Pure word deafness associated with extrapontine myelinolysis     

Zhu RJ  Lv ZS  Shan CL  Xu MW  Luo BY 《Journal of Zhejiang University. Science. B》2010,11(11):842-847

Extrapontine myelinolysis and pure word deafness are very uncommon disorders. Here, we report a case of a 19-year-old woman who suffered from osmotic demyelination syndrome with coincidence of typical pure word deafness. As a consequence of rapid correction of hyponatremia, the patient demonstrated an initial onset of cortical deafness, and then progressed to generalized auditory agnosia, which eventually developed into confined verbal auditory agnosia (pure word deafness). Bilateral extrapontine myelinolysis was confirmed using brain magnetic resonance imaging. This case suggests that verbal and nonverbal stimuli may involve separate thalamocortical pathways.  相似文献   

《去吧,摩西》中的人物命名类比研究     

付纬航  李良沛 《昭通师范高等专科学校学报》2010,32(1):51-53,72

福克纳从听觉联系,读音联系,形态联系,语义联系,文学或神话典故的联系对小说中的人物进行命名,类比强化了人物命名与人物塑造的关系,揭示了人物塑造与小说主题的内在关系,创造出独特的艺术形式之美。  相似文献   

Association between 11beta-hydroxysteroid dehydrogenase type 1 gene polymorphisms and metabolic syndrome in Bosnian population   总被引：1，自引：0，他引：1  

Dujic T  Bego T  Mlinar B  Semiz S  Malenica M  Prnjavorac B  Ostanek B  Marc J  Causevic A 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2012,22(1):76-85

Introduction:

The enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) catalyzes the conversion of the hormonally inactive cortisone to active cortisol, thus facilitating glucocorticoid receptor activation in target tissues. Increased expression of 11β-HSD1 in adipose tissue has been associated with obesity and insulin resistance. In this study, we investigated the association of two 11β-HSD1 gene (HSD11B1) polymorphisms with the metabolic syndrome (MetS) and its characteristics in the Bosnian population.

Materials and methods:

The study included 86 participants: 43 patients diagnosed with MetS and 43 healthy controls. Subjects were genotyped for two HSD11B1 gene polymorphisms: rs846910: G>A and rs45487298: insA, by the high resolution melting curve analysis. Genotype distribution and an influence of genotypes on clinical and biochemical parameters were assessed.

Results:

There was no significant difference in the mutated allele frequencies for the two HSD11B1 gene polymorphisms between MetS patients and controls. In MetS patients, no significant associations between disease-associated traits and rs45487298: insA were found. Regarding rs846910: G>A variant, heterozygous patients (G/A) had significantly lower systolic (P = 0.017) and diastolic blood pressure (P = 0.015), lower HOMA-IR index (P = 0.011) and higher LDL-cholesterol levels (P = 0.049), compared to the wild-type homozygotes. In the control group, rs45487298: insA polymorphism was associated with lower fasting plasma insulin levels (P = 0.041), lower homeostasis model assessment insulin resistance (HOMA-IR) index (P = 0.041) and lower diastolic blood pressure (P = 0.048). Significant differences between rs846910: G>A genotypes in controls were not detected. Haplotype analysis confirmed the association of rs45487298: insA with markers of insulin resistance in the control subjects.

Conclusions:

Our results indicate that a common rs45487298: insA polymorphism in HSD11B1 gene may have a protective effect against insulin resistance.  相似文献   

Lack of Circadian Pattern of Serum TNF-α and IL-6 in Patients with Fibromyalgia Syndrome     

Ghizal Fatima  Abbas Ali Mahdi  Siddharth Kumar Das  Baby Anjum  Nar Singh Verma  Puneet Kumar  Ragini Shrivastava 《Indian journal of clinical biochemistry : IJCB》2012,27(4):340-343

The present study was designed to test the hypothesis of a circadian variation in circulating levels of tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) in women with fibromyalgia syndrome (FMS). Serum levels of IL-6 and TNF-α were measured at 4 h intervals of the day in 50 women with FMS satisfying American College of Rheumatology criteria for FMS (age 36.68 ± 9.89) as well as 50 healthy control women (age 32.82 ± 10.53). Serum TNF-α levels were substantially increased in patients with FMS but showed no circadian variation. In contrast, no difference in the levels of IL-6 was found. Moreover, there was also no circadian variation in both the groups of patients and controls. We conclude that no circadian pattern exists in the circulating levels of serum IL-6 and TNF-α in patients with FMS, although TNF-α levels are found raised in patients with FMS.  相似文献   

Asperger syndrome and the English curriculum: addressing the challenges     

HILARY HARBINSON  JOY ALEXANDER 《Support for Learning》2009,24(1):11-18

A major criterion for the diagnosis of Asperger syndrome is an impairment of the imagination. This article focuses on the specific difficulties that students with Asperger syndrome have with the imaginative content of the English curriculum. It examines the problems with reading and writing imaginatively of a group of students with AS in a secondary school mainstream setting. Various strategies and interventions are considered and discussed which could aid their understanding and learning in relation to the imaginative element of the English curriculum. While acknowledging that this is an area of real difficulty for these students, recommendations include: treating students with AS as individuals; using a small group setting; providing support through structured frameworks.  相似文献   

循序渐进运动疗法治疗慢性疲劳综合征的相关研究   总被引：1，自引：0，他引：1  

卓杰先  谷礼燕 《北京体育大学学报》2007,30(6):801-802,808

目的:研究循序渐进运动疗法对慢性疲劳综合征的效果.方法:70名患者随机分为两组,运动组和对照组.运动组进行循序渐进锻炼,对照组进行休息.记录其治疗前后睡眠时间,生活质量问卷评分,心理躯体症状问卷评分.结果:循序渐进运动能够循序渐进锻炼疗法能够有效的改善慢性疲劳综合征患者的疲劳症状,延长其睡眠时间,眼和耳,肌肉骨骼系统,神经系统的症状明显好转,生活质量得到提高.  相似文献   

散打课运动损伤产生的原因及预防   总被引：5，自引：0，他引：5  

范谋德 《福建体育科技》2002,21(3):54-55,58

通过对福建公安高等专科学校 2 0 0 0级二大队在散打普修课结束后的问卷调查 ,对运动损伤数据进行统计、分析 ,结果表明散打课的运动损伤具有“小外伤多 ,严重损伤少”的特点 ,从损伤部位看以小腿 (包括膝关节 )和足趾部的挫伤、碰伤发生率较高 ,在此基础上 ,论述了预防、减少散打课运动损伤的几种方法。  相似文献   

Naturalistic intervention for Asperger syndrome – a case study     

Serene Hyun‐Jin Choi  Timo A. Nieminen 《British Journal of Special Education》2008,35(2):85-91

On the basis of their cognitive abilities, children with Asperger syndrome are attractive candidates for inclusive education and, in Australia, most are in integrated settings. However, social interaction between children with Asperger syndrome and their peers remains problematic, with the children with Asperger syndrome often being left alone despite being among or near classmates. For classroom teachers, effective interventions in terms of class management are critical to facilitate positive social interaction between these two groups of children, and case studies can tell us a great deal about what works. In practice, a combination of intervention techniques may be best, in case a single one is ineffective, and in order to take advantage of potential synergies. In this article, Serene Choi, of the School of Education at the University of Newcastle (Australia) and Timo Nieminen, of the Centre for Biophotonics and Laser Science in the Department of Physics at the University of Queensland, report a naturalistic multiple-component intervention used to develop the social skills of a boy with Asperger syndrome in a mainstream school in Australia. This combined intervention, making use of social stories, simple peer modelling and individual lessons, appears to be a practical teaching method for inclusive education.  相似文献   

运动性脾气虚证研究现状与展望   总被引：1，自引：0，他引：1  

林文弢  黄森  翁锡全  陈晓彬 《广州体育学院学报》2003,23(6):39-41

采用献资料法，综述了近年来有关运动性脾气虚证的诊断标准、动物实验和临床研究现状，分析了目前研究中存在的问题，提出今后的研究方向，为运动性脾气虚证本质的系统研究提供了参考。  相似文献   

弹拨手法治疗运动员“梨状肌综合症”的临床体会     

曾燕生 《湖北体育科技》2009,28(6):718-719,709

运动员髋关节外展、外旋或下蹲转直立的动作可使梨状肌过度牵拉出现＂梨状肌综合征＂。通过弹拨手法针对性的处理,可解除梨状肌的痉挛并松解粘连,从而使坐骨神经压迫症状得到明显的缓解,疗效优于针灸、理疗、封闭等治疗手段。  相似文献