低氧运动与骨骼肌血管内皮细胞生长因子     

王维群  姜文凯 《武汉体育学院学报》2007,41(2):52-57

低氧运动诱导的骨骼肌血管内皮细胞生长因子(VEGF)蛋白和基因表达,及毛细血管新生反应都属于速发效应。慢性低氧下调了静息时VEGF及其受体的转录,其能否诱导毛细血管新生的研究结果并不一致。低氧训练可使骨骼肌毛细血管增生,长期低氧训练对安静时骨骼肌VEGFmRNA水平影响不大。慢性低氧和低氧训练均可抑制运动对VEGFmRNA上调的表达效应,对此负反馈现象的时间规律和机制有待进一步研究。  相似文献   

间歇性低氧暴露适应过程中运动对人体甲襞微循环影响的实验研究     

谌晓安  田野  胡扬  王琳  陈啸科  孔兆伟 《北京体育大学学报》2004,27(3):333-335

研究目的:观察间歇性低氧暴露适应过程中,人体甲襞微循环的时序性变化及探讨可能机制.研究方法:7名足球专业学生,每天在低氧室(O2%:15.4%,CO2%〈5 000 ppm,温度23±3℃,湿度63±5%)内休息10 h,每周7 d,共4周.分别测试常氧常压、急性低氧暴露、低氧2周、4周后安静时和定量运动负荷后甲襞微循环的变化.结果表明:急性低氧暴露后,甲襞微环出现明显的代偿性变化;从甲襞微循环流态积分、总积分时序性变化的角度来看,间歇性低氧暴露4周的效果要优于间歇性低氧暴露2周.  相似文献   

低氧力竭运动及恢复期间大鼠骨骼肌肌原纤维ATPase活性的动态变化研究   总被引：3，自引：0，他引：3  

潘同斌  毛杉杉  王瑞元  袁建琴 《成都体育学院学报》2004,30(5):77-80

研究低氧力竭运动及恢复期间大鼠骨骼肌肌原纤维ATPase活性的动态变化.方法:取健康SD雌性大鼠152只,随机分成4组:常氧对照组(C)、常氧力竭组(OE)、低氧对照组(HC)、低氧力竭组(HE).其中HC、HE两低氧组在模拟4000米高原的低氧舱(氧浓度12.7%)进行低氧暴露及力竭后的低氧恢复;3天后OE、HE两个运动组均在常氧下进行一次力竭性跑台下坡运动.各组均于力竭后迅速选取股四头肌样本测定肌原纤维ATPase活性.结果:与C组相比,HC组在低氧数天后,股四头肌肌原纤维ATPase活性明显升高(P＜0.01),OE组力竭后24h才出现升高;而HE组则变化不显著,说明单纯低氧或常氧运动可引起肌原纤维ATPase活性升高,但两种因素并不是简单叠加,力竭后低氧恢复对肌纤维收缩活性不利.  相似文献   

传统高原训练、HiLo训练及间歇性低氧训练之理论比较刍议     

魏高峡  李佑发 《军事体育进修学院学报》2004,23(4):56-58

回顾了高原训练现状，对传统高原训练、HiLo训练及间歇性低氧训练进行了训练方式、训练负荷和生理学基础的理论比较。通过比较发现，间歇性低氧训练和HiLo训练是一种优于传统高原训练的训练方法。最后指出了今后的研究方向。  相似文献   

Hepcidin：低氧训练对机体铁代谢影响的关键调节因子     

杨杰  ;李海洲 《廊坊师范学院学报(自然科学版)》2014,(3):87-90

机体稳定的铁状态是维持生命活动的基本要素.诸多因素影响机体铁代谢,包括：饮食、低氧、运动等,其中低氧对机体铁代谢的影响备受关注.在机体铁代谢这个严密的调节系统中,关键调节因子Hepcidin在低氧影响机体铁稳态中起到了桥梁作用.低氧状态下Hepcidin调节铁代谢的分子机制成为近年来研究的热点.研究发现,低氧诱导因子（hypoxia inducible factor,HIF）/低氧反应元件（hypoxia response element,HRE）系统发挥着重要的作用,同时发现肥胖引起的局部低氧会导致铁代谢的紊乱,与低氧引发的炎症导致Hepcidin水平异常有关.另外发现低氧训练引起机体内氧浓度的变化会通过Hepcidin引起机体铁代谢适应性交化.  相似文献   

模拟高住低练对女子足球运动员运动能力影响的研究     

潘华山 《军事体育进修学院学报》2007,26(3):61-64

模拟高原训练方法之一的低氧屋有其独特的运动训练功能,通过观察用低氧屋间歇性常压低氧居住对女子足球运动员的运动能力的影响,发现：长期间歇性低氧居住可以提高女子足球运动员的运动能力,从一定程度来讲是低氧居住刺激RBC、Hb产生,血液携氧能力增加,最大摄氧量提高所致。  相似文献   

Intermittent hypoxia does not affect endurance performance at moderate altitude in well-trained athletes     

Martin Faulhaber  Hannes Gatterer  Thomas Haider  Carson Patterson  Martin Burtscher 《Journal of sports sciences》2013,31(5):513-519

Abstract

In this study, we examined the effects of a pre-acclimatization programme on endurance performance at moderate altitude using a resting intermittent hypoxia protocol. The time-trial performance of 11 cyclists was determined at low altitude (600 m). Athletes were randomly assigned in a double-blind fashion to the hypoxia or the control group. The pre-acclimatization programme consisted of seven sessions each lasting 1 h in normobaric hypoxia (inspired fraction of oxygen of 12.5%, equivalent to approximately 4500 m) for the hypoxia group (n = 6) and in normoxia (inspired fraction of oxygen of 20.9%) for the control group (n = 5). The time-trials were repeated at moderate altitude (1970 m). Mean power output during the time-trial at moderate altitude was decreased in the hypoxia group (?0.26 ± 0.11 W · kg^?1) and in the control group (?0.13 ± 0.04 W · kg^?1) compared with at low altitude but did not differ between groups (P = 0.13). Our results suggest that the applied protocol of intermittent hypoxia had no positive effect on endurance performance at moderate altitude. Whether different intermittent hypoxia protocols are advantageous remains to be determined.  相似文献   

Changes in running endurance performance following intermittent altitude exposure simulated with tents     

《European Journal of Sport Science》2013,13(1):15-24

Abstract

The effect of intermittent hypoxia on sea-level endurance performance was assessed by using hypoxic tents to simulate the live high-train low approach to altitude training. Eleven male sub-elite competitive runners and triathletes participated in a crossover study of usual training (control) and usual training with altitude exposure (altitude). Altitude treatment consisted of 25±3?d (mean±SD) of sleeping in tents for 8.1±0.6?h.d^?1, progressing from a simulated altitude of 2500?m to 3500?m above sea level. Washout period between control and altitude treatments was 4?wk. Three treadmill runs to exhaustion lasting ～2, ～4 and ～8?min were completed 7 and 12?d after control and altitude treatments. Times for standard competition distances (800, 1500 and 3000?m), were predicted using a log-log model, improved by 1.0% (90% confidence limits, ±1.3%), 1.4% (±1.2%) and 1.9% (±1.5%), respectively. Improvements were greater in the six athletes with an I allele for angiotensin converting enzyme (ACE): 2.3% (±1.5%), 2.2% (±1.5%), and 2.1%, (±2.1%), respectively. Effects of simulated altitude on hemoglobin concentration were unclear. Altitude exposure simulated with hypoxic tents is likely to enhance performance substantially in middle-distance endurance running events, especially for individuals with an I allele of the ACE gene.  相似文献   

Effect of environmental feedbacks on pacing strategy and affective load during a self-paced 30 min cycling time trial     

Alexandre Abel  Bertrand Baron  Frédéric Grappe  Marc Francaux 《Journal of sports sciences》2019,37(3):291-297

The purpose of this study was to analyze the pacing strategy and its affective consequences during self-paced cycling time trials (TT) performed at different severity of hypoxia. Eight competitive cyclists performed five 30 min self-paced TTs at their best performance in the following conditions: 1) normobaric normoxia (NN_SL); 2) normobaric hypoxia under two simulated altitudes: 2000 m (NH₂₀₀₀) and 3500 m (NH₃₅₀₀) and 3) normobaric hypoxia but the cyclists were deceived and thought to be at sea level for 2000 m (DecNH₂₀₀₀) and 3500 m (DecNH₃₅₀₀). Power Output (PO), oxygen uptake (VO₂), and blood lactate concentration ([La]) were recorded to assess exercise intensity and physiological adaptations. The rate of perceived exertion (RPE) and pleasure were measured with a CR10 Borg scale to evaluate the affective load (AL). PO and VO₂ decreased with the severity of hypoxia but no significantly difference on performance was measured between deceived and real conditions, except for pacing strategy. The started intensity depends on the exercise expectations, but PO was rapidly adjusted with the physiological constraints and the rate of increase of RPE. Finally, AL did not reach maximal values so that the athletes sustained a physiological and emotional reserve to perform a final spurt.  相似文献   

短期低氧抗阻训练对男子体操运动员有氧、无氧运动能力的影响*     

贾〓钧  王晨宇 《广州体育学院学报》2020,(2):92-96

目的：探讨低氧环境下进行4周循环抗阻训练（CRT）对男子体操运动员有氧、无氧运动能力的影响，为科学化训练提供理论支持。方法：16名男子体操运动员随机分为低氧训练（hypoxia training，HT）组和常氧训练（normoxia training，NT）组，每组n＝8。NT组和HT组受试者分别于常氧和低氧（模拟3000 m高度）环境下进行4周CRT。实验前后利用递增负荷力竭实验（最大摄氧量、最大有氧功率等）测定有氧运动能力，利用运动场测试（300 m全力冲刺记时跑和300 m反复间歇跑测试）与实验室测试（股四头肌最大随意收缩、半蹲跳、下蹲跳和30 s Wingate实验）测定无氧运动能力，静脉取血测定血液学参数。结果：组内与实验前比较，实验后HT组300 m反复间歇跑完成次数、峰值LA含量（LApeak）、股四头肌最大随意收缩（MVC）、半蹲跳（SJ）、下蹲跳（CMJ）、峰值功率（PP）和平均功率（MP）显著性升高（P<0.05），NT组LApeak、MVC、SJ、CMJ、PP和MP升高（P<0.05）；组间与NT组比较，实验后HT组300 m反复间歇跑完成次数、LApeak、MVC、SJ、CMJ、PP和MP升高（P<0.05）。有氧运动能力参数和血液学参数在两组实验前后均无显著性变化（P>0.05）。CRT过程中的平均心率（HRmean）在HT组高于NT组（P<0.05）。结论：低氧环境下进行CRT能够显著改善男子体操运动员无氧运动能力，其机制可能与耐乳酸能力增强有关，但对有氧运动能力无显著影响。  相似文献