视觉加工对英语母语者汉语声调产出的影响     

贾琳  王建勤 《暨南大学华文学院学报》2013,(4):30-34

本文考察了视觉加工对英语母语者汉语声调产出的影响,并引入多模态学习理论通过不同的实验任务考察了视觉加工影响学习者声调产出的内在机制,研究表明：（1）在延时测试中,对零起点汉语学习者来说。三周的视听知觉训练没有显著改善学习者的声调产出;（2）对于低水平汉语学习者来说．即时呈现教师的手势可以引导学习者发音器官的运动,可用于课堂上的即时纠音。对于高水平学习者来说,由于四个声调的发音模式已经建立并固定下来,不易受教师手势的干扰。  相似文献   

基于大学生视角的经济管理实验教学效果分析     

王若  赵学凯 《实验技术与管理》2012,29(6):150-154

从学生的视角看经济管理实验教学的实际效果,及了解学生在参加这类课程的学习与训练后的体会和收获。课题组有针对性地设计了调查问卷,并在此基础上对学生的反馈信息进行统计分析。最后,根据统计信息发现问题并提出相应的改进建议供有关教学部门参考。  相似文献   

雍正朝河南省耗羡归公政策研究     

王学深  房蓉 《南阳师范学院学报》2012,11(4):16-20

雍正帝自执政之始就推动了一系列的改革,耗羡归公是其中的一项政策,此政策对于弥补各地亏空,充实国库,减轻人民负担等起着促进作用。本文以河南省推行耗羡归公为例,通过考证河南省耗羡归公的起始日期及耗羡银用途,以窥见耗羡归功政策的实施。  相似文献   

新形势下雷锋精神的弘扬之道     

蒋晓侠 《安徽师范大学学报(人文社会科学版)》2012,(2):172-176,200

市场经济背景下,一些人对于弘扬雷锋精神,存在一些误解;网调结果不理想,见危不助等现象突显当前雷锋精神缺失的现状。不完善的市场经济强化了人们的趋利意识,造成普遍信任的缺失;转型期社会生活的无根性强化了人的自保意识;外来文化思想颠覆"重义轻利"的传统观念,对弘扬雷锋精神造成巨大冲击;学雷锋活动往往流于形式、实效性低。新形势下,要构建社会主义核心价值观和社会信用体系,为学雷锋活动提供理论支撑和制度保障;解放思想、转变观念,扩大学雷锋活动的覆盖面;多措并举,提高雷锋精神宣传教育工作的实效性。  相似文献   

中英文交际用语的差别与应对策略   总被引：1，自引：0，他引：1  

熊英 《湖北第二师范学院学报》2012,(5):33-35

交际用语是对外交往中必不可少的语言,然而由于历史文化、风俗习惯等原因,不同文化间的交际用语存在着差异。本文通过列举具体事例,结合自身在国外学习的经历,阐述中英文常用交际用语差异,分析背后反映的中西方文化差异,并逐条对英语学习者提出应对建议。笔者认为,只有打下扎实的中外文语言功底,培养跨文化意识,才能更好地开展对外交流。  相似文献   

高校书法公修课教学评价研究     

戚荣金 《四川教育学院学报》2010,26(5):18-20

高校书法公修课的教学目标遵循以学生发展为本的思想,强调大学生综合素质、人文素养和终身学习能力的形成。建立完善、科学的教学评价体系是实现这一目标的关键。评价应保证书法教学目标的顺利实现,应对书法教学内容进行准确定位,应促进书法教学和教师的发展,应建立多元化的书法教学评价体系。  相似文献   

Heat shock protein 90 protects rat mesenchymal stem cells against hypoxia and serum deprivation-induced apoptosis via the PI3K/Akt and ERK1/2 pathways     

Feng Gao  Xin-yang Hu  Xiao-jie Xie  Qi-yuan Xu  Ya-ping Wang  Xian-bao Liu  Mei-xiang Xiang  Yong Sun  Jian-an Wang 《Journal of Zhejiang University. Science. B》2010,11(8):608-617

Mesenchymal stem cell(MSC)transplantation has shown a therapeutic potential to repair the ischemic and infracted myocardium,but the effects are limited by the apoptosis and loss of donor cells in host cardiac microenvironment.The aim of this study is to explore the cytoprotection of heat shock protein 90(Hsp90)against hypoxia and serum deprivation-induced apoptosis and the possible mechanisms in rat MSCs.Cell viability was determined by3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT)assay.Apoptosis was assessed by Hoechst 33258nuclear staining and flow cytometric analysis with annexin V/PI staining.The gene expression of Toll-like receptor-4(TLR-4)and V-erb-b2 erythroblastic leukemia viral oncogene homolog 2(ErbB2)was detected by real-time polymerase chain reaction(PCR).The protein levels of cleaved caspase-3,Bcl-2,Bcl-xL,Bax,total-ERK,phospho-ERK,totaI-Akt,phospho-Akt,and Hsp90 were detected by Western blot.The production of nitric oxide was measured by spectrophotometric assay.Hsp90 improves MSC viability and protects MSCs against apoptosis induced by serum deprivation and hypoxia.The protective role of Hsp90 not only elevates Bcl-2/Bax and Bcl-xL/Bax expression and attenuates cleaved caspase-3 expression via down-regulating membrane TLR-4 and ErbB2 receptors and then activating their downstream PI3K/Akt and ERK1/2 pathways,but also enhances the paracrine effect of MSCs.These findings demonstrated a novel and effective treatment strategy against MSC apoptosis in cell transplantation.  相似文献   

Sevoflurane postconditioning reduces myocardial reperfusion injury in rat isolated hearts via activation of PI3K/Akt signaling and modulation of Bcl-2 family proteins     

Li-na Yu  Jing Yu  Feng-jiang Zhang  Mei-juan Yang  Ting-ting Ding  Jun-kuan Wang  Wei He  Tao Fang  Gang Chen  Min Yan 《Journal of Zhejiang University. Science. B》2010,11(9):661-672

Sevoflurane postconditioning reduces myocardial infarct size.The objective of this study was to examine the role of the phosphatidylinositol-3-kinase(PI3K)/Akt pathway in anesthetic postconditioning and to determine whether PI3K/Akt signaling modulates the expression of pro-and antiapoptotic proteins in sevoflurane postconditioning.Isolated and perfused rat hearts were prepared first,and then randomly assigned to the following groups:Sham-operation(Sham),ischemia/reperfusion(Con),sevoflurane postconditioning(SPC),Sham plus 100 nmol/L wortmannin(Sham+Wort),Con+Wort,SPC+Wort,and Con+dimethylsulphoxide(DMSO).Sevoflurane postconditioning was induced by administration of sevoflurane(2.5%,v/v) for 10 min from the onset of reperfusion.Left ventricular developed pressure(LVDP),left ventricular end-diastolic pressure(LVEDP),maximum increase in rate of LVDP(+dP/dt),maximum decrease in rate of LVDP(?dP/dt),heart rate(HR),and coronary flow(CF) were measured at baseline,R30 min(30 min of reperfusion),R60 min,R90 min,and R120 min.Creatine kinase(CK) and lactate dehydrogenase(LDH) were measured after 5 min and 10 min reperfusion.Infarct size was determined by triphenyltetrazolium chloride staining at the end of reperfusion.Total Akt and phosphorylated Akt(phospho-Akt),Bax,Bcl-2,Bad,and phospho-Bad were determined by Western blot analysis.Analysis of variance(ANOVA) and Student-Newman-Keuls' test were used to investigate the significance of differences between groups.The LVDP,±dP/dt,and CF were higher and LVEDP was lower in the SPC group than in the Con group at all points of reperfusion(P0.05).The SPC group had significantly reduced CK and LDH release and decreased infarct size compared with the Con group [(22.9±8)% vs.(42.4±9.4)%,respectively;P0.05].The SPC group also had increased the expression of phospho-Akt,Bcl-2,and phospho-Bad,and decreased the expression of Bax.Wortmannin abolished the cardioprotection of sevoflurane postconditioning.Sevoflurane postconditioning may protect the isolated rat heart.Activation of PI3K and modulation of the expression of pro-and antiapoptotic proteins may play an important role in sevoflurane-induced myocardial protection.  相似文献   

东日本大地震中的地质信息服务经验与教训   总被引：1，自引：0，他引：1  

朱卫红  颜世强 《情报杂志》2012,31(4):170-174

回顾了3 ·11东日本大地震的发生和受灾状况,分析了地质信息服务在本次地震中的应用效果,并从多个角度对日本的地质信息服务技术、内容及体制进行反思,总结了其中的成功经验和失败教训,揭示了提高信息服务的可靠性和服务水平所需要解决的重大课题.最后结合我国的实际情况,明确了我们在地质信息服务管理体制、技术和观念上的发展方向,并提出政策性建议.  相似文献   

高等院校小学教育专业课程方案探析   总被引：4，自引：0，他引：4  

邓艳红  俞劼  陈惠国 《课程.教材.教法》2009,(2)

在本科层次小学教师专业兴办十年之际,通过对全国23所院校小学教育专业本科层次课程方案的分析以及与部分院校的访谈发现,当前小学教育专业在培养目标、培养规格、课程设置、课程实施与评价等方面存在诸多值得反思的问题。应确立区分于专科及研究生培养层次的、将小学教师教育与基础教育质量提升相联系的、适切性和可操作性强的培养目标和规格,进一步规范课程设置,积极开发新型教师教育综合课程,使小学教师教育成为新课改理念的示范。  相似文献