate to masterdegree programs. Doctoral education in engineering prepares the next generation faculty, researchers, and technology leaders and warrants our attention. Whilst current education has been largely responsible for technological advances, there is a need for a new model of engineering PhD education that prepares renaissance engineers. This paper focuses on the doctoral education and its role in the USA; however, the issues addressed are universal among the countries that offer PhD degrees in engineering. 相似文献
15.
Hamedi M. Adnan 《Publishing Research Quarterly》2011,27(3):268-276
Photocopying of reading materials, especially from holdings in libraries is common practice among Malaysian university students.
It is unusual to find a student not making photocopies from books or journals. Photocopying machines are easily found in the
campus, especially in the libraries with full cooperation from the machine operators. This article will discuss the copyright
law in Malaysia with regard to photocopying practices, especially on the controversial term of “fair use” or “fair dealing”
as stated in the act. The second part relates to the main findings from a survey conducted in 2009 about photocopying among
university students, and the last part provide alternatives available to publishers on ways to control and to overcome this
problem. 相似文献
16.
Anatomy is shifting toward a greater focus on adopting digital delivery. To advance digital and authentic learning in anatomy, a flipped classroom model integrating multimodal digital resources and a multimedia group assignment was designed and implemented for first-year neuroanatomy and third-year regional anatomy curricula. A five-point Likert scale learning and teaching survey was conducted for a total of 145 undergraduate health science students to evaluate students' perception of the flipped classroom model and digital resources. This study revealed that over two-thirds of participants strongly agreed or agreed that the flipped classroom model helped their independent learning and understanding of difficult anatomy concepts. The response showed students consistently enjoyed their experience of using multimodal digital anatomy resources. Both first-year (75%) and third-year (88%) students strongly agreed or agreed that digital tools are very valuable and interactive for studying anatomy. Most students strongly agreed or agreed that digital anatomy tools increased their learning experience (~80%) and confidence (> 70%). The third-year students rated the value of digital anatomy tools significantly higher than the first-year students (p = 0.0038). A taxonomy-based assessment strategy revealed that the third-year students, but not the first-year, demonstrated improved performance in assessments relating to clinical application (p = 0.045). In summary, a flipped anatomy classroom integrating multimodal digital approaches exerted positive impact upon learning experience of both junior and senior students, the latter of whom demonstrated improved learning performance. This study extends the pedagogy innovation of flipped classroom teaching, which will advance future anatomy curriculum development, pertinent to post-pandemic education. 相似文献
17.
本研究的目的在于构建一个电子环境中的可信任文件管理框架.通过文献研究和最佳实践,对可信任电子文件管理的有关标准进行整理,并将这些标准进行专家测试,建立了构建电子文件可信任管理所需的因素,即监管、文件保管系统、档案、技术、人员技能和素质.这个框架为良好的文件管理实践奠定了基础. 相似文献
18.
A vehicle system driven by two independent DC motors is presented here, one of which is used for the right wheel and the other is used for the left wheel. An adaptive compensator using Takagi-Sugeno fuzzy systems is proposed to control the vehicle system. The compensator includes an adaptive model identifier and adaptive controller. An online method is used to adjust the parameters of the identifier model to match the behavior model of the vehicle system. Then, the parameters of the identifier model are employed in a standard parallel-distributed compensator to provide asymptotically stable equilibrium for the closed-loop vehicle drive system, in which the velocity and direction angle of the vehicle are controlled. Results demonstrate that the proposed controller structure is robust to load changes and follows different trajectories very well. 相似文献
19.
Melinda G. Simon Ying Li Janahan Arulmoli Lisa P. McDonnell Adnan Akil Jamison L. Nourse Abraham P. Lee Lisa A. Flanagan 《Biomicrofluidics》2014,8(6)
Dielectrophoresis (DEP) has proven an invaluable tool for the enrichment of populations of stem and progenitor cells owing to its ability to sort cells in a label-free manner and its biological safety. However, DEP separation devices have suffered from a low throughput preventing researchers from undertaking studies requiring large numbers of cells, such as needed for cell transplantation. We developed a microfluidic device designed for the enrichment of stem and progenitor cell populations that sorts cells at a rate of 150,000 cells/h, corresponding to an improvement in the throughput achieved with our previous device designs by over an order of magnitude. This advancement, coupled with data showing the DEP-sorted cells retain their enrichment and differentiation capacity when expanded in culture for periods of up to 2 weeks, provides sufficient throughput and cell numbers to enable a wider variety of experiments with enriched stem and progenitor cell populations. Furthermore, the sorting devices presented here provide ease of setup and operation, a simple fabrication process, and a low associated cost to use that makes them more amenable for use in common biological research laboratories. To our knowledge, this work represents the first to enrich stem cells and expand them in culture to generate transplantation-scale numbers of differentiation-competent cells using DEP. 相似文献
20.
Adnan Akay 《European Journal of Engineering Education》2003,28(2):145-150
Technology that fuels the economy and adds to the quality of life can also bring with it unexpected complexities. The events of 11 September bring into sharp relief some of the vulnerabilities that exist in the world, and also challenge us to re-examine the role of engineers in society. To date, the traditional responsibilities of the engineering communities in preventing future catastrophes have been defined purely in terms of technological advances. However, it is clear that engineering must go beyond pure technology to consider also the causes of vulnerabilities and examine if and how engineering can address matters that are often embedded in the social and economic fabric of society. Moreover, engineers must go beyond being technical experts who understand and consider social, financial and political factors in their work, and become leaders in all arenas of society. These expectations call for renaissance engineers and the need for a renaissance in engineering education. Recommendations to cultivate a new generation of renaissance engineers centre on recognition of individual talent and customizing education accordingly. 相似文献