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While there are various approaches to gerontological and geriatrics (and social sciences) education globally, a component commonly included in undergraduate education is a final thesis project. In Turkey, the Department of Gerontology at Akdeniz University has undertaken a unique approach to thesis development that values and draws on accessing the greater expertise and knowledge of faculty and students through joint collaborations. We offer an overview of the eleven stages of a collective thesis development approach as an alternative to the conventional way of conducting oversight of undergraduate thesis projects. With four years of experience, observed benefits of a collective thesis development approach for students include the opportunity to draw on the comradery, insights, and experience of a plurality of educators and aspiring students while developing, executing, and documenting a thesis project. Benefits to advisors/educators include profiting from the strengths in other advisors and wider exposure to current research, findings, and methodological approaches. So while there may be multifold variations in curriculum content and educational approaches, it is of great importance that educators create “spaces” that give value to and foster the pursuit of collective wisdom through joint collaborations. (188 words)  相似文献   
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Hypertension, a well known risk factor for various cardiovascular, peripheral vascular and renal events is an important public health challenge. Renin angiotensin system (RAS) being the most vital pathogenic mechanism of hypertension is mediated by a key component; the angiotensin converting enzyme (ACE). The present study was aimed to know the relationship of ACE gene polymorphism and the possible risk of development of hypertension in south Indian population. The study included 101 clinically diagnosed hypertensive patients without any associated disease condition and 81 age and sex matched apparently healthy controls. Genotyping was performed using a polymerase chain reaction, (PCR) amplification of the intron 16 fragment harboring the 287 bp Alu repeat sequence. Three possible genotypes D/D, I/I homozygous and I/D heterozygous were analyzed where the D/D genotypes corresponds to higher ACE levels (D-Deletion, I-Insertion). The PCR products were separated on 2 % agarose gel. Statistical analysis was performed using SPSS.15 software program. We found a significance in frequency of D/D genotype in the hypertensive patients compared to the control group (p = 0.0005, odd’s ratio = 4.157). This suggested that ACE (D/D) genotypes are more prone for the development of hypertension. This is relatively a pilot study; but nevertheless may assist in identifying the pathophysiological cause of hypertension.  相似文献   
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Pretreatment of an ethanolic extract of leaf ofPiper betle linn at a dose of 200mg/kg body weight, orally administered to rats for ten consecutive days, was found to possess a significant protective action against gastric lesions induced by indomethacin. The extract pretreatment resulted in significant increase in superoxide dismutase (SOD) and catalase (CAT) activity, increase in mucus, hexosamine and total thiol group content, but marked reduction in oxidatively damaged protein and peroxidised lipid levels as compared to untreated ulcerated control. The extract was also found to possess both superoxide and hydroxyl free radical scavenging action. The present observations establish the efficacy of the extract in prevention of experimentally induced peptic ulcer by indomethacin and antioxidant property appears to be predominantly responsible for such cytoprotective activity in the experimental model.  相似文献   
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Given the paucity of studies conducted to know the effect of suddenness and earlier onset of endocrinological changes associated with hysterectomy, on the serum and urinary levels of calcium, magnesium and phosphate the present study was conducted to compare the levels of calcium, magnesium and phosphate in serum and urine of hysterectomised and natural menopausal south Indian women. This is a cross-sectional observational study. The study included three groups of 30 healthy premenopausal, 30 early surgical menopausal and 30 natural post menopausal women. Women suffering from any endocrine disease were excluded. Analysis was performed in serum and urine sample. The levels of calcium, magnesium and phosphate in serum and calcium/creatinine, magnesium/creatinine and phosphate/creatinine ratio were estimated in urine by spectrophotometric method. Hysterectomised women (serum calcium: 8.7 ± 0.09 mg/dl; urine calcium/creatinine: 0.16 ± 0.02) have significantly low serum calcium (p < 0.001) and high urinary calcium/creatinine (p = 0.002) ratio and post menopausal women (serum magnesium: 2.1 ± 0.03; serum phosphate: 4.4 ± 0.16; urinary calcium/creatinine: 0.17 ± 0.02; urinary magnesium/creatinine: 0.09 ± 0.01) have significantly high serum magnesium (p = 0.016), serum phosphate (p = 0.043) and high urinary calcium/creatinine (p = 0.002), magnesium/creatinine ratio (p = 0.025) compared to healthy pre menopausal women. Post menopausal women (serum calcium: 9.1 ± 0.08) have significantly high serum calcium and phosphate compared to hysterectomised women (serum phosphate: 3.93 ± 0.11). Hysterectomised women have significantly low serum calcium, oestrogen and high urinary calcium/creatinine ratio compared to healthy premenopausal women and low serum calcium and low serum phosphate compared to natural postmenopausal women. Natural postmenopausal women had low serum oestrogen and high serum magnesium, serum phosphate, urinary calcium creatinine ratio and urinary magnesium creatinine ratio compared to healthy premenopausal women.  相似文献   
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Topological insulators are new class of materials which are characterized by a bulk band gap like ordinary band insulators but have protected conducting states on their edges or surfaces. These states emerge due to the combination of spin-orbit coupling and time reversal symmetry. Also, these states are insensitive to scattering by non-magnetic impurities. A two-dimensional topological insulator has one dimensional edge states in which the spin-momentum locking of the electrons give rise to quantum spin Hall effect. A threedimensional topological insulator supports novel spin-polarized 2D Dirac fermions on its surface. These topological insulator materials have been theoretically predicted and experimentally observed in a variety of 2D and 3D systems, including HgTe quantum wells, BiSb alloys, and Bi2Te3, Bi2Se3 crystals. Moreover, proximity induced superconductivity in these systems can lead to a state that supports zero energy Majorana fermions, and the phase is known as topological superconductors. In this article, the basic idea of topological insulators and topological superconductors are presented along with their experimental development.  相似文献   
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A comparison of the absorbance, enzyme/substrate concentration, reaction efficiency and sensitivity has been made for enzyme-based clinical chemistry assays, using a conventional colorimeter versus a strip-microwell reader, in order to establish the value of ultra-microchemical procedure, with reaction volume 87 μl (light path length=0.25 cm). By utilizing commercial kits available for the quantitation of serum glucose, cholesterol and triglycerides, it has been established that the micro method is highly cost effective (9–30 fold), reproducible and sensitive. Comparison of blood drawn by a finger prick (capillary) and venipuncture for normal and pathological specimens show reproducibility between different laboratory technologists and in reference with the values reported by an accredited reference laboratory. Since the micro method uses very little serum, it is most suitable for analyses of small smaples, from large population-based field trials. However, the assay range has to be titrated for each commercial kit to establish the enzyme/substrate equivalence.  相似文献   
9.
The article outlines the life and work of Maryam Mirzakhani — the first and the only female winner of the Fields Medal since its inception in 1936. Mirzakhani is an inspiration to young women around the world, to believe in their own abilities and pursue their academic dreams.  相似文献   
10.
INTRODUCTION The particle swarm optimization (PSO) method is a member of the broad category of swarm intelli- gence techniques for finding optimized solutions. The PSO algorithm is based on the social behavior of animals such as flocking of birds and schooling of fish, etc. PSO has its origin in simulation for visual- izing the synchronized choreography of bird flock by incorporating concepts such as nearest-neighbor ve- locity matching and acceleration by distance (Par- sopoulos and V…  相似文献   
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