Carnosine in health and disease     

Guilherme Giannini Artioli  Craig Sale  Rebecca Louise Jones 《European Journal of Sport Science》2019,19(1):30-39

Abstract

Carnosine was originally discovered in skeletal muscle, where it exists in larger amounts than in other tissues. The majority of research into the physiological roles of carnosine have been conducted on skeletal muscle. Given this and the potential for muscle carnosine content to be increased with supplementation, there is now a large body of research examining the ergogenic effects (or otherwise) of carnosine. More recent research, however, points towards a potential for carnosine to exert a wider range of physiological effects in other tissues, including the brain, heart, pancreas, kidney and cancer cells. Taken together, this is suggestive of a potential for carnosine to have therapeutic benefits in health and disease, although this is by no means without complication. Herein, we will provide a review of the current literature relating to the potential therapeutic effects of carnosine in health and disease.  相似文献   

Roadkill on the electronic highway? The threat to the mathematical literature     

Frank Quinn 《Publishing Research Quarterly》1995,11(2):20-28

This article begins with an analysis of reliability and usability in the mathematical literature. Mathematical practice is seen to be adapted to very high standards in these respects, and quite sensitive to even modest declines in quality. Unfortunately most scenarios for the transition to electronic publication suggest serious loss of quality. This is a problem special to mathematics: other sciences are adapted to lower standards, and should be much less sensitive to changes. Some ways to prevent this decline are suggested. A condensed version of this article appeared inNotices of the American Mathematical Society, 42, 1, January 1995. Published with permission of the American Mathematical Society.  相似文献   

Womentalkin': A reader's theater performance of teachers' stories     

Natalie Adams  Tammie Causey  Mary-ELLEN Jacobs  Petra Munro  Molly Quinn  Ann Trousdale 《International journal of qualitative studies in education》2013,26(3):383-395

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Stability in Mother-Child Interactions from Infancy through Adolescence     

Else-Quest NM  Clark R  Owen MT 《Parenting, science and practice》2011,11(4):280-287

OBJECTIVE: The current study examines homotypic stability in mother-child interactions, applying similar rating scales of mother-child interactions at 1 and 4.5 years, and heterotypic stability from 1 to 13 years and 4.5 to 13 years, using conceptually similar but not identical rating scales at age 13. DESIGN: We coded videotaped mother-child interactions in 202 families when children were 1, 4.5, and 13 years of age during age-appropriate and developmentally salient structured tasks for relationship quality. RESULTS: Multiple regression analyses controlled for the effects of child birth order and gender as well as maternal age and education. Maternal and dyadic, but not child, mother-child interaction qualities at 1 year significantly predicted similar or equivalent constructs at 4.5 and 13 years. Heterotypic stability from 1 to 13 years was partially or fully mediated by the same constructs at 4.5 years. CONCLUSIONS: Maternal behaviors showed a pattern of homotypic and heterotypic stability, whereas dyadic behaviors were somewhat less stable. Child behaviors showed evidence of both homotypic and heterotypic instability.  相似文献   

Real education in non-real time: The use of electronic message systems for instruction     

Clark N. Quinn  Hugh Mehan  James A. Levin  Steven D. Black 《Instructional Science》1983,11(4):313-327

Education in different communication media takes place with functional differences that have consequences for the course of instructional interaction. In this paper, we examine instructional interaction among people using a computer-based electronic message system, contrasting it with conventional face-to-face discussion in a college level class. Interaction via the non-real time message system contained multiple “threads of discourse,” a higher proportion of student turns to teacher turns, and other deviations from the “initiation-response-evaluation” sequences usually found in face-to-face classroom interactions. Based on the results of our contrast, we describe ways to organize instruction using electronic message systems to take advantage of new properties and to avoid shortcomings of these new instructional media.  相似文献   

A leisure counseling model for addicted persons     

Quinn M. Pearson 《Journal of Career Development》1992,19(1):13-24

Conclusion This leisure counseling model provides a general framework for the counseling process rather than a strict guideline. While some clients may progress orderly through the stages, other clients may move back and forth amongst different stages. The specific counseling needs of each client should guide the client's progress through the model accordingly. In short, within the model's framework the counseling process has a great deal of flexibility.The purpose of this article has been to emphasize the importance of leisure counseling for addicted persons and to present a corresponding model that can supplement existing programs and support groups. Thus, the model is designed in such a way that it can be implemented in either individual or group settings. Whatever the particular application of this leisure counseling model, it adds an important extra dimension to existing addiction treatment approaches.The importance of leisure counseling for addicted persons in recovery cannot be overemphasized. Because the addiction was the center of their lives, recovering addicts must forge a new lifestyle without their drug of choice: their best friend and greatest source of security and reassurance. Recognizing their struggle, the addiction leisure counseling model should help counselors facilitate this transition by enabling addicted clients to begin using leisure to satisfy many of their unmet needs.  相似文献   

Growing the Profession: Mentoring Undergraduates for Librarianship     

Connie Lamb  Brittany Hendricks  Quinn D. Galbraith 《College & Undergraduate Libraries》2015,22(2):123-148

Since 2007, Brigham Young University Library has provided a paid internship program for undergraduates that allows them to work with a librarian in an academic setting to help them decide if they wish to pursue a master's degree in Library Science. This article describes the internship program and provides results of surveys given to both interns and library mentors regarding their expectations and outcomes. In a new addition to the program, interns now meet with multiple librarians to gain a broad understanding of library work and how different library areas function together.  相似文献   

Reach Out! Highlighting Collections and Expanding Outreach to Non-Traditional Communities across Academia     

Stephanie Beene  Sarah Kostelecky  Todd Quinn 《The Reference Librarian》2019,60(1):29-50

As the number of reference questions continues to decline across academic libraries, innovative models have been developed to highlight collections and reach underserved communities. This article describes four outreach models at the University of New Mexico University Libraries, including satellite outreach services, pop-up book trucks and events, and relationship building at various locations on and off campus. The authors describe innovative approaches including curated browsing experiences and relationship marketing to underserved communities. Lessons learned, future approaches, and the benefits of each model will also be explored.  相似文献   

Towards shaping the field: theorising the knowledge in a formal course for academic developers     

Jo-Anne Vorster  Lynn Quinn 《高等教育研究与发展》2015,34(5):1031-1044

In recent years there have been calls both for building the knowledge base of academic development (AD) and for systematic induction of newcomers to the field if AD is to advance as a professional and an academic field. Despite the importance and complexity of AD, induction of novice academic developers remains mostly informal and predominantly focuses on the practices of the field. We argue that more-experienced academic developers have an obligation to provide formal and systematic routes into the field and its knowledge base than is currently the case. One way of doing this is through offering a formal course for growing the next generation of academic developers. Such a course could equip newcomers with a more solid and shared knowledge base, thus contributing to shaping the epistemic spine of AD. In this paper, using Maton's Legitimation Code Theory, we offer an analysis of an existing course aimed at equipping novices with the theoretical and practical knowledge to enable them to solve some of the problems in higher education. From this analysis have emerged general principles that could inform the selection, sequencing and pacing of knowledge in a formal course for academic developers.  相似文献   

Learning in First-Year Biology: Approaches of Distance and On-Campus Students   总被引：1，自引：0，他引：1  

Frances Catherine Quinn 《Research in Science Education》2011,41(1):99-121

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