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Rimi Shukla Kiran Anand K. M. Prabhu P. Suryanarayana Murthy 《Indian journal of clinical biochemistry : IJCB》1995,10(1):14-18
The hypocholesterolemic effect of the water extract of the bark ofFicus bengalensis was investigated in 3 groups of rabbits, 5 in each group. Group 1 rabbits served as healthy controls and were fed with groundnut oil 1 ml/kg body wt. (bw) for five weeks. Groups 2 and 3 were made hypercholesterolemic by feeding orally cholesterol suspended in groundnut oil (1 ml/kg bw) at a dose of 100 mg/kg bw/day. Group 2 animals (untreated) continued to get the same amount of cholesterol for another four weeks. Group 3 animals received water extract of the bark (50 mg/kg bw/day) in addition to cholesterol as above. At the end of the 5th week, water extract not only prevented the elevation of serum cholesterol in the treated animals (Group 3) but also brought down its level to 160±14 mg% as compared to untreated animals (Group 2) 290±42 mg%. There was improvement in other parameters of lipid profile namely HDL & LDL+VLDL cholesterol and triacylglycerol. 相似文献
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Pushpa P. Durgawale P. S. Shukla Shubhangi D. Sontakke P. G. Chougule 《Indian journal of clinical biochemistry : IJCB》2001,16(1):110-112
In the present study the property of lectin agglutination in blood on normal and different cancer patients has been observed.
The purifiedSynadenium grantii root lectin was non blood group specific and its utility as a diagnostic tool in malignancy was studied. Hemagglutination
(units/ml) of red blood cells of different types of cancer was compared with the normal control's red blood cells. Out of
113 total cancer patients, only a group of 29 breast cancer patients showed significant increase in titre value (P<0.05) compared
to normal control. 相似文献
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Vitamin C in Disease Prevention and Cure: An Overview 总被引：1，自引：0，他引：1
Shailja Chambial Shailendra Dwivedi Kamla Kant Shukla Placheril J. John Praveen Sharma 《Indian journal of clinical biochemistry : IJCB》2013,28(4):314-328
The recognition of vitamin C is associated with a history of an unrelenting search for the cause of the ancient haemorrhagic disease scurvy. Isolated in 1928, vitamin C is essential for the development and maintenance of connective tissues. It plays an important role in bone formation, wound healing and the maintenance of healthy gums. Vitamin C plays an important role in a number of metabolic functions including the activation of the B vitamin, folic acid, the conversion of cholesterol to bile acids and the conversion of the amino acid, tryptophan, to the neurotransmitter, serotonin. It is an antioxidant that protects body from free radical damage. It is used as therapeutic agent in many diseases and disorders. Vitamin C protects the immune system, reduces the severity of allergic reactions and helps to fight off infections. However the significance and beneficial effect of vitamin C in respect to human disease such as cancer, atherosclerosis, diabetes, neurodegenerative disease and metal toxicity however remains equivocal. Thus further continuous uninterrupted efforts may open new vistas to understand its significance in disease management. 相似文献
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An institutional repository is a system for dissemination and stewardship of the intellectual life and scholarship of an institution. It has become a new way for the institutions to contribute to the broader world of scholarship (Giesecke, 2011). In spite of the global recognition of institutional repositories as an open access scholarly communication channel, institutional repositories are still struggling with the problem of non-participation from contributors in developing countries like India. This study conveys the results of a survey conducted at a minority university of India. The study is an expression of the opinion of 542 faculty members and research scholars pertaining to the possible implications of institutional repositories on their professional and publishing practices. The study is undertaken to: Determine the level of awareness of institutional repository among contributors; identify the reasons for participation and non-participation of contributors; examine the implications of institutional repository on contributors professional and publishing practices; analyze the major obstacles/hindrances in the growth of an institutional repository; and suggest measures for better implementation and development of an institutional repository in future. With the help of the statistical techniques such as chi-square test and weighted mean the study resulted that the majority of the contributors are well aware about the concept of institutional repository, the majority of contributors have not deposited in an institutional repository so far, long term preservation of research materials is the first ranked reason for participation in an institutional repository, copyright and plagiarism concern is the main reason behind contributors’ non-participation in institutional repository, increased accessibility of research output is the major implication of the institutional repository on contributors professional practices, saved cost of publishing in a journal is the biggest implication of institutional repository on contributors publishing practices, and contributors demand more control on ownership, access and security in future for an institutional repository. This article is aimed at the institutions that report low-use and low-deposit repositories. It may be used to convince the contributors about the value of institutional repositories, importance of participating in an institutional repository and possible implications on their professional and publishing practices. The study is also intended at the management of the institutions to take notice of the contributors’ demands for future participation and develop policies accordingly for removing major barriers in the growth of institutional repositories and improving contributions and quality of content in the institutional repositories. 相似文献
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Sarah Lindstrom Johnson Ray E. Reichenberg Kathan Shukla Tracy E. Waasdorp Catherine P. Bradshaw 《Educational Measurement》2019,38(4):99-107
The U.S. government has become increasingly focused on school climate, as recently evidenced by its inclusion as an accountability indicator in the Every Student Succeeds Act. Yet, there remains considerable variability in both conceptualizing and measuring school climate. To better inform the research and practice related to school climate and its measurement, we leveraged item response theory (IRT), a commonly used psychometric approach for the design of achievement assessments, to create a parsimonious measure of school climate that operates across varying individual characteristics. Students (n = 69,513) in 111 secondary schools completed a school climate assessment focused on three domains of climate (i.e., safety, engagement, and environment), as defined by the U.S. Department of Education. Item and test characteristics were estimated using the mirt package in R using unidimensional IRT. Analyses revealed measurement difficulties that resulted in a greater ability to assess less favorable perspectives on school climate. Differential item functioning analyses indicated measurement differences based on student academic success. These findings support the development of a broad measure of school climate but also highlight the importance of work to ensure precision in measuring school climate, particularly when considering use as an accountability measure. 相似文献
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Attitudes and concerns of pre-service teachers regarding inclusion of students with disabilities into regular schools in Pune,India 总被引：1，自引：1，他引：0
Umesh Sharma Dennis Moore Sanjeev Sonawane 《Asia-Pacific Journal of Teacher Education》2009,37(3):319-331
Attitudes and concerns of pre-service teachers regarding implementation of inclusive education were examined. The participants consisted of 480 pre-service teachers enrolled in a one year Bachelor of Education (B.Ed) program at Pune University, in the state of Maharashtra. The results of the study showed that participants had somewhat negative attitudes and a moderate degree of concern regarding the inclusion of students with disabilities in their classes. Participants with higher level of education (i.e. postgraduate degrees) were found to have significantly more positive attitudes compared to their counterparts. Perceived level of confidence in teaching students with disabilities was also associated with lower degree of concerns amongst participants. The results are discussed with possible implications for university educators and policy makers. 相似文献
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Abbas Ali Mahdi Anu Chandra Raj Kumar Singh Sanjeev Shukla L. C. Mishra Sohail Ahmad 《Indian journal of clinical biochemistry : IJCB》2003,18(2):8-15
In the present study the antioxidative potential ofMomordica charantia, Azadirachta indica, Allium sativum andOcimum sanctum was assessed in streptozotocin induced diabetic rats. Lipid peroxide levels were also measured in normal, diabetic and treated
animals. Malondialdehyde (MDA) levels were significantly higher and antioxidant activity was found low in diabetic groups
as compared to the control groups, and significant alteration in both the MDA levels and antioxidant activity was also observed
when the above herbal hypoglycemic agents were given to diabetic rats. On the basis of our results we conclude thatM. charantia, A. indica, A. sativum andO. sanctum are not only useful in controlling the lipid peroxide levels but are also helpful in further strengthening the antioxidant
potential. 相似文献