On the Uncertainty of“True-being”: from“Chuang Zhou’s Dreaming of Becoming a Butterfly”     

郭婷 《海外英语》2021,(2)

This paper tries to make a philosophical speculation towards the“uncertainty”of“true-being”from the following three aspects:first,Chuang Tzu’s philosophy on skepticism and the uniformity of all things reflected on“Chuang Zhou’s Dreaming of Becoming A Butterfly”;second,Descartes’skepticism on the existence of true being;last,the ongoing exploring of the true being.Through the reflections on different philosophers’speculations towards the same proposition,the belt between Chinese and western philosophy is built,providing a broaden horizon and thinking mode towards life.  相似文献   

Effect of dietary nutrition on tail fat deposition and evaluation of tail-related genes in fat-tailed sheep     

《Electronic Journal of Biotechnology》2020

BackgroundThe effects of dietary nutrition on tail fat deposition and the correlation between production performance and the Hh signaling pathway and OXCT1 were investigated in fat-tailed sheep. Tan sheep were fed different nutritional diets and the variances in tail length, width, thickness and tail weight as well as the mRNA expression of fat-related genes (C/EBPα, FAS, LPL, and HSL) were determined in the tail fat of sheep at three different growth stages based on their body weight. Furthermore, the correlations between tail phenotypes and the Hedgehog (Hh) signaling pathway components (IHH, PTCH1, SMO, and GLI1) and OXCT1 were investigated.ResultsC/EBPα, FAS, LPL, and HSL were expressed with differences in tail fat of sheep fed different nutritional diets at three different growth stages. The results of the two-way ANOVA showed the significant effect of nutrition, stage, and interaction on gene expression, except the between C/EBPα and growth stage. C/EBPα, FAS, and LPL were considerably correlated with the tail phenotypes. Furthermore, the results of the correlation analysis demonstrated a close relationship between the tail phenotypes and Hh signaling pathway and OXCT1.ConclusionsThe present study demonstrated the gene-level role of dietary nutrition in promoting tail fat deposition and related tail fat-related genes. It provides a molecular basis by which nutritional balance and tail fat formation can be investigated and additional genes can be identified. The findings of the present study may help improve the production efficiency of fat-tailed sheep and identify crucial genes associated with tail fat deposition.How to cite: Zeng J, Zhou S, Yang Y, et al. Effect of dietary nutrition on tail fat deposition and evaluation of tail-related genes in fat-tailed sheep. Electron J Biotechnol 2020;46. https://doi.org/10.1016/j.ejbt.2020.05.004.  相似文献   

图书流通数据分析的H类指数遴选及应用——以西北农林科技大学图书馆为例     

净玲娣  王立宏  王芹  李雅 《图书情报工作》2020,64(9):65-72

[目的/意义] 优化藏书采访工作和流通管理，实现对藏书采访、藏书总量和结构等状况适时监测、评估、调控等的标准化管理。[方法/过程] 通过对H类指数中的H指数、A指数和G指数相关性、变异性和适应性分析，遴选适用于图书流通数据分析的A指数，并根据帕累托定律采用A指数对西北农林科技大学图书馆2014-2018年的前20%的图书流通数据分别进行统计分析。[结果/结论] 研究结果表明：平均A指数对中图法一级类目与读者性别、读者专业、读者年级以及图书出版社、图书出版年、单位等数据统计分析具有较理想的表现，能够更全面、准确地遴选核心读者群、核心出版者和核心出版年；同时发现，布拉德福定律不仅能够应用于期刊管理，而且能够应用于藏书管理。本文研究能够为探索H类指数分析高校图书馆藏书流通数据提供参考依据。  相似文献   

项目教学法在单片机课程教学中的实践   总被引：1，自引：0，他引：1  

郭文川 《中国现代教育装备》2011,(1):112-114

单片机原理与接口技术是一门理论性、实践性和综合性很强的课程。在分析传统的单片机课程教学存在问题的基础上,介绍了项目教学法的思想。从而详细阐述了笔者如何在单片机课程的理论和实践教学中实施项目教学法。  相似文献   

基于过程管理的高职院校学生顶岗实习档案管理研究     

王亚丽 《杨凌职业技术学院学报》2021,(1)

文章从创建高职院校学生顶岗实习档案的必要性着手,对高职院校学生顶岗实习档案管理的现状进行了分析,并针对目前顶岗实习档案管理中存在的问题提出了几点建议。  相似文献   

重建土壤水库是黄土高原治本之道   总被引：12，自引：0，他引：12       下载免费PDF全文

朱显谟 《中国科学院院刊》2006,21(4):320-324

基于黄土高原严重的生态环境问题,在分析黄土高原成因机理及结构特点基础上,探讨了黄土高原“土壤水库”的功能,研究了地表水库、土壤水库、地下水库三库协防在治理黄土高原环境方面的重要作用。结果表明,应将重建土壤水库,实现三库协防,作为构建和谐黄土高原,再现秀美山川的理论依据和指导方针,而地表径流调控与水土资源持续利用技术研究,可为黄土高原国土整治“28字方略”理论实现提供重要的技术支撑。  相似文献   

变异系数加权的组合赋权模型及科技评价实证          下载免费PDF全文

石宝峰  程砚秋  王静 《科研管理》2016,37(5):122-131

通过R聚类剔除反映信息重复的指标,利用因子分析遴选对科技评价影响较大的指标,构建了能够反映科学发展观内涵的科技评价指标体系。在此基础上,利用变异系数对主观G1权重、客观余弦夹角权重进行组合加权,建立了基于变异系数加权的组合赋权模型,并对中国14个典型的省份科技评价数据进行了实证。创新与特色:一是通过变异系数对主观G1权重、客观余弦夹角权重进行加权,构建了变异系数加权后组合权重最大的目标函数,进而确定了主、客观权重的组合系数θ_1、θ_2,反映了组合赋权中主、客观权重分布变异性越大、权重越大的赋权思路。弥补了现有组合赋权中主、客观权系数相等,无法有效反映专家知识经验和客观数据差异的不足。二是实证研究表明:科技投入不足是制约江西、广西两省科技发展较差的主要因素;科技对经济与社会的影响偏弱是制约四川省科技发展的关键因素;科技产出不足是制约黑龙江、山东、河南三省科技发展的瓶颈因素。  相似文献   

CRISPR/Cas9-mediated MSTN gene editing induced mitochondrial alterations in C2C12 myoblast cells     

《Electronic Journal of Biotechnology》2019

BackgroundMyostatin (MSTN) negatively regulates muscle mass and is a potent regulator of energy metabolism. However, MSTN knockout have affect mitochondrial function. This research assessed the mitochondrial energy metabolism of Mstn −/+ KO cells, and wondered whether the mitochondria biogenesis are affected.ResultsIn this study, we successfully achieved Mstn knockout in skeletal muscle C2C12 cells using a CRISPR/Cas9 system and measured proliferation and differentiation using the Cell-Counting Kit-8 assay and qPCR, respectively. We found that MSTN dysfunction could promote proliferation and differentiation compared with the behaviour of wild-type cells. Moreover, Mstn KO induced an increase in KIF5B expression. The mitochondrial content was significantly increased in Mstn KO C2C12 cells, apparently associated with the increases in PGC-1α, Cox1, Cox2, ND1 and ND2 expression. However, no differences were observed in glucose consumption and lactate production. Interestingly, Mstn KO C2C12 cells showed an increase in IL6 and a decrease in TNF-1α levels.ConclusionThese findings indicate that MSTN regulates mitochondrial biogenesis and metabolism. This gene-editing cells provided favourable evidence for animal breeding and metabolic diseases.How to cite: Wang L, Ding Q, Ma S, et al. CRISPR/Cas9-mediated MSTN gene editing Induced Mitochondrial Alterations in C2C12 myoblast Cells. Electron J Biotechnol 2019;40. https://doi.org/10.1016/j.ejbt.2019.03.009  相似文献   

农业高校科技成果产业化模式与发展对策初探   总被引：1，自引：0，他引：1  

张晓妮  梁宗祥  张海成  孙楠 《技术与创新管理》2006,27(6):56-58

系统总结了我国农业高校科技成果-高新技术产业化发展过程中初步形成的七种运行模式,并分析各种模式的特点和适用范围；通过研究、评价农业高校科技成果产业化发展中面临的主要问题,提出了高校科技管理、科技组织创新、科技中介市场建设、科技风险投资、国际科技合作等方面的对策措施。  相似文献   

失地农民职业技能培训现状分析及对策研究——基于陕西杨凌示范区的调查     

赵艳霞  张红 《职业技术教育》2011,32(16)

通过职业技能培训提高失地农民的技能水平,是增强失地农民可持续发展能力,解决失地农民问题的关键.调查显示,失地农民职业技能培训现状还不理想,存在诸如内容设置不合理、培训力度不够等问题.针对这些问题,我国政府应进一步发挥主导作用,构建具有失地农民特色的职业技能培训内容体系,建立失地农民职业技能培训效果评价机制和外部支持体系.  相似文献