Cell therapy in congestive heart failure   总被引：5，自引：0，他引：5  

Tao ZW  Li LG 《Journal of Zhejiang University. Science. B》2007,8(9):647-660

Congestive heart failure （CHF） has emerged as a major worldwide epidemic and its main causes seem to be the aging of the population and the survival of patients with post-myocardial infarction. Cardiomyocyte dropout （necrosis and apoptosis） plays a critical role in the progress of CHF; thus treatment of CHF by exogenous cell implantation will be a promising medical approach. In the acute phase of cardiac damage cardiac stem cells （CSCs） within the heart divide symmetrically and/or asymmetrically in response to the change of heart homeostasis, and at the same time homing of bone marrow stem cells （BMCs） to injured area is thought to occur, which not only reconstitutes CSC population to normal levels but also repairs the heart by differentiation into cardiac tissue. So far, basic studies by using potential sources such as BMCs and CSCs to treat animat CHF have shown improved ventricular remodelling and heart function. Recently, however, a few of randomized, double-blind, placebo-controlled clinical trials demonstrated mixed results in heart failure with BMC therapy during acute myocardial infarction.  相似文献   

Effect of a distal protection device on epicardial blood flow and myocardial perfusion in primary percutaneous coronary intervention   总被引：2，自引：0，他引：2  

Zhou BQ  Tahk SJ 《Journal of Zhejiang University. Science. B》2007,8(8):575-579

Objective: The beneficial effect of percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI) has been well established, but there is the problem of no-reflow phenomenon which is an adverse prognostic factor in primary PCI. In the present study the effect of a distal protection device (PercuSurge GuardWire; GW) on epicardial blood flow and myocardial perfusion was evaluated. Methods and Results: Patients with AMI were randomly divided into 2 groups, the GW and the control groups. The GW group included 52 patients with AMI who underwent primary PCI with GW protection and the control group included 60 patients who underwent primary PCI without GW protection. Epicardial blood flow in the infarct-related artery (IRA) and myocardial perfusion were evaluated according to the thrombolysis in myocardial infarction (TIMI) flow grade and the myocardial blush grade (MBG). We found TIMI score of 3 was obtained significantly more frequently in the GW group (96%) than in the control group (80%). The MBG score of 3 was obtained also significantly greater in the GW group (65%) than in the control group (33%). Conclusion: Primary PCI with GW protection can significantly improve epicardial blood flow and myocardial perfusion.  相似文献   

板栗枝干病害的发生与树势和立地条件关系的研究     

管斌 《安徽科技学院学报》2007,21(6):19-22

对5种不同病情的栗园与土壤深度、容重、树势和栗园小气候之间的关系进行了调查研究.结果表明:病害与土层深度呈负相关,与土壤容重呈正相关;不同的树势或病情对叶的生理及栗园生态均有一定程度的影响,进一步揭示了板栗枝干病害的发生发展规律.  相似文献   

中国疾病史研究的回顾与前瞻     

叶宗宝 《信阳师范学院学报(哲学社会科学版)》2011,31(6):128-132

中国疾病史研究最初是在医学史的脉络下展开的,目的在于总结和汲取前人应对疾病的历史经验。1980年代以后,随着医疗技术的发展,疾病史在医界中的地位渐趋边缘化,而非医界人士加入了研究队伍。虽然目前在疾病自然史、疾病社会史和疾病文化史方面已取得丰硕研究成果,但研究过于细琐,且视野不够宽广。及时吸收相关研究成果,沟通微观与宏观,是今后的发展趋势。  相似文献   

孟子的反求诸己     

杜真强  李葆华 《哈尔滨学院学报》2011,32(5):27-30

反求诸己,是贯穿《孟子》一书的主要哲学观念,是中国文化传统中思维指向与思维形式概括与准确的表述之一。理解与把握这种思维指向与思维形式,于当下的文化建设与个人修养,仍有十分重要的意义。孟子的反求诸己,直接源自孔子。反求诸己＂心＂,是孟子反求诸己的理论基础。如何对待＂横逆＂,是孟子于反求诸己的突出贡献。  相似文献   

孝感市老年人常见慢性病的调查分析     

周伟  张晶  陈漫  汪德忠  涂豆豆 《孝感职业技术学院学报》2011,(3):109-112

目的：调查孝感市老年人群常见疾病分布特征,为预防和保健措施提供依据。方法：对1785名55岁以上老年人进行问卷调查,获取常患疾病资料。结果：孝感市老年人群患病率较高的依次是高血压病（28．01％）,颈腰椎疾病（19．33％）、风湿病（12．32％）、心脏病（9．24％）。各疾病性别间差异无统计学意义（P〉0．05）,部分疾病在年龄、城乡、运动习惯间差异有统计学意义（P〈0．05）。结论：孝感市老年人群慢性疾病患病率较高,而且往往同时患有多种疾病,人均慢性病频率为98．04％（男性101．0％,女性93．88％）,严重影响老年人的生活质量,要引起社会的高度重视。  相似文献   

社区康复实训中心学生自主管理模式探析——以重庆城市管理职业学院社区康复实训中心为例     

李莉 《重庆职业技术学院学报》2011,20(3):1-3

根据社区康复实训中心管理的现状和存在的问题,提出以学生为主体的自主管理模式,让学生成为管理的主人,充分发挥学生的主观能动性,促进实训中心管理水平和实践教学质量的提高,培养学生的服务意识、责任意识,提升学生的自我管理能力,使他们能更快适应岗位需求。  相似文献   

Teacher Empathy and Attitudes Towards Individuals with Disabilities     

Monika Parchomiuk 《International Journal of Disability, Development & Education》2019,66(1):56-69

The article presents research results of a study aimed at determining the correlation between empathy understood as a personality disposition and general attitudes towards individuals with disability. The sample consisted of 300 special education teachers working with persons with intellectual disabilities in primary and secondary schools and institutions of rehabilitation, and 280 general education teachers working with able-bodied students in primary and secondary schools. Two instruments were used: Empathic Understanding of Other People Questionnaire, and the Scale of Attitudes towards Individuals with Disability. In the group of special education teachers, only Syndrome 2 of empathy was statistically significant for shaping the attitudes, whereas among teachers, Syndromes 1, 3 and 4 were significant. In Syndromes 1, 2 and 4, including the highest level of emotional, cognitive, motivational and communication aspects of empathy, the correlations were positive as expected. In the case of Syndrome 3, including the considerable level of cognitive empathy, the correlation was negative.  相似文献   

西安明城墙遗址主要病害勘察及成因分析     

黄四平  王肃 《咸阳师范学院学报》2011,26(6):39-42

对西安明城墙进行实地调查和资料调研后发现,明城墙主要存在盐分结晶引起的墙体泛白、墙体裂缝、表面风化、墙体掏蚀和彩绘层的起翘、脱落与模糊五种病害,并对其成因进行了分析,为古城墙保护提供了科学依据。  相似文献   

教师发展阶段理论综述及发展水平模型的构建     

郭光华  吴灵维 《重庆第二师范学院学报》2011,24(5):61-64

一、研究源起 教师的专业成熟要经过一个长期的发展过程,从一个新教师成长为一个合格的、优秀的教师乃至知名的教育家,不是一蹴而就的,就专业成熟的过程而言,需要经历一个发展阶段。因此,对教师成长的周期和规律的研究,有助于为教师指明个人的专业发展道路,为教师的专业学习和训练提供需要的基本内容。  相似文献