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Introduction

The aim of this study was to identify clinical variables which may be independently associated with positivity of a cardiac troponin I (cTnI) assay in a large population of patients admitted to the emergency department (ED).

Materials and methods

3166 subjects, with at least two troponin I tests ordered within 6 hours in the ED, were studied. Patient data were statistically analyzed to identify clinical associations with increased values of Troponin I.

Results

Although patients with diagnosis of acute coronary syndrome displayed troponin I values significantly higher than those of other groups, positivity to troponin I (> 40 ng/L) was also observed in patients with other clinical conditions. In multivariate analysis, age, elevated heart rate and electrocardiographyc changes were independently associated with troponin I positivity at admission. In the whole study population troponin I positivity exhibited high sensitivity and negative predictive value, counterbalanced by low specificity and limited positive predictive value.

Conclusions

Troponin I positivity should be combined with history and clinical evaluation and cautiously interpreted in the ED, especially in patients exhibiting factors associated with higher troponin I levels such as older age, elevated heart rate or ECG changes.Key words: troponin I, acute coronary syndrome, emergency service, hospital, chest pain  相似文献   
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Due to the exponential growth of spatial information, effective management and curation of geospatial data has become a central concern for GIS libraries. Although geospatial data are often generated based on a set of well-established standards and protocols, best management practices in geospatial data services are still limited. In this paper, the authors review the common challenges of geospatial data management and curation, which include the application of big data, the emergence of Web GIS, and the advancement of cyberinfrastructures. A spatial education project is used as an example to discuss potential best management practices to address these challenges. It is demonstrated that librarians need to be involved at the early stage of a research project and work closely with researchers at all stages of the data life cycle for effective data management. With early involvement of a GIS librarian in the full project development process, all three challenges can be addressed by using best management practices in organizing, managing, publishing, distributing, and preserving the geospatial data.  相似文献   
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The original concept of a subculture of learning support in secondary schools developed from a study of ‘Support Teachers, Learning Difficulties’ in New South Wales, Australia. The study examined the influence of school culture on the service delivery model used by these support teachers in three case studies, one of which is reported in this article. Both research and policy recommend consultation and co‐teaching with a minimum of withdrawal of students with learning difficulties for intensive instruction. To employ the recommended service delivery model it was found that support teachers need to be immersed in a subculture of learning support within the school, which involves interacting with others who share similar values and beliefs about the education of students with learning difficulties. If such a subculture does not exist the support teacher must play a major role in its development. The use of the recommended service delivery model will enhance the education provided for students with learning difficulties.  相似文献   
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The purpose of the current study was to examine the viability of conducting a theory-based physical activity (PA) intervention on men with prostate cancer, and the impact of PA on quality of life (QOL). Participants were 31 men, average age of 67 years, with localized or metastatic prostate cancer undergoing androgen deprivation therapy (ADT). Global QOL, fatigue, and PA measures were conducted at baseline and following the 12-week intervention. An additional follow-up testing was conducted 4 months following the intervention (n = 18). Both moderate and strenuous bouts of exercise, as well as functional capacity, increased significantly from pre- to posttest. Both fatigue severity and resting heart rate decreased significantly at posttest. A trend toward improved global QOL was also noted. It was concluded that a 12-week home-based PA intervention may provide health and QOL benefits for prostate cancer patients undergoing ADT. Practitioners are encouraged to promote PA for prostate cancer survivors.  相似文献   
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Chronos is a traditionally marginalized term in rhetorical studies. Historically paired with kairos, chronos is commonly taken to refer to chronology, empty, homogenous, and external time. I argue for a reconsideration and redefinition of chronos that pairs the term with a critical materialist theory of time as change, immanent temporalities. Chronos understood as an entanglement of immanent temporalities informs chronistic criticism. Chronistic criticism is a conceptual criticism investigating the rhetorical arrangement, or synchronization, of multiple processes of change. Reconsidering chronos makes room for investigating time-related texts, like ‘Iraq's first national calendar. This calendar emerged after the establishment of the ‘Iraqi state under the League of Nation's Mandate System where British authorities were charged with building a modern nation state from territories of the former Ottoman Empire. I demonstrate chronistic criticism examining Gertrude Bell's digital archive for observations about successes, failures, and competitors with the national calendar. A vitalized chronos stands to make substantive contributions to the study of numerous rhetorical concepts. Specifically, for this investigation, chronos offers new insights into political myths, calendars, nation building, and the potential influences of nonhuman immanent temporalities.  相似文献   
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