“21世纪杯”全国中学生口语竞赛作品选     

Charlie 《英语辅导》2004,(9):45-47

“21世纪杯”第二届全国中学生英语口语竞赛于2003年12月在苏州成功举办。来自全国各地的各路英语高手参加了本次比赛。他们用流利的英语现场演讲和敏捷的答辩尽显了风采，也让在场的中外评委对  相似文献   

Let＇s　Share!     

Charlie 《英语辅导》2005,(1):59-59

读者吴晓梦：我想问一下，为什么学了很多新单词，但是写作文时仍习惯用一些旧的单词，新单词总是用不上。可以教一教我怎样在作文中用上新单词吗?  相似文献   

Current status and future prospects of mesenchymal stem cell therapy for liver fibrosis     

Yang Guo  Bo Chen  Li-jun Chen  Chun-feng Zhang  Charlie Xiang 《Journal of Zhejiang University. Science. B》2016,17(11):831-841

Liver fibrosis is the end-stage of many chronic liver diseases and is a significant health threat. The only effective therapy is liver transplantation, which still has many problems, including the lack of donor sources, immunological rejection, and high surgery costs, among others. However, the use of cell therapy is becoming more prevalent, and mesenchymal stem cells (MSCs) seem to be a promising cell type for the treatment of liver fibrosis. MSCs have multiple differentiation abilities, allowing them to migrate directly into injured tissue and differentiate into hepatocyte-like cells. Additionally, MSCs can release various growth factors and cytokines to increase hepatocyte regeneration, regress liver fibrosis, and regulate inflammation and immune responses. In this review, we summarize the current uses of MSC therapies for liver fibrosis and suggest potential future applications.  相似文献   

Online Assessment of Applied Anatomy Knowledge: The Effect of Images on Medical Students' Performance     

Mandeep Gill Sagoo  Marc A.T.M. Vorstenbosch  Peter J. Bazira  Harold Ellis  Maria Kambouri  Charlie Owen 《Anatomical sciences education》2021,14(3):342-351

Anatomical examinations have been designed to assess topographical and/or applied knowledge of anatomy with or without the inclusion of visual resources such as cadaveric specimens or images, radiological images, and/or clinical photographs. Multimedia learning theories have advanced the understanding of how words and images are processed during learning. However, the evidence of the impact of including anatomical and radiological images within written assessments is sparse. This study investigates the impact of including images within clinically oriented single-best-answer questions on students' scores in a tailored online tool. Second-year medical students (n = 174) from six schools in the United Kingdom participated voluntarily in the examination, and 55 students provided free-text comments which were thematically analyzed. All questions were categorized as to whether their stimulus format was purely textual or included an associated image. The type (anatomical and radiological image) and deep structure of images (question referring to a bone or soft tissue on the image) were taken into consideration. Students scored significantly better on questions with images compared to questions without images (P < 0.001), and on questions referring to bones than to soft tissue (P < 0.001), but no difference was found in their performance on anatomical and radiological image questions. The coding highlighted areas of “test applicability” and “challenges faced by the students.” In conclusion, images are critical in medical practice for investigating a patient's anatomy, and this study sets out a way to understand the effects of images on students' performance and their views in commonly employed written assessments.  相似文献   

Plasticity of human menstrual blood stem cells derived from the endometrium     

Lin J  Xiang D  Zhang JL  Allickson J  Xiang C 《Journal of Zhejiang University. Science. B》2011,12(5):372-380

Stem cells can be obtained from women’s menstrual blood derived from the endometrium. The cells display stem cell markers such as Oct-4, SSEA-4, Nanog, and c-kit (CD117), and have the potent ability to differentiate into various cell types, including the heart, nerve, bone, cartilage, and fat. There has been no evidence of teratoma, ectopic formation, or any immune response after transplantation into an animal model. These cells quickly regenerate after menstruation and secrete many growth factors to display recurrent angiogenesis. The plasticity and safety of the acquired cells have been demonstrated in many studies. Menstrual blood-derived stem cells (MenSCs) provide an alternative source of adult stem cells for research and application in regenerative medicine. Here we summarize the multipotent properties and the plasticities of MenSCs and other endometrial stem cells from recent studies conducted both in vitro and in vivo.  相似文献   

Reflecting on the EFA Global Monitoring Report's framework for understanding quality education: A teacher's perspective in Eritrea     

Charlie Gordon 《International Journal of Educational Development》2010

This paper considers issues concerning the quality of education in Eritrea using the Education for All (EFA) Global Monitoring Report's (GMR) framework for quality education. Drawing on 2 years school-based professional experience in the country, the multiple factors affecting quality in schooling are discussed. The applicability of the GMR framework is then assessed. Given the recent militarisation of the Eritrean school system, it finds the framework seriously lacking, by failing to enable a critique of some of the issues that arguably go to the heart of the quality of education in the country.  相似文献   

和自己结婚的男人     

Charlie Fish 《中学文科》2009,(3):52-53

婚礼 “为何不呢？” 我的好朋友扎塔加牧师的这4个字改变了我的一生。他说,圣经上告诫男人不可以同他的姐妹、姑姨、母亲、岳母、女儿或是孙女结婚（即使受到诱惑）,可圣经上任何一个地方都没有规定说不可以同自己结婚啊。于是,当我告诉扎塔加牧师这正是我的想法时．他最终勉强说出了那4个决定性的字眼：“为何不呢？”  相似文献   

Interregional inventor networks as studied by patent coinventorships   总被引：3，自引：0，他引：3  

Olof Ejermo  Charlie Karlsson 《Research Policy》2006,35(3):412-430

We study the structure of the interregional inventor networks in Sweden by examining the residence of inventors and coinventors involved in Swedish patent applications to the European Patent Office. Several factors are found to influence the spatial affinity of regions. We find that spatial affinity extends beyond the region if it has less own R&D-related resources (business R&D, university R&D and patenting); if it is close to the other region and if it is relatively small. The resources of that other region plays a positive role if, in analogue fashion, that region has more R&D-related resources.  相似文献   

The microfluidics of the eccrine sweat gland,including biomarker partitioning,transport, and biosensing implications     

Z. Sonner  E. Wilder  J. Heikenfeld  G. Kasting  F. Beyette  D. Swaile  F. Sherman  J. Joyce  J. Hagen  N. Kelley-Loughnane  R. Naik 《Biomicrofluidics》2015,9(3)

Non-invasive and accurate access of biomarkers remains a holy grail of the biomedical community. Human eccrine sweat is a surprisingly biomarker-rich fluid which is gaining increasing attention. This is especially true in applications of continuous bio-monitoring where other biofluids prove more challenging, if not impossible. However, much confusion on the topic exists as the microfluidics of the eccrine sweat gland has never been comprehensively presented and models of biomarker partitioning into sweat are either underdeveloped and/or highly scattered across literature. Reported here are microfluidic models for eccrine sweat generation and flow which are coupled with review of blood-to-sweat biomarker partition pathways, therefore providing insights such as how biomarker concentration changes with sweat flow rate. Additionally, it is shown that both flow rate and biomarker diffusion determine the effective sampling rate of biomarkers at the skin surface (chronological resolution). The discussion covers a broad class of biomarkers including ions (Na⁺, Cl⁻, K⁺, NH₄⁺), small molecules (ethanol, cortisol, urea, and lactate), and even peptides or small proteins (neuropeptides and cytokines). The models are not meant to be exhaustive for all biomarkers, yet collectively serve as a foundational guide for further development of sweat-based diagnostics and for those beginning exploration of new biomarker opportunities in sweat.  相似文献