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We outline problems and potential solutions for feasible human-machine interfaces using cable-based parallel manipulators for physiotherapy applications. From an engineering perspective, we discuss the design constraints related to acceptance by patients and physiotherapist users. To date, most designs have focused on mobile platforms that are designed to be operated as an end-effector connected to human limbs for direct patient interaction. Some specific examples are illustrated from the authors＇ experience with prototypes available at Laboratory of Robotics and Mechatronics （LARM）, Italy. 相似文献
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提出了一种通过求解L1范数最小化问题来重建四元数信号的算法,并且同时考虑了有噪声和没有噪声2种应用场景.该算法首先将四元数域的L1范数最小化问题转化为实数域的二次锥规划问题,然后通过工具包如SeDuMi来解决这个二次锥规划问题.为了验证所提出算法的正确性和有效性,进行了相关的数值试验.试验结果表明:在没有噪声的情况下,在某些实际可接受的条件下原始信号的精确重建是可以实现的;在有噪声的情况下,所提出的算法对于测量中的加性噪声具有鲁棒性.该算法可以被应用于四元数域基于压缩感知理论的信号重建中. 相似文献
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Sadegh Fattahi Mohammad Karimi Alivije Farhang Babamahmoodi Masomeh Bayani Mahmoud Sadeghi Haddad Zavareh Mohsen Asouri Maryam Lotfi Galia Amirbozorgi Haleh Akhavan-Niaki 《Indian journal of clinical biochemistry : IJCB》2018,33(4):467-472
Hepatitis B virus (HBV) infection is a worldwide health concern which is associated with significant morbidity and mortality. Both viral and host factors have a significant effect on infection, replication and pathogenesis of HBV. The aim of this study was to investigate the effect of CYP2E1 and CYP1A1 genetic variants on susceptibility to HBV. 143 individuals including 54 chronic HBV patients and 89 healthy controls were enrolled in the genotyping procedure. rs2031920 and rs3813867 at CYP2E1 as well as rs4646421 and rs2198843 at CYP1A1 loci were studied in all subjects using PCR–RFLP (restriction fragment length polymorphism) analysis. Both variants at CYP2E1 locus were monomorphic in all studied subjects. Genotype frequency of rs4646421 was significantly different between chronic HBV patients and healthy blood donors (P = 0.04, OR 4.31; 95% CI 1.04–17.7). Furthermore, individuals carrying at least one C allele (CC or CT genotypes) for rs4646421 seemed to have a decrease risk of hepatitis in comparison with TT genotype (P = 0.039). Our results showed a relationship between rs4646421 TT genotype (rare genotype) and the risk for developing chronic HBV infection (four times higher). Further studies are needed to examine the role of CYP1A1 polymorphism in susceptibility to chronic HBV infection. 相似文献
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Nasrin Ziamajidi Hamid Behrouj Roghayeh Abbasalipourkabir Fatemeh Lotfi 《Indian journal of clinical biochemistry : IJCB》2018,33(2):147-153
Diabetes mellitus (DM) is one of the most prevalent diseases in the world, which is strongly associated with liver dysfunction. Hyperglycemia, through an oxidative stress pathway, damages various tissues. Herbal medicine is a good candidate to ameliorate hyperglycemia and oxidative stress. In this study, the effects of aqueous Allium sativum (garlic) extract (AGE) on gene expression of inducible nitric oxide synthases (iNOS) and production of nitric oxide (NO) were evaluated in the liver tissue of diabetic rats. Four groups of rats contained normal control rats, garlic control rats (AGE), Streptozotocin (STZ) + nicotinamide-induced diabetic rats (DM), and diabetic rats treated with garlic (DM + AGE). Glucose levels and liver enzymes activities were determined by colorimetric assay in the serum. Gene expression of iNOS by real-time PCR, NO levels by Griess method, oxidative stress parameters by spectrophotometric method and histopathological examination by hematoxylin and eosin staining method were evaluated in the liver tissues. Glucose levels, activities of liver enzymes, oxidative stress markers, iNOS gene expression, and NO production increased significantly in diabetic rats in comparison with control rats, whereas after oral administration of garlic, these parameters decreased significantly, close to the normal levels. Hence, the beneficial effects of garlic on the liver injury of diabetes could be included in the hypoglycaemic and antioxidant properties of garlic via a decrease in gene expression of iNOS and subsequent NO production. 相似文献
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为了寻找利用小波散射网络进行彩色图像处理的最佳彩色空间,用小波散射网络对KTH_TIPS_COL彩色图像数据库进行了图像纹理分类研究.采用将彩色图像从RGB彩色空间转换到其他各种彩色空间的方法,研究了彩色空间的选择对于小波散射网络用于彩色图像纹理分类的影响.实验结果表明:在不同的彩色空间对彩色图像纹理进行分类,分类成功率往往差别较大;在基于竞争机制的红绿蓝彩色空间中进行小波散射变换比其他彩色空间具有更好的分类性能.考虑到彩色空间可以互相转换,对于彩色纹理图像的分类,推荐将彩色空间转化到基于竞争机制的红绿蓝彩色空间后再输入小波散射网络. 相似文献
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Hori Ghaneialvar Leila Soltani Hamid Reza Rahmani Abbas Sahebghadam Lotfi Masoud Soleimani 《Indian journal of clinical biochemistry : IJCB》2018,33(1):46-52
Mesenchymal stem cells are multipotent cells capable of replicating as undifferentiated cells, and have the potential of differentiating into mesenchymal tissue lineages such as osteocytes, adipocytes and chondrocytes. Such lineages can then be used in cell therapy. The aim of present study was to characterize bone marrow derived mesenchymal stem cells in four different species, including: sheep, goat, human and mouse. Human bone-marrow mesenchymal stem cells were purchased, those of sheep and goat were isolated from fetal bone marrow, and those of mouse were collected by washing bone cavity of femur and tibia with DMEM/F12. Using flow-cytometry, they were characterized by CD surface antigens. Furthermore, cells of third passage were examined for their osteogenic and adipogenic differentiation potential by oil red and alizarin red staining respectively. According to the results, CD markers studied in the four groups of mesenchymal stem cells showed a different expression. Goat and sheep expressed CD44 and CD166, and weakly expressed CD34, CD45, CD105 and CD90. Similarly, human and mouse mesenchymal cells expressed CD44, CD166, CD105 and CD90 whereas the expression of CD34 and CD45 was negative. In conclusion, although all mesenchymal stem cells display plastic adherence and tri-lineage differentiation, not all express the same panel of surface antigens described for human mesenchymal stem cells. Additional panel of CD markers are necessary to characterize regenerative potential and possible application of these stem cells in regenerative medicine and implantology. 相似文献
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