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In this article we derive the distribution, mean and variance of the number of cycles in a randomly selected permutation of the first n integers.  相似文献   
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Evaluation of serum SOD and MDA level was done in 21 first episode renal stone formers, 9 recurrent stone formers, 20 patients with obstructive uropathy other than urolithiasis and 12 patients with urinary infection. Twenty-two healthy volunteers were taken as controls. The level of SOD in respective groups was 2.12±0.84, 2.78±0.85, 1.42±0.31, 1.98±0.70 and 2.32±0.62 units/ml and of MDA was 2.61±1.07, 2.69±1.15, 1.65±0.33, 1.33±0.34 and 1.55±0.48 n mol/ml respectively. The results indicate increased peroxidative stressin nephrolithiasis only. Since SOD level was normal in all groups, this increased peroxidative stress in nephrolithiasis should be due to factors other than this one.  相似文献   
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We evaluate feedback methods for oral presentations used in training non-quantitative research skills (literature review and various associated tasks). Training is provided through a credit-bearing module taught to MSc students of banking, economics and finance in the UK. Monitoring oral presentations and providing ‘best practice’ feedback is very resource-intensive. Do we withdraw oral presentations from the module, because best feedback practice is prohibitively expensive in a world of limited resources, or choose a second-best alternative? To what extent might the latter compromise intended learning outcomes? We used the same provision of video feedback for all students but used two verbal feedback regimes. For one regime, we decreased the amount of verbal feedback and increased the number of presentations. The impact was measured by academic outcome, rating scales and questionnaire. Overall satisfaction with the module was very high for both feedback regimes, and there were no statistically significant differences between regimes, suggesting that less resource-intensive methods need not compromise learning outcomes.  相似文献   
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To analyse the association of high sensitivity C-reactive (hsCRP) protein levels and −717A/G single nucleotide polymorphism of CRP with acute myocardial infarction (AMI) in the Indian population. Study population included 100 MI cases wherein 32 patients had experienced previous MI (MI-Group-1), 68 MI cases were recruited at presentation (MI-Group-2) and equal number of age and gender matched healthy individuals. hsCRP levels were determined by ELISA and genotyping of −717A/G was carried out by polymerase chain reaction-based restriction digestion method. The −717A/G genotypes did not influence hsCRP level and their distribution did not differ between groups. However, in the present study hsCRP demonstrated significant correlation with BMI in controls of both the genders and with triglycerides in females of AMI at presentation who otherwise are with low risk profile. Identifying traditional risk factors associated with inflammation may help in controlling the acute event.  相似文献   
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The study aimed to analyze the circulating levels of thrombotic and haemostatic components; tissue factor, tissue factor pathway inhibitor, tissue plasminogen activator and plasminogen activator inhibitor-1 in patients with acute myocardial infarction at presentation (Group 1, n=49), unstable angina and Non-ST elevated MI after treatment (Group 2, n=22), stable angina (Group 3, n=18) and healthy individuals (Group 4, n=31). Significant finding was increase in tissue factor not only in Group 1 (2.0 fold, P=0.001), Group 2 (2.2 fold, P=0.015) but also in Group 3 (1.8 fold, P=0.018) as compared to controls. In Group 1 Plasminogen activator inhibitor-1 increased significantly (35.8%, P=0.02). Tissue factor pathway inhibitor and tissue plasminogen activator demonstrated increase in Group 1 of age<40 years while insignificant changes in elder patients. Increased thrombotic and decreased fibrinolytic conditions in acute myocardial infarction patients were observed. Increase TF in stable angina demonstrates procoagulant status in these patients as well.  相似文献   
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The deployment of Web 2.0 technologies has led to rapid growth of various opinions and reviews on the web, such as reviews on products and opinions about people. Such content can be very useful to help people find interesting entities like products, businesses and people based on their individual preferences or tradeoffs. Most existing work on leveraging opinionated content has focused on integrating and summarizing opinions on entities to help users better digest all the opinions. In this paper, we propose a different way of leveraging opinionated content, by directly ranking entities based on a user’s preferences. Our idea is to represent each entity with the text of all the reviews of that entity. Given a user’s keyword query that expresses the desired features of an entity, we can then rank all the candidate entities based on how well opinions on these entities match the user’s preferences. We study several methods for solving this problem, including both standard text retrieval models and some extensions of these models. Experiment results on ranking entities based on opinions in two different domains (hotels and cars) show that the proposed extensions are effective and lead to improvement of ranking accuracy over the standard text retrieval models for this task.  相似文献   
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This paper assesses how use of smartphones relates to exposure to heterogeneity, political efficacy, and political engagement and suggests a new mediation model that can be applied to mobile communication. Drawing on online survey data collected during the 2012 presidential election in South Korea, this study finds that exposure to heterogeneity and political efficacy jointly mediate the impact of informational uses of smartphones on political participation. The current study also shows that informational uses of smartphones are significantly related to encounters with heterogeneity, political efficacy, and participatory behaviors. Additionally, recreational uses of smartphones were found to have a positive association with exposure to heterogeneity. However, relational uses of smartphones were not associated with democratic outcomes. The findings suggest that smartphones, by increasing the possibility of encountering diversity and subsequently enhancing political efficacy, create an additional pathway to citizen engagement in democratic processes.  相似文献   
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Determination of plasma total homocysteine by high-pressure liquid chromatography (HPLC) usually requires reduction of protein bound or free homocysteine-disulphides into thiols by a reducing agent and the liberated thiols are then derivatized by a fluorescent marker. In this study we have standardized the HPLC method for homocysteine measurement using dithiothreitol (DTT) as reductant. The results of plasma total homocysteine values obtained by HPLC were compared with IMx method. The difference between the two means was statistically insignificant [P=0.616847 (two tail)] Linear regression analysis showed strong correlation between the two methods (r=0.983). Using this method we have analyzed 132 controls and 130 Coronary Heart Disease (CHD) patients for plasma total homocysteine, wherein, the mean plasma total homocysteine levels were 10.51±8.36 and 11.51±10.06 μmol/L respectively. Our research study suggests that DTT method is a simple and inexpensive assay for homocysteine determination in human plasma for research application.  相似文献   
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