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991.
ABSTRACT

The systematic review and meta-analysis evaluated the effect of aerobic, resistance and combined exercise on RMR (kCal·day-1) and performed a methodological assessment of indirect calorimetry protocols within the included studies. Subgroup analyses included energy/diet restriction and body composition changes. Randomized control trials (RCTs), quasi – RCTs and cohort trials featuring a physical activity intervention of any form and duration excluding single exercise bouts were included. Participant exclusions included medical conditions impacting upon RMR, the elderly (≥65 years of age) or pregnant, lactating or post-menopausal women. The review was registered in the International Prospective Register of Systematic Reviews (CRD 42,017,058,503). 1669 articles were identified; 22 were included in the qualitative analysis and 18 were meta-analysed. Exercise interventions (aerobic and resistance exercise combined) did not increase resting metabolic rate (mean difference (MD): 74.6 kCal·day-1[95% CI: ?13.01, 161.33], P = 0.10). While there was no effect of aerobic exercise on RMR (MD: 81.65 kCal·day-1[95% CI: ?57.81, 221.10], P = 0.25), resistance exercise increased RMR compared to controls (MD: 96.17 kCal·day-1[95% CI: 45.17, 147.16], P = 0.0002). This systematic review effectively synthesises the effect of exercise interventions on RMR in comparison to controls; despite heterogenous methodologies and high risk of bias within included studies.  相似文献   
992.
Children in kindergarten were randomly assigned to adaptive computerised counting or comparison interventions, or to a business-as-usual control group. Children in both intervention groups, including children with poor calculation skills at the start of the intervention, performed better than controls in the posttest. However the effects of training held in grade 1, playing serious counting games improving number knowledge and mental arithmetic performances, and playing serious comparison games, only enhanced the number knowledge proficiency in grade 1. The value of these short periods of intensive gaming in kindergarten are discussed as a look-ahead approach to enhance arithmetic proficiency.  相似文献   
993.
Duchenne muscular dystrophy (DMD) is a progressive genetic condition that affects both muscle and brain. Children with DMD are at risk of psycho‐social difficulties such as poor academic achievement and behavioural and socio‐emotional problems. This article by Janet Hoskin and Angela Fawcett, both from the University of Swansea, describes how 34 participants with DMD took part in a 36‐week online literacy intervention which was delivered in partnership between home and school. The key objective was to improve reading skill. Participants were re‐tested at 36 weeks for single word and text level reading, comprehension, fluency, processing and timed single word reading. Pre and post results indicated that children who followed the intervention for 36 weeks made significant improvement in their single word reading (p = <0.0001), timed single word reading (p = <0.0001) and text level reading (p = <0.004). They also made significant improvement in their fluency and comprehension scores. The results showed that children with DMD and related literacy difficulties benefit from a regular, structured and systematic synthetic phonics programme. With young people with DMD increasingly living into adulthood, early literacy intervention is particularly important to ensure optimum career and training opportunities.  相似文献   
994.
摘要:目的: 探讨心脏NRG1在间歇运动激活心梗(myocardial infarction,MI)大鼠心肌NRG1-PI3K/Akt通路抑制心肌细胞凋亡的作用。方法:雄性SD大鼠48只,随机分为假手术组(S),心梗安静组(MI),心梗+间歇运动组(ME),心梗+间歇运动+抑制剂组(MEA),每组12只。采用左冠脉前降支结扎法建立MI模型。S组手术仅穿线不结扎。ME组和MEA组在MI术后1wk进行跑台间歇运动。运动开始速度为10m/min运动10min后,速度逐渐增至25m/min×7 min,再以15 m/min×3min运动,之后依次交替进行。60min×1次/d,5d/1wk×8wk。训练结束后次日,腹腔麻醉,颈动脉插管测定LVSP、LVEDP及±dp/dtmax。之后开胸摘取心脏,进行组织学制片,Masson染色。荧光实时定量PCR测定心肌NRG1及其受体ErbB2/4表达。Western Blot法检测心肌NRG1、ErbB2/4、PI3K/Akt、Bcl-2和Bax蛋白含量。Caspase3表达及TUNEL检测观察分析心肌细胞凋亡情况。结果: MI组胶原容积百分比(CVF)和LVEDP较S组显著升高(P<0.01,P<0.01),LVSP和±dp/dtmax显著降低(P<0.01,P<0.01)。且MI后心肌ErbB4 mRNA表达显著降低(P<0.01),心肌NRG1、ErbB2和ErbB4蛋白表达显著降低(P<0.05,P<0.01,P<0.01),PI3K/Akt蛋白表达及Bcl-2/Bax比值显著降低(P<0.01,P<0.01),TUNEL阳性细胞数和Caspase3活力显著增加(P<0.01,P<0.01)。ME组CVF和LVEDP较MI组显著降低(P<0.01,P<0.01),LVSP和±dp/dtmax显著升高(P<0.01,P<0.01),心肌NRG1、ErbB2和ErbB4 mRNA及蛋白表达均显著增加(P<0.01,P<0.01,P<0.01),PI3K/Akt蛋白表达和Bcl-2/Bax比值显著增加(P<0.01,P<0.01),TUNEL阳性细胞数和Caspase3活力显著降低(P<0.01,P<0.01),且运动效应被抑制剂AG1478显著减弱。结论:间歇运动可通过激活心肌NRG1及其受体表达,上调PI3K/Akt蛋白表达,抑制心肌细胞凋亡和胶原过度增生,改善心功能。  相似文献   
995.
Little is known about the transmission of vibration to the head when using whole-body vibration (WBV) training machines. This paper investigates the effect of frequency and posture on the transmission of vibration from a vibrating plate to the head of standing people. Nine male participants were exposed to vertical vibration at nine frequencies in the range of 17–46 Hz and vibration acceleration in the range of 7.85–18.64 m/s2 (peak). The participants adopted four standing postures described as standing with locked knee (LK), bent knee (BK), one leg (OL), and one foot to the front and the other to the back (FB). The transmissibility to the head differed among postures (t-test, p < 0.05) and was greatest with the FB posture and smallest with the BK posture. The transmissibility to the head decreased with increasing the frequency (t-test, p < 0.05) but the extent of the decrease depended on the adopted posture. This frequency-posture interaction effect on the transmissibility should be considered when designing a training program. The data will be useful for developing standards/protocols that govern the use of WBV machines as well as for building human body models that can predict potential risks arising from using WBV machines.  相似文献   
996.
Aim was to identify critical load (CL) in young and elderly apparently healthy male cohorts. To contrast the metabolic, cardiovascular and perceptual responses on CL according to age. We evaluated 12 young (23 ± 3 years) and 10 elderly (70 ± 2 years) apparently healthy active males, who underwent: (1) 1 repetition maximum (1RM) test on a 45° Leg Press; (2) on different days, three high-intensity resistance exercise constant load tests (60%, 75% and 90% 1RM) until fatigue (Tlim). Absolute values of both the CL asymptote and curvature constant (kg) were significantly lower in elderly subjects (P < 0.05). In contrast, elderly subjects demonstrated a significantly higher number of repetitions at CL when compared with young subjects (P < 0.05). As expected, oxygen uptake (VO2) and heart rate (HR) during maximal aerobic exercise testing were significantly reduced in older subjects. However, percent-predicted aerobic capacity were higher in older subjects (P < 0.05). In addition, blood lactate ([La?]) corrected to Tlim and rating of perceived exertion values were greater in younger subjects at all intensities (P < 0.05). These findings, despite reduced force production in older subjects, endurance-related parameters are well preserved according to age-adjusted percent-predicted values in apparently healthy males.  相似文献   
997.
ABSTRACT

Meta-analytic evidence supports that exercise has benefits for short-term memory (STM) and long-term memory (LTM). However, only three studies with children have tested the differential effects of exercise on STM and LTM. The purpose of this study was to examine the effects of an aerobic fitness test on STM and LTM and to consider the moderating effects of grade level. Children (7–13 years of age) were randomly assigned to either perform an aerobic fitness test before (exercise prior) or after (exercise post) performing the Rey Auditory Verbal Learning Test (RAVLT) to assess memory. Memory was tested again after approximately 24 hours. There were significant differences in memory performance as a function of grade with 4th and 6th graders consistently outperforming 2nd graders. For learning, Day 1 Retention, 24-hr recall, and Day 2 Retention, the exercise prior group performed better than the exercise post group. It is concluded that an aerobic fitness test performed prior to a declarative memory test benefits LTM as compared to when the aerobic fitness test is performed after the memory test.  相似文献   
998.
运动作为防治疾病的一味"药",正迅速被越来越多的医生所认可,并走进了大众的日常生活。运动既然是"药",就不该是"多多益善",而应该是"量体裁衣"、个性化定制,也因此需要处方。文章旨在回顾运动处方过去和现在的发展与对未来发展需求的猜测,对这个方兴未艾的领域增进了解,并进行系统介绍。追溯运动处方的研究和发展历史,大致可以分为4个时期3个阶段,从认识到运动对健康的重要性到运动成为防病治病的良药以及运动处方的发展走过了近70年的历程。国外大量科学的研究(尤其是追踪研究)和数据是支持运动处方不断前进的基石。从运动处方科学发展中所学到的智慧将会对中国传统运动处方的建设、中国大众的健康促进作出积极贡献。  相似文献   
999.
Purpose: To determine if: (i) mean power output and enjoyment of high-intensity interval training (HIIT) are enhanced by virtual-reality (VR)-exergaming (track mode) compared to standard ergometry (blank mode), (ii) if mean power output of HIIT can be increased by allowing participants to race against their own performance (ghost mode) or by increasing the resistance (hard mode), without compromising exercise enjoyment.

Methods: Sixteen participants (8 males, 8 females, VO2max: 41.2?±?10.8 ml?1·kg?1·min?1) completed four VR-HIIT conditions in a partially-randomised cross-over study; (1a) blank, (1b) track, (2a) ghost, and (2b) hard. VR-HIIT sessions consisted of eight 60 s high-intensity intervals at a resistance equivalent to 70% (77% for hard) maximum power output (PMAX), interspersed by 60 s recovery intervals at 12.5% PMAX, at a self-selected cadence. Expired gases were collected and VO2 measured continuously. Post-exercise questionnaires were administered to identify differences in indices related to intrinsic motivation, subjective vitality, and future exercise intentions.

Results: Enjoyment was higher for track vs. blank (difference: 0.9; 95% CI: 0.6, 1.3) with no other differences between conditions. There was no difference in mean power output for track vs. blank, however it was higher for track vs. ghost (difference: 5 Watts; CI: 3, 7), and hard vs. ghost (difference: 19 Watts; 95% CI: 15, 23).

Conclusions: These findings demonstrate that VR-exergaming is an effective intervention to increase enjoyment during a single bout of HIIT in untrained individuals. The presence of a ghost may be an effective method to increase exercise intensity of VR-HIIT.  相似文献   
1000.
目的观察12周惯性哑铃练习对轻度认知损害(MCI)老年人认知功能、身体活动能力、生活质量和睡眠质量的影响,并探讨认知改善与其他功能改变之间的关系。方法将45名MCI老年人随机分为干预组(n=22)和对照组(n=23)。干预组受试者进行惯性哑铃练习(3次/周,60 min/次,持续12周),对照组不进行运动干预。结果 12周后,干预组受试者阿尔茨海默病评定量表-认知部分(ADAS-Cog)总分/指令得分、蒙特利尔认知评估量表(MoCA)评分、起立行走计时(TUG)和SF-36健康调查问卷(SF-36)心理总得分均显著改善(均P<0.05)。与对照组相比,干预组受试者ADAS-Cog总分/单词回忆得分/注意力得分、简明精神量表(MMSE)评分、TUG和匹兹堡睡眠指数(PSQI)的改善程度均具有显著差异(P<0.05或P=0.05)。偏相关分析结果显示,SF-36心理总得分改变(r=-0.712)、PSQI改变(r=-0.380)与认知改善程度均呈显著负相关。结论 12周惯性哑铃练习可显著提高MCI老年人的认知功能,并对其移动能力、生活质量和睡眠质量具有积极影响,且心理和睡眠改变程度可能影响认知功能的改善效果。  相似文献   
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