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1.
Chai-Hong Yeong Mu-hua Cheng Kwan-Hoong Ng 《Journal of Zhejiang University. Science. B》2014,15(10):845-863
The potential use of radionuclides in therapy has been recognized for many decades. A number of radionuclides, such as iodine-131 (131I), phosphorous-32 (32P), strontium-90 (90Sr), and yttrium-90 (90Y), have been used successfully for the treatment of many benign and malignant disorders. Recently, the rapid growth of this branch of nuclear medicine has been stimulated by the introduction of a number of new radionuclides and radiopharmaceuticals for the treatment of metastatic bone pain and neuroendocrine and other malignant or non-malignant tumours. Today, the field of radionuclide therapy is enjoying an exciting phase and is poised for greater growth and development in the coming years. For example, in Asia, the high prevalence of thyroid and liver diseases has prompted many novel developments and clinical trials using targeted radionuclide therapy. This paper reviews the characteristics and clinical applications of the commonly available therapeutic radionuclides, as well as the problems and issues involved in translating novel radionuclides into clinical therapies. 相似文献
2.
放射性核素的临床应用及研究已历数十载,已有碘-131、磷-32、锶-90及钇-90等众多放射性核素被成功用于治疗良恶性疾病。随着新的放射性核素及药物不断应用于骨转移瘤疼痛治疗、神经内分泌肿瘤及其他良恶性肿瘤治疗,放射性核素治疗得到了快速发展。目前,放射性核素治疗已进入蓬勃发展期;在亚洲,由于甲状腺和肝脏肿瘤的高发病率,促进了放射性核素治疗及其靶向治疗研究的日益发展。随着放射性核素与其他药物的联合应用,放射性核素治疗肿瘤的临床价值必将显著提高。 相似文献
3.
The relationship between linguistic experience and phonemic representations in spelling was investigated in two groups of Mandarin–English bilingual children (aged 5–6 years) who spoke mostly Mandarin-L1 (n = 23) or mostly English-L1 (n = 27) at home. A 60-item cloze task including high- and low-frequency words with word-initial and word-final target phonemes that are either common to Mandarin and English (/f/ and /p/), or found only in English (/v/ and /b/), was developed and administered to both groups. With performance for a neutral control phoneme /m/ matched, spelling accuracy for the common phonemes was equivalent but the Mandarin-L1 children's performance for /v/ and /b/ was significantly poorer than that of their English-L1 classmates in low-frequency words. For both groups, performance on word-final targets was poorer for English-only phonemes than common phonemes. If early literacy development depends on stored phonological representations of the first language, these findings have implications for language minority communities. 相似文献
4.
Language Brokering and Depressive Symptoms in Mexican‐American Adolescents: Parent–Child Alienation and Resilience as Moderators 
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下载免费PDF全文 This study aimed to untangle the mixed effects of language brokering by examining a contextual factor (i.e., parent–child alienation) and a personal attribute (i.e., resilience) that may relate to adolescents’ feelings during translating (i.e., sense of burden and efficacy) and that may moderate the association between such feelings and adolescent depressive symptoms. Participants included 557 adolescent language brokers (Mage = 12.96) in Mexican‐American families. Results showed that adolescents with a strong sense of alienation from parents or low resilience (a) experienced more burden or less efficacy in translating and (b) were more susceptible to the detrimental effects of feeling a sense of burden and the beneficial effects of experiencing a sense of efficacy, as measured by depressive symptoms. 相似文献
5.
Parents' Perceived Discrimination and Adolescent Adjustment in Chinese American Families: Mediating Family Processes 下载免费PDF全文
下载免费PDF全文 Parental discriminatory experiences can have significant implications for adolescent adjustment. This study examined family processes linking parental perceived discrimination to adolescent depressive symptoms and delinquent behaviors by using the family stress model and incorporating family systems theory. Participants were 444 Chinese American adolescents (Mage.wave1 = 13.03) and their parents residing in Northern California. Testing of actor–partner interdependent models showed a significant indirect effect from earlier paternal (but not maternal) perceived discrimination to later adolescent adjustment through paternal depressive symptoms and maternal hostility toward adolescents. The results highlight the importance of including both parents and examining actor and partner effects to provide a more comprehensive understanding of how maternal and paternal perceived discrimination differentially and indirectly relate to adolescent adjustment. 相似文献
6.
Foong May Yeong 《高等教育研究与发展》2014,33(5):1078-1080
7.
Hye Yeong Kim 《Teaching in Higher Education》2013,18(3):281-292
This study explores the factors that cause international graduate students to struggle and these students' ways of dealing with such problems in light of sociocultural theory, which views learning as a social and cultural act. The findings show that graduate classes function as communities of practices in which classmates and professors mutually engage with each other, share a repertoire and engage in joint enterprises. The practices were not always transparent to international students, which became a source of difficulty and often led them to feel excluded. Peripheral participation comprised a significant part of some students' learning process and identity formation, but it allowed them to participate in course-related activities as fully as they felt comfortable doing. This study suggests a need for more sensitive and dialogical efforts by educators in higher education to provide better learning environments for international learners. 相似文献
8.
This study examined the importance of morphological awareness in Korean–English biliteracy acquisition. English is an opaque orthographic system, in which letters and sounds have indirect correspondences. Korean Hangul, on the other hand, is a transparent orthographic system where there are direct letter-sound correspondences. Sixty-five children from Grades 2 to 4 were tested on a set of comparable Korean and English tasks tapping into oral vocabulary, phonemic awareness, morphological awareness, real word reading, and passage reading comprehension. Results showed that morphological awareness explained a significant amount of variance in word reading and reading comprehension within both Korean Hangul and English, suggesting that morphological awareness is important not only in an opaque orthography but also in a transparent orthography. Furthermore, morphological awareness in one language uniquely predicted a significant amount of variance in reading real words in the other language, suggesting that morphological awareness facilitates word reading across different orthographies. 相似文献
9.
We report on knowledge about old age among social service providers from three service networks. Data are based on a survey of 245 respondents from Washington State's developmental disabilities, aging, and generic service networks. Palmore's Facts on Aging Quiz (FAQ; 1977, 1988) was used to measure the level of knowledge about old age. Key findings are as follows: (a) Overall, the respondents averaged 64% correct on the FAQ. (b) Developmental disabilities service providers scored lower than either aging service providers or generic service providers. (c) The content areas in which items were most often missed were the psychological aspects aging, the demographic trends of the aging population, and the socioeconomic status of the elderly. Implications of the results for training service providers are discussed. 相似文献
10.
Taekwondo's cultural identity is considered in the light of the controversy over its historical origins. After reviewing several existing theories, the meaning and development of taekwondo as a Korean martial art is explored. There are two conclusions: first, taekwondo is a fusion of several different sources; second, taekwondo is essentially a martial art that focuses on foot skills, and this distinguishes it from Japan's karate and China's wushu, which are primarily based on hand skills. The fact that all terms are rendered into pure Korean words shows the essence of Korean localization. Thus taekwondo incorporates a distinct identity as a Korean martial art. 相似文献