A kinematic analysis of the spine during rugby scrummaging on natural and synthetic turfs     

Ramesh Swaminathan  Jonathan M. Williams  Michael D. Jones 《Journal of sports sciences》2016,34(11):1058-1066

Artificial surfaces are now an established alternative to grass (natural) surfaces in rugby union. Little is known, however, about their potential to reduce injury. This study characterises the spinal kinematics of rugby union hookers during scrummaging on third-generation synthetic (3G) and natural pitches. The spine was sectioned into five segments, with inertial sensors providing three-dimensional kinematic data sampled at 40 Hz/sensor. Twenty-two adult, male community club and university-level hookers were recruited. An equal number were analysed whilst scrummaging on natural or synthetic turf. Players scrummaging on synthetic turf demonstrated less angular velocity in the lower thoracic spine for right and left lateral bending and right rotation. The general reduction in the range of motion and velocities, extrapolated over a prolonged playing career, may mean that the synthetic turf could result in fewer degenerative injuries. It should be noted, however, that this conclusion considers only the scrummaging scenario.  相似文献   

Building technology-based, learner-centered classrooms: The evolution of a professional development framework     

Chandra Hawley Orrill 《Educational technology research and development : ETR & D》2001,49(1):15-34

This study examined issues in supporting middle-school teachers to become more learner centered when implementing computer-based, workplace simulations in their classrooms. Specifically, this report focuses on a participant observation study of two teachers to develop and evolve a framework for professional development. The framework was developed based on prior professional development efforts, information on developing learner-centered classrooms, and data about teacher change. The framework included five key pieces: (a) reflection, (b) proximal goals, (c) collegial support groups, (d) one-on-one feedback, and (e) support materials for the teachers. The foundation for the framework was a belief that change is individual and needs to be supported in context and over time. The data included field observations as the teachers used the simulations in their classrooms made by the author and three outside observers, and interviews with each teacher following her use of the simulation program. During the four-month study, the original framework evolved in response to the data collected. The final version of the framework focuses on the professional developer working with teachers to develop reflective skills. Proximal goals became a focusing tool for reflection after teachers had begun to develop their reflective skills. The interplay between reflection and proximal goals was enhanced by outside resources, one-on-one feedback, and collegial group meetings. The work reported here was comp;eted as part of a dissertation conducted at Indiana University’s Center for Innovation in Assessment, and was supported in part by grants from the Andrew W. Mellon Foundation and the Russell Sage Fundation. The school and participant names have been changed to protect their identity. All researcher names are actual.  相似文献   

Cardioprotective activity of synthetic guggulsterone (E and Z-isomers) in isoproterenol induced myocardial ischemia in rats: A comparative study     

Ramesh Chander  Farhan Rizvi  A. K Khanna  Ram Pratap 《Indian journal of clinical biochemistry : IJCB》2003,18(2):71-79

Guggulsterone, a mixture of cis (E) and trans (Z) isomers (7∶3 w/w) was synthesized from 16-DPA. The isomers were separated by column chromatography and evaluated for cardioprotective and antioxidant activities. Myocardial necrosis induced by isoproterenol in rats caused marked increase in serum creatine phosphokinase and glutamate pyruvate transaminase. Simultaneously in ischemic heart, phospholipase, xanthine oxidase and lipid peroxides were enhanced following depletion of glycogen, phospholipids and cholesterol. Treatment with guggulsterone and its both isomers at the dose of 50 mg/kg po., significantly protected cardiac damage as assessed by the reversal of blood and heart biochemical parameters in ischemic rats. The cardioprotective activity of guggulsterone and of both the isomers were compared with that of gemfibrozil at the same doses. Guggulsterone and both the isomers at tested concentrations (5–20mM) inhibited oxidative degradation of lipids in human low-density lipoprotein and rat liver microsomes induced by metal ionsin vitro. The drug counteracted against the generation of superoxide anions (O₂) and hydroxyl radicals (OH⁻) in non-enzymic test systems. It is suggested that cardioprotective and antioxidant activities of synthetic guggulsterone and guggulsterone obtained from gum resinCommiphora mukul that contains isomers E & Z in the ratio of 46∶54w/w are the same.  相似文献   

The genesis of Curzon's University eform: 1899–1905     

Suresh Chandra Ghosh 《Minerva》1988,26(4):463-492

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Evaluation of Sigma-Metric and Application of Quality Tools in Clinical Laboratory of a Tertiary Care Hospital     

Puja kumari Jha  Nirupama Sharma  Juhee Chandra  Rachna Agarwal 《Indian journal of clinical biochemistry : IJCB》2021,36(3):337

Variability in analytical performance of some analyte indicated the need of evaluation of quality plan of our laboratory. We tried to put the same degree of effort into our quality metrics as we put into the laboratory processes themselves. Application of six sigma methodologies improve the quality by focusing on the root causes of the problems in performance and analyzing by flowcharts, fishbone diagrams and other quality tools. Sigma metric was calculated for laboratory parameters for a period of 8 months during 2018–19. The analytes with poor sigma metric were free Thyroxine (FT3, FT4), Sodium, Calcium and Magnesium. Sigma metric of free Thyroxine (FT3, FT4), Sodium, Calcium and Magnesium were below 3. A road map for process improvement was designed with DMAIC (Define-Measure-Analyze-Improve-Control) model to solve the issue. Possible causes for low analytical performance of the particular analytes were depicted in Fishbone diagram. The Fishbone analysis identified the water quality issues with electrolyte analysis while high ambient temperature was culprit for poor assay performance of free Thyroxine. Sigma metric of the analytical performance was assessed once again after root cause analysis. Sigmametric showed marked improvement in control phase. Identification of problems led to reduction in non value added work leading to adequate resource utilization by addressing the priority issue. Therefore, DMAIC tool with Fish bone model analysis can be recommended as a well suited method for troubleshooting in poor performance of laboratory parameter.  相似文献   

Role of MRI in medical diagnostics     

Rashmi Rao  Ramesh Venkatesan  Sairam Geethanath 《Resonance》2015,20(11):1003-1011

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Program Review: Perspectives on an Improvement-Oriented Process     

Caleb J. Keith  Kristine Brunovska Karnick  Chandra L. Kohler  Eric J. Teske  A. Sonia Ninon 《Assessment Update》2023,35(5):6-14

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What Tahrir Square Has Done for Social Media: A 2012 Snapshot in the Struggle for Political Power in Egypt     

Ramesh Srinivasan 《The Information Society》2014,30(1):71-80

While the debate rages on the role of social media technologies in the initial days of the Egyptian revolution of 2011, a more relevant research question today is the role of social media within an increasingly contested and turbulent political sphere. This article identifies three key modes by which social media is being exploited to impact political power, and uncovers the salience of each of these through 2 years of multisited ethnographies and interviews. First, I argue that political actors across the political spectrum, from liberals to Muslim Brotherhood (Ikhwan), are using technologies to build wider ranging, heterogeneous, and diverse networks of supporters, expanding their base from a more historically homogeneous core support group. Second, I argue that actors are working to build bridges between older and newer media platforms, recognizing that each platform is increasingly being shaped by the other. Finally, I describe some of the ways that technology is being used by activists to subvert their competition, promoting campaigns of misinformation and hacking at the expense of others.  相似文献   

Preparing a Data Scientist: A Pedagogic Experience in Designing a Big Data Analytics Course          下载免费PDF全文

Daniel Adomako Asamoah  Ramesh Sharda  Amir Hassan Zadeh  Pankush Kalgotra 《Decision Sciences Journal of Innovative Education》2017,15(2):161-190

In this article, we present an experiential perspective on how a big data analytics course was designed and delivered to students at a major Midwestern university. In reference to the MSIS 2006 Model Curriculum, we designed this course as a level 2 course, with prerequisites in databases, computer programming, statistics, and data mining. Students in the class were mostly seniors or at the graduate level, and had a strong technical and quantitative background. We include details of concepts covered in the course, as well as summaries of four major sample course assignments used. Some of the concepts covered include large‐scale data collection and management using the Hadoop ecosystem, stream mining, visual analytics, and social network analytics. Besides Hadoop, the course also introduced various IBM and Teradata big data tools. We show how the course modules align with the intended learning goals and course objectives. A post‐course survey indicated that the structure and organization of the course helped students clearly and concisely assimilate the course content.  相似文献   

Effect of <Emphasis Type="SmallCaps">l</Emphasis>-Thyroxine on Micronuclei Frequency in Peripheral Blood Lymphocytes in Clinical and Experimental Conditions     

Yogita S. Raut  Uma S. Bhartiya  Purushottam Kand  Rohini W. Hawaldar  Ramesh V. Asopa  Lebana J. Joseph  MGR Rajan 《Indian journal of clinical biochemistry : IJCB》2016,31(1):99-103

The aim was to study the genotoxic effect of high concentration of thyroxine (T₄) in vivo in peripheral blood lymphocytes (PBL) of the patients suffering from thyroid disorders. The effect was compared by performing in vitro experiments with addition of increasing concentration of T₄ (0.125–1 µM) in whole blood samples from healthy donors. Cytokinesis-blocked micronuclei (CBMN) assay method was used to assess the DNA damage in the PBL. The study included 104 patients which were grouped as control (n = 49), hyperthyroid (n = 31) and hypothyroid (n = 24). A significant increase in micronuclei (MN) frequency was observed in hyperthyroid patients when compared with the hypothyroid and euthyroid group thereby suggesting increased genotoxicity in hyperthyroidism (p < 0.001). A significant increase in MN frequency was observed at T₄ concentration of 0.5 µM and above when compared to lower T₄ concentrations (0.125 and 0.25 µM) and basal in in vitro experiments (p = 0.000). The results indicate that the T₄ in normal concentration does not exhibit the genotoxic effect, as observed in both the in vivo and in vitro experiments. The toxicity of T₄ increases at and above 0.5 μM concentration in vitro. Therefore acute T₄ overdose should be handled promptly and effectively so as to avoid the possible genotoxic effect of high concentration of T₄ in vivo.  相似文献