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Michael Sponder Ioana-Alexandra Campean Michael Emich Monika Fritzer-Szekeres Brigitte Litschauer Jutta Bergler-Klein 《Journal of sports sciences》2017,35(21):2129-2134
Cathepsin S (CS) was shown to play a key role in cancer progression, atherosclerosis, heart valve disease, insulin resistance and diabetes mellitus. The present prospective study aimed to investigate the influence of sports on CS, interleukin-6 (Il-6) and high-sensitivity C-reactive protein (hsCRP) levels.Ninety-eight of 109 participants completed the study. Ergometries were performed at baseline and after 8 months to evaluate/quantify the performance gain. Blood samples were taken at baseline and every 2 months. CS was measured by ELISA (enzyme-linked immunosorbent assay). Compared to the control group (mean performance gain ?3.41 ± 4.62%) we observed a significant physical-activity-induced increase of CS levels (3.45–3.73 ng · ml?1; P = 0.027) and a significant decrease of Il-6 (2.43–1.91 pg · ml?1; P = 0.031) and hsCRP-levels (0.11–0.09 mg · dl?1; P = 0.001) in the intervention group (mean performance gain: 12.13 ± 6.32%). Furthermore, the tendency of the progression was significant for CS and Il-6 (P = 0.002/0.033).We could show a significant sports-induced decrease of the classic inflammation parameters hsCRP/Il-6, probably expressing a downregulation of permanently prevalent inflammation processes. Simultaneously CS levels increased significantly. Our results show that increasing CS amounts are not simply to equal with an enhanced inflammation status and might even have beneficial effects on inflammation and angiogenesis. 相似文献
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Henry I. Braun 《Journal of Educational Measurement》1988,25(3):171-191
Extracting policy-relevant information from large national surveys of educational achievement is ordinarily a nontrivial task. It is made more treacherous when the data are expressed on scales that are not uniquely determined. The paper begins with a critical analysis of a recent attempt to interpret the findings on reading achievement obtained by the National Assessment of Educational Progress (NAEP). It then describes a new approach to the quantification and interpretation of change and demonstrates its appropriateness for repeated cross-sectional designs such as NAEP. Limitations imposed by the survey design and the nature of the measurements are highlighted 相似文献
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Marion Dresner Corinne Handelman Steven Braun Gretchen Rollwagen-Bollens 《Environmental Education Research》2015,21(7):991-1010
We conducted surveys of adults participating in municipally sponsored volunteer events in the Portland, OR metropolitan area in order to understand the range of attitudes and behaviors associated with volunteer work. We sampled 172 individuals in 18 events from February to June 2012. Principal components and factor analyses of survey responses identified three groups based on annual frequency of participation in stewardship events: first-time volunteers, mid-level volunteers (3–10 events per year), and frequent volunteers (>10 events per year). Our analyses revealed three main factors that explained the variation in survey response for the three volunteer groups: environmental identity, private pro-environmental behavior, and civic engagement. All three factors were positively correlated with frequency of participation in stewardship events, with the most frequent volunteers indicating the highest degree of attention to environmental issues, environmental identity, and self-reported pro-environmental behaviors. Frequent volunteers were more likely to feel personally attached to their local environment, believe that their efforts help solve environmental problems, and enjoy being part of community efforts. These results suggest that stewardship activities provide opportunities for volunteers to interact with others while working collectively toward restoring and maintaining parks, which may contribute to more resilient communities. 相似文献
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In the time between its founding and the fall of the wall in November 1989, more than three million people left the German Democratic Republic, many of them illegally and under dangerous circumstances. The party leadership perceived this mass exodus of its citizens as one of the major threats for the real socialist regime.1‘Republikflucht’, as this move from East to West was called by the party leadership, was the reason for the two most important hiatuses in Eastern German history: the first result was that the SED leadership built the wall in August 1961. Many years later, in the fall of 1989, the situation culminated, when a flood of desperate refugees tried to escape to the Federal Republic of Germany via Hungary, Poland and Czechoslovakia, thus effectively hurrying along the regime's demise. The world of sports, too, was considerably affected by this phenomenon. The following essay shall offer a short historical summary of the different reasons and routes Eastern German top athletes chose for their escape. Examples from various decades show that in spite of individual circumstances certain similarities in pattern can be made out, especially in respect to the way the government dealt with these cases of ‘treason’. 相似文献
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Vandermoere F Blanchemanche S Bieberstein A Marette S Roosen J 《Public understanding of science (Bristol, England)》2011,20(2):195-206
In spite of great expectations about the potential of nanotechnology, this study shows that people are rather ambiguous and pessimistic about nanotechnology applications in the food domain. Our findings are drawn from a survey of public perceptions about nanotechnology food and nanotechnology food packaging (N = 752). Multinomial logistic regression analyses further reveal that knowledge about food risks and nanotechnology significantly influences people's views about nanotechnology food packaging. However, knowledge variables were unrelated to support for nanofood, suggesting that an increase in people's knowledge might not be sufficient to bridge the gap between the excitement some business leaders in the food sector have and the restraint of the public. Additionally, opposition to nanofood was not related to the use of heuristics but to trust in governmental agencies. Furthermore, the results indicate that public perceptions of nanoscience in the food domain significantly relate to views on science, technology, and nature. 相似文献
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Dietmar Braun 《Minerva》2012,50(4):471-491
This article improves our understanding of the reasons underlying the intellectual migration of scientists from existing cognitive domains to nascent scientific fields. To that purpose we present, first, a number of findings from the sociology of science that give different insights about scientific migration. We then attempt to bring some of these insights together under the conceptual roof of an actor-based approach linking expected utility and diffusion theory. Intellectual migration is seen as the choice of scientists who decide under uncertainty and on the base of estimations about probabilities, costs, and benefits of the migration. The resulting choice model can be used as a heuristic base for further exploration of the subject. 相似文献