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To study an environmental or biological solution, it is essential to separate its constituents. In this study, a 3D-deformable dynamic microfilter was developed to selectively separate the target substance from a solution. This microfilter is a fine metallic nickel structure fabricated using photolithography and electroplating techniques. It is gold-coated across its entire surface with multiple slits of 10–20 μm in width. Its two-dimensional shape is deformed into a three-dimensional shape when used for fluid separation due to hydrodynamic forces. By adjusting the pressure applied to the microfilter, the size of the gap created by deformation can be changed. To effectively isolate the target substance, the relationship between the solution flow rate and the extent of microfilter deformation was investigated. The filtration experiments demonstrated the microfilter’s ability to isolate the target substance with elastic deformation without undergoing plastic deformation. Additionally, modification of the microfilter surface with nucleic acid aptamers resulted in the selective isolation of the target cell, which further demonstrates the potential application of microfilters in the isolation of specific components of heterogeneous solutions.  相似文献   
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ABSTRACT

The purpose of this paper is to clarify the actual conditions of youth in social difficulties in Japan and to examine the characteristics and meanings of ‘educational support’ for them from the viewpoint of literacy theory as a social practice. My colleagues and I carried out a four-year qualitative study of several private groups supporting young people from 2012 to 2015. In this study, we visited the groups and conducted semi-structured interviews with young learners (aged from 16 to 23) and their supporters. It became clear during the interviews that most young learners had not received sufficient basic education because of their delinquency or truancy, and they had had very few opportunities to build relationships of trust with those around them. The elements of the support that is needed are clarified in this study as follows: (1) building relationships of trust with young learners, (2) nurturing learners’ motivation and/or self-confidence, (3) emphasizing learners’ ideas, interests and literacies embedded in their everyday lives. These points show that ‘educational support’ for youth in social difficulties should by no means only be about the transmission of skills or fragmentary knowledge, but also the cultivation of motivation for learning and/or self-confidence based on relationships of trust.  相似文献   
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Females, as compared with males, have a higher proportion of injuries in the foot region. However, the reason for this gender difference regarding foot injuries remains unclear. This study aimed to investigate gender differences associated with rearfoot, midfoot, and forefoot kinematics during running. Twelve healthy males and 12 females ran on a treadmill. The running speed was set to speed which changes from walking to running. Three-dimensional kinematics of rearfoot, midfoot, and forefoot were collected and compared between males and females. Furthermore, spatiotemporal parameters (speed, cadence, and step length) were measured. In the rearfoot angle, females showed a significantly greater peak value of plantarflexion and range of motion in the sagittal plane as compared with males (effect size (ES)?=?1.55 and ES?=?1.12, respectively). In the midfoot angle, females showed a significantly greater peak value of dorsiflexion and range of motion in the sagittal plane as compared with males (ES?=?1.49 and ES?=?1.71, respectively). The forefoot peak angles and ranges of motion were not significantly different between the genders in all three planes. A previous study suggested that a gender-related difference in excessive motions of the lower extremities during running has been suggested as a contributing factor to running injuries. Therefore, the present investigation may provide insight into the reason for the high incidence of foot injuries in females.  相似文献   
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Performer autonomy has been shown to contribute to effective motor performance and learning. Autonomy support is therefore a key factor in the OPTIMAL theory of motor learning (Wulf, G., & Lewthwaite, 2016). The purpose of the present study was to examine whether supporting individuals’ need for autonomy by giving them choices would increase movement efficiency. Such a finding would be consistent with the OPTIMAL theory prediction that autonomy facilitates the coupling of goals and actions. Participants (N = 32) were asked to run at a submaximal intensity (65% of VO2 max) for 20 minutes. Before the run, participants in a choice group were able to choose 5 of 10 photos as well as the order in which they would be shown to them on a computer screen during the run. Control group participants were shown the same photos, in the same order, chosen by their counterparts in the choice group. Throughout the run, oxygen consumption and heart rate were significantly lower in the choice group than the control group. Thus, providing autonomy support resulted in enhanced running efficiency. The present findings are in line with the notion that autonomy facilitates goal-action coupling.  相似文献   
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Because previous studies have suggested that there is a relationship between injury risk and inter-segment coordination, quantifying coordination between the segments is essential. Even though the midfoot and forefoot segments play important roles in dynamic tasks, previous studies have mostly focused on coordination between the shank and rearfoot segments. This study aimed to quantify coordination among rearfoot, midfoot, and forefoot segments during running. Eleven healthy young men ran on a treadmill. The coupling angle, representing inter-segment coordination, was calculated using a modified vector coding technique. The coupling angle was categorised into four coordination patterns. During the absorption phase, rearfoot–midfoot coordination in the frontal planes was mostly in-phase (rearfoot and midfoot eversion with similar amplitudes). The present study found that the eversion of the midfoot with respect to the rearfoot was comparable in magnitude to the eversion of the rearfoot with respect to the shank. A previous study has suggested that disruption of the coordination between the internal rotation of the shank and eversion of the rearfoot leads to running injuries such as anterior knee pain. Thus, these data might be used in the future to compare to individuals with foot deformities or running injuries.  相似文献   
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