The effect of network size on intra-network knowledge processes     

Donald?HislopEmail author 《知识管理研究与实践》2005,3(4):244-252

This paper addresses a neglected topic in the knowledge management literature: how the size of a network of actors affects the nature of intra-network social relations and knowledge processes. It makes a theoretical contribution to developing understanding in this area drawing on a range of literatures including practice-based perspectives on knowledge, the literature on the embeddedness of social relations, and relevant knowledge management literature. The central focus of this paper is on the relationship between network size, network density, and how these variables affect intra-network knowledge processes. It suggests that as network size increases network density is likely to decrease (as it becomes problematic for the actors in such networks to retain strong ties with a significant proportion of the network's members), which it will be suggested has significant ramifications for intra-network knowledge processes. This paper concludes by reflecting on the implications of the ideas developed for network-based forms of organizing, and innovation processes.  相似文献   

Association of Elevated Serum Lipoprotein(a), Inflammation,Oxidative Stress and Chronic Kidney Disease with Hypertension in Non-diabetes Hypertensive Patients     

Surapon?TangvarasittichaiEmail author  Patcharin?Pingmuanglaew  Orathai?Tangvarasittichai 《Indian journal of clinical biochemistry : IJCB》2016,31(4):446-451

Hypertension is the most common cardiovascular risk factor. Lipoprotein(a) [Lp(a)], inflammation, oxidative stress and chronic kidney disease (CKD) exacerbate the response to tissue injury and acts as markers of the vascular disease, especially in glomerulosclerosis. We compared the clinical characteristics of 138 non-diabetes hypertensive women (ndHT) patients with 417 non-diabetes normotensive subjects and tested the association of hypertension with Lp(a), inflammation, CKD and oxidative stress by using multiple logistic regression. BP, BMI, waist circumference, creatinine, Lp(a), inflammation and malondialdehyde levels were significantly higher and CKD state in the ndHT patients (p < 0.05). Multiple logistic regression showed hypertension associated with increased Lp(a), inflammation, ORs and 95 % CIs were 2.52 (1.33, 4.80), 2.75 (1.44, 5.27) after adjusting for their covariates. Elevated serum Lp(a) and inflammation levels concomitants with increased oxidative stress and CKD were the major risk factors associated with hypertension and implications for the increased risk of HT and vascular disease.  相似文献   

The effect of extremely high glucose concentrations on 21 routine chemistry and thyroid Abbott assays: interference study     

Serap ?uhadar  Mehmet K?seo?lu  Yasemin ?inpolat  Güler Bu?dayc?  Murat Usta  Tuna Semerci 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2016,26(1):53-60

Introduction

Extremely high glucose concentrations have been shown to interfere with creatinine assays especially with Jaffe method in peritoneal dialysate. Because diabetes is the fastest growing chronic disease in the world, laboratories study with varying glucose concentrations. We investigated whether different levels of glucose spiked in serum interfere with 21 routine chemistry and thyroid assays at glucose concentrations between 17-51 mmol/L.

Materials and methods

Baseline (group I) serum pool with glucose concentration of 5.55 (5.44-5.61) mmol/L was prepared from patient sera. Spiking with 20% dextrose solution, sample groups were obtained with glucose concentrations: 17.09, 34.52, and 50.95 mmol/L (group II, III, IV, respectively). Total of 21 biochemistry analytes and thyroid tests were studied on Abbott c8000 and i2000sr with commercial reagents. Bias from baseline value was checked statistically and clinically.

Results

Creatinine increased significantly by 8.74%, 31.66%, 55.31% at groups II, III, IV, respectively with P values of < 0.001. At the median glucose concentration of 50.95 mmol/L, calcium, albumin, chloride and FT4 biased significantly clinically (-0.85%, 1.63%, 0.65%, 7.4% with P values 0.138, 0.214, 0.004, < 0.001, respectively). Remaining assays were free of interference.

Conclusion

Among the numerous biochemical parameters studied, only a few parameters are affected by dramatically increased glucose concentration. The creatinine measurements obtained in human sera with the Jaffe alkaline method at high glucose concentrations should be interpreted with caution. Other tests that were affected with extremely high glucose concentrations were calcium, albumin, chloride and FT4, hence results should be taken into consideration in patients with poor diabetic control.Key words: assay interference, glucose interference, preanalytical phase, creatinine, Jaffe kinetic assay, thyroid function tests  相似文献   

Editorial zum Themenheft: ,,Datenbanksysteme‘‘     

Theo H?rder 《Informatik - Forschung und Entwicklung》2007,11(2):125-126

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Critical factors influencing secondary school pupil’s decisions to study computing in tertiary education: Gender differences     

Evrikleia?Tsagala  Maria?KordakiEmail author 《Education and Information Technologies》2007,12(4):281-295

This paper aims to determine the factors affecting the decisions of both male and female secondary school pupils whether or not to pursue undergraduate studies in Computing. It is based on research conducted in Greece, on a sample of 248 pupils, 135 of whom were female. All were aged 17 and about to decide on their future undergraduate studies. Questionnaires were used, addressing issues in the following four main categories: a) the reasons pupils chose/rejected Computing, b) how family and friends, the media and the school environment contribute to their decision, c) how pupils perceived their future after studying Computing and d) how pupils perceived the profile of a computer professional in terms of gender.

Maria KordakiEmail:

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Teachers' education, classroom quality, and young children's academic skills: results from seven studies of preschool programs   总被引：10，自引：0，他引：10  

Early DM  Maxwell KL  Burchinal M  Alva S  Bender RH  Bryant D  Cai K  Clifford RM  Ebanks C  Griffin JA  Henry GT  Howes C  Iriondo-Perez J  Jeon HJ  Mashburn AJ  Peisner-Feinberg E  Pianta RC  Vandergrift N  Zill N 《Child development》2007,78(2):558-580

In an effort to provide high-quality preschool education, policymakers are increasingly requiring public preschool teachers to have at least a Bachelor's degree, preferably in early childhood education. Seven major studies of early care and education were used to predict classroom quality and children's academic outcomes from the educational attainment and major of teachers of 4-year-olds. The findings indicate largely null or contradictory associations, indicating that policies focused solely on increasing teachers' education will not suffice for improving classroom quality or maximizing children's academic gains. Instead, raising the effectiveness of early childhood education likely will require a broad range of professional development activities and supports targeted toward teachers' interactions with children.  相似文献   

The HPT Model Applied to a Boutique‐Style Online Retail Store     

Rebecca Hayes  Caroline Godwin  Danielle Butts  Florence Martin 《Performance Improvement》2015,54(7):26-33

Suzy Q's is a retail business located in the southeastern United States. It offers hand‐knitted scarves; handmade hair accessories; handcrafted beaded jewelry such as necklaces, bracelets, and earrings; small handmade children's toys; and stock and custom‐printed T‐shirts. It began operations in early 2014. The owners established an online store and developed plans to sell items at local craft fairs and farmers’ markets in the southeastern United States. During its initial launch, the business generated limited orders for its products. In the beginning there was a limited amount of advertising using social media, which consisted of establishing a Facebook page, posting notifications on the business's Facebook page, and posting notifications about the business to the owners’ personal contacts on Facebook. Despite establishing a web presence and utilizing social media in its first year of operations, Suzy Q's did not generate a significant number of orders and received very little revenue. The owners of Suzy Q's, our client, established a goal to generate at least $700 per month in revenue for the calendar year 2015. Our analysis of the business revealed that the managers and employees had the skills needed to perform the work, but the lack of orders presented an obstacle to achieving their business goals. After completing a performance analysis, we recommended that Suzy Q's establish a single online presence, implement a marketing effort, establish a local presence, create a dedicated studio space, and create a formal business plan. It was our belief that Suzy Q's had the potential to reach its goals set for 2015 and beyond if these solutions were implemented.  相似文献   

Editorial     

Jér?me Rossier 《International Journal for Educational and Vocational Guidance》2012,12(3):167-170

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Book Reviews     

Ted Goodhew  Professor R. F. Dearden    John Alcock  Caroline Lodge 《Pastoral Care in Education》2013,31(3):231-240

Ted Goodhew, T.R.I.S.T. Advisory Teacher, Berkshire County Council, ‘New Directions in Pastoral Care’, Edited by Peter Lang & Michael Marland, 1985 Blackwell —

Professor R. F. Dearden, University of Birmingham, Profiles and Records of Achievement, Patricia Broadfoot (ed) 1986 Holt, Rinehart and Winston £6.50 paperback

Pat Salder, Education for Capability, Ed Tyrrell Burgess N. F. E. K./Nelson 1986 £10.95

John Alcock, University of Warwick, Solo Monologues for Drama,John Goodwin and Bill Taylor 1985 Edward Arnold Ltd £2.15

Caroline Lodge, White Hart Lane School, London, Sharing,Beryl Heather FPA Education Unit 1984 52pp £3.50  相似文献   

“Forget birth pains,we haven't got past the conception stage yet”. A reply to Frank Coffield's ‘Britain's continuing failure to train: the birth pangs of a new policy’     

Caroline Lloyd  Jonathan Payne 《教育政策杂志》2013,28(5):563-568

This article is a response to Frank Coffield's recent reflections in this journal on the Performance and Innovation Unit's project on workforce development in Britain. It questions the extent to which the PIU's findings represent a ‘new understanding’ of the UK's skills problem and asks why academics have been so reluctant to spell out what a demand‐side strategy for tackling the problem would involve.  相似文献