Connecting inside out: Development of the social brain in infants and toddlers with a focus on myelination as a marker of brain maturation     

Nora Schneider  Elizabeth Greenstreet  Sean C. L. Deoni 《Child development》2022,93(2):359-371

Early childhood is a sensitive period for learning and social skill development. The maturation of cerebral regions underlying social processing lays the foundation for later social-emotional competence. This study explored myelin changes in social brain regions and their association with changes in parent-rated social-emotional development in a cohort of 129 children (64 females, 0–36 months, 77 White). Results reveal a steep increase in myelination throughout the social brain in the first 3 years of life that is significantly associated with social-emotional development scores. These findings add knowledge to the emerging picture of social brain development by describing neural underpinnings of human social behavior. They can contribute to identifying age-/stage-appropriate early life factors in this developmental domain.  相似文献   

The Unintentional Effects on Body Donation Programs of a Competency-Based Curriculum in Postgraduate Medical Education     

Geoffroy P.J.C. Noël  Joseph Dubé  Gabriel Venne 《Anatomical sciences education》2021,14(5):675-681

As medical programs place increasing importance on competency-based training and surgical simulations for residents, anatomy laboratories, and body donation programs find themselves in a position of adapting to changing demands. To better assess the demand for “life-like” cadaveric specimens and evaluate the possible impacts that competency-based medical education could have upon the body donation program of McGill University, Canada, the authors tracked, over the course of the last 10 years, the number of soft-embalmed specimens, along with the number of teaching sessions and the residents enrolled in competency-based programs that are using cadaveric material. The results reveal that the number of soft-embalmed specimens used within residency training increased from 5 in 2009 to 35 in 2019, representing an increase from 6% of bodies to 36.5% of the total number of body donors embalmed in this institution. Correspondingly, the number of annual teaching sessions for residents increased from 19 in 2012 to 116 in 2019. These increases in teaching are correlated with increasing number of residents enrolled in competency-based programs over the last 3 years (Pearson r ranging from 0.9705 to 0.9903, and R² ranging from 0.9418 to 0.9808). Those results suggest that the new skill-centered curricula which require residents to perform specific tasks within realistic settings, exhibit a growing demand for “life-like” cadaveric specimens. Institutions’ body donation programs must, therefore, adapt to those greater need for cadaveric specimens, which presents many challenges, ranging from the logistical to the ethical.  相似文献   

Early Childhood Parenting Predicts Late Childhood Brain Functional Connectivity During Emotion Perception and Reward Processing     

Daniel C. Kopala-Sibley  Marilyn Cyr  Megan C. Finsaas  Jonathan Orawe  Anna Huang  Nim Tottenham  Daniel N. Klein 《Child development》2020,91(1):110-128

Seventy-nine 3-year olds and their mothers participated in a laboratory-based task to assess maternal hostility. Mothers also reported their behavioral regulation of their child. Seven years later, functional magnetic resonance imaging data were acquired while viewing emotional faces and completing a reward processing task. Maternal hostility predicted more negative amygdala connectivity during exposure to sad relative to neutral faces with frontal and parietal regions as well as more negative left ventral striatal connectivity during monetary gain relative to loss feedback with the right posterior orbital frontal cortex and right inferior frontal gyrus. In contrast, maternal regulation predicted enhanced cingulo-frontal connectivity during monetary gain relative to loss feedback. Results suggest parenting is associated with alterations in emotion and reward processing circuitry 7–8 years later.  相似文献   

基于深度学习的中文专利自动分类方法研究   总被引：2，自引：0，他引：2  

吕璐成  韩涛  周健  赵亚娟 《图书情报工作》2020,64(10):75-85

[目的/意义] 面向当前国内专利审查和专利情报分析工作中对于海量专利分类的客观需求，设计了7种基于深度学习的专利自动分类方法，对比各种方法的分类效果，从而助力专利分类效率和效果的提升。[方法/过程] 针对传统机器学习方法存在的缺陷，基于Word2Vec、CNN、RNN、Attention机制等深度学习技术，考虑专利文本语序特征、上下文特征以及分类关键特征，设计Word2Vec+TextCNN、Word2Vec+GRU、Word2Vec+BiGRU、Word2Vec+BiGRU+TextCNN等7种深度学习模型，以中国专利为例，选取IPC主分类号的"部"作为分类依据，对比这7种模型与3种传统分类模型在中文专利分类任务中的效果。[结果/结论] 实证研究效果显示，采用考虑语序特征、上下文特征及强化关键特征的深度学习方法进行中文专利分类具有更优的分类效果。  相似文献   

From structure to function: unveiling the structure of the Nav channel–toxin complex     

Zhuan Zhou  Zuying Chai  Changhe Wang 《国家科学评论(英文版)》2019,6(5):859

  相似文献   

记忆场、传统村落与我们的责任——档案部门参与村落记忆场保护的价值与策略     

周林兴  林腾虹 《档案管理》2020,(3):39-41

传统村落拥有丰富的自然和文化资源,凝结着历史的记忆,是社会文明的直接见证者。随着城镇化进程的推进,传统村落逐步消融在时代的印迹里。为促进传统村落在新时代的焕发新生,文章借助法国历史学家皮埃尔·诺拉的记忆之场理论,指出传统村落在历史、时间、变迁中凝聚成具有象征意义的记忆场。在此基础上文章剖析了档案部门参与村落记忆场保护的意义,阐释了村落记忆场赓续乡村记忆、留住乡情乡愁、传承文化遗产的功能,并提出了档案部门就如何推动村落记忆场实现功能最大化的策略,以期使档案部门更好地承担起传承、保护、赓续传统村落的主体责任。  相似文献   

The Influence of Hygroscopic Materials on the Fluctuation of Relative Humidity in Museums Located in Historical Buildings     

C. Ferreira  V. P. de Freitas 《文物保护研究》2020,65(3):127-141

ABSTRACT

The preservation of artefacts in museum collections is profoundly affected by fluctuations in temperature and, especially, relative humidity (RH). Since the late nineteenth century, many studies have been carried out on the best way to control hygrothermal conditions. In old buildings located in maritime temperate climate zones (such as Portugal) with strong thermal inertia, and which have low ventilation rate (relative to the volume and number of visitors), daily and seasonal hygroscopic inertia may help to assure the maintenance of RH stabilization conditions. The use of expensive active systems may be minimized through the passive behaviour of internal finishing building materials. This work presents the results of an experimental laboratory study conducted in a flow chamber to demonstrate the enormous potential of hygroscopic materials in stabilizing interior relative humidity. Based in these results and in-situ monitoring in a museum housed in a building, located in Porto, with a typical construction of the 1950s (granite masonry and reinforced concrete slabs), a numerical analysis was done to quantify the influence of hygroscopic materials in stabilizing the interior relative humidity.  相似文献   

“健康中国2030”战略下健康数据协同治理体系研究     

周知  胡昌平 《图书情报工作》2021,65(1):102-109

[目的/意义] 提升公民健康水平是经济社会发展到一定程度后的必然要求，健康数据协同治理体系的构建有助于从信息科学角度达成这一要求，治理体系需要以国家战略为宏观指导，全方位服务于公民健康水平提升的总体目标。[方法/过程] 通过对《"健康中国2030"规划纲要》文本精神的领会，在分析了各治理主体对健康信息治理需求的基础上，提出一种面向"健康中国2030"战略的健康数据协同治理体系，并针对关键环节提出保障措施。[结果/结论] 协调各层级、各部门与各利益主体的健康数据治理体系构建与保障，有助于在推动国家健康战略目标的同时实现健康数据的社会价值，拓展健康信息学的研究范畴。  相似文献   

Proclaiming Library Worth in a Program Prioritization Process at a Mid-Sized Public University     

Michelle J. Oh  Robin J. Harris  Lisa C. Wallis 《图书馆管理杂志》2020,60(3):250-262

Abstract

In an economic climate when colleges can no longer presume that legislators see institutions of higher learning as tacit public goods, institutions around the country are facing budget cuts. This article presents a case study of the experience of a mid-sized public state university and its Library in a budget crisis undergoing a university-wide program prioritization process. The authors review the process of writing three reports on the Library’s value, along with the approach to engaging staff in the process including a retreat. This article raises questions about what every library should consider assessing and provide tools for libraries navigating similar terrain.  相似文献   

奥运会对提升国民凝聚力心理因素的分析   总被引：3，自引：0，他引：3  

周成林  陈立新 《沈阳体育学院学报》2003,(2):47-49

以哲学和社会学为视角 ,以社会心理学、心理学理论和体育学为基础 ,运用文献法、访谈法和比较法等方法 ,对奥运会提升国民心理凝聚力、凝聚力构成因素及条件、产生社会效益等问题进行分析 ,认为奥运会对振奋民族精神、唤醒民族意识、维系民族情感具有显著作用 ,同时也丰富凝聚力理论外延与内涵。  相似文献