排序方式： 共有11条查询结果，搜索用时 19 毫秒
1.
Ishrat Kareem S. A. Jaweed J. S. Bardapurkar V. P. Patil 《Indian journal of clinical biochemistry : IJCB》2004,19(2):124-127
The present study was undertaken in 100 subjects, 30 diabetics without complication (group I), 40 diabetics with retinopathy
(group II) and 30 non diabetic as normal control group (group III). Blood sugar levels, magnesium, cholesterol and triglyceride
were analyzed from plasma and serum. The results were correlated with degree of diabetic control from the levels of glycosylated
hemoglobin. Serum magnesium levels in group II were found to be significantly lowered than in group I. There was also significant
difference in magnesium levels of group I and group III. We found a significant correlation between the glycosylated hemoglobin
and magnesium levels in our study.
The results also indicate that the patients with diabetic retinopathy showed significant rise in serum cholesterol and triglyceride.
Probably hypomagnesemia and increased serum cholesterol and triglyceride levels are responsible for microvascular changes
in diabetes leading to retinopathy. The purpose of this study was thus to gather information about the degree of control of
diabetes and magnesium status. 相似文献
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Ishrat Husain Ramesh Chander Jitendra Kumar Saxena Abbas Ali Mahdi Farzana Mahdi 《Indian journal of clinical biochemistry : IJCB》2015,30(1):72-77
The antidyslipidemic activity of Ocimum sanctum leaf extract was studied in streptozotocin induced diabetic rats. In this model, there was significant increase in plasma markers of diabetic-dyslipidemia following diminution of lipid metabolizing enzymes. Oral administration of leaf extract (500 mg/kg b.w.p.o.) for 15 days resulted in significant decrease in diabetogenic and dyslipidemia parameters; namely blood glucose, glycosylated hemoglobin, lipid peroxide, free fatty acids, small dense low density lipoprotein, lipid and protein components of plasma lipoproteins, adipose and liver. The regulation of lipids was accompanied by stimulation of postheparin lipolytic activity, reactivation of lecithin cholesterol acyl transferase and hepatic lipoprotein lipase enzymes. The results of the present study demonstrated antidyslipidemic and antioxidant activities in leaf extract of O. sanctum which could be used in prevention of diabetic-dyslipidemia and related complications. 相似文献
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K. Husain R. N. Sahu R. Rahman A. Nair 《Indian journal of clinical biochemistry : IJCB》1995,10(1):45-47
The levels of norepinephrine (NE), dopamine (DA) serotonin (5-HT) and its metabolite 5-hydroxyindole acetic acid (5-HIAA)
have been determined in the cerebrospinal fluid (CSF) of normal (n=25) and suicidal attempt cases (n=30). A significant decrease
in the level of NE (p<0.01), 5-HT(p<0.001) and 5-HIAA (p<0.001) in the CSF of suicide attempt cases were observed as compared
to normal controls. It is concluded that CSF 5-HIAA level which is drastically depleted may be used as an early biochemical
indicator of suicidal attempt so that it may be treated by the drugs which can enhance the suppressed neurotransmitter activity. 相似文献
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Rachel Muehrer Jennifer Jenson Jeremy Friedberg Nicole Husain 《Cultural Studies of Science Education》2012,7(4):783-805
Simulations and games are not new artifacts to the study of science in secondary school settings (Hug, Kriajcik and Marx 2005), however teachers remain skeptical as to their value, use and appropriateness (Rice 2006). The difficulty is not only the design and development of effective play environments that produce measurable changes in knowledge and/or understanding, but also in their on-the-ground use (Jaipal and Figg 2010). This paper reports on the use of a science-focused video game in five very different secondary school settings in Ontario, Canada. A mixed-methods approach was used in the study, and included data gathered on general gameplay habits and technology use, as well as informal interviews with teachers and students who played the game. In total, 161 participants played a series of games focused on the ??life of a plant??, and were given both a pre and post quiz to determine if the game helped them retain and/or change what they knew about scientific processes like plant cell anatomy and photosynthesis. Participants showed statistically significant improvement on quizzes that were taken after playing the game for approximately one-hour sessions, despite difficulties in some cases both accessing and playing the game for the full hour. Our findings also reveal the ongoing challenges in making use of technology in a variety of school sessions, even when using a browser-based game, that demanded very little other than a reliable internet connection. 相似文献
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Syed Mazher Husain M. P. J. S. Anandaraj 《Indian journal of clinical biochemistry : IJCB》1997,12(2):142-145
DNA samples from a family (parents and a son) with hereditary persistence of fetal hemoglobin (HPFH) condition were subjected to amplification of a 1.214 kbp DNA fragment from β-globin gene using polymerase chain reaction (PCR). The aim of this study was to identify the type of HPFH i.e. deletional or non deletional. Non deletional type of HPFH was identified in two samples and moreover, these samples were found to be associated with 619bp β°-thalassemia deletion. This is the first report on the association of non deletional HPFH with 619bp β°-thalassemia deletion. 相似文献
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Zariyantey Abdul Hamid Siti Balkis Budin Ng Wen Jie Asmah Hamid Khairana Husain Jamaludin Mohamed 《Journal of Zhejiang University. Science. B》2012,13(3):176-185
Paracetamol (PCM) overdose can cause nephrotoxicity with oxidative stress as one of the possible mechanisms mediating the
event. In this study, the effects of ethyl acetate extract of Zingiber zerumbet rhizome [200 mg per kg of body weight (mg/kg) and 400 mg/kg] on PCM-induced nephrotoxicity were examined. Rats were divided
into five groups containing 10 rats each. The control group received distilled water while other groups were treated with
extract alone (400 mg/kg), PCM alone (750 mg/kg), 750 mg/kg PCM+200 mg/kg extract (PCM+ 200-extract), and 750 mg/kg PCM+400
mg/kg extract (PCM+400-extract), respectively, for seven consecutive days. The Z. zerumbet extract was given intraperitoneally concurrent with oral administration of PCM. Treatment with Z. zerumbet extract at doses of 200 and 400 mg/kg prevented the PCM-induced nephrotoxicity and oxidative impairments of the kidney, as
evidenced by a significantly reduced (P<0.05) level of plasma creatinine, plasma and renal malondialdehyde (MDA), plasma protein carbonyl, and renal advanced oxidation
protein product (AOPP). Furthermore, both doses were also able to induce a significant increment (P<0.05) of plasma and renal levels of glutathione (GSH) and plasma superoxide dismutase (SOD) activity. The nephroprotective
effects of Z. zerumbet extract were confirmed by a reduced intensity of renal cellular damage, as evidenced by histological findings. Moreover,
Z. zerumbet extract administered at 400 mg/kg was found to show greater protective effects than that at 200 mg/kg. In conclusion, ethyl
acetate extract of Z. zerumbet rhizome has a protective role against PCM-induced nephrotoxicity and the process is probably mediated through its antioxidant
properties. 相似文献
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Syed Mazher Husain M. P. J. S. Anandaraj 《Indian journal of clinical biochemistry : IJCB》1995,10(2):122-125
Hemoglobin E (beta-26Glutamic acid→Lysine) is the second most prevalent hemoglobin variant in the world. 293 blood samples from cases referred from several hospitals in the region of Andhra Pradesh were screened for the detection of hemoglobinopathies. Four samples were found to be in heterozygous state for Hb E condition. Mutation in two of these heterozygotes was analysed using a 722 base pair (bp) amplified DNA fragment from beta-globin gene and restriction enzyme Mnl 1. A 232bp DNA fragment was found to be associated with the Hb E mutation. 相似文献
10.
Elena Neiterman Christine Sheppard Souraiya Kassam Vanessa Bach Saman Husain 《Educational gerontology》2020,46(6):339-349
ABSTRACTIn the study of gerontology, fieldwork with older adults is often used to enhance students’ understanding of the aging process. While assignments based on interactions with older adults are a common practice in teaching students enrolled in gerontology studies, we know less about the impact of such activities on students from other disciplines. This paper summarizes students’ experiences with an assignment offered to a diverse cohort of undergraduate students who took a course in social gerontology. To complete this assignment, students had to interview an older adult, summarize the life story of the participant, apply a theoretical perspective to the older adult’s life story, and reflect on the process. Analyzing data derived from 72 assignments and 10 semi-structured interviews with students who were enrolled in the course, this paper examines students’ experiences with this assignment. Specifically, we identify what aspects of the assignment students found beneficial, what aspects they found challenging, and in what ways this assignment helped students to enhance their understanding of aging. Our findings suggest that students found it challenging to recruit an older adult for an interview and struggled with the semi-structured nature of the interview process. All students found the actual interview process to be extremely rewarding and beneficial for their learning. In discussion, we provide some recommendations on how to offer this type of assignment to a diverse group of students enrolling in the courses on social gerontology. 相似文献