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411.
唐氏综合症患者的语言与短时记忆特点研究现状 总被引:1,自引:0,他引:1
唐氏综合症是一种常见的遗传疾病 ,国外对其研究深入广泛 ,在语言和记忆方面的研究也较为系统 ,但国内对该领域的研究却非常少见。本文将论述国外在唐氏综合症患者的语言和记忆方面的研究结论 ,以及干预和训练方面的研究成果 ,以便为国内研究提供借鉴和参考。 相似文献
412.
通过对颈椎综合征的含义、发病原因、临床分型等方面进行探讨,认为本病是一种涉及广泛、临床症状繁杂的常见病、多发病,且多见于中老年人,对100例颈椎综合征的病人采用牵引、手法按摩、中药及自我导引等综合疗法,其疗效较为满意、本法由于操作简便、疗效确切而便于临床推广使用. 相似文献
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414.
This article is based on language, memory andreading information gathered for a five yearfollow-up study of 30 children and adolescentswith Down syndrome, aged from 10 to 24 years atthe end of the study. At Time 1, 10individuals were classified as readers but byTime 2 this number had risen to 16. Readers significantly outperformed non-readerson tests of nonverbal ability, languagecomprehension and production, phonologicalmemory and phonological awarenesss. However,some of these differences could be accountedfor by readers' significantly lower hearingthresholds. Phonological memory and earlyletter knowledge at Time 1 were significantpredictors of reading scores for Time 2readers, after controlling for age, nonverbalability and corresponding Time 1 readingscores. There was no evidence that learning toread had a significant impact on later languagecomprehension, but early reading skills may besignificant predictors of MLU five years later,after controlling for age, nonverbal abilityand hearing. 相似文献
415.
This paper presents a review of currentknowledge concerning the reading skills ofchildren and adults with Williams syndrome. The paper begins by highlighting themethodological issues surrounding research onreading in atypical populations and discussesthe issue of comparison groups. It proceeds toreview evidence from studies that havedescribed the reading profile observed inWilliams syndrome in relation to the documentedcognitive and linguistic profile, andspecifically examines the relationship betweenreading and phonological skills. The paperadvocates a more dynamic developmental approachto the study of reading in atypical populations. 相似文献
416.
INTRODUCTION OF ACUTE LUNG IN- JURY/ACUTE RESPIRATORY DISTRESS SYN- DROME (ALI/ARDS) Acute lung injury (ALI) and its more severe form, the acute respiratory distress syndrome (ARDS) are syndromes of acute respiratory failure, which was defined by radiological (bilateral lung field infiltrates) and physiological (the ratio of arterial oxygen pres- sure and the inspiratory oxygen concentration, Pa O 2 /Fi O2≤300 mmHg for ALI and ≤200 mmHg for ARDS) criteria in… 相似文献
417.
Shang YP Xie XD Wang XX Chen JZ Zhu JH Tao QM Zheng LR 《Journal of Zhejiang University. Science. B》2005,6(7):626-630
Congenital long QT syndrome (LQTS) is a genetically heterogeneous disease in which six ion-channel genes have been identified. The phenotype-genotype relationships of the HERG (human ether-a-go-go-related gene) mutations are not fully understood. The objective of this study is to identify the underlying genetic basis of a Chinese family with LQTS and to characterize the clinical manifestations properties of the mutation. Single strand conformation polymorphism (SSCP) analyses were conducted on DNA fragments amplified by polymerase chain reaction from five LQT-related genes. Aberrant conformers were analyzed by DNA sequencing. A novel splice mutation in C-terminus of HERG was identified in this Chinese LQTS family, leading to the deletion of 11-bp at the acceptor splice site of Exon9 [Exon9 IVS del (-12→-2)]. The mutation might affect, through deficient splicing, the putative cyclic nucleotide binding domain (CNBD) of the HERG K channel. This mutation resulted in a mildly affected phenotype. Only the proband had a history of syncopes, while the other three individuals with long QT interval had no symptoms. Two other mutation carriers displayed normal phenotype. No sudden death occurred in the family. The 4 affected individuals and the two silent mutation carriers were all heterozygous for the mutation. It is the first splice mutation of HERG reported in Chinese LQTS families. Clinical data suggest that the CNBD mutation may be less malignant than mutations occurring in the pore region and be partially dominant over wild-type function. 相似文献
418.
阿斯贝格症儿童的评估与干预 总被引:2,自引:1,他引:2
阿斯贝格综合症 (Asperger’sSyndrome ,AS)是一种主要以社会交往困难 ,及异常的兴趣行为模式为特征的儿童广泛性发育障碍。其评估与儿童孤独症有所不同 ,但在干预与治疗上可参考孤独症的原则与方法。 相似文献
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420.
随着心理语言学的发展,有关心理词汇的研究也在不断升温.在博览各家学说的基础上,首先肯定了心理词汇意义的模糊本质以及造成这种模糊本质的主要原因,然后探讨了可以代表词汇基本意义的原型成员以及词汇意义的原型特征,最后,在心理词汇意义具有模糊性和原型性的基础上,提出了心理词汇的内部结构具有双重性的假设. 相似文献