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排序方式: 共有289条查询结果,搜索用时 31 毫秒
1.
Michael Sponder Ioana-Alexandra Campean Michael Emich Monika Fritzer-Szekeres Brigitte Litschauer Jutta Bergler-Klein 《Journal of sports sciences》2017,35(21):2129-2134
Cathepsin S (CS) was shown to play a key role in cancer progression, atherosclerosis, heart valve disease, insulin resistance and diabetes mellitus. The present prospective study aimed to investigate the influence of sports on CS, interleukin-6 (Il-6) and high-sensitivity C-reactive protein (hsCRP) levels.Ninety-eight of 109 participants completed the study. Ergometries were performed at baseline and after 8 months to evaluate/quantify the performance gain. Blood samples were taken at baseline and every 2 months. CS was measured by ELISA (enzyme-linked immunosorbent assay). Compared to the control group (mean performance gain ?3.41 ± 4.62%) we observed a significant physical-activity-induced increase of CS levels (3.45–3.73 ng · ml?1; P = 0.027) and a significant decrease of Il-6 (2.43–1.91 pg · ml?1; P = 0.031) and hsCRP-levels (0.11–0.09 mg · dl?1; P = 0.001) in the intervention group (mean performance gain: 12.13 ± 6.32%). Furthermore, the tendency of the progression was significant for CS and Il-6 (P = 0.002/0.033).We could show a significant sports-induced decrease of the classic inflammation parameters hsCRP/Il-6, probably expressing a downregulation of permanently prevalent inflammation processes. Simultaneously CS levels increased significantly. Our results show that increasing CS amounts are not simply to equal with an enhanced inflammation status and might even have beneficial effects on inflammation and angiogenesis. 相似文献
2.
D P Sen Gupta 《Resonance》2007,12(3):54-69
Alternating Current (AC) is used all over the world today. In India we use AC at 50 Hz (cycles per second) and in USA and
Canada at 60 Hz. During the latter part of the 19th century, even during the early part of the 20th century, Direct Current
or DC was widely used. Had we continued with DC, electricity would not have been as widely available as it is today and its
use would have been cumbersome, costly and severely restricted. We owe it mainly to the Serbian genius Nikola Tesla that electricity
has reached almost every nook and corner of most continents. 相似文献
3.
Yashika Gupta V. Mallika D. K. Srivastava 《Indian journal of clinical biochemistry : IJCB》2005,20(1):87-94
Platelets play a vital role in the progression of atherosclerosis and thrombosis, a major cause of death worldwide. Platelets
are activated by many triggers like elevated LDL in blood resulting in aggregation and formation of plaque. The purpose of
this study was to investigate the effect of LDL and signal transduction inhibitor on the activation of platelets in Ischaemic
risk subjects. Platelets from IHD and hyperlipidemic subjects were hypersensitive to ADP, as higher levels of platelet aggregation
were observed in these groups. LDL from IHD hyperlipidemic subjects was more effective in activating platelets from any other
group. Ox-LDL was more effective in activating platelets than native-LDL as monitored by level of platelet aggregation induced
by PAF and thrombin. Calcium channel blocker, nifedipine and verapamil inhibited platelet aggregation at micromolar level.
Protein kinase inhibitor, staurosporine was effective in inhibiting ADP induced aggregation at nanomolar level. 相似文献
4.
Pushpendra KG Harindra SB Pawan LK Neeraj K Ajay K Reyazul RM Amita M Jitendra K 《Journal of Zhejiang University. Science. B》2007,8(11):807-814
Quantitative trait loci (QTL) analysis was conducted in bread wheat for 14 important traits utilizing data from four different mapping populations involving different approaches of QTL analysis. Analysis for grain protein content (GPC) sug- gested that the major part of genetic variation for this trait is due to environmental interactions. In contrast, pre-harvest sprouting tolerance (PHST) was controlled mainly by main effect QTL (M-QTL) with very little genetic variation due to environmental interactions; a major QTL for PHST was detected on chromosome arm 3AL. For grain weight, one QTL each was detected on chromosome arms 1AS, 2BS and 7AS. QTL for 4 growth related traits taken together detected by different methods ranged from 37 to 40; nine QTL that were detected by single-locus as well as two-locus analyses were all M-QTL. Similarly, single-locus and two-locus QTL analyses for seven yield and yield contributing traits in two populations respectively allowed detection of 25 and 50 QTL by composite interval mapping (CIM), 16 and 25 QTL by multiple-trait composite interval mapping (MCIM) and 38 and 37 QTL by two-locus analyses. These studies should prove useful in QTL cloning and wheat improvement through marker aided selection. 相似文献
5.
The article presents research results of a study aimed at determining the correlation between empathy understood as a personality disposition and general attitudes towards individuals with disability. The sample consisted of 300 special education teachers working with persons with intellectual disabilities in primary and secondary schools and institutions of rehabilitation, and 280 general education teachers working with able-bodied students in primary and secondary schools. Two instruments were used: Empathic Understanding of Other People Questionnaire, and the Scale of Attitudes towards Individuals with Disability. In the group of special education teachers, only Syndrome 2 of empathy was statistically significant for shaping the attitudes, whereas among teachers, Syndromes 1, 3 and 4 were significant. In Syndromes 1, 2 and 4, including the highest level of emotional, cognitive, motivational and communication aspects of empathy, the correlations were positive as expected. In the case of Syndrome 3, including the considerable level of cognitive empathy, the correlation was negative. 相似文献
6.
7.
The authors take up the hypothesis that distance education was also meant to facilitate the access of women to higher education. Recent studies carried out at the University for Distance Education at Hagen show that results do not always match expectations. By analysing in detail the causes for this partial failure, the authors come forward with some remedial proposals.
The authors are all members of the staff of Hagen University. 相似文献
8.
9.
Srivastava Himanshu Gupta Ankush Raveendran Aswathy 《Cultural Studies of Science Education》2022,17(2):301-330
Cultural Studies of Science Education - The M(East) ward of Mumbai is home to one of Asia’s largest open landfill sites. Waste, therefore, is a source of livelihood for millions of people... 相似文献
10.
Seema Gupta Rajesh Pandey Ranjan Katyal H. K. Aggarwal R. P. Aggarwal S. K. Aggarwal 《Indian journal of clinical biochemistry : IJCB》2005,20(1):67-71
The present study was conducted to evaluate some of the components of antioxidant defense system and oxidative damage in 20
male patients of alcoholic liver disease (ALD). The results were compared with 20 healthy male smokers and 20 healthy male
non-smokers volunteers. Patients were subjected to detailed clinical examination and laboratory investigations. Blood samples
were collected for estimating reduced glutathione (GSH), total thiols (T-SH) malondialdehyde (MDA), transaminases (AST, ALT),
glutathione-S-transferease (GST) and gammaglutamyl transferase (GGT). Serum aspartate amino transferase (AST)/alanine amino
transferase (ALT) ratio was significantly (p<0.01) reduced in ALD patients as compared to the controls. However, the core
of utility of MDA and GST was found to be significantly (p<0.01) increased in ALD patients compared to controls. There was
a significant negative correlation of MDA with both GSH and TSH. Plasma GGT levels were significantly (p<0.01) increased in
alcoholics and the enzyme showed a significant positive correlation with MDA. These results give enough evidence of increased
oxidative stress and compromised antioxidant defense system in patients with ALD. 相似文献