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Usha Goswami 《British Journal of Special Education》2004,31(4):175-183
The discipline of neuroscience draws from the fields of neurology, psychology, physiology and biology, but is best understood in the wider world as 'brain science'. Of particular interest for education is the development of techniques for 'imaging' the brain as it performs different cognitive functions. Cognitive neuroimaging has already led to advances in understanding some of the basic functions involved in learning and raised implications for education and special education in particular. For example, neuroimaging has enabled scientists to study the very complex processes underpinning speech and language, thinking and reasoning, reading and mathematics. In this article, Professor Usha Goswami of the University of Cambridge Faculty of Education first reviews basic information on brain development. She provides a brief introduction to the tools used in neuroimaging then considers recent findings from neuroscience that seem relevant to educational questions. Professor Goswami uses this review to suggest particular ways in which neuroscience research could inform special education. In its closing sections, this article provides authoritative perspectives on some of the 'neuromyths' that seem to have taken root in the popular imagination and argues for increased dialogue, in the future, between the disciplines of neuroscience and education. 相似文献
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Devika Tayal Binita Goswami S. K. Patra Reva Tripathi Alka Khaneja 《Indian journal of clinical biochemistry : IJCB》2014,29(2):139-144
Preeclampsia is a multisystem disorder associated with maternal hypertension, placental abnormalities and adverse fetal outcomes. The various pathways involved in its etiology include endothelial dysfunction, inflammatory milieu, lipid peroxidation and immunological imbalance. The present study was conducted to evaluate the causative and predictive role of nitric oxide, lipid peroxidation end products (MDA) and inflammatory cytokines (IL-6, TNF-α) in clinical presentation, severity and fetal outcome in preeclampsia. The study population was divided into 3 groups- Non- pregnant females comprising the control population; G1 and G2 groups included normal pregnant and pregnant females with preeclampsia with 50 patients in each group. Nitric Oxide and MDA levels were found to be highest in the preeclamptic patients as compared to other two groups. ROC curve analysis shows the superiority of the inflammatory markers as determinants of severity of preeclampsia which suggests the emerging role of pro inflammatory markers in the various pathological changes in preeclampsia. TNF-α emerged as the best marker in multivariate analysis and thus, has the potential for being used as a marker for PIH. Our study illustrates the multifactorial etiology of preeclampsia involving oxidative stress, proinflammatory milieu and endothelial dysfunction. 相似文献
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Lead poisoning presents a common acquired as well as congenital environmental threat to children’s health today. An unusual case of severe lead poisoning in breast fed male infant is presented here. The objective of the study is to describe a patient who developed clinical lead intoxication with an uncommon source of poisoning. A 6 months old male baby presented with gradual loss of weight, not feeding well and persistent vomiting. Laboratory investigation revealed that he was having anemia (Hb level 5.4 gm/dl), abnormal liver enzymes (including elevated transaminase activity) and high blood lead value (83 μg/dl). RBC morphology showed basophilic stippling with cabot ring, suggestive of a case of lead poisoning. A course of chelation treatment using calcium versenate (EDTACaNa2) was prescribed following which a radical solution for mobilization of lead from his systems was observed. 相似文献
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P.R. Goswami 《International Information and Library Review》2013,45(2-3):181-196
National statistical system is an integral part of knowledge base of government in all developing countries. In India, statistical agencies, which function under the aegis of government, produce a great variety of statistical information on different socio-economic variables. The purpose of this paper is to present an overview of socio-economic databases developed in India with special reference to initiatives taken by the data producing agencies for an user friendly dissemination programme. 相似文献
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Singh B Goswami B Gupta N Bajaj AD Mallika V 《Indian journal of clinical biochemistry : IJCB》2011,26(1):41-45
Preterm delivery is a major contributor for neonatal mortality. Intensive research is underway to establish a reliable biomarker
that can ascertain the risk of preterm delivery in pregnant women. The aim of our study was to evaluate the role of various
biochemical parameters as potential biomarker for risk assessment for preterm labor. Forty women presenting with preterm labor
and 40 women who delivered at term were included in the study. Parameters that were evaluated include corticotrophin (ACTH),
prolactin, thyroid stimulating hormone (TSH), ferritin and Alkaline Phosphatase (ALP). Serum ACTH, ferritin, ALP and Ferritin/Iron
ratio were significantly higher in the subjects who delivered prematurely as compared to the controls. Comparison of sensitivity,
specificity, likelihood ratio, positive and negative predictive values for different cut offs for ACTH, ferritin, ALP and
ferritin/iron ratio was carried out. Ferritin emerged as the best marker with area under curve of 0.96 as compared to 0.88
for ACTH, 0.825 for ALP and 0.735 for ferritin/iron ratio. Our study establishes the superiority of ferritin as a predictive
biomarker for preterm labor as compared to the rest of the parameters evaluated. 相似文献
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The modern sensation the field of Library and Information Science is the word e-library where information's are stored in a digital format. It actually enables the use of the new emerging technique XML for transporting information over internet and thus nullifies the disadvantages (viz. rigid transaction set, fixed business rule, high cost, and slow pace) of previously used EDI (Electronic Data Interchange) technique. Keeping in mind the necessity of rapid and dynamic information explosion the library in the modern era should be universal. This concept of spreading a centralized system in a geographically dispersed system is known as distributed system. In this work we represent a model that is distributed in nature and information is transferred by means of XML. 相似文献
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Neelakshi Sarma Sanasam Ranbir Singh Diganta Goswami 《Information processing & management》2019,56(1):151-166
With the explosion of multilingual content on Web, particularly in social media platforms, identification of languages present in the text is becoming an important task for various applications. While automatic language identification (ALI) in social media text is considered to be a non-trivial task due to the presence of slang words, misspellings, creative spellings and special elements such as hashtags, user mentions etc., ALI in multilingual environment becomes even more challenging task. In a highly multilingual society, code-mixing without affecting the underlying language sense has become a natural phenomenon. In such a dynamic environment, conversational text alone often fails to identify the underlying languages present in the text. This paper proposes various methods of exploiting social conversational features for enhancing ALI performance. Although social conversational features for ALI have been explored previously using methods like probabilistic language modeling, these models often fail to address issues related to code-mixing, phonetic typing, out-of-vocabulary etc. which are prevalent in a highly multilingual environment. This paper differs in the way the social conversational features are used to propose text refinement strategies that are suitable for ALI in highly multilingual environment. The contributions in this paper therefore includes the following. First, this paper analyzes the characteristics of various social conversational features by exploiting language usage patterns. Second, various methods of text refinement suitable for language identification are proposed. Third, the effects of the proposed refinement methods are investigated using various sentence level language identification frameworks. From various experimental observations over three conversational datasets collected from Facebook, Youtube and Twitter social media platforms, it is evident that our proposed method of ALI using social conversational features outperforms the baseline counterparts. 相似文献
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I. Mazumdar K. Goswami Md Suhrab Ali 《Indian journal of clinical biochemistry : IJCB》2017,32(1):110-116
Jewelry utilizes lead either directly or as a base metal. Costume jewelry requires lead before molding and plating the product with valuable metals. Therefore, such ornaments have a great potential to release heavy metals having health hazards. Also, jewelry makers engaged in preparing German silver, an alloy, apply lead in smelting, alloying, rolling and milling silver wires and pieces. The metal is taken up by blood, soft tissues and bone. The biological effects of lead are dependent upon the level and duration of exposure. Lead inhibits three enzymes of heme biosynthesis- δ-amino-levulinic-acid dehydratase (ALAD), coproporphyrin oxidase, and ferrochelatase, impairing heme synthesis and depressing serum level of erythropoietin resulting in decreased hemoglobin synthesis. Lead exposure also affects calcium metabolism and impair the synthesis of Calcitriol. In the present study, jewelry makers from Dhaka, Bangladesh, were shown to have significantly high levels of lead, protein, albumin, and parathormone in their blood, and significantly high amount of zinc-protoporphyrin and δ-amino-levulinic-acid in their urine. The control group, on the other hand showed significantly higher amounts of calcium (both total and ionized form) Vitamin D3 and non-activated erythrocyte ALAD in their blood, along with hemoglobin. It might be due to inhibition of 1-α-hydroxylase enzyme in renal tubules. Lead causes nephro-toxicity and inhibits 1-α- hydroxylase enzyme leading to decreased calcitriol synthesis resulting in impaired calcium absorption across gastro-intestinal tract and renal tubules. Low Vitamin D3 and significantly increased Parathyroid hormone (PTH) in study group has been found. 相似文献