NSCLC患者血管内皮生长因子(VEGF)的表达及其临床意义     

陈跃华  徐原科 《铜陵职业技术学院学报》2007,6(3):32-34

目的:探讨肺癌血管内皮生长因子(VEGF)的表达与非小细胞肺癌临床病理特征的关系及其临床意义。方法:用免疫组化SP法检测87例非小细胞肺癌(non small cell lung cancer,NSCLC)组织、17例良性肺疾病和6例正常肺组织中VEGF的表达。结果:在NSCLC组织中血管内皮细胞VEGF的高表达率62.69%(54/87),良性肺疾病和正常肺组织中的高表达率4.35%(1/23),两者比较有显著性差异,P<0.01;低分化NSCLC细胞胞质VEGF的高表达率90.63%(29/32)明显高于高、中分化NSCLC细胞胞质的高表达率45.45%(25/55),P<0.01;在有淋巴结转移的NSCLC细胞胞质中VEGF高表达率90.20%(46/51),明显高于无淋巴结转移组的高表达率22.22%(8/36),P<0.01;NSCLC胞质中VEGF蛋白高表达率与临床分期密切相关,Ⅲ、Ⅳ期高于Ⅰ、Ⅱ期,分别是87.50%(49/56),16.13%(5/31),P<0.01。结论:VEGF高表达与NSCLC的生物学行为密切相关,它的高表达提示NSCLC患者预后不良。  相似文献   

我国信贷传导渠道受阻的原因分析及对策建议     

冯友钊  李伟 《荆州师范学院学报》2005,28(3):73-76

造成信贷传导渠道日趋萎缩的主要原因有二：一是巨大存差的存在；二是资金分布的结构性矛盾。要从根本上解决该问题，政府相关部门、中央银行和商业银行应相互协调，促使信贷传导渠道的疏通。  相似文献   

视觉文化与当代小说中女性形象的变迁     

徐巍 《咸阳师范学院学报》2005,20(5):70-72

视觉文化不仅为我们带来了大量的影像,更为重要的是,它颠覆了人们传统以来的世界观和生活方式。从根本上讲,这种变化是从以语言为中心的意象转向以视觉为中心的形象。在当代小说中,则无疑呈现出一些新的审美风貌。  相似文献   

Promoting cognitive and social aspects of inquiry through classroom discourse     

Hui Jin  Xin Wei  Peiran Duan  Yuying Guo  Wenxia Wang 《International Journal of Science Education》2016,38(2):319-343

We investigated how Chinese physics teachers structured classroom discourse to support the cognitive and social aspects of inquiry-based science learning. Regarding the cognitive aspect, we examined to what extent the cognitive processes underlying the scientific skills and the disciplinary reasoning behind the content knowledge were taught. Regarding the social aspect, we examined how classroom discourse supported student learning in terms of students' opportunities to talk and interaction patterns. Our participants were 17 physics teachers who were actively engaged in teacher education programs in universities and professional development programs in local school districts. We analyzed one lesson video from each participating teacher. The results suggest both promises and challenges. Regarding the cognitive aspect of inquiry, the teachers in general recognized the importance of teaching the cognitive processes and disciplinary reasoning. However, they were less likely to address common intuitive ideas about science concepts and principles. Regarding the social aspect of inquiry, the teachers frequently interacted with students in class. However, it appeared that facilitating conversations among students and prompting students to talk about their own ideas are challenging. We discuss the implications of these findings for teacher education programs and professional development programs in China.  相似文献   

Reuse of clips in cartoon animation based on language instructions     

魏宝钢  朱文浩  于金辉 《浙江大学学报(A卷英文版)》2006,7(2):123-129

INTRODUCTION tic in-betweening techniques have been proposed during the past 30 years (for a comprehensive review of automatic in-betweening methods, please refer to (Yu and Patterson, 1997; Gotsman and Surazhsky, 2001)), their use in computer aided systems is some- how limited to dealing with local movements only (Yu and Patterson, 1997), because exaggerated drawings used in cartoon animations follow animation princi- ples and do not respect the geometry (Patterson and Willis, 1994) tha…  相似文献   

结构主义学习理论及其在教与学中的应用     

金臣  金坤 《承德师专学报》2006,26(1):56-57

人类进入21世纪以来,随着信息技术的飞速发展,结构主义学习理论对人类教育活动的影响显得越来越大,基于结构主义的教学模式更加符合我们对未来要培养“学会学习”、“学会创造”、“学会合作”等教育目标的要求,作者从结构主义学习理论产生入手．对结构主义学习理论及其在教与学中的应用进行了阐述和讨论。  相似文献   

基于Web模式可移植性训练系统的设计与实现   总被引：2，自引：0，他引：2  

宋春晖雷景生  陈焕东 《海南师范学院学报》2005,18(2):141-144

三层结构模式在Web应用系统中广泛应用，但也存在不足之处：系统对网络环境完全依赖，网络资源利用不平衡．因此，从一个基于Web模式的训练教学系统的设计和实现过程，对Web三层结构提出了调整改进措施，在设计中构建了具有一定逻辑功能的Web页面数据单元，从而实现数据的重用性和系统设计的可移植性，并有效地解决了Web三层结构系统的不足之处．  相似文献   

返本归真自娱自乐--北爱尔兰早期教育课程简介     

陈光春 《沙洋师范高等专科学校学报》2004,5(1):81-83

为了分析儿童自发性活动与成人指导性活动相关的早期教育课程 ,北爱尔兰教研人员在 71所不同类型早期教育机构开展了调查活动。主要调查早期教育机构全学年中具有代表性的一天的课堂活动。调查记载儿童参与的活动项目、活动内容、活动设施、参与儿童活动的成人和父母数量以及成人参与儿童活动的时间。调查结果表明 :在大多数接待班 ,早期教育儿童课程偏重于成人指导性方法 ;而大多数日托所、娱乐班、保育学校更倾向采用儿童自发性方法  相似文献   

薮北茶的组织培养   总被引：7，自引：0，他引：7  

张娅婷  张伟 《周口师范学院学报》2004,21(5):74-76

用薮北茶带腋芽的茎段作为外植体进行组织培养获得再生植株,并建立快速无性繁殖系.以MS为基本培养基,附加各种浓度的植物激素.试验结果表明,芽增殖培养基为1/2MS 1.0mg/L BA 0.2mg/L IBA;生根壮苗培养基为1/4MS 0.5mg/L BA 0.1mg/L IBA 0.01mg/L Al3 .  相似文献   

Enhancing cellular immune response to HBV M DNA vaccine in mice by codelivery of interleukin-18 recombinant     

陈建忠  朱海红  刘克洲  陈智 《浙江大学学报(A卷英文版)》2004,5(4):467-471

Objective: To investigate the effect of interleukin-18 (IL-18) on immune response induced by plasmid encoding hepatitis B virus middle protein antigen and to explore new strategies for prophylactic and therapeutic HBV DNA vaccines. Methods: BALB/c mice were immunized with pCMV-M alone or co-immunized with pcDNA3-18 and pCMV-M and then their sera were collected for analysing anti-HBsAg antibody by ELISA; splenocytes were isolated for detecting specific CTL response and cytokine assay in vitro. Results: The anti-HBs antibody level of mice co-immunized with pcDNA3-18 and pCMV-M was slightly higher than that of mice immunized with pCMV-M alone, but there was not significantly different (P>0.05). Compared with mice injected with pCMV-M, the specific CTL cytotoxity activity of mice immunized with pcDNA3-18 and pCMV-M was significantly enhanced (P<0.05) and the level of IFN-γ in supernatant of splenocytes cultured with HBsAg in vitro was significantly elevated (P<0.05) while the level of IL-4 had no significant difference (P>0.05). Conclusion: The plasmid encoding IL-18 together with HBV M gene DNA vaccines may enhance specific TH1 cells and CTL cellular immune response induced in mice, so that IL-18 is a promising immune adjuvant.  相似文献