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1.
Unstable angina is a critical condition of heart resulting from narrowing of vessels supplying blood to heart. Ischemia of the myocardium leads to oxidative stress and severe tissue damage. The objective of the present study was to determine the effect of l-arginine administration on the oxidant–antioxidant homeostasis which otherwise gets imbalanced in patients with cardiovascular diseases. The results obtained, show improvement in the oxidant–antioxidant levels of the subjects upon incorporation of l-arginine. Our findings suggest that supplementation of l-arginine along with regular anti-anginal therapy may be beneficial to the patients of unstable angina.  相似文献   
2.
Serum total cholesterol and triglyceride levels were estimated in 45 dilated cardiomyopathy (DCM) patients and were compared with 31 healthy controls. The total serum cholesterol (215±50 mg/dl) and serum triglyceride (162±76 mg/dl) levels in DCM patients did not show any significant changes as compared to normal controls. The cholesterol and triglyceride and the individual lipoprotein fractions, viz HDL, VLDL, LDL and chylomicrons were analysed in 10 patients. The values did not differ significantly when compared to those of controls. These findings suggest that serum lipids may not play a role in the antietiopathogenesis of DCM.  相似文献   
3.
This study provides an overview of the research output of Jawaharlal Nehru University, New Delhi, India, in terms of number of publications contributed by faculty members and researchers. The study analyzes bibliometric indicators of published research of Jawaharlal Nehru University as indexed in the Web of Science. There were 5,007 research publications from Jawaharlal Nehru University in the four decades from 1971–2010 (70s; 80s; 90s; and 2000s). The study noted encouraging trends in collaborative research work with multiple-authored research papers. International collaboration in research was also observed among the faculty members and researchers. English was the predominant language of communication. The social scientists and humanists of Jawaharlal Nehru University publish books which are not indexed in the Web of Science. Similarly, research work published in regional languages or published in national level journals are seldom included in the Web of Science. It suggests that research needs to be done by collecting data from the Indian Citation Index and books published by the researchers in order to get an accurate and consolidated picture of the research output of the university.  相似文献   
4.
Online open source software platforms, such as Sourceforge.net, play a vital role in creating an ecosystem that enables the creation and growth of open source projects. However, there is little research exploring the interactions between open source stakeholders and the platform. We believe that the sustainability of the platform crucially depends on financial incentives. While platforms can obtain these incentives through multiple means, in this paper we focus on one form of financial incentives—voluntary monetary donations by open source community members. We report findings from two empirical studies that examine factors that impact donations. Study 1 investigates the factors that cause some community members to donate and not others. We find that the decision to donate is impacted by relational commitment with open source software platform, donation to projects and accepting donations from others. Study 2 examines what drives the level of donation. We find that the length of association with the platform and relational commitment affects donation levels.  相似文献   
5.
Ovarian cancer has been emerged as a most common and lethal gynecological malignancy in India. High serum insulin and low adiponectin have been associated with increased risk of ovarian cancer. But their role in development of ovarian cancer is conflicting and little evidence is available. We aimed to evaluate blood levels of insulin and adiponectin in epithelial ovarian cancer (EOC) patients and their association with the risk to develop EOC. The study included following three groups; Group 1: fifty cases of cytohistopathologically confirmed cases of EOC, Group 2: fifty age matched cases of benign ovarian conditions and Group 3: fifty ages matched healthy controls with no evidence of any benign or malignant ovarian pathology as ruled out by clinical examination and relevant investigations. Cytohistopathologically confirmed and newly diagnosed cases of EOC and benign ovarian cancer were included in this study. The median value of fasting serum insulin was significantly high (15.0 µlU/ml, P = 0.02) and adiponectin were significantly low (5.1 µg/ml, P < 0.001) in ovarian cancer patients compared to benign ovarian tumors and healthy controls group. A significant increase risk of ovarian cancer was found in high tertile (≥ 18.7 µlU/ml) of serum insulin level (OR = 2.7; 95% CI = 1.00–6.67, P = 0.04) and lower tertile (≤ 5.45 µg/ml) of adiponectin level (OR = 3.2; 95% CI = 1.10–9.71, P = 0.03). High serum insulin level and low adiponectin levels were significantly associated with increased risk for development of ovarian cancer.  相似文献   
6.
Free radicals are implicated in various chronic diseases. There has always been a search for new antioxidants. In this paper we have investigated Tamra bhasma, a metallic ayurvedic preparation. It is a time-tested medicine in Ayurveda and is in clinical use for various ailments specifically the free radical mediated diseases. Our results show that Tamra bhasma inhibits lipid peroxidation (LPO), prevents the rate of aerial oxidation of reduced glutathione (GSH) content and induces the activity of superoxide dismutase (SOD) in rat liver homogenate in the bi-phasic manner. The drug was orally given for 7, 15 and 30 days in different doses. Best protective response was found at the dose of 0.5mg/100g body weight in albino rats, although it showed some histopathological changes at the dose of 20mg/100g body weight. The results suggest that this Ayurvedic preparation is not merely a source of copper metal, but it is a strong anti-oxidant with no detectable adverse effect in lower doses of therapeutic range.  相似文献   
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8.
Capitalizing on national anxieties, right wing populist leaders promise to enforce national borders with new constellations of policies that regulate and exclude Muslim bodies. Using the theoretical tool of “technologies of concern” (Jaffe-Walter, 2016), this essay critiques how state security discourses operate through public schools. Drawing on ethnographic research with Muslim youth in a Danish public school and an analysis of European integration policies, the author analyzes how policies and practices that ostensibly support young people’s integration enact everyday violence and coercive assimilation. Highlighting the perspectives of the young people she worked with, the author argues that state efforts to transform Muslim students into acceptable subjects of the nation-state encouraged their alienation and marginalization.  相似文献   
9.
The paper defines and explains e-governance. It also discusses an e-governance initiative Lokvani (which means voice of the masses) which has been taken in the small district of Sitapur; it is located in Uttar Pradesh, northern part of India. Highlights the upsides and downsides of Lokvani. This paper also dwells upon the challenges which must be overcome before implementing e-governance projects across the length and breadth of the country. It offers suggestions for successfully implementing e-governance in the country.  相似文献   
10.
In this experimental study, a portable biosensor was developed to detect β-human chorionic gonadotropin (β-hCG), which is extensively used in pregnancy tests and serves as a biomarker for ectopic pregnancy. The sensor used is an electric-double-layer field-effect transistor biosensor with the extended-gate design. Bias voltage is applied on the sensor to measure the resulting drain current signals. Gold electrode surface is functionally activated with an anti-β-hCG antibody to capture β-hCG protein. Fluorescence imaging technique is utilized to confirm the surface functionalization. The biosensor demonstrates a dynamically wide range of molecules as detection targets at very low sample concentrations, which shows the potential to detect ectopic pregnancy in very early stages and easily keep track of its periodic changes. It can be produced en masse and does not use additional labels/reagents or pre-processing techniques for the sample. This biosensor can significantly reduce the manufacturing costs and is comparable with the currently available commercial ß-hCG assays. It is suitable for early diagnosis of ectopic pregnancy with low cost and easy operation at home with urine samples.  相似文献   
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