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1.
Abstract

Carnosine was originally discovered in skeletal muscle, where it exists in larger amounts than in other tissues. The majority of research into the physiological roles of carnosine have been conducted on skeletal muscle. Given this and the potential for muscle carnosine content to be increased with supplementation, there is now a large body of research examining the ergogenic effects (or otherwise) of carnosine. More recent research, however, points towards a potential for carnosine to exert a wider range of physiological effects in other tissues, including the brain, heart, pancreas, kidney and cancer cells. Taken together, this is suggestive of a potential for carnosine to have therapeutic benefits in health and disease, although this is by no means without complication. Herein, we will provide a review of the current literature relating to the potential therapeutic effects of carnosine in health and disease.  相似文献   
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Book reviews     
Association of Research Libraries  相似文献   
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The most frequently requested accommodation among students with learning disabilities (LD) in postsecondary settings is extended test time. The frequency with which this accommodation is requested and granted compels disability service providers to become knowledgeable about the factors that influence the need for, and appropriateness of, the accommodation. Moreover, the synthesis of these factors becomes the basis for determining if the accommodation is reasonable under federal law. The purpose of this article is to present a step‐by‐step model to be used as a decision‐making process when considering the accommodation of extended test time for postsecondary students with LD. The model is designed to assist disability service providers in the analysis and synthesis of information collected from (1) the student's diagnostic evaluation, (2) the course or classroom test to be accommodated, and (3) student interviews. A list of diagnostic tests from the four most frequently administered test batteries used with adults is provided, along with a concise explanation of how characteristics of LD impact reading, writing, and math, and relate to the need for extended time. This information can be used to determine if extended test time is a reasonable accommodation and to estimate how much additional time to provide.  相似文献   
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Field work and structured interviews with 139 foreign sojourners in India were analyzed to describe the socialization of aliens into their role. Attitude scales measuring favorability toward the host country and people were also examined in relation to the respondent's occupational status and elapsed time in India. The results from the field work and interviews suggest that the privileges and high status accorded many Western visitors may contribute to the visitors' derogation of their hosts, a process which is often subtle but unmistakable. The visitors appear to become socialized into the world of aliens rather than the world of their hosts. The higher the visitor's status and the longer the elapsed time in India, the more pronounced these patterns appear. While the correlational nature of the study makes it impossible to determine whether persons with initially unfavorable attitudes are selected into the high status positions or whether the positions themselves create such attitudes, it appears reasonable to conclude that there would be less derogation and alienation if the lures of status and money were removed; persons would be neither selected nor influenced by such factors.  相似文献   
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This article introduces emergent memory, a conceptual extension to rhetorics of public memory, to describe memory’s genesis in sites built without commemorative commitments. Examining Detroit’s “8 Mile Wall,” a site built to reinforce segregated housing, this project argues the rhetorical tenets of emergent memory present in this space. As a relic of segregated history, the wall symbolically recalls the city’s controversial past, but has recently been the subject of a local mural project to redefine the wall’s purpose. Some consider this a step toward reclamation, as it visually repositions the disturbing remnant. For others, the murals simply cannot overwrite troubling memories of the city’s discriminatory history. This essay uses emergent memory to describe how the wall’s complicated mnemonic legacy simultaneously harkens to a difficult history and how the mural additions use that same legacy to convey an optimistic future for Detroit and those marked by this urban space.  相似文献   
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