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Analytical expressions are derived from a single symmetrical relay feedback test for the identification of open loop stable and unstable non-minimum phase processes. The second derivative of the limit cycle output helps in finding the time delay of the process. The derived expressions can be used to identify the process models with up to five unknowns. The effectiveness of the proposed identification method is verified through different simulation results. 相似文献
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D. P. Neupane S. Majhi L. Chandra S. Rijal Nirmal Baral 《Indian journal of clinical biochemistry : IJCB》2008,23(1):95-97
A glutathione redox cycle is a major antioxidant defense system for the detoxification of reactive oxygen species within erythrocytes.
Reactive oxygen species such as superoxide anions, hydrogen peroxide and hydroxyl radicals are generated as a host defense
mechanism for killing of engulfed Leishmania donovani, a causative agent of visceral leishmaniasis, are capable of damaging
lipids and other biomolecules when produced in excess. Erythrocytes are most vulnerable to Reactive oxygen species. In present
study we aimed to evaluate erythrocyte reduced glutathione (GSH) levels as an antioxidant and erythrocyte malondialdehyde
(MDA) as a marker of lipid peroxidation. The study included twenty-five Visceral leishmaniasis patients and they were followed
up after their complete chemotherapy with antileishmanial drugs (sodium stibogluconate) for 30 days. Forty six age and sex
matched healthy individuals were taken as controls. GSH levels in erythrocytes of visceral leishmaniasis patients were increased
in spite of significant increased erythrocyte MDA as compared to controls. Whereas erythrocyte GSH and MDA levels of follow
up patients were decreased as compared to patients before treatment groups. We concluded that visceral leishmaniasis patients
are in oxidative stress which most likely induces the endogenous antioxidant such as GSH or its poor utilization by cells. 相似文献
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Pranab S. Basu Ramdhan Majhi Sudip Chatterjee Sandip K Batabyal 《Indian journal of clinical biochemistry : IJCB》2000,15(2):119-123
A method has been developed to separate and identify thyroglobulin autoantibody (TgAb) and thyroid peroxidase autoantibody
(TPOAb) in serum obtained from normal and autoimmune thyroid diseases using phenyl Sepharose CL-4B hydrophobic column. The
protein peaks obtained from hydrophobic column were identified as TgAb and TPOAb by comparing the elution profile of commercially
purified standard thyroid autoantibodies. The similarity of the inhibitory effects of eluted proteins and of standard thyroid
autoantibodies on lectin concanavalin A-RBC interaction confirmed the separation of TPO-Ab and TgAb by the hydrophobic, column.
The eluted fractions from the hydrophobic column were estimated by the radio immunoassay (RIA) to confirm the presence of
both auto-antibodies. This hydrophobic column method offers an advantage of visual inspection of this autoantibodies by graphic
representation of peak height along with their estimation in autoimmune thyroid disorders. 相似文献
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