Stochastic stability analysis of piecewise homogeneous Markovian jump neural networks with mixed time-delays     

Zheng-Guang Wu  Ju H. Park  Hongye Su  Jian Chu 《Journal of The Franklin Institute》2012,349(6):2136-2150

In this paper, the problem of stochastic stability analysis is considered for piecewise homogeneous Markovian jump neural networks with both discrete and distributed delays by use of linear matrix inequality (LMI) method. Based on a Lyapunov functional that accounts for the mixed time-delays, a delay-dependent stability condition is given, which is formulated by LMIs and thus can be easily checked. Some special cases are also investigated. Finally, a numerical example is given to show the validness of the proposed result.  相似文献   

Increased Homocysteine Level in Indian Sickle Cell Anemia Patients     

S. Pandey  H. R. Pandey  R. M. Mishra  Sw. Pandey  R. Saxena 《Indian journal of clinical biochemistry : IJCB》2012,27(1):103-104

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Are hsCRP Levels and LDL/HDL Ratio Better and Early Markers to Unmask Onset of Dyslipidemia and Inflammation in Asymptomatic Subclinical Hypothyroidism?     

Mala Mahto  Baidarbhi Chakraborthy  Srinivas H. Gowda  Harneet Kaur  Gaurav Vishnoi  Pramod Lali 《Indian journal of clinical biochemistry : IJCB》2012,27(3):284-289

The implications of subclinical hypothyroidism (SCH) are many amongst which the most important is progression to overt hypothyroidism. Other debatable aspects are its association with cardiovascular risk, neuromuscular and psychiatric dysfunction, increased predisposition to developing metabolic syndrome and an underlying pro-inflammatory state. We aimed to study the lipid profile, lipoprotein(a) [Lp(a)] and hsCRP levels and insulin resistance in a group of patients with SCH in a referral hospital and see if any significant differences exist between them and euthyroids. This is a case–control study where the selection of controls and cases was based on the thyroid profile. Subjects were selected on their visit to clinical biochemistry lab for thyroid function tests. 33 euthyroids were taken as controls (Group I) and 38 patients comprising of subclinical hypothyroids were grouped as cases (Group II). Serum thyroid stimulating hormone (TSH) was in the range of 0.5–5.0 mIU/L for euthyroids and for subclinical hypothyroids the concentration of TSH was more than 5 mIU/L. The concentration of tri-iodothyronine (T₃) and thyroxine (T₄) were in normal reference range in both the groups. Individual lipid profile parameters failed to show a significant p value between cases and controls. The LDL/HDL ratio was highly significant (p value < 0.0001) and hsCRP was also statistically between the two groups (p value = 0.0054). Lp(a) and insulin resistance did not differ significantly. SCH is a common disorder that frequently progresses to overt hypothyroidism. This study underlines the importance of LDL/HDL ratio rather than measurement of individual lipid profile parameters in bringing to light the dyslipidemic state associated with SCH. Moreover the use of hsCRP to detect an underlying pro-inflammatory state in SCH can also be emphasized.  相似文献   

Social information processing and coping strategies of shy/withdrawn and aggressive children: does friendship matter?     

Burgess KB  Wojslawowicz JC  Rubin KH  Rose-Krasnor L  Booth-LaForce C 《Child development》2006,77(2):371-383

The primary objectives of this investigation were to examine the attributions, emotional reactions, and coping strategies of shy/withdrawn and aggressive girls and boys and to examine whether such social cognitions differ within the relationship context of friendship. Drawn from a sample of fifth and sixth graders (M age = 10.79 years; SD = .77), 78 shy/withdrawn, 76 aggressive, and 85 control children were presented with hypothetical social situations that first involved unfamiliar peers, and then a mutual good friend. Results revealed group and gender differences and similarities, depending on the relationship context. From our findings emerges a central message: friends' involvement during interpersonal challenges or stressors mitigates children's attributions, emotions, and coping responses.  相似文献   

Revisiting the association between reading achievement and antisocial behavior: new evidence of an environmental explanation from a twin study     

Trzesniewski KH  Moffitt TE  Caspi A  Taylor A  Maughan B 《Child development》2006,77(1):72-88

Previous studies have reported, but not explained, the reason for a robust association between reading achievement and antisocial behavior. This association was investigated using the Environmental Risk (E-Risk) Longitudinal Twin Study, a nationally representative 1994-1995 birth cohort of 5- and 7-year-olds. Results showed that the association resulted primarily from environmental factors common to both reading and antisocial behavior and was stronger in boys. Environmental factors also explained the relation between reading disability and conduct disorder. Leading candidate environmental risk factors weakly mediated the association. For boys the best explanation was a reciprocal causation model: poor reading led to antisocial behavior, and vice versa. In contrast, the relation between reading achievement and attention deficit hyperactivity disorder was best explained by common genetic influences.  相似文献   

什么是世界一流大学   总被引：4，自引：0，他引：4  

韩立文  程栋昱  欧冬舒 《北京大学教育评论》2006,4(4):101-129

世界上很多发展中国家正致力于探索如何建立世界一流的大学。然而,对“世界一流”这个概念至今还没有一致的解释。本文尝试对这一概念进行可操作化的定义,首先在概括有关世界一流大学的发言和文章的基础上,回顾世界一流大学的有关特点;其次,本文通过建立回归模型,分析影响大学排名的决定因素。如果排名靠前的大学可以被认为是达到了世界水平,那么对排名的决定因素进行分析将可以预测世界一流大学的决定因素。  相似文献   

Inactivation of infectious bursal disease virus by binary ethylenimine and formalin   总被引：1，自引：0，他引：1  

Habib M  Hussain I  Fang WH  Rajput ZI  Yang ZZ  Irshad H 《Journal of Zhejiang University. Science. B》2006,7(4):320-323

In this experiment conducted to study the inactivation dynamics of infectious bursal disease virus （IBDV） by binary ethylenimine （BEI） in comparison with formalin, IBDV was isolated from the bursa of infected chickens and its confirmation was done by agar gel precipitation test. Viral suspensions were subjected to inactivation with BEI and formalin for pre-set time in- tervals. BEI was employed at concentrations of 0.001 and 0.002 mol/L while formalin was used at 0.1% and 0.2%. Sampling was done at 6, 12, 24, 36 and 48 h of incubation and samples were tested for their inactivation status in 9-day-old embryonated eggs and 3-week-old broiler chickens. IBDV was completely inactivated by 0.001 and 0.002 mol/L BEI after 36 h of incubation at 37℃, whereas formalin at 0. 1% and 0.2% concentrations inactivated IBDV in 24 h.  相似文献   

How golden is silence? Teaching undergraduates the power and limits of RNA interference   总被引：1，自引：1，他引：0  

Kuldell NH 《CBE life sciences education》2006,5(3):247-254

It is hard and getting harder to strike a satisfying balance in teaching. Time dedicated to student-generated models or ideas is often sacrificed in an effort to “get through the syllabus.” I describe a series of RNA interference (RNAi) experiments for undergraduate students that simultaneously explores fundamental concepts in gene regulation, develops cutting-edge laboratory skills, and embraces student-directed learning. Students design a small interfering RNA (siRNA) against luciferase, add it to cells expressing this gene, and then quantitatively assess the siRNA's effect on both intended and unintended targets, using a luciferase assay and a DNA microarray. Because both RNAi and microarray technologies are relatively new, with no clear consensus on their analysis or limitations, students are encouraged to explore different approaches to the design of their reagents and interpretations of their data. The ability to creatively formulate a hypothesis-driven experimental approach to a scientific question and to critically evaluate collected data is stressed. Equally important, this experiment emphasizes how modern scientific ideas emerge, are debated, tested, and decided.  相似文献   

Finding related sentence pairs in MEDLINE     

Smith LH  Wilbur WJ 《Information Retrieval》2010,13(6):601-617

We explore the feasibility of automatically identifying sentences in different MEDLINE abstracts that are related in meaning. We compared traditional vector space models with machine learning methods for detecting relatedness, and found that machine learning was superior. The Huber method, a variant of Support Vector Machines which minimizes the modified Huber loss function, achieves 73% precision when the score cutoff is set high enough to identify about one related sentence per abstract on average. We illustrate how an abstract viewed in PubMed might be modified to present the related sentences found in other abstracts by this automatic procedure.  相似文献   

禾本科植物幼苗性状的聚类分析     

韩建国  H. T. Clifford  贾慎修  王培 《中国科学院研究生院学报》1993,31(6):517-532

本文用201种禾本科植物幼苗的60个形态和解剖性状进行了聚类分析，将禾本科植物分为四个大类(一级聚合单位)—狐茅类(Festucoid)、黍类(Panicoid)，竹类(Bambusoid)和画眉草类(Eragrostidoid)。这四类基本上与分类系统中的亚科相吻合，只是芦竹亚科植物的幼苗分散聚到了其它类中。推测芦竹亚科是一个比较原始的类群，狐茅亚科、黍亚科和画眉草亚科可能是在芦竹亚科的基础上进化而来的。  除个别种外，大多数同属的种在较低的聚合水平上聚在一起，超族在亚聚合单位中基本上能够反映出来。  研究证明禾本科植物的幼苗性状在禾本科植物分类中具有重要的分类学意义。  相似文献