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11.
Abstract

Carnosine was originally discovered in skeletal muscle, where it exists in larger amounts than in other tissues. The majority of research into the physiological roles of carnosine have been conducted on skeletal muscle. Given this and the potential for muscle carnosine content to be increased with supplementation, there is now a large body of research examining the ergogenic effects (or otherwise) of carnosine. More recent research, however, points towards a potential for carnosine to exert a wider range of physiological effects in other tissues, including the brain, heart, pancreas, kidney and cancer cells. Taken together, this is suggestive of a potential for carnosine to have therapeutic benefits in health and disease, although this is by no means without complication. Herein, we will provide a review of the current literature relating to the potential therapeutic effects of carnosine in health and disease.  相似文献   
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The article sets off with a brief summary of the history of appraisal and disposal of records as processed at the National Archives of Iceland (NAI) since its establishment in 1882 to present times. Rules on appraisal and disposal of records introduced in 1900, 1911, and 1916 were ignored and all records were kept. Status quo remained until 1985 when a new National Archives Act was passed. The appraisal and disposal process adopted then is described and explained. It included the publication of instructions on records management as well as forms relating to records management. The influence of acts of law on the appraisal and disposal process is explained. Finally the experience with the arrangement of organised appraisal in Iceland is described.  相似文献   
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The development of a Nurture Group can help a whole school to become 'a more inclusive, nurturing establishment', according to Rebecca Doyle. In this article she describes the evolution of a detailed Reintegration Readiness Scale, building on Nurture Group principles and practices. Two case studies illustrate the kinds of progress that can be made by individual pupils. This article goes on to note the benefits that nurturing approaches can bring to the whole school community and to indicate further developments for the future. Rebecca Doyle runs the Nurture Group at Canterbury Infant School in Thetford and used a DfEE-funded Best Practice Research Scholarship to develop the approaches she details in this practical and thought-provoking report.  相似文献   
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