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Colak T Akca T Turkmenoglu O Canbaz H Ustunsoy B Kanik A Aydin S 《Journal of Zhejiang University. Science. B》2008,9(4):319-323
Objective: This prospective randomized clinical trial was conducted to evaluate the necessity of drainage after total thyroidectomy or lobectomy for benign thyroidal disorders. Methods: A total of 116 patients who underwent total thyroidectomy or lobectomy for benign thyroidal disorders were randomly allocated to be drained or not. Operative and postoperative outcomes including operating time, postoperative pain assessed by visual analogue scale (VAS), total amount of intramuscular analgesic administration, hospital stay, complications, necessity for re-operation and satisfaction of patients were all assessed. Results: The mean operating time was similar between two groups (the drained and non-drained groups). The mean VAS score was found to be significantly low in the non-drained group patients in postoperative day (POD) 0 and POD 1. The mean amount of intramuscular analgesic requirement was significantly less in the non-drained group. One case of hematoma, two cases of seroma and three cases of transient hypoparathyroidism occurred in the non-drained group, whereas one case of hematoma, two cases of seroma, two cases of wound infections and two cases of transient hypoparathyroidism occurred in the drained group. No patient needed re-operation for any complication. The mean hospital stay was significantly shorter and the satisfaction of patients was superior in the non-drained group. Conclusion: These findings suggest that postoperative complications cannot be prevented by using drains after total thyroidectomy or lobectomy for benign thyroid disorders. Furthermore, the use of drains may increase postoperative pain and the analgesic requirement, and prolong the hospital stay. In the light of these findings, the routine use of drains might not be necessary after thyroid surgery for benign disorders. 相似文献
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Fatma Emel Ko?ak Mustafa Y?ntem ?zlem Yücel Mustafa ?ilo ?zlem Gen? Ayfer Meral 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2013,23(2):206-210
Introduction:
Today, the pneumatic tube transport system (PTS) is used frequently because of its advantages related to timing and speed. However, the impact of various types of PTS on blood components is unknown. The aim of this study was to examine the influence of PTS on the quality of routine blood cell counts, erythrocyte sedimentation, and certain blood coagulation tests.Materials and methods:
Paired blood samples were obtained from each of 45 human volunteers and evaluated by blood cell count, erythrocyte sedimentation, and several coagulation tests, including prothrombin time (PT) and activated partial thromboplastin time (aPTT). Blood samples were divided into 2 groups: Samples from group 1 were transported to the laboratory via the PTS, and samples from group 2 were transported to the laboratory manually. Both groups were evaluated immediately by the tests listed above.Results:
The blood sample test results from groups 1 and 2 were evaluated and compared. No statistically significant differences were observed (P = 0.069–0.977).Conclusion:
The PTS yielded no observable effects on blood cell counts, erythrocyte sedimentation, or PT and aPTT test results. We concluded that the PTS can be used to transport blood samples and yield reliable results for blood cell counts, erythrocyte sedimentation, and several coagulation tests. 相似文献3.
Rebecca McGraw Kathleen Lynch Yusuf Koc Ayfer Budak Catherine A. Brown 《Journal of Mathematics Teacher Education》2007,10(2):95-121
In this study, we consider the potential of multimedia cases as tools for teacher professional development. Specifically,
we examined online and face-to-face discussions that occurred within groups composed of pre-service mathematics teachers,
in-service mathematics teachers, mathematicians, and mathematics teacher educators. Discussions within these heterogeneous
groups tended to focus on issues of classroom implementation of the tasks shown in the multimedia case. Secondary foci of
discussion included task characteristics and appropriateness of tasks for engaging students in thinking about mathematical
concepts and processes. Analysis of contributions to discussions across group member type revealed differences that suggest
that the variety of backgrounds and experiences of group members can blend in ways that support rich and critical discussions
of mathematics, teaching, and learning. 相似文献
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Alandeom W. Oliveira Huseyin Colak Valarie L. Akerson 《Cultural Studies of Science Education》2009,4(1):149-155
We would like to thank our commentators Reis, Ercikan and Alper for their insightful comments on our research study and respond
in brief to a few of their criticisms. More specifically, we would like to address what we consider to be the three main issues
they raise with regard to the practices of curriculum translation and implementation across languages, namely viewing speakers’
intentions as a mode of signification in discourse analysis, exploring curriculum translation through an interpretive research
approach, and establishing the validity of research on curriculum translation.
相似文献
| Alandeom W. OliveiraEmail: |
5.
Alandeom W. Oliveira Huseyin Colak Valarie L. Akerson 《Cultural Studies of Science Education》2009,4(1):89-132
In this study we examine how elementary teachers in Brazil and Turkey approached the translation and subsequent classroom
implementation of an instructional activity that promotes environmental awareness through a combination of student role playing
and teacher oral delivery of an environmental story about river pollution. A discourse analysis showed that translation into
Portuguese was literal, an approach that fostered a classroom implementation that emphasized detached transmission of knowledge
(the teacher frequently interrupted her delivery to provide textual, contextual and recontextualizing information to students).
In contrast, translation into Turkish was free, that is, with many modifications that led to a decontextualized and detached
text. Implementation of this text was focused on the creation of student involvement, being dominated by oral strategies such
as religious analogies (heaven and hell), and parallel repetitions of statements of shared guilt. Based on these findings,
it was concluded that neither translation promoted an equivalent form of environmental instruction (i.e., involved transmission
of environmental knowledge). Furthermore, an argument is made that effective translation requires that original and translated
curricula foster analogous levels of involvement (or detachment) as well as equivalent forms of classroom relationships and
social roles (pragmatic equivalence).
相似文献
| Alandeom W. OliveiraEmail: |
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Colak E Majkic-Singh N Zoric L Radosavljevic A Kosanovic-Jakovic N 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2012,22(1):39-48
Age-related macular degeneration (AMD) is a complex, degenerative and progressive disease involving the multiple genetic and environmental factors that can result in severe visual loss. The etiology of AMD is not well understood. Many theories exist and feature mechanisms of oxidative stress, atherosclerotic-like changes, genetic predisposition and inflammation. The most recent clinical studies appointed to a great role of inflammation and C-reactive protein (CRP) in the pathogenesis of AMD. There is a large body of evidence indicating the association of CRP with endothelial dysfunction, oxidative stress and production of reactive oxygen species (ROS), as well as with lipid status disorder in AMD patients. According to recent studies, CRP is definitely not only the inflammatory marker but also a mediator of development of the vascular disorders in the retinal circulation. The results obtained from the present studies may help our understanding the pathogenesis of the retinal vascular disease associated with high levels of CRP. 相似文献
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Canbaz H Dirlik M Colak T Ocal K Akca T Bilgin O Tasdelen B Aydin S 《Journal of Zhejiang University. Science. B》2008,9(6):482-488
Objective: To investigate the effect of recurrent laryngeal nerve (RLN) identification on the complications after total thyroidectomy and lobectomy. Methods: Total 134 consecutive patients undergoing total thyroidectomy or thyroid lobectomy from January 2003 to November 2004 were investigated retrospectively. Patients were divided into two groups: RLN identified (Group A) or not (Group B). The two groups were compared for RLN injury and hypocalcaemia. Results: The numbers of patients and nerves at risk were 71 and 129 in Group A, and 63 and 121 in Group B, respectively. RLN injury in Group A (0) was significantly lower than that in Group B (5[7.9%]) patients, 7 [5.8%] nerves) for the numbers of patients (P=-0.016) and nerves at risk (P=0.006). Temporary hypocalcaemia was significantly higher in Group A than in Group B (14 [24.1%] vs 6 [10.3%], P=0.049).Permanent complications in Group B were significantly higher than those in Group A (13 [20.6%] vs 4 [5.6%], P=0.009). Conclusion: RLN injury was prevented and permanent complications were decreased by identifying the whole course and branches of the recurrent laryngeal nerve during total thyroidectomy. 相似文献
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The purpose of this study is to introduce and evaluate a method for generating reading comprehension items using template-based automatic item generation. To begin, we describe a new model for generating reading comprehension items called the text analysis cognitive model assessing inferential skills across different reading passages. Next, the text analysis cognitive model is used to generate reading comprehension items where examinees are required to read a passage and identify the irrelevant sentence. The sentences for the generated passages were created using OpenAI GPT-3.5. Finally, the quality of the generated items was evaluated. The generated items were reviewed by three subject-matter experts. The generated items were also administered to a sample of 1,607 Grade-8 students. The correct options for the generated items produced a similar level of difficulty and yielded strong discrimination power while the incorrect options served as effective distractors. Implications of augmented intelligence for item development are discussed. 相似文献
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Fatma Emel Kocak Ozben Ozden Isiklar Havva Kocak Ayfer Meral 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2015,25(1):57-63
Introduction
Measurements of blood ethanol concentrations must be accurate and reliable. The most important factors affecting blood ethanol stability are temperature and storage time. In this study, we aimed to compare ethanol stability in plasma samples at -20 °C for the different storage periods.Materials and methods
Blood samples were collected from intoxicated drivers (N = 80) and initial plasma ethanol concentrations were measured immediately. Plasma samples were then stored at -20 °C and re-assessed after 2, 3, 4, or 5 months of storage. Differences between the initial and stored ethanol concentrations in each group (N = 20) were analyzed using Wilcoxon matched-pairs test. The deviation from the initial concentration was calculated and compared with Clinical Laboratory Improvement Amendments (CLIA’88) Proficiency Testing Limits. Relationships between the initial concentrations and deviations from initial concentrations were analyzed by Spearman’s correlation analysis. For all statistical tests, differences with P values of less than 0.05 were considered statistically significant.Results
Statistically significant differences were observed between the initial and poststorage ethanol concentrations in the overall sample group (P < 0.001). However, for the individual storage duration groups, analytically significant decreases were observed only for samples stored for 5 months, deviations from the initial concentrations exceeded the allowable total error (TEa). Ethanol decreases in the other groups did not exceed the TEa.Conclusion
According to our results, plasma ethanol samples can be kept at -20 °C for up to 3-4 months until re-analysis. However, each laboratory should also establish its own work-flow rules and criterion for reliable ethanol measurement in forensic cases.Key words: preanalytical phase, ethanol, stability, storage temperature 相似文献10.
Ayfer Colak Burak Toprak Nese Dogan Fusun Ustuner 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2013,23(3):321-325
Introduction:
Studies about vitamin D [25(OH)D] stability in plasma are limited and preanalytical variables such as tube type may affect results. We aimed to evaluate effect of storage conditions, sample type and some preanalytical variables on vitamin D concentration.Materials and methods:
Blood samples from 15 healthy subjects were centrifuged at different temperatures and stored under different conditions. Serum and plasma 25(OH)D difference, effect of centrifugation temperature and common storage conditions were investigated.Results:
There was no difference between serum and plasma vitamin D concentration. Centrifugation temperature had no impact on vitamin D concentration. 25(OH)D is stable under common storage conditions: 4 hours at room temperature, 24 hours at 2–8 °C, 7 days at −20 °C, 3 months at −80 °C.Conclusion:
Vitamin D does not require any special storage conditions and refrigeration. Both serum and plasma can be used for measurement. 相似文献
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