排序方式： 共有59条查询结果，搜索用时 15 毫秒
1.
Farzana Shain 《Education 3-13》2016,44(1):8-18
ABSTRACTEducation researchers, policy-makers and practitioners in the UK have debated the question of what, and how much, schools can do to mitigate the effects of parental background on educational outcomes over the last half a century. A range of programmes, strategies and interventions have been implemented, and continue to be implemented in an effort to ‘break the link’ between socio-economic disadvantage and low educational outcomes, but educational inequalities have persisted. This paper draws on theoretical and empirical research to offer a new analysis of compensatory education in England across three main phases since the 1960s. 相似文献
2.
3.
Amna Khan Farzana Hayat Ahmad Muhammad Muddassir Malik 《Education and Information Technologies》2017,22(6):2767-2804
This study aimed to identify the impact of a game based learning (GBL) application using computer technologies on student engagement in secondary school science classrooms. The literature reveals that conventional Science teaching techniques (teacher-centered lecture and teaching), which foster rote learning among students, are one of the major concerns in Pakistan Education system. This leads to student disengagement in science lessons eventually resulting in student absenteeism and dropouts from the schools. This study consisted of five stages: (1) examining the impact of Digital Game-Based Learning (DGBL) and gamification on engagement, learning and gender difference, and literature related to using DGBL models for instructional design; (2) planning learning activities and developing a GBL application based on a specific content in Science; (3) conducting an intervention with a sample of 72 participants of 8th grade (aged 12–15) in a low cost private school of Pakistan following quasi-experimental research framework; (4) observing behaviour and emotions of the participants during science lessons; (5) conducting pre and post tests to assess the learning outcomes of participants followed by focus groups discussion. Analysis from Friedman test, Mann-Whitney U test, and Wilcoxon Signed Rank test show that the GBL application has a positive influence on student engagement. However, GBL application was not equally effective for all students since girls outperformed boys in terms of engagement and learning outcomes. This study gives insights into the development of better educational games to promote student learning. 相似文献
4.
Tiwari AK Mahdi AA Zahra F Chandyan S Srivastava VK Negi MP 《Indian journal of clinical biochemistry : IJCB》2010,25(4):411-418
The present study was conducted to investigate the oxidant–antioxidant status in iron deficient pregnant anemic women. One
hundred thirty pregnant women with iron deficiency anemia (IDA) were divided into three groups, namely mild (50), moderate
(50) and severe (30) anemic along with pregnant healthy women as controls (50). The complete blood count, plasma lipid peroxidation
products, enzymatic and non-enzymatic antioxidants were measured according to respective protocols. The levels of complete
blood count, iron, ferritin along with antioxidant enzymes namely catalase, superoxide dismutase, glutathione peroxidase,
glutathione reductase and reduced glutathione were significantly reduced in all IDA groups. However, the level of oxidized
glutathione, lipid peroxides, protein carbonyls, conjugated dienes were found significantly increased in all anemic patients.
Antioxidant vitamins, namely C, E and A were also found significantly decreased in IDA patients. On the basis of our results,
it may be concluded that IDA tends to increase the pro-oxidant components, which may result in various complications including
peroxidation of vital body molecules resulting in increased risk for pregnant women as well as fetus. 相似文献
5.
Singh PP Chandra A Mahdi F Roy A Sharma P 《Indian journal of clinical biochemistry : IJCB》2010,25(3):225-243
The antioxidants are essential molecules in human system but are not miracle molecules. They are neither performance enhancers
nor can prevent or cure diseases when taken in excess. Their supplemental value is debateable. In fact, many high quality
clinical trials on antioxidant supplement have shown no effect or adverse outcomes ranging from morbidity to all cause mortality.
Several Chochrane Meta-analysis and Markov Model techniques, which are presently best available statistical models to derive
conclusive answers for comparing large number of trials, support these claims. Nevertheless none of these statistical techniques
are flawless. Hence, more efforts are needed to develop perfect statistical model to analyze the pooled data and further double
blind, placebo controlled interventional clinical trials, which are gold standard, should be implicitly conducted to get explicit
answers. Superoxide dismutase (SOD), glutathione peroxidase and catalase are termed as primary antioxidants as these scavenge
superoxide anion and hydrogen peroxide. All these three enzymes are inducible enzymes, thereby inherently meaning that body
increases or decreases their activity as per requirement. Hence there is no need to attempt to manipulate their activity nor
have such efforts been clinically useful. SOD administration has been tried in some conditions especially in cancer and myocardial
infarction but has largely failed, probably because SOD is a large molecule and can not cross cell membrane. The dietary antioxidants,
including nutrient antioxidants are chain breaking antioxidants and in tandem with enzyme antioxidants temper the reactive
oxygen species (ROS) and reactive nitrogen species (RNS) within physiological limits. Since body is able to regulate its own
requirements of enzyme antioxidants, the diet must provide adequate quantity of non-enzymic antioxidants to meet the normal
requirements and provide protection in exigent condition. So far, there is no evidence that human tissues ever experience
the torrent of reactive species and that in chronic conditions with mildly enhanced generation of reactive species, the body
can meet them squarely if antioxidants defense system in tissues is biochemically optimized. We are not yet certain about
optimal levels of antioxidants in tissues. Two ways have been used to assess them: first by dietary intake and second by measuring
plasma levels. Lately determination of plasma/serum level of antioxidants is considered better index for diagnostic and prognostic
purposes. The recommended levels for vitamin A, E and C and beta carotene are 2.2–2.8 μmol/l; 27.5–30 μmol/l; 40–50 μmol/l
and 0.4–0.5 μmol/l, respectively. The requirement and recommended blood levels of other dietary antioxidants are not established.
The resolved issues are (1) essential to scavenge excess of radical species (2) participants in redox homeostasis (3) selective
antioxidants activity against radical species (4) there is no universal antioxidant and 5) therapeutic value in case of deficiency.
The overarching issues are (1) therapeutic value as adjuvant therapy in management of diseases (2) supplemental value in developing
population (3) selective interactivity of antioxidant in different tissues and on different substrates (4) quantitative contribution
in redox balance (5) mechanisms of adverse action on excess supplementation (6) advantages and disadvantages of prooxidant
behavior of antioxidants (7) behavior in cohorts with polymorphic differences (8) interaction and intervention in radiotherapy,
diabetes and diabetic complications and cardiovascular diseases (9) preventive behavior in neurological disorders (10) benefits
of non-nutrient dietary antioxidants (11) markers to assess optimized antioxidants status (12) assessment of benefits of supplementation
in alcoholics and heavy smokers. The unresolved and intriguing issues are (1) many compounds such as vitamin A and many others
possessing both antioxidant and non-antioxidant properties contribute to both the activities in vivo or exclusively only to
non-antioxidant activity and (2) since human tissues do not experience the surge of FR, whether there is any need to develop
stronger synthetic antioxidants. Theoretically such antioxidants may do more harm than good. 相似文献
6.
7.
Shrish Bhatnagar Farzana K. Beig Ashraf Malik 《Indian journal of clinical biochemistry : IJCB》2008,23(3):299-301
Adenosine deaminase and C-reactive protein in CSF were assessed in 72 cases of Tubercular meningitis, 24 cases of partially
treated pyogenic meningitis, 20 cases of Aseptic meningitis and 8 cases of febrile seizures. Mean Adenosine deaminase value
was 12.12±3.13 IU/L for Tubercular meningitis group. It was significantly higher (p<0.001) as compared to partially treated
pyogenic meningitis (5.39±2.70 IU/L) and aseptic meningitis (1.92±0.56 IU/L) groups. A combination of clinical criteria along
with biochemical test of Adenosine deaminase and C-reactive protein in CSF increased the sensitivity of diagnosing Tubercular
meningitis and differentiating it from other forms of meningitis at an early stage. 相似文献
8.
9.
10.
Faezeh Farivar Mahdi Aliyari Shoorehdeli Mohammad Teshnehlab 《Journal of The Franklin Institute》2012,349(7):2243-2267
Despite active research and significant progress in the last three decades on control of human eye movements, it remains challenging issue due to its applications in prosthetic eyes and robotics. Till now, no considerable investigation of this subject is presented in the interdisciplinary sciences. The goal of this paper is to present a distinguished survey of existing literature on the intelligent control of the human eye movements system applied in a huggable pet-type robot as a biomechatronic system.In this study, the basic knowledge of human eye movements control is explained to show how the neural networks in the brainstem control the human eye movements. The geometry and model of human eye movements system are investigated and this system is considered as a nonlinear control system. The specified model may only be an academic exercise. It can have scientific importance in understanding of the human movement system in general. Also, it can be useful for robotics.Intelligent methods such as artificial neural networks and fuzzy neural networks are proposed to control the human eye movements and numerical simulations are presented. It is discussed that the intelligent controls applied to control of human eye movements system are emulated from the neural controls in biological system. 相似文献